{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T08:09:37Z","timestamp":1778314177555,"version":"3.51.4"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.etap.2022.103902","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T16:28:35Z","timestamp":1654878515000},"page":"103902","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Effects of UGT2B7 rs7662029 and rs7439366 polymorphisms on sublingual buprenorphine metabolism in heroin addicts: An improved PCR-RFLP assay for the detection of rs7662029 polymorphism"],"prefix":"10.1016","volume":"94","author":[{"given":"Dilek","family":"Kaya-Aky\u00fczl\u00fc","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selin","family":"\u00d6zkan-Kotilo\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ceylan","family":"Bal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eafak","family":"Yal\u00e7\u0131n-\u015eahiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gamze","family":"Avc\u0131o\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Dan\u0131\u015fman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2022.103902_bib1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0090-9556(24)15092-1","article-title":"3\u2019-azido-3\u2019-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)","volume":"28","author":"Barbier","year":"2000","journal-title":"Drug. Metab. Dispos."},{"issue":"7 Suppl","key":"10.1016\/j.etap.2022.103902_bib2","first-page":"673","article-title":"Functional characterization of the UGT1A9183Gly and UGT2B7268Tyr polymorphic variants","volume":"64","author":"Bendaly","year":"2004","journal-title":"Proc. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.etap.2022.103902_bib3","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1124\/dmd.106.010553","article-title":"Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acid","volume":"34","author":"Bernard","year":"2006","journal-title":"Drug. Metab. Dispos."},{"issue":"8","key":"10.1016\/j.etap.2022.103902_bib4","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/00008571-200011000-00002","article-title":"Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance","volume":"10","author":"Bhasker","year":"2000","journal-title":"Pharmacogenetics"},{"issue":"7","key":"10.1016\/j.etap.2022.103902_bib5","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1111\/papr.12343","article-title":"Influence of UGT2B7, CYP3A4, and OPRM1 gene polymorphisms on transdermal buprenorphine pain control in patients with critical lower limb ischemia awaiting revascularization","volume":"16","author":"Blanco","year":"2016","journal-title":"Pain Pract."},{"key":"10.1016\/j.etap.2022.103902_bib6","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1158\/0008-5472.CAN-08-3708","article-title":"Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites","volume":"69","author":"Blevins-Primeau","year":"2009","journal-title":"Cancer Res."},{"issue":"6","key":"10.1016\/j.etap.2022.103902_bib7","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1097\/ALN.0b013e318238fea0","article-title":"Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active","volume":"115","author":"Brown","year":"2011","journal-title":"Anesthesiology"},{"issue":"3","key":"10.1016\/j.etap.2022.103902_bib8","doi-asserted-by":"crossref","first-page":"209","DOI":"10.5455\/bcp.20150404070711","article-title":"Reliability and validity of the Turkish version of the clinical opiate withdrawal scale (COWS)","volume":"25","author":"Canan","year":"2015","journal-title":"Bull. Clin. Psychopharmacol."},{"issue":"13\u201315","key":"10.1016\/j.etap.2022.103902_bib9","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1080\/15287394.2017.1286922","article-title":"Association of UGT2B7, UGT1A9, ABCG2, and IL23R polymorphisms with rejection risk in kidney transplant patients","volume":"80","author":"Cili\u00e3o","year":"2017","journal-title":"J. Toxicol. Environ. Health A"},{"issue":"3","key":"10.1016\/j.etap.2022.103902_bib10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/tpj.2013.30","article-title":"Genetic variation in OPRD1 and the response to treatment for opioid dependence with buprenorphine in European-American females","volume":"14","author":"Clarke","year":"2014","journal-title":"Pharmacogenom. J."