{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:11:32Z","timestamp":1792145492608,"version":"4.4.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81660526"],"award-info":[{"award-number":["81660526"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Technology Department Fund of Guizhou Province","award":["[2016] 1091"],"award-info":[{"award-number":["[2016] 1091"]}]},{"name":"Science and Technology Department Fund of Guizhou Province","award":["[2017] 1077"],"award-info":[{"award-number":["[2017] 1077"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.etap.2018.07.012","type":"journal-article","created":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T20:49:50Z","timestamp":1532465390000},"page":"188-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Postnatal low-concentration arsenic exposure induces autism-like behavior and affects frontal cortex neurogenesis in rats"],"prefix":"10.1016","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7269-545X","authenticated-orcid":false,"given":"Hao","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihe","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxia","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.etap.2018.07.012_bib0005","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.etap.2015.09.016","article-title":"Arsenic and human health effects: a review","volume":"40","author":"Abdul","year":"2015","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.etap.2018.07.012_bib0010","doi-asserted-by":"crossref","first-page":"e808","DOI":"10.1002\/brb3.808","article-title":"Divergent anomaly in mesocorticolimbic dopaminergic circuits might be associated with different depressive behaviors, an animal study","volume":"7","author":"Bai","year":"2017","journal-title":"Brain Behav."},{"issue":"12","key":"10.1016\/j.etap.2018.07.012_bib0015","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1007\/s00204-017-2100-0","article-title":"Metal chelators and neurotoxicity: lead, mercury, and arsenic","volume":"91","author":"Bjorklund","year":"2017","journal-title":"Arch. Toxicol."},{"issue":"3-4 Suppl. 1","key":"10.1016\/j.etap.2018.07.012_bib0020","first-page":"14","article-title":"Studies on markers of exposure and early effect in areas with arsenic pollution: methods and results of the project SEpiAs. Epidemiological studies on population exposed to low-to-moderate arsenic concentration in drinking water","volume":"38","author":"Bustaffa","year":"2014","journal-title":"Epidemiol. Prev."},{"key":"10.1016\/j.etap.2018.07.012_bib0025","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.envres.2017.03.018","article-title":"Low-level inorganic arsenic exposure and neuropsychological functioning in American Indian elders","volume":"156","author":"Carroll","year":"2017","journal-title":"Environ. Res."},{"issue":"Suppl. 5","key":"10.1016\/j.etap.2018.07.012_bib0030","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1289\/ehp.02110s5883","article-title":"Pathology related to chronic arsenic exposure","volume":"110","author":"Centeno","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2018.07.012_bib0035","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1476-069X-14-12","article-title":"Preliminary analysis of in utero low-level arsenic exposure and fetal growth using biometric measurements extracted from fetal ultrasound reports","volume":"14","author":"Davis","year":"2015","journal-title":"Environ. Health"},{"issue":"7","key":"10.1016\/j.etap.2018.07.012_bib0040","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s10661-016-5405-1","article-title":"Autism spectrum disorder prevalence and associations with air concentrations of lead, mercury, and arsenic","volume":"188","author":"Dickerson","year":"2016","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.etap.2018.07.012_bib0045","first-page":"1","article-title":"A critical review of developmental exposure to particulate matter, autism spectrum disorder, and attention deficit hyperactivity disorder","volume":"20","author":"Fordyce","year":"2017","journal-title":"J. Environ. Sci. Health A Tox. Subst. Environ. Eng."},{"issue":"4","key":"10.1016\/j.etap.2018.07.012_bib0050","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/gwat.12251","article-title":"Palaeosol control of arsenic pollution: the Bengal Basin in West Bengal, India","volume":"53","author":"Ghosal","year":"2015","journal-title":"Ground Water"},{"issue":"4","key":"10.1016\/j.etap.2018.07.012_bib0055","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/WAD.0b013e3181d71bc7","article-title":"The arsenic exposure hypothesis for Alzheimer disease","volume":"24","author":"Gong","year":"2010","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"10.1016\/j.etap.2018.07.012_bib0060","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-4274(01)00534-3","article-title":"Chronic arsenic poisoning","volume":"128","author":"Hall","year":"2002","journal-title":"Toxicol. Lett."},{"issue":"1-2","key":"10.1016\/j.etap.2018.07.012_bib0065","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0165-5728(00)00320-9","article-title":"Anti-striatal antibodies in Tourette syndrome cause neuronal dysfunction","volume":"111","author":"Hallett","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.etap.2018.07.012_bib0070","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/426263","article-title":"Autism-like behavior and epigenetic changes associated with autism as consequences of in utero exposure to environmental pollutants in a mouse model","volume":"2015","author":"Hill","year":"2015","journal-title":"Behav. Neurol."