{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:32:07Z","timestamp":1760711527766,"version":"3.41.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.etap.2025.104712","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T06:50:21Z","timestamp":1746514221000},"page":"104712","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Long-term joint exposure of outdoor air pollutants and impaired kidney function in Korean adults: A mixture analysis based on a nationwide sample (2007\u20132019)"],"prefix":"10.1016","volume":"116","author":[{"given":"Seong-Uk","family":"Baek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Ha","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2025.104712_bib1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s11869-010-0101-8","article-title":"Particulate air pollution, systemic oxidative stress, inflammation, and atherosclerosis","volume":"4","author":"Araujo","year":"2010","journal-title":"Air Qual. Atmos. Health"},{"key":"10.1016\/j.etap.2025.104712_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.114604","article-title":"Meta analysis of health effects of ambient air pollution exposure in low- and middle-income countries","volume":"216","author":"Badida","year":"2023","journal-title":"Environ. Res"},{"key":"10.1016\/j.etap.2025.104712_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.atmosenv.2024.120856","article-title":"Association between exposure to ambient particulate matter and high sensitivity C-reactive protein: a nationwide study in South Korea, 2015\u20132018","volume":"339","author":"Baek","year":"2024","journal-title":"Atmos. Environ."},{"key":"10.1016\/j.etap.2025.104712_bib4","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","article-title":"World Health Organization 2020 guidelines on physical activity and sedentary behaviour","volume":"54","author":"Bull","year":"2020","journal-title":"Br. J. Sports Med"},{"key":"10.1016\/j.etap.2025.104712_bib5","doi-asserted-by":"crossref","first-page":"486","DOI":"10.5668\/JEHS.2021.47.5.486","article-title":"Health and economic burden attributable to particulate matter in South Korea: considering spatial variation in relative risk","volume":"47","author":"Byun","year":"2021","journal-title":"J. Environ. Health Sci."},{"key":"10.1016\/j.etap.2025.104712_bib6","doi-asserted-by":"crossref","first-page":"52610","DOI":"10.1007\/s11356-021-16031-6","article-title":"Emerging role of air pollution in chronic kidney disease","volume":"28","author":"Chen","year":"2021","journal-title":"Environ. Sci. Pollut. Res Int"},{"key":"10.1016\/j.etap.2025.104712_bib7","doi-asserted-by":"crossref","DOI":"10.4178\/epih.e2021082","article-title":"Effects of exposure to ambient air pollution on pulmonary function impairment in Korea: the 2007-2017 Korea National Health and Nutritional Examination Survey","volume":"43","author":"Choi","year":"2021","journal-title":"Epidemiol. Health"},{"key":"10.1016\/j.etap.2025.104712_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111856","article-title":"A comparative study of the disease burden attributable to PM(2.5) in China, Japan and South Korea from 1990 to 2017","volume":"209","author":"Du","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2025.104712_bib9","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1515\/reveh-2022-0252","article-title":"Health effects of air pollutant mixtures (volatile organic compounds, particulate matter, sulfur and nitrogen oxides) - a review of the literature","volume":"39","author":"Fazakas","year":"2024","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.etap.2025.104712_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/S2542-5196(22)00090-0","article-title":"Pollution and health: a progress update","volume":"6","author":"Fuller","year":"2022","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.etap.2025.104712_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101545","article-title":"Oxidative stress pathways of air pollution mediated toxicity: recent insights","volume":"34","author":"Gangwar","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.etap.2025.104712_bib12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.freeradbiomed.2019.03.008","article-title":"Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo","volume":"135","author":"Hsu","year":"2019","journal-title":"Free Radic. Biol. Med"},{"key":"10.1016\/j.etap.2025.104712_bib13","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12302-019-0284-z","article-title":"The activation of antioxidant and apoptosis pathways involved in damage of human proximal tubule epithelial cells by PM2.5 exposure","volume":"32","author":"Huang","year":"2020","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.etap.2025.104712_bib14","article-title":"Individual and joint associations of long-term exposure to air pollutants and cardiopulmonary mortality: a 22-year cohort study in Northern China","volume":"36","author":"Huang","year":"2023","journal-title":"Lancet Reg. Health West Pac."},{"key":"10.1016\/j.etap.2025.104712_bib15","article-title":"Association of air pollutants with incident chronic kidney disease in a nationally representative cohort of Korean adults","volume":"18","author":"Hwang","year":"2021","journal-title":"Int J. Environ. Res Public Health"},{"key":"10.1016\/j.etap.2025.104712_bib16","doi-asserted-by":"crossref","DOI":"10.4178\/epih.e2021015","article-title":"Establishment of the Korea National Health and Nutrition Examination Survey air pollution study dataset for the researchers on the health impact of ambient air pollution","volume":"43","author":"Hwang","year":"2021","journal-title":"Epidemiol. Health"},{"key":"10.1016\/j.etap.2025.104712_bib17","doi-asserted-by":"crossref","first-page":"244","DOI":"10.3343\/alm.2023.43.3.244","article-title":"Accuracy of the new creatinine-based equations for estimating glomerular filtration rate in Koreans","volume":"43","author":"Jeong","year":"2023","journal-title":"Ann. Lab