},{"key":"10.1016\/j.etap.2022.103902_bib11","first-page":"73","article-title":"The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)","volume":"26","author":"Coffman","year":"1998","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.etap.2022.103902_bib12","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1124\/dmd.31.9.1125","article-title":"Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism","volume":"31","author":"Court","year":"2003","journal-title":"Drug Metab. Dispos."},{"issue":"4","key":"10.1016\/j.etap.2022.103902_bib13","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s40263-018-0513-9","article-title":"Pharmacogenetics of opioid use disorder treatment","volume":"32","author":"Crist","year":"2018","journal-title":"CNS Drugs"},{"issue":"12","key":"10.1016\/j.etap.2022.103902_bib14","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s40265-018-0953-z","article-title":"Treating chronic pain: an overview of clinical studies centered on the buprenorphine option","volume":"78","author":"Davis","year":"2018","journal-title":"Drugs"},{"key":"10.1016\/j.etap.2022.103902_bib15","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/FPC.0b013e32801430f8","article-title":"Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients","volume":"17","author":"Djebli","year":"2007","journal-title":"Pharm. Genom."},{"key":"10.1016\/j.etap.2022.103902_bib16","doi-asserted-by":"crossref","first-page":"4107","DOI":"10.12659\/MSM.897626","article-title":"Association of UGT2B7 and UGT1A4 polymorphisms with serum concentration of antiepileptic drugs in children","volume":"22","author":"Du","year":"2016","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.etap.2022.103902_bib17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.clpt.2003.10.006","article-title":"A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity","volume":"75","author":"Duguay","year":"2004","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.etap.2022.103902_bib18","first-page":"8","article-title":"Pharmacogenomics-guided policy in opioid use disorder (OUD) management: an ethnically-diverse case-based approach","volume":"6","author":"Ettienne","year":"2017","journal-title":"Addict. Behav. Rep."},{"issue":"6","key":"10.1016\/j.etap.2022.103902_bib19","first-page":"674","article-title":"Pharmacogenomics and opioid use disorder: clinical decision support in an African American Cohort","volume":"111","author":"Ettienne","year":"2019","journal-title":"J. Natl. Med. Assoc."},{"key":"10.1016\/j.etap.2022.103902_bib20","first-page":"70","article-title":"Reliability and validity of the Penn Alcohol Craving Scale (PACS) Revised Version for substance craving in male substance dependent inpatients","volume":"22","author":"Evren","year":"2011","journal-title":"Turk. J. Psychiatry"},{"issue":"9","key":"10.1016\/j.etap.2022.103902_bib21","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1038\/npp.2016.38","article-title":"Antidepressant-like effects of buprenorphine are mediated by kappa opioid receptors","volume":"41","author":"Falcon","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"10.1016\/j.etap.2022.103902_bib22","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1002\/jcla.21968","article-title":"An improved PCR-RFLP assay for the detection of a polymorphism rs2289487 of PLIN1 gene","volume":"30","author":"Feng","year":"2016","journal-title":"J. Clin. Lab Anal."},{"key":"10.1016\/j.etap.2022.103902_bib23","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.forsciint.2018.04.038","article-title":"Toxicological investigation in blood samples from suspected impaired driving cases in the Milan area: possible loss of evidence due to late blood sampling","volume":"288","author":"Ferrari","year":"2018","journal-title":"Forensic Sci. Int."},{"issue":"12","key":"10.1016\/j.etap.2022.103902_bib24","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1007\/s00228-018-2548-8","article-title":"Voriconazole greatly increases the exposure to oral buprenorphine","volume":"74","author":"Fihlman","year":"2018","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1016\/j.etap.2022.103902_bib25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0960-0760(99)00088-6","article-title":"Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7","volume":"70","author":"Gall","year":"1999","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.etap.2022.103902_bib26","first-page":"320","article-title":"Mycophenolic acid pharmacogenomics in kidney transplantation","volume":"4","author":"Genvigir","year":"2020","journal-title":"J. Transl. Genet. Genom."