{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:17:15Z","timestamp":1790709435656,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"\u201cNational Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81770020"],"award-info":[{"award-number":["81770020"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.etap.2019.03.013","type":"journal-article","created":{"date-parts":[[2019,3,11]],"date-time":"2019-03-11T22:24:40Z","timestamp":1552343080000},"page":"155-163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Fine particulate matter (PM2.5) enhances airway hyperresponsiveness (AHR) by inducing necroptosis in BALB\/c mice"],"prefix":"10.1016","volume":"68","author":[{"given":"Yunxia","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiran","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuna","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xixin","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2019.03.013_bib0005","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.envpol.2017.11.093","article-title":"Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes","volume":"234","author":"Bhargava","year":"2018","journal-title":"Environ Pollut"},{"issue":"11","key":"10.1016\/j.etap.2019.03.013_bib0010","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1164\/rccm.201702-0421OC","article-title":"Prenatal Nitrate Exposure and Childhood Asthma. Influence of Maternal Prenatal Stress and Fetal Sex","volume":"196","author":"Bose","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.etap.2019.03.013_bib0015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/15287394.2016.1222920","article-title":"Fine particulate matter (PM2.5) enhances allergic sensitization in BALB\/c mice","volume":"80","author":"Castaneda","year":"2017","journal-title":"J Toxicol Environ Health A"},{"issue":"18","key":"10.1016\/j.etap.2019.03.013_bib0020","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1080\/15287394.2014.922387","article-title":"Fine particulate air pollution and hospital admissions for asthma: a case-crossover study in Taipei","volume":"77","author":"Cheng","year":"2014","journal-title":"J Toxicol Environ Health A"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0025","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s12931-017-0610-1","article-title":"Forced expiration measurements in mouse models of obstructive and restrictive lung diseases","volume":"18","author":"Devos","year":"2017","journal-title":"Respir Res"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0030","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/cdd.2011.96","article-title":"Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012","volume":"19","author":"Galluzzi","year":"2012","journal-title":"Cell Death Differ"},{"issue":"19","key":"10.1016\/j.etap.2019.03.013_bib0035","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1080\/15384101.2017.1371889","article-title":"Biological events and molecular signaling following MLKL activation during necroptosis","volume":"16","author":"Gong","year":"2017","journal-title":"Cell Cycle"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0040","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/EDE.0b013e318276c1ea","article-title":"Exposure to air pollution from traffic and childhood asthma until 12 years of age","volume":"24","author":"Gruzieva","year":"2013","journal-title":"Epidemiology"},{"key":"10.1016\/j.etap.2019.03.013_bib0045","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12989-016-0114-z","article-title":"Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects","volume":"13","author":"Hosseini","year":"2016","journal-title":"Part Fibre Toxicol"},{"issue":"2","key":"10.1016\/j.etap.2019.03.013_bib0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0173158","article-title":"The effect of size-segregated ambient particulate matter on Th1\/Th2-like immune responses in mice","volume":"12","author":"Huang","year":"2017","journal-title":"PLoS One"},{"issue":"17","key":"10.1016\/j.etap.2019.03.013_bib0055","doi-asserted-by":"crossref","first-page":"15012","DOI":"10.1007\/s11356-017-9121-3","article-title":"Effects of fine particulate matter and its constituents on emergency room visits for asthma in southern Taiwan during 2008-2010: a population-based study","volume":"24","author":"Hwang","year":"2017","journal-title":"Environ Sci Pollut Res Int"},{"issue":"6","key":"10.1016\/j.etap.2019.03.013_bib0060","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.molcel.2017.02.024","article-title":"An Inflammatory Perspective on Necroptosis","volume":"65","author":"Kearney","year":"2017","journal-title":"Mol Cell"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0065","doi-asserted-by":"crossref","first-page":"6","DOI":"10.15430\/JCP.2017.22.1.6","article-title":"Predictive and Prognostic Biomarkers of Respiratory Diseases due to Particulate Matter