{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T16:41:35Z","timestamp":1774284095258,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"College of pharmacy of Dalian Medical University"},{"name":"Second Affiliated Hospital of Dalian Medical University"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.etap.2017.06.025","type":"journal-article","created":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T12:46:27Z","timestamp":1498913187000},"page":"120-124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis"],"prefix":"10.1016","volume":"54","author":[{"given":"Yi","family":"He","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-zhi","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-shu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingping","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-na","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng-tao","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2017.06.025_bib0005","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1046\/j.1365-2141.2003.04108.x","article-title":"Mutational analysis of class III receptor tyrosine kinases (C-KIT, C-FMS, FLT3) in idiopathic myelofibrosis","volume":"120","author":"Abu-Duhier","year":"2003","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.etap.2017.06.025_bib0010","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/ncomms1734","article-title":"Activation of canonical Wnt signalling is required for TGF-\u03b2-mediated fibrosis","volume":"3","author":"Akhmetshina","year":"2011","journal-title":"Nat. Commun."},{"key":"10.1016\/j.etap.2017.06.025_bib0015","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.taap.2016.04.016","article-title":"Resveratrol protects the ovary against chromium-toxicity by enhancing endogenous antioxidant enzymes and inhibiting metabolic clearance of estradiol","volume":"303","author":"Banu Sakhila","year":"2016","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.etap.2017.06.025_bib0020","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.urology.2013.01.053","article-title":"Periurethral fibrosis secondary to prostatic inflammation causing lower urinary tract symptoms: a prospective cohort study","volume":"81","author":"Cantiello","year":"2013","journal-title":"Urology"},{"key":"10.1016\/j.etap.2017.06.025_bib0025","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1002\/mrd.22430","article-title":"The SCF\/c-KIT system in the male: survival strategies in fertility and cancer Mol","volume":"81","author":"Cardoso","year":"2014","journal-title":"Reprod. Dev."},{"key":"10.1016\/j.etap.2017.06.025_bib0030","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1749-6632.2010.05848.x","article-title":"Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease","volume":"1215","author":"Csiszar","year":"2011","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.etap.2017.06.025_bib0035","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/path.4177","article-title":"Essential role of stem cell factor\u2013c-Kit signalling pathway in bleomycin-induced pulmonary fibrosis","volume":"230","author":"Ding","year":"2013","journal-title":"J. Pathol."},{"key":"10.1016\/j.etap.2017.06.025_bib0040","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1159\/000112518","article-title":"Stem cell factor in a rat model of serum nephrotoxic nephritis","volume":"108","author":"El Kossi","year":"2008","journal-title":"Nephron Exp. Nephrol."},{"key":"10.1016\/j.etap.2017.06.025_bib0045","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1093\/infdis\/jiq099","article-title":"Tissue inhibitor of matrix-metalloprotease1 predicts risk of hepatic Fibrosis in human schistosoma japonicum infection","volume":"203","author":"Fabre","year":"2011","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.etap.2017.06.025_bib0050","first-page":"502","article-title":"Normal peripheral prostate stromal cells stimulate prostate cancer development: roles of c-kit signal","volume":"7","author":"Guo","year":"2015","journal-title":"Transl Androl Urol ."},{"key":"10.1016\/j.etap.2017.06.025_bib0055","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jhep.2015.08.014","article-title":"Collagen and tissue turnover as a function of age: implications for fibrosis","volume":"64","author":"Karsdal","year":"2016","journal-title":"J. Hepatol."},{"key":"10.1016\/j.etap.2017.06.025_bib0060","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1002\/pros.21191","article-title":"The effect of estrogen supplementation on cell proliferation and expression of c-kit positive cells in the rat prostate","volume":"70","author":"Kusljic","year":"2010","journal-title":"Prostate"},{"key":"10.1016\/j.etap.2017.06.025_bib0065","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1152\/physrev.00046.2011","article-title":"Stem cell factor receptor\/c-Kit: from basic science to clinical implications","volume":"92","author":"Lennartsson","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.etap.2017.06.025_bib0070","first-page":"215","article-title":"Ambulatory urodynamic monitoring of external urethral sphincter behavior in chronic prostatitis patients","volume":"1","author":"Liao","year":"1999","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.etap.2017.06.025_bib0075","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.cbi.2014.12.031","volume":"227","author":"Liu","year":"2015","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.etap.2017.06.025_bib0080","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.juro.2012.06.007","article-title":"Prostatic fibrosis is associated with lower urinary tract symptoms","volume":"188","author":"Ma","year":"2012","journal-title":"J. Urol."