{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T03:18:45Z","timestamp":1770347925563,"version":"3.49.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010426","name":"University Grants Commission Department of Atomic Energy Consortium for Scientific Research","doi-asserted-by":"publisher","award":["UGC-DAE-CSR-KC\/CRS\/2021\\u201322\/02\/520"],"award-info":[{"award-number":["UGC-DAE-CSR-KC\/CRS\/2021\\u201322\/02\/520"]}],"id":[{"id":"10.13039\/501100010426","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001410","name":"Council of Scientific and Industrial Research Human Resource Development Group","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","award":["09\/202(0102)\/2019-EMR-I"],"award-info":[{"award-number":["09\/202(0102)\/2019-EMR-I"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"India Ministry of Science & Technology Department of Biotechnology","doi-asserted-by":"publisher","award":["BT\/PR28560\/AAQ\/3\/919\/2018"],"award-info":[{"award-number":["BT\/PR28560\/AAQ\/3\/919\/2018"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.etap.2025.104640","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T03:47:53Z","timestamp":1737085673000},"page":"104640","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Mixture effects of arsenic and chromium on erythrocytic nuclear abnormalities and expression of DNA repair, tumor suppressor and apoptotic genes in liver of zebrafish"],"prefix":"10.1016","volume":"114","author":[{"given":"Sreejata","family":"Kamila","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koushik Kumar","family":"Dey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanmoy","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ansuman","family":"Chattopadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.etap.2025.104640_bib1","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.etp.2013.01.003","article-title":"Arsenic induced toxicity and histopathological changes in gill and liver tissue of freshwater fish, tilapia (Oreochromis mossambicus)","volume":"65","author":"Ahmed","year":"2013","journal-title":"Exp. Toxicol. Pathol."},{"issue":"3","key":"10.1016\/j.etap.2025.104640_bib2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.3390\/cancers13030447","article-title":"K3326X and other C-terminal BRCA2 variants implicated in hereditary cancer syndromes: a review","volume":"13","author":"Baughan","year":"2021","journal-title":"Cancers"},{"key":"10.1016\/j.etap.2025.104640_bib3","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.envres.2018.01.002","article-title":"Epigenetic alteration of mismatch repair genes in the population chronically exposed to arsenic in West Bengal, India","volume":"163","author":"Bhattacharjee","year":"2018","journal-title":"Environ. Res."},{"issue":"1","key":"10.1016\/j.etap.2025.104640_bib4","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/mutage\/geq073","article-title":"Micronucleus assay in aquatic animals","volume":"26","author":"Bolognesi","year":"2011","journal-title":"Mutagenesis"},{"issue":"3","key":"10.1016\/j.etap.2025.104640_bib5","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.3390\/cancers6031597","article-title":"DNA mismatch repair and oxidative DNA damage: implications for cancer biology and treatment","volume":"6","author":"Bridge","year":"2014","journal-title":"Cancers"},{"key":"10.1016\/j.etap.2025.104640_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102321","article-title":"Arsenic retention in erythrocytes and excessive erythrophagocytosis is related to low selenium status by impaired redox homeostasis","volume":"52","author":"Cai","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.etap.2025.104640_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118019","article-title":"Micronucleus test and nuclear abnormality assay in zebrafish (Danio rerio): Past, present, and future trends","volume":"290","author":"Canedo","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.etap.2025.104640_bib8","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.aquatox.2013.10.006","article-title":"Arsenic exposure alters expression of cell cycle and lipid metabolism genes in the liver of adult zebrafish (Danio rerio)","volume":"153","author":"Carlson","year":"2014","journal-title":"Aquat. Toxicol."},{"issue":"2","key":"10.1016\/j.etap.2025.104640_bib9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3390\/jcs7020059","article-title":"Biochar Derived from Rice by-Products for Arsenic and Chromium Removal by Adsorption: A Review","volume":"7","author":"Chatzimichailidou","year":"2023","journal-title":"J. Compos. Sci."},{"issue":"3","key":"10.1016\/j.etap.2025.104640_bib10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.molcel.2010.01.025","article-title":"The BCL-2 family reunion","volume":"37","author":"Chipuk","year":"2010","journal-title":"Mol. Cell"},{"issue":"3","key":"10.1016\/j.etap.2025.104640_bib11","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1080\/10590501.2010.504980","article-title":"Review of chromium (VI) apoptosis, cell-cycle-arrest, and carcinogenesis","volume":"28","author":"Chiu","year":"2010","journal-title":"J. Environ. Sci. Health, Part C."