},{"issue":"6","key":"10.1016\/j.etap.2022.103902_bib27","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1210\/en.2002-0052","article-title":"Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites","volume":"144","author":"Girard","year":"2003","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.etap.2022.103902_bib28","doi-asserted-by":"crossref","first-page":"536","DOI":"10.2133\/dmpk.DMPK-11-NT-144","article-title":"Effects of UGT1A6, UGT2B7, and CYP2C9 genotypes on plasma concentrations of valproic acid in Chinese children with epilepsy","volume":"27","author":"Guo","year":"2012","journal-title":"Drug Metab. Pharmacokinet."},{"key":"10.1016\/j.etap.2022.103902_bib29","first-page":"3","article-title":"Reliability and validity of Beck Depression Inventory among university students","volume":"7","author":"Hisli","year":"1989","journal-title":"Turk. Psikol. Derg."},{"key":"10.1016\/j.etap.2022.103902_bib30","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/sj.tpj.6500139","article-title":"Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients","volume":"3","author":"Holthe","year":"2003","journal-title":"Pharmacogenom. J."},{"key":"10.1016\/j.etap.2022.103902_bib31","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1124\/dmd.113.056630","article-title":"Polymorphisms, and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter","volume":"42","author":"Hu","year":"2014","journal-title":"Drug. Metab. Dispos."},{"issue":"10","key":"10.1016\/j.etap.2022.103902_bib32","doi-asserted-by":"crossref","first-page":"eaax9140","DOI":"10.1126\/sciadv.aax9140","article-title":"Current status of opioid addiction treatment and related preclinical research","volume":"5","author":"Kreek","year":"2019","journal-title":"Sci. Adv."},{"issue":"11","key":"10.1016\/j.etap.2022.103902_bib33","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000019444","article-title":"The correlation between UDP-glucuronosyltransferase polymorphisms and environmental endocrine disruptors levels in polycystic ovary syndrome patients","volume":"99","author":"Luo","year":"2020","journal-title":"Medicine"},{"issue":"8","key":"10.1016\/j.etap.2022.103902_bib34","first-page":"766","article-title":"Effect of UGT2B7 genetic variants on serum valproic acid concentration","volume":"38","author":"Ma","year":"2013","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"issue":"3","key":"10.1016\/j.etap.2022.103902_bib35","doi-asserted-by":"crossref","first-page":"R57","DOI":"10.1186\/bcr2894","article-title":"Impact of UGT2B7 His268Tyr polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer","volume":"13","author":"Parmar","year":"2011","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.etap.2022.103902_bib36","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1111\/j.1365-2125.2007.02923.x","article-title":"Limited influence of UGT1A1*28 and no effect of UGT2B7*2 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes","volume":"64","author":"Peterkin","year":"2007","journal-title":"Br. J. Clin. Pharmacol."},{"issue":"7","key":"10.1016\/j.etap.2022.103902_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0132269","article-title":"Impacts of the glucuronidase genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on tamoxifen metabolism in breast cancer patients","volume":"10","author":"Romero-Lorca","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.etap.2022.103902_bib38","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1124\/dmd.109.029546","article-title":"Contribution of the Different UDP-glucuronosyltransferase (UGT) Isoforms to buprenorphine and norbuprenorphine metabolism and relationship with the Main UGT polymorphisms in a bank of human liver microsomes","volume":"38","author":"Rouguieg","year":"2010","journal-title":"Drug Metab. Dispos."},{"issue":"1","key":"10.1016\/j.etap.2022.103902_bib39","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/papr.12152","article-title":"Influence of uridine diphosphate-glucuronyltransferase 2B7 (UGT2B7) variants on postoperative buprenorphine analgesia","volume":"15","author":"Sastre","year":"2015","journal-title":"Pain. Pract."},{"key":"10.1016\/j.etap.2022.103902_bib40","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/S0009-9236(03)00053-5","article-title":"A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine","volume":"73","author":"Sawyer","year":"2003","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.etap.2022.103902_bib41","first-page":"263","article-title":"A review of the pharmacogenomics of buprenorphine for the treatment of opioid use disorder","volume":"4","author":"Segui","year":"2020","journal-title":"J. Transl. Genet. Genom."