Med"},{"key":"10.1016\/j.etap.2025.104712_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141521","article-title":"Changes in air pollution levels after COVID-19 outbreak in Korea","volume":"750","author":"Ju","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.etap.2025.104712_bib19","doi-asserted-by":"crossref","first-page":"S117","DOI":"10.1016\/j.kint.2023.10.018","article-title":"KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease","volume":"105","author":"Kdigo","year":"2024","journal-title":"Kidney Int"},{"key":"10.1016\/j.etap.2025.104712_bib20","doi-asserted-by":"crossref","first-page":"47004","DOI":"10.1289\/EHP5838","article-title":"A quantile-based g-computation approach to addressing the effects of exposure mixtures","volume":"128","author":"Keil","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2025.104712_bib21","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40557-018-0226-z","article-title":"Association between exposure to ambient air pollution and renal function in Korean adults","volume":"30","author":"Kim","year":"2018","journal-title":"Ann. Occup. Environ. Med"},{"key":"10.1016\/j.etap.2025.104712_bib22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1265\/ehpm.23-00199","article-title":"Association between short-term exposure to ambient air pollutants and biomarkers indicative of inflammation and oxidative stress: a cross-sectional study using KoGES-HEXA data","volume":"29","author":"Kim","year":"2024","journal-title":"Environ. Health Prev. Med"},{"key":"10.1016\/j.etap.2025.104712_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.116426","article-title":"Medium term moderate to low-level air pollution exposure is associated with higher C-reactive protein among healthy Danish blood donors","volume":"233","author":"Kjerulff","year":"2023","journal-title":"Environ. Res"},{"key":"10.1016\/j.etap.2025.104712_bib24","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/ije\/dyt228","article-title":"Data resource profile: the Korea National Health and nutrition examination survey (KNHANES)","volume":"43","author":"Kweon","year":"2014","journal-title":"Int J. Epidemiol."},{"key":"10.1016\/j.etap.2025.104712_bib25","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.kint.2024.04.021","article-title":"Environmental pollution to kidney disease: an updated review of current knowledge and future directions","volume":"106","author":"Lao","year":"2024","journal-title":"Kidney Int"},{"key":"10.1016\/j.etap.2025.104712_bib26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12989-022-00507-5","article-title":"A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence","volume":"19","author":"Li","year":"2022","journal-title":"Part Fibre Toxicol."},{"key":"10.1016\/j.etap.2025.104712_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2020.103355","article-title":"Relationship of chronic kidney disease with major air pollutants - a systematic review and meta-analysis of observational studies","volume":"76","author":"Liu","year":"2020","journal-title":"Environ. Toxicol. Pharm."},{"key":"10.1016\/j.etap.2025.104712_bib28","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.ijheh.2019.05.005","article-title":"Ambient particulate air pollution and circulating C-reactive protein level: a systematic review and meta-analysis","volume":"222","author":"Liu","year":"2019","journal-title":"Int J. Hyg. Environ. Health"},{"key":"10.1016\/j.etap.2025.104712_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v009.i08","article-title":"Analysis of complex survey samples","volume":"9","author":"Lumley","year":"2004","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.etap.2025.104712_bib30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1515\/reveh-2022-0090","article-title":"Cardiovascular disease, mortality and exposure to particulate matter (PM): a systematic review and meta-analysis","volume":"39","author":"Mohammadi","year":"2024","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.etap.2025.104712_bib31","doi-asserted-by":"crossref","DOI":"10.35371\/aoem.2023.35.e51","article-title":"Association between ambient particulate matter levels and hypertension: results from the Korean Genome and Epidemiology Study","volume":"35","author":"Na","year":"2023","journal-title":"Ann. Occup. Environ. Med"},{"key":"10.1016\/j.etap.2025.104712_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2023.114318","article-title":"Blood Pb levels are associated with prostate cancer prevalence among general adult males: linking National Cancer Registry (2002-2017) and KNHANES (2008-2017) databases of Korea","volume":"256","author":"Nam","year":"2024","journal-title":"Int J. Hyg. Environ. Health"},{"key":"10.1016\/j.etap.2025.104712_bib33","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4081\/hi.2006.115","article-title":"Endothelial damage due to air pollution","volume":"2","author":"Nodari","year":"2006","journal-title":"Heart Int"},{"key":"10.1016\/j.etap.2025.104712_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113080","article-title":"Association between exposure to fine particulate matter and kidney function: results from the Korea National Health and Nutrition Examination Survey","volume":"212","author":"Oh","year":"2022","journal-title":"Environ. Res"},{"key":"10.1016\/j.etap.2025.104712_bib35","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1289\/ehp.0901181","article-title":"Long-term exposure to constituents of fine particulate air pollution and mortality: results from the California Teachers Study","volume":"118","author":"Ostro","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2025.104712_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2023.114312","article-title":"Association of blood metal exposure with age at menarche in Korean women: KNHANES (2008-2017)","volume":"256","author":"Park","year":"2024","journal-title":"Int J. Hyg. Environ. Health"},{"key":"10.1016\/j.etap.2025.104712_bib37","doi-asserted-by":"crossref","first-page":"559","DOI":"10.23876\/j.krcp.24.103","article-title":"Air pollution can affect kidney disease? Scientific evidence from epidemiology to experimental studies","volume":"43","author":"Park","year":"2024","journal-title":"Kidney Res Clin. Pr."