},{"issue":"2","key":"10.1016\/j.etap.2025.104640_bib12","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1089\/zeb.2017.1507","article-title":"Comparison of the base excision repair activity in liver cell models of zebrafish (Danio rerio)","volume":"15","author":"Costa","year":"2018","journal-title":"Zebrafish"},{"issue":"1","key":"10.1016\/j.etap.2025.104640_bib13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.aquatox.2009.03.001","article-title":"Hexabromocyclododecane-induced developmental toxicity and apoptosis in zebrafish embryos","volume":"93","author":"Deng","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2025.104640_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2024.104396","article-title":"Lead induced genotoxicity and hepatotoxicity in zebrafish (Danio rerio) at environmentally relevant concentration: Nrf2-Keap1 regulated stress response and expression of biomarker genes","author":"Dey","year":"2024","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.etap.2025.104640_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11270-016-2779-1","article-title":"Genotoxic effect and carcinogenic potential of a mixture of as and cd in zebrafish at permissible maximum contamination levels for drinking water","volume":"227","author":"Doganlar","year":"2016","journal-title":"Water, Air, Soil Pollut."},{"issue":"8","key":"10.1016\/j.etap.2025.104640_bib16","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.biocel.2011.04.015","article-title":"Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafish","volume":"43","author":"Duan","year":"2011","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1-3","key":"10.1016\/j.etap.2025.104640_bib17","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0048-9697(03)00056-1","article-title":"Natural contamination with arsenic and other trace elements in ground waters of Argentine Pampean Plain","volume":"309","author":"Far\u00edas","year":"2003","journal-title":"Sci. Total Environ."},{"issue":"23","key":"10.1016\/j.etap.2025.104640_bib18","doi-asserted-by":"crossref","first-page":"5396","DOI":"10.1021\/bi900253d","article-title":"Base excision repair in early zebrafish development: evidence for DNA polymerase switching and standby AP endonuclease activity","volume":"48","author":"Fortier","year":"2009","journal-title":"Biochemistry"},{"key":"10.1016\/j.etap.2025.104640_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13205-018-1366-0","article-title":"Lrcasp9 shares similarity in structural motifs with human caspase-9 and is activated following bacterial infection and anti-viral vaccination","volume":"8","author":"Giri","year":"2018","journal-title":"3 Biotech"},{"key":"10.1016\/j.etap.2025.104640_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138067","article-title":"Potential arsenic\u2013chromium\u2013lead Co-contamination in the hilly terrain of Arunachal Pradesh, north-eastern India: Genesis and health perspective","volume":"323","author":"Goswami","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2025.104640_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.125967","article-title":"Genotoxicity induced by hexavalent chromium leading to eryptosis in Ctenopharyngodon idellus","volume":"247","author":"Handa","year":"2020","journal-title":"Chemosphere"},{"issue":"7446","key":"10.1016\/j.etap.2025.104640_bib22","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature12111","article-title":"The zebrafish reference genome sequence and its relationship to the human genome","volume":"496","author":"Howe","year":"2013","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.etap.2025.104640_bib23","doi-asserted-by":"crossref","first-page":"0808","DOI":"10.1007\/s00128-002-0132-4","article-title":"Leaching of arsenic, chromium, and copper in a contaminated soil at a wood preserving site","volume":"69","author":"Jang","year":"2002","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.etap.2025.104640_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.171221","article-title":"Arsenic and chromium induced hepatotoxicity in zebrafish (Danio rerio) at environmentally relevant concentrations: Mixture effects and involvement of Nrf2-Keap1-ARE pathway","author":"Kamila","year":"2024","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.etap.2025.104640_bib25","first-page":"69","article-title":"Is Bax\/Bcl-2 ratio considered as a prognostic marker with age and tumor location in colorectal cancer?","volume":"19","author":"Khodapasand","year":"2015","journal-title":"Iran. Biomed. J."},{"key":"10.1016\/j.etap.2025.104640_bib26","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.aquatox.2013.03.005","article-title":"DNA repair activity in fish and interest in ecotoxicology: A review","volume":"134","author":"Kienzler","year":"2013","journal-title":"Aquat. Toxicol."},{"issue":"5","key":"10.1016\/j.etap.2025.104640_bib27","article-title":"Determination of arsenic induced nuclear abnormalities in peripheral blood erythrocytes of carps using micronucleus test","volume":"26","author":"Kousar","year":"2016","journal-title":"JAPS: J. Anim. Plant Sci."