},{"key":"10.1016\/j.etap.2017.06.025_bib0085","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1084\/jem.20100321","article-title":"Lnk-dependent axis of SCF\u2013cKit signal for osteogenesis in bone fracture healing","volume":"207","author":"Matsumoto","year":"2010","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.etap.2017.06.025_bib0090","doi-asserted-by":"crossref","first-page":"e0158357","DOI":"10.1371\/journal.pone.0158357","article-title":"Resveratrol-mediated repression and reversion of prostatic myofibroblast phenoconversion","volume":"11","author":"Mehrnaz","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.etap.2017.06.025_bib0095","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1161\/CIRCRESAHA.109.210088","article-title":"Nerve growth factor promotes cardiac repair following myocardial infarction","volume":"106","author":"Meloni","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.etap.2017.06.025_bib0100","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.eururo.2007.11.026","article-title":"The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial","volume":"54","author":"Nickel","year":"2008","journal-title":"Eur. Urol."},{"key":"10.1016\/j.etap.2017.06.025_bib0105","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.neo.2016.04.002","article-title":"A positive TGF-\u03b2\/c-KIT feedback loop drives tumor progression in advanced primary liver cancer","volume":"18","author":"Rojas","year":"2016","journal-title":"Neoplasia"},{"key":"10.1016\/j.etap.2017.06.025_bib0110","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000089720","article-title":"a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats","volume":"76","author":"Sharma","year":"2006","journal-title":"Pharmacology"},{"key":"10.1016\/j.etap.2017.06.025_bib0115","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1172\/JCI200420001","article-title":"Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury","volume":"113","author":"Sun","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.etap.2017.06.025_bib0120","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1872-034X.2010.00647.x","article-title":"Hepatocyte growth factor mobilizes and recruits hematopoietic progenitor cells into liver through a stem cell factor-mediated mechanism","volume":"40","author":"Tajima","year":"2010","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.etap.2017.06.025_bib0125","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1021\/jf903210q","article-title":"Regioselective lipase-catalyzed synthesis of 3-o-acyl derivatives of resveratrol and study of their antioxidant properties","volume":"58","author":"Torres","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.etap.2017.06.025_bib0130","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1002\/ijc.25788","article-title":"Vargas1 Markers of fibrosis and epithelial to mesenchymal transition demonstrate field cancerization in histologically normal tissue adjacent to breast tumors","volume":"129","author":"Trujillo","year":"2011","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.etap.2017.06.025_bib0135","doi-asserted-by":"crossref","first-page":"e287","DOI":"10.1016\/j.juro.2015.02.1210","article-title":"MP25-07 prostatic inflammation evokes upergulation of neurotrophins in sensory ganglia: possible contribution to dysfunctional voiding","volume":"193","author":"Tyagi","year":"2015","journal-title":"J. Urol."},{"key":"10.1016\/j.etap.2017.06.025_bib0140","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1161\/01.RES.0000243210.79654.fd","article-title":"Stem cell factor deficiency is vasculoprotective: unraveling a new therapeutic potential of imatinib mesylate","volume":"99","author":"Wang","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.etap.2017.06.025_bib0145","doi-asserted-by":"crossref","first-page":"e100770","DOI":"10.1371\/journal.pone.0100770","article-title":"Prostatic inflammation induces fibrosis in a mouse model of chronic bacterial infection","volume":"9","author":"Wong","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.etap.2017.06.025_bib0150","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/annrheumdis-2014-205740","article-title":"Sirt1 regulates canonical TGF-[beta] signalling to control fibroblast activation and tissue fibrosis","volume":"75","author":"Zerr","year":"2016","journal-title":"Ann. Rheum. Dis."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668917301722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668917301722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T13:55:56Z","timestamp":1535637356000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668917301722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":30,"alternative-id":["S1382668917301722"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2017.06.025","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2017.06.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}