Exposure","volume":"22","author":"Kim","year":"2017","journal-title":"Journal of Cancer Prevention"},{"issue":"6","key":"10.1016\/j.etap.2019.03.013_bib0070","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph13060579","article-title":"The Effect of Seasonal Variations in Airborne Particulate Matter on Asthma-Related Airway Inflammation in Mice","volume":"13","author":"Kurai","year":"2016","journal-title":"Int J Environ Res Public Health"},{"issue":"12","key":"10.1016\/j.etap.2019.03.013_bib0075","doi-asserted-by":"crossref","first-page":"11559","DOI":"10.1007\/s11356-017-8575-7","article-title":"Burden of disease attributed to ambient PM2.5 and PM10 exposure in 190 cities in China","volume":"24","author":"Maji","year":"2017","journal-title":"Environ Sci Pollut Res Int"},{"key":"10.1016\/j.etap.2019.03.013_bib0080","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.chemosphere.2017.08.076","article-title":"Cell death pathways of particulate matter toxicity","volume":"188","author":"Peixoto","year":"2017","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.etap.2019.03.013_bib0085","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/icb.2016.125","article-title":"Insane in the membrane: a structural perspective of MLKL function in necroptosis","volume":"95","author":"Petrie","year":"2017","journal-title":"Immunol Cell Biol"},{"issue":"4","key":"10.1016\/j.etap.2019.03.013_bib0090","doi-asserted-by":"crossref","first-page":"L3","DOI":"10.1152\/ajplung.00174.2015","article-title":"Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice","volume":"310","author":"Pouwels","year":"2016","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0095","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jaci.2014.07.046","article-title":"Identification of novel immune phenotypes for allergic and nonallergic childhood asthma","volume":"135","author":"Raedler","year":"2015","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"10.1016\/j.etap.2019.03.013_bib0100","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/978-981-10-5657-4_2","article-title":"Characteristics of Major Air Pollutants in China","volume":"1017","author":"Ren","year":"2017","journal-title":"Adv Exp Med Biol"},{"issue":"3","key":"10.1016\/j.etap.2019.03.013_bib0105","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19030684","article-title":"Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss","volume":"19","author":"Wicki","year":"2018","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0110","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s12940-016-0196-y","article-title":"Pediatric emergency department visits and ambient Air pollution in the U.S. State of Georgia: a case-crossover study","volume":"15","author":"Xiao","year":"2016","journal-title":"Environ Health"},{"key":"10.1016\/j.etap.2019.03.013_bib0115","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/812469","article-title":"Quantifying the sources of the severe haze over the Southern Hebei using the CMAQ model","author":"Yang","year":"2013","journal-title":"ScientificWorldJournal"},{"issue":"8","key":"10.1016\/j.etap.2019.03.013_bib0120","first-page":"785","article-title":"Ambient PM2.5 exposure exacerbates severity of allergic asthma in previously sensitized mice","volume":"52","author":"Zhang","year":"2015","journal-title":"J Asthma"},{"issue":"5","key":"10.1016\/j.etap.2019.03.013_bib0125","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/s41419-018-0524-y","article-title":"Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression","volume":"9","author":"Zhu","year":"2018","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.etap.2019.03.013_bib0130","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.redox.2018.02.019","article-title":"Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload\/XO\/ROS\/mPTP pathway","volume":"16","author":"Zhu","year":"2018","journal-title":"Redox Biol"},{"issue":"1","key":"10.1016\/j.etap.2019.03.013_bib0135","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.anai.2014.04.013","article-title":"Differentiating asthma phenotypes in young adults through polyclonal cytokine profiles","volume":"113","author":"Zoratti","year":"2014","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668919300341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668919300341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T09:42:06Z","timestamp":1761298926000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668919300341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":27,"alternative-id":["S1382668919300341"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2019.03.013","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fine particulate matter (PM2.5) enhances airway hyperresponsiveness (AHR) by inducing necroptosis in BALB\/c mice","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2019.03.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}