},{"key":"10.1016\/j.etap.2025.104640_bib28","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jhazmat.2015.09.022","article-title":"In Vivo toxicological assessment of biologically synthesized silver nanoparticles in adult Zebrafish (Danio rerio)","volume":"301","author":"Krishnaraj","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.etap.2025.104640_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124364","article-title":"Global evaluation of heavy metal content in surface water bodies: A meta-analysis using heavy metal pollution indices and multivariate statistical analyses","volume":"236","author":"Kumar","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2025.104640_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2017.08.029","article-title":"Identification of apoptosis-related genes Bcl2 and Bax from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to waterborne and dietborne zinc exposure","volume":"633","author":"Li","year":"2017","journal-title":"Gene"},{"issue":"1","key":"10.1016\/j.etap.2025.104640_bib31","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/tox.20305","article-title":"Molecular multi-effect screening of environmental pollutants using the MolDarT","volume":"23","author":"Liedtke","year":"2008","journal-title":"Environ. Toxicol."},{"issue":"2","key":"10.1016\/j.etap.2025.104640_bib32","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.canlet.2013.12.025","article-title":"Tumor suppressor p53 and its mutants in cancer metabolism","volume":"356","author":"Liu","year":"2015","journal-title":"Cancer Lett."},{"issue":"4","key":"10.1016\/j.etap.2025.104640_bib33","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"methods"},{"key":"10.1016\/j.etap.2025.104640_bib34","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.toxrep.2022.03.037","article-title":"Epigenetic mechanisms in metal carcinogenesis","volume":"9","author":"Mani\u0107","year":"2022","journal-title":"Toxicol. Rep."},{"issue":"7","key":"10.1016\/j.etap.2025.104640_bib35","doi-asserted-by":"crossref","first-page":"7166","DOI":"10.1007\/s11356-019-07408-9","article-title":"Chlorpyrifos levels within permitted limits induce nuclear abnormalities and DNA damage in the erythrocytes of the common carp","volume":"27","author":"Mitkovska","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"1","key":"10.1016\/j.etap.2025.104640_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13237-022-00391-6","article-title":"Environmentally relevant fluoride alters nuclear integrity in erythrocytes and induces DNA damage in hepatocytes of zebrafish","volume":"66","author":"Mondal","year":"2023","journal-title":"Nucleus"},{"key":"10.1016\/j.etap.2025.104640_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128678","article-title":"Combined effect of arsenic and fluoride at environmentally relevant concentrations in zebrafish (Danio rerio) brain: Alterations in stress marker and apoptotic gene expression","volume":"269","author":"Mondal","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2025.104640_bib38","doi-asserted-by":"crossref","DOI":"10.1177\/1178630220921410","article-title":"Chromium, cadmium, lead, and arsenic concentrations in water, vegetables, and seafood consumed in a coastal area in Northern Vietnam","volume":"14","author":"Ngoc","year":"2020","journal-title":"Environ. Health Insights"},{"key":"10.1016\/j.etap.2025.104640_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2019.114760","article-title":"Chemotherapeutic doses of arsenic trioxide delays hepatic regeneration by oxidative stress and hepatocyte apoptosis in partial hepatectomy rat","volume":"382","author":"Nithyananthan","year":"2019","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.etap.2025.104640_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.yrtph.2019.104539","article-title":"Arsenic exposure: A public health problem leading to several cancers","volume":"110","author":"Palma-Lara","year":"2020","journal-title":"Regul. Toxicol. Pharmacol."},{"issue":"5","key":"10.1016\/j.etap.2025.104640_bib41","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/s41419-019-1578-1","article-title":"AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair","volume":"10","author":"Pei","year":"2019","journal-title":"Cell death Dis."},{"key":"10.1016\/j.etap.2025.104640_bib42","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.mrfmmm.2012.10.003","article-title":"Zebrafish as a model system to study DNA damage and repair","volume":"743","author":"Pei","year":"2013","journal-title":"Mutat. Res. \/Fundam. Mol. Mech. Mutagen."},{"issue":"9","key":"10.1016\/j.etap.2025.104640_bib43","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT\u2013PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.etap.2025.104640_bib44","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.envpol.2018.02.020","article-title":"Risk analysis of heavy metal concentration in surface waters across the rural-urban interface of the Wen-Rui Tang River, China","volume":"237","author":"Qu","year":"2018","journal-title":"Environ. Pollut."