},{"issue":"8","key":"10.1016\/j.etap.2018.07.012_bib0075","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s00702-016-1544-3","article-title":"Reduced functional connectivity to the frontal cortex during processing of social cues in autism spectrum disorder","volume":"123","author":"Hoffmann","year":"2016","journal-title":"J. Neural Transm. Vienna (Vienna)"},{"issue":"12","key":"10.1016\/j.etap.2018.07.012_bib0080","first-page":"14","article-title":"Investigation of health effects according to the exposure of low concentration arsenic contaminated ground water","author":"Hong","year":"2017","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"12","key":"10.1016\/j.etap.2018.07.012_bib0085","doi-asserted-by":"crossref","first-page":"12102","DOI":"10.1073\/pnas.96.21.12102","article-title":"An infection-based model of neurodevelopmental damage","volume":"96","author":"Hornig","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.etap.2018.07.012_bib0090","first-page":"112","article-title":"Exploration on teaching pattern of methodologyof pharmacological experiment","volume":"45","author":"Huang","year":"2017","journal-title":"Guangzhou Chem. Ind."},{"issue":"3","key":"10.1016\/j.etap.2018.07.012_bib0095","first-page":"112","article-title":"Exploration on teaching pattern of methodologyof pharmacological experiment","volume":"45","author":"Huang","year":"2017","journal-title":"Guangzhou Chemical Industry"},{"issue":"5","key":"10.1016\/j.etap.2018.07.012_bib0100","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.neuro.2012.07.003","article-title":"Changes in the synaptic structure of hippocampal neurons and impairment of spatial memory in a rat model caused by chronic arsenite exposure","volume":"33","author":"Jing","year":"2012","journal-title":"Neurotoxicology"},{"issue":"14","key":"10.1016\/j.etap.2018.07.012_bib0105","doi-asserted-by":"crossref","first-page":"23905","DOI":"10.18632\/oncotarget.14733","article-title":"Metabolism, toxicity and anticancer activities of arsenic compounds","volume":"8","author":"Khairul","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.etap.2018.07.012_bib0110","article-title":"Interaction between DRD2 and lead exposure on the cortical thickness of the frontal lobe in youth with attention-deficit\/hyperactivity disorder","author":"Kim","year":"2017","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.etap.2018.07.012_bib0115","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1177\/0306312716659372","article-title":"The maternal body as environment in autism science","volume":"46","author":"Lappe","year":"2016","journal-title":"Soc. Stud. Sci."},{"issue":"1","key":"10.1016\/j.etap.2018.07.012_bib0120","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s12011-017-1002-6","article-title":"Blood mercury, arsenic, cadmium, and lead in children with autism Spectrum disorder","volume":"181","author":"Li","year":"2017","journal-title":"Biol. Trace Elem. Res."},{"issue":"7","key":"10.1016\/j.etap.2018.07.012_bib0125","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1289\/ehp.10026","article-title":"Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms","volume":"115","author":"Lindberg","year":"2007","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.etap.2018.07.012_bib0130","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.toxlet.2008.10.029","article-title":"Effects of arsenic exposure from drinking water on spatial memory, ultra-structures and NMDAR gene expression of hippocampus in rats","volume":"184","author":"Luo","year":"2009","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.etap.2018.07.012_bib0135","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fnana.2015.00074","article-title":"Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides","volume":"9","author":"Maheu","year":"2015","journal-title":"Front. Neuroanat."},{"issue":"10","key":"10.1016\/j.etap.2018.07.012_bib0140","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1002\/cm.21300","article-title":"Microtubule and microtubule associated protein anomalies in psychiatric disease","volume":"73","author":"Marchisella","year":"2016","journal-title":"Cytoskeleton Hoboken (Hoboken)"},{"issue":"1","key":"10.1016\/j.etap.2018.07.012_bib0145","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/01.ede.0000147105.94041.e6","article-title":"Chronic arsenic exposure and adverse pregnancy outcomes in bangladesh","volume":"16","author":"Milton","year":"2005","journal-title":"Epidemiology"},{"key":"10.1016\/j.etap.2018.07.012_bib0150","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13229-017-0121-4","article-title":"Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses","volume":"8","author":"Modabbernia","year":"2017","journal-title":"Mol. Autism"},{"issue":"2","key":"10.1016\/j.etap.2018.07.012_bib0155","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/wdev.67","article-title":"Cytoskeleton in action: lissencephaly, a neuronal migration disorder","volume":"2","author":"Moon","year":"2013","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"issue":"3","key":"10.1016\/j.etap.2018.07.012_bib0160","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/tera.1420280311","article-title":"Arsenic-induced exencephaly in the mouse and associated lesions occurring during neurulation","volume":"28","author":"Morrissey","year":"1983","journal-title":"Teratology"},{"issue":"3","key":"10.1016\/j.etap.2018.07.012_bib0165","doi-asserted-by":"crossref","first-page":"861","DOI":"10.3390\/ijerph8030861","article-title":"Long-term low-level arsenic exposure is associated with poorer neuropsychological functioning: a Project FRONTIER study","volume":"8","author":"O\u2019Bryant","year":"2011","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"2","key":"10.1016\/j.etap.2018.07.012_bib0170","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0140-6736(79)91556-3","article-title":"Cell number and cell size: organ growth and development and the control of catch-up growth in rats","volume":"8","author":"Sands","year":"1979","journal-title":"Lancet"},{"issue":"20","key":"10.1016\/j.etap.2018.07.012_bib0175","doi-asserted-by":"crossref","first-page":"4843","DOI":"10.1242\/dev.129.20.4843","article-title":"Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts","volume":"129","author":"Shen","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.etap.2018.07.012_bib0180","doi-asserted-by":"crossref","first-page":"30601","DOI":"10.1038\/srep30601","article-title":"Hijacking microglial glutathione by inorganic arsenic impels bystander death of immature neurons through extracellular cystine\/glutamate imbalance","volume":"6","author":"Singh","year":"2016","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.etap.2018.07.012_bib0185","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s11011-016-9899-6","article-title":"Hair toxic and essential trace elements in children with autism spectrum disorder","volume":"32","author":"Skalny","year":"2017","journal-title":"Metab. Brain Dis."