},{"issue":"3","key":"10.1016\/j.etap.2022.103902_bib42","doi-asserted-by":"crossref","first-page":"104","DOI":"10.18017\/iuitfd.363585","article-title":"Effect of uridine diphosphate-glucuronosyltransferase polymorphisms on the plasma concentrations of mycophenolic acid in turkish renal transplant patients","volume":"80","author":"Senturk-Ciftci","year":"2017","journal-title":"J. Istanb. Fac. Med."},{"issue":"4","key":"10.1016\/j.etap.2022.103902_bib43","first-page":"4513","article-title":"Effects of UGT1A3, UGT1A6, and UGT2B7 genetic polymorphisms on plasma concentration of valproic acid in south Chinese epilepsy patients","volume":"9","author":"Shen","year":"2016","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"1","key":"10.1016\/j.etap.2022.103902_bib44","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41572-019-0137-5","article-title":"Opioid use disorder","volume":"6","author":"Strang","year":"2020","journal-title":"Nat. Rev. Dis. Prim."},{"issue":"1","key":"10.1016\/j.etap.2022.103902_bib45","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1158\/0008-5472.CAN-05-2857","article-title":"Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone","volume":"66","author":"Thibaudeau","year":"2006","journal-title":"Cancer Res."},{"issue":"8","key":"10.1016\/j.etap.2022.103902_bib46","doi-asserted-by":"crossref","first-page":"879","DOI":"10.2217\/pgs.12.69","article-title":"UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients","volume":"13","author":"Tian","year":"2012","journal-title":"Pharmacogenomics"},{"issue":"2","key":"10.1016\/j.etap.2022.103902_bib47","first-page":"163","article-title":"Turkish version of the Beck Anxiety Inventory: psychometric properties","volume":"12","author":"Ulusoy","year":"1998","journal-title":"J. Cogn. Psychother."},{"issue":"11","key":"10.1016\/j.etap.2022.103902_bib48","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.bcp.2011.08.004","article-title":"Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen","volume":"82","author":"Wang","year":"2011","journal-title":"Biochem. Pharmacol."},{"issue":"3","key":"10.1016\/j.etap.2022.103902_bib49","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1158\/0008-5472.CAN-03-3219","article-title":"Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes","volume":"64","author":"Wiener","year":"2004","journal-title":"Cancer Res."},{"issue":"8","key":"10.1016\/j.etap.2022.103902_bib50","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1038\/aps.2016.157","article-title":"The regioselective glucuronidation of morphine by dimerized human UGT2B7, 1A1, 1A9 and their allelic variants","volume":"38","author":"Yang","year":"2017","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.etap.2022.103902_bib51","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1186\/1475-2875-13-478","article-title":"The effect of UGTs polymorphism on the auto-induction phase II metabolism-mediated pharmacokinetics of dihydroartemisinin in healthy Chinese subjects after oral administration of a fixed combination of dihydroartemisinin-piperaquine","volume":"13","author":"Zang","year":"2014","journal-title":"Malar. J."},{"issue":"2","key":"10.1016\/j.etap.2022.103902_bib52","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.braindev.2017.09.004","article-title":"Correlations between UGT2B7\u22172 gene polymorphisms and plasma concentrations of carbamazepine and valproic acid in epilepsy patients","volume":"40","author":"Zhang","year":"2018","journal-title":"Brain Dev."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668922000953?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668922000953?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T09:50:11Z","timestamp":1761299411000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668922000953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":52,"alternative-id":["S1382668922000953"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2022.103902","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of UGT2B7 rs7662029 and rs7439366 polymorphisms on sublingual buprenorphine metabolism in heroin addicts: An improved PCR-RFLP assay for the detection of rs7662029 polymorphism","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2022.103902","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103902"}}