},{"issue":"19","key":"10.1016\/j.etap.2025.104640_bib45","doi-asserted-by":"crossref","first-page":"8587","DOI":"10.1073\/pnas.1003689107","article-title":"Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2","volume":"107","author":"Rajagopalan","year":"2010","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"10","key":"10.1016\/j.etap.2025.104640_bib46","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1002\/tox.20685","article-title":"Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin","volume":"27","author":"Rocco","year":"2012","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.etap.2025.104640_bib47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ecoenv.2014.05.012","article-title":"Low dose of arsenic trioxide triggers oxidative stress in zebrafish brain: expression of antioxidant genes","volume":"107","author":"Sarkar","year":"2014","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2025.104640_bib48","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jtemb.2019.06.007","article-title":"Cytotoxic and genotoxic effects of arsenic on erythrocytes of Oryzias latipes: bioremediation using Spirulina platensis","volume":"55","author":"Sayed","year":"2019","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.etap.2025.104640_bib49","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.jclepro.2014.01.050","article-title":"Mixtures including wastes from the mussel shell processing industry: retention of arsenic, chromium and mercury","volume":"84","author":"Seco-Reigosa","year":"2014","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.etap.2025.104640_bib50","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/6185231","article-title":"Monitoring bioaccumulation (in gills and muscle tissues), hematology, and genotoxic alteration in Ctenopharyngodon idella exposed to selected heavy metals","volume":"2020","author":"Shah","year":"2020","journal-title":"BioMed. Res. Int."},{"key":"10.1016\/j.etap.2025.104640_bib51","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.chemosphere.2018.09.104","article-title":"Environmentally relevant concentration of chromium activates Nrf2 and alters transcription of related XME genes in liver of zebrafish","volume":"214","author":"Shaw","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2025.104640_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135622","article-title":"Environmentally relevant concentration of chromium induces nuclear deformities in erythrocytes and alters the expression of stress-responsive and apoptotic genes in brain of adult zebrafish","volume":"703","author":"Shaw","year":"2020","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.etap.2025.104640_bib53","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.freeradbiomed.2004.03.012","article-title":"Oxidative stress and apoptosis in metal ion-induced carcinogenesis","volume":"37","author":"Shi","year":"2004","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.etap.2025.104640_bib54","doi-asserted-by":"crossref","first-page":"11528","DOI":"10.1007\/s11356-017-8827-6","article-title":"Environmental exposure to arsenic and chromium in an industrial area","volume":"24","author":"Vimercati","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.etap.2025.104640_bib55","series-title":"Guidelines for Drinking-Water Quality: Fourth Edition Incorporating the First Addendum","author":"World Health Organization","year":"2017"},{"key":"10.1016\/j.etap.2025.104640_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxlet.2019.11.017","article-title":"Hedgehog signaling pathway regulates hexavalent chromium-induced liver fibrosis by activation of hepatic stellate cells","volume":"320","author":"Yan","year":"2020","journal-title":"Toxicol. Lett."},{"issue":"19","key":"10.1016\/j.etap.2025.104640_bib57","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1016\/j.yexcr.2013.07.012","article-title":"8-Oxoguanine DNA glycosylase 1 (ogg1) maintains the function of cardiac progenitor cells during heart formation in zebrafish","volume":"319","author":"Yan","year":"2013","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.etap.2025.104640_bib58","article-title":"Total concentrations and sources of heavy metal pollution in global river and lake water bodies from 1972 to 2017","volume":"22","author":"Zhou","year":"2020","journal-title":"Glob. Ecol. Conserv."},{"issue":"9","key":"10.1016\/j.etap.2025.104640_bib59","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1093\/carcin\/bgaa076","article-title":"Metals and molecular carcinogenesis","volume":"41","author":"Zhu","year":"2020","journal-title":"Carcinogenesis"}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925000158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925000158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T16:29:01Z","timestamp":1740846541000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668925000158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":59,"alternative-id":["S1382668925000158"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2025.104640","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mixture effects of arsenic and chromium on erythrocytic nuclear abnormalities and expression of DNA repair, tumor suppressor and apoptotic genes in liver of zebrafish","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2025.104640","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104640"}}