},{"issue":"4","key":"10.1016\/j.etap.2018.07.012_bib0190","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1007\/s10661-015-4418-5","article-title":"Mapping of arsenic pollution with reference to paddy cultivation in the middle Indo-Gangetic Plains","volume":"187","author":"Srivastava","year":"2015","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.etap.2018.07.012_bib0195","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3389\/fnmol.2017.00286","article-title":"Sodium arsenite-induced learning and memory impairment is associated with endoplasmic reticulum stress-mediated apoptosis in rat Hippocampus","volume":"10","author":"Sun","year":"2017","journal-title":"Front. Mol. Neurosci."},{"issue":"4","key":"10.1016\/j.etap.2018.07.012_bib0200","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/wdev.88","article-title":"Neocortical neurogenesis and neuronal migration","volume":"2","author":"Tan","year":"2013","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"issue":"4","key":"10.1016\/j.etap.2018.07.012_bib0205","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1176\/appi.ajp.159.4.657","article-title":"An animal model of Tourette\u2019s syndrome","volume":"159","author":"Taylor","year":"2002","journal-title":"Am. J. Psychiatry"},{"issue":"4","key":"10.1016\/j.etap.2018.07.012_bib0210","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.aogh.2014.09.005","article-title":"The developmental neurotoxicity of arsenic: cognitive and behavioral consequences of early life exposure","volume":"80","author":"Tolins","year":"2014","journal-title":"Ann. Glob. Health"},{"key":"10.1016\/j.etap.2018.07.012_bib0215","doi-asserted-by":"crossref","first-page":"5480","DOI":"10.12659\/MSM.907160","article-title":"Notch1 signaling activation contributes to adult hippocampal neurogenesis following traumatic brain injury","volume":"23","author":"Tu","year":"2017","journal-title":"Med. Sci. Monit."},{"issue":"1","key":"10.1016\/j.etap.2018.07.012_bib0220","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.conb.2009.12.003","article-title":"Neuronal migration mechanisms in development and disease","volume":"20","author":"Valiente","year":"2010","journal-title":"Curr. Opin. Neurobiol."},{"issue":"2","key":"10.1016\/j.etap.2018.07.012_bib0225","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1038\/nprot.2006.116","article-title":"Morris water maze: procedures for assessing spatial and related forms of learning and memory","volume":"1","author":"Vorhees","year":"2006","journal-title":"Nat. Protoc."},{"issue":"6","key":"10.1016\/j.etap.2018.07.012_bib0230","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00204-009-0403-5","article-title":"Transplacental and early life exposure to inorganic arsenic affected development and behavior in offspring rats","volume":"83","author":"Xi","year":"2009","journal-title":"Arch. Toxicol."},{"issue":"5","key":"10.1016\/j.etap.2018.07.012_bib0235","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s10571-011-9670-9","article-title":"Time course of postnatal distribution of doublecortin immunoreactive developing\/maturing neurons in the somatosensory cortex and hippocampal CA1 region of C57BL\/6 mice","volume":"31","author":"Yoo","year":"2011","journal-title":"Cell Mol. Neurobiol."},{"issue":"7","key":"10.1016\/j.etap.2018.07.012_bib0240","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1631\/jzus.B1400003","article-title":"Diversity change of microbial communities responding to zinc and arsenic pollution in a river of northeastern China","volume":"15","author":"Zhao","year":"2014","journal-title":"J. Zhejiang Univ. Sci. B"},{"issue":"1","key":"10.1016\/j.etap.2018.07.012_bib0245","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/1097-0029(20010101)52:1<89::AID-JEMT11>3.0.CO;2-2","article-title":"Toxicology of choroid plexus: special reference to metal-induced neurotoxicities","volume":"52","author":"Zheng","year":"2001","journal-title":"Microsc. Res. Tech."},{"issue":"3","key":"10.1016\/j.etap.2018.07.012_bib0250","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.etap.2015.08.026","article-title":"Inhibitory effect of arsenic trioxide on neuronal migration in vitro and its potential molecular mechanism","volume":"40","author":"Zhou","year":"2015","journal-title":"Environ. Toxicol. Pharmacol."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668918301674?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668918301674?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T03:53:30Z","timestamp":1661658810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668918301674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":50,"alternative-id":["S1382668918301674"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2018.07.012","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Postnatal low-concentration arsenic exposure induces autism-like behavior and affects frontal cortex neurogenesis in rats","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2018.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}