},{"key":"10.1016\/j.etap.2025.104712_bib38","doi-asserted-by":"crossref","first-page":"183","DOI":"10.7326\/M20-4366","article-title":"Development and validation of a modified full age spectrum creatinine-based equation to estimate glomerular filtration rate: a cross-sectional analysis of pooled data","volume":"174","author":"Pottel","year":"2021","journal-title":"Ann. Intern Med"},{"key":"10.1016\/j.etap.2025.104712_bib39","doi-asserted-by":"crossref","DOI":"10.35371\/aoem.2023.35.e31","article-title":"Particulate matter concentration effects on attention to environmental issues: a cross-sectional study among residents in Korea's Pohang Industrial Complex","volume":"35","author":"Ryu","year":"2023","journal-title":"Ann. Occup. Environ. Med"},{"key":"10.1016\/j.etap.2025.104712_bib40","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s00420-021-01808-6","article-title":"Role of air pollution in chronic kidney disease: an update on evidence, mechanisms and mitigation strategies","volume":"95","author":"Shubham","year":"2022","journal-title":"Int Arch. Occup. Environ. Health"},{"key":"10.1016\/j.etap.2025.104712_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.160064","article-title":"Trends in urban air pollution over the last two decades: a global perspective","volume":"858","author":"Sicard","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.etap.2025.104712_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph19127511","article-title":"Recent insights into particulate matter (PM(2.5))-mediated toxicity in humans: an overview","volume":"19","author":"Thangavel","year":"2022","journal-title":"Int J. Environ. Res Public Health"},{"key":"10.1016\/j.etap.2025.104712_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121647","article-title":"Association of long-term exposure to air pollutant mixture and incident cardiovascular disease in a highly polluted region of China","volume":"328","author":"Wen","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.etap.2025.104712_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115039","article-title":"Combined effects of ambient air pollution and PM(2.5) components on renal function and the potential mediation effects of metabolic risk factors in China","volume":"259","author":"Wen","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"year":"2021","series-title":"Air Quality Guidelines - Update 2021","author":"WHO","key":"10.1016\/j.etap.2025.104712_bib45"},{"key":"10.1016\/j.etap.2025.104712_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135522","article-title":"Association between air pollutants and development of chronic kidney disease: a systematic review and meta-analysis","volume":"706","author":"Wu","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.etap.2025.104712_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23610","article-title":"Association of air pollution and risk of chronic kidney disease: a systematic review and meta-analysis","volume":"38","author":"Xu","year":"2024","journal-title":"J. Biochem Mol. Toxicol."},{"key":"10.1016\/j.etap.2025.104712_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.110867","article-title":"Ambient air pollution exposure and risk of chronic kidney disease: a systematic review of the literature and meta-analysis","volume":"195","author":"Ye","year":"2021","journal-title":"Environ. Res"},{"key":"10.1016\/j.etap.2025.104712_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.115458","article-title":"Long-term trends and affecting factors in the concentrations of criteria air pollutants in South Korea","volume":"317","author":"Yeo","year":"2022","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.etap.2025.104712_bib50","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.scitotenv.2017.01.221","article-title":"The effects of particulate matter on inflammation of respiratory system: differences between male and female","volume":"586","author":"Yoshizaki","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.etap.2025.104712_bib51","first-page":"30","article-title":"Multiple imputation with multivariate imputation by chained equation (MICE) package","volume":"4","author":"Zhang","year":"2016","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.etap.2025.104712_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2023.117885","article-title":"Association of the components of ambient fine particulate matter (PM(2.5)) and chronic kidney disease prevalence in China","volume":"339","author":"Zhang","year":"2023","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.etap.2025.104712_bib53","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1186\/s12916-024-03596-5","article-title":"Air pollution and risk of 32 health conditions: outcome-wide analyses in a population-based prospective cohort in Southwest China","volume":"22","author":"Zhou","year":"2024","journal-title":"BMC Med."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925000870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925000870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T23:14:32Z","timestamp":1748733272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668925000870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":53,"alternative-id":["S1382668925000870"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2025.104712","relation":{},"ISSN":["1382-6689"],"issn-type":[{"type":"print","value":"1382-6689"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term joint exposure of outdoor air pollutants and impaired kidney function in Korean adults: A mixture analysis based on a nationwide sample (2007\u20132019)","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2025.104712","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104712"}}