{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:09:37Z","timestamp":1790352577900,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100016173","name":"Rajshahi University","doi-asserted-by":"publisher","award":["1299\/5\/52\/RU\/Science\/2021\\u20132022"],"award-info":[{"award-number":["1299\/5\/52\/RU\/Science\/2021\\u20132022"]}],"id":[{"id":"10.13039\/501100016173","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016173","name":"Rajshahi University","doi-asserted-by":"publisher","award":["A-795\/6\\u2013109"],"award-info":[{"award-number":["A-795\/6\\u2013109"]}],"id":[{"id":"10.13039\/501100016173","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K06137"],"award-info":[{"award-number":["23K06137"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["16H05834"],"award-info":[{"award-number":["16H05834"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K28239"],"award-info":[{"award-number":["23K28239"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.etap.2025.104824","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T08:25:19Z","timestamp":1758702319000},"page":"104824","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Relationship of fractalkine with arsenic exposure and the risk of cardiovascular diseases"],"prefix":"10.1016","volume":"119","author":[{"given":"Nesar","family":"Uddin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajoana Karim","family":"Rimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Goni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayan Chandra","family":"Mohanto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamrun Nahar","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faysal","family":"Abedin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharmin Akter","family":"Beauty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biplob","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sobuj","family":"Mia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon Jahan","family":"Sarder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajib","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mainul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Shadat M.","family":"Noman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Ashraful","family":"Hoque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daigo","family":"Sumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koren K.","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahangir Alam","family":"Saud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiichiro","family":"Himeno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0878-915X","authenticated-orcid":false,"given":"Khaled","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"ement_1","key":"10.1016\/j.etap.2025.104824_bib1","article-title":"5234 KAND567, the first selective small molecule CX3CR1 antagonist in clinical development, mediates anti-inflammatory cardioprotective effects in rodent models of atherosclerosis and myocardial infarction","volume":"40","author":"Abdelmoaty","year":"2019","journal-title":"Eur. Heart J."},{"issue":"15","key":"10.1016\/j.etap.2025.104824_bib2","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1161\/CIRCULATIONAHA.113.005015","article-title":"Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis","volume":"129","author":"Allahverdian","year":"2014","journal-title":"Circulation"},{"issue":"23 1","key":"10.1016\/j.etap.2025.104824_bib3","article-title":"HDL cholesterol and protective factors in atherosclerosis","volume":"109","author":"Assmann","year":"2004","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib4","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s12011-022-03153-2","article-title":"Mechanisms of arsenic Exposure-Induced hypertension and atherosclerosis: an updated overview","volume":"201","author":"Balarastaghi","year":"2023","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.etap.2025.104824_bib5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s11883-012-0235-2","article-title":"High-density lipoprotein and atherosclerosis: the role of antioxidant activity","volume":"14","author":"Bandeali","year":"2012","journal-title":"Curr. Atheroscler. Rep."},{"issue":"3","key":"10.1016\/j.etap.2025.104824_bib6","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1161\/CIRCOUTCOMES.115.002436","article-title":"Is isolated low HDL-C a CVD risk factor?: new insights from the framingham offspring study","volume":"9","author":"Bartlett","year":"2016","journal-title":"Circ. Cardiovasc. Qual. Outcomes"},{"issue":"12","key":"10.1016\/j.etap.2025.104824_bib7","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/s41569-019-0227-9","article-title":"Vascular smooth muscle cells in atherosclerosis","volume":"16","author":"Basatemur","year":"2019","journal-title":"Nat. Rev. Cardiol."},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.socscimed.2003.10.028","article-title":"Understanding the role of mediating risk factors and proxy effects in the association between socio-economic status and untreated hypertension","volume":"59","author":"Bell","year":"2004","journal-title":"Soc. Sci. Med"},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib9","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. Ser. B Method."},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0021-9150(03)00097-2","article-title":"Adhesion molecules and atherosclerosis","volume":"170","author":"Blankenberg","year":"2003","journal-title":"Atherosclerosis"},{"issue":"8","key":"10.1016\/j.etap.2025.104824_bib11","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.3390\/cells10081869","article-title":"HDL in atherosclerotic cardiovascular disease: in search of a role","volume":"10","author":"Casula","year":"2021","journal-title":"Cells"},{"issue":"19","key":"10.1016\/j.etap.2025.104824_bib12","doi-asserted-by":"crossref","first-page":"5770","DOI":"10.1016\/j.watres.2010.05.040","article-title":"The association between arsenic exposure from drinking water and cerebrovascular disease mortality in Taiwan","volume":"44","author":"Cheng","year":"2010","journal-title":"Water Res"},{"issue":"9","key":"10.1016\/j.etap.2025.104824_bib13","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1161\/01.STR.28.9.1717","article-title":"Dose-response relationship between prevalence of cerebrovascular disease and ingested inorganic arsenic","volume":"28","author":"Chiou","year":"1997","journal-title":"Stroke"},{"issue":"7","key":"10.1016\/j.etap.2025.104824_bib14","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1161\/01.CIR.0000057548.68243.42","article-title":"Decreased atherosclerotic lesion formation in CX3CR1\/apolipoprotein e double knockout mice","volume":"107","author":"Combadi\u00e8re","year":"2003","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib15","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.atherosclerosis.2009.02.041","article-title":"HDL cholesterol protects against cardiovascular disease in both genders, at all ages and at all levels of risk","volume":"206","author":"Cooney","year":"2009","journal-title":"Atherosclerosis"},{"issue":"12","key":"10.1016\/j.etap.2025.104824_bib16","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1161\/01.ATV.0000190672.36490.7b","article-title":"Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy","volume":"25","author":"Dam\u00e5s","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"23 1","key":"10.1016\/j.etap.2025.104824_bib17","article-title":"Role of endothelial dysfunction in atherosclerosis","volume":"109","author":"Davignon","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.etap.2025.104824_bib18","unstructured":"Department of Public Health Engineering, 2001Bangladesh and British Geological Survey. 2001. Arsenic Contamination of Groundwater in Bangladesh. Available at:\u3008https:\/\/www2.bgs.ac.uk\/groundwater\/health\/arsenic\/Bangladesh\/home.html\u3009(Accessed on 22 2024."},{"issue":"6","key":"10.1016\/j.etap.2025.104824_bib19","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/eci.12443","article-title":"Modulation of platelet and monocyte function by the chemokine fractalkine (CX3 CL1) in cardiovascular disease","volume":"45","author":"Flierl","year":"2015","journal-title":"Eur. J. Clin. Invest"},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib20","first-page":"370","article-title":"Multiple actions of high-density lipoprotein","volume":"23","author":"Florentin","year":"2008","journal-title":"Eur. J. Clin. Invest"},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib21","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1161\/HYPERTENSIONAHA.119.14240","article-title":"High blood pressure and cardiovascular disease","volume":"75","author":"Fuchs","year":"2020","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib22","doi-asserted-by":"crossref","first-page":"4330","DOI":"10.1038\/s41598-017-04552-5","article-title":"The life-course impact of smoking on hypertension, myocardial infarction and respiratory diseases","volume":"7","author":"Gao","year":"2017","journal-title":"Sci. Rep."},{"issue":"41","key":"10.1016\/j.etap.2025.104824_bib23","doi-asserted-by":"crossref","first-page":"37993","DOI":"10.1074\/jbc.M106434200","article-title":"Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)","volume":"276","author":"Garton","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib24","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1161\/CIRCRESAHA.115.306301","article-title":"Endothelial cell dysfunction and the pathobiology of atherosclerosis","volume":"118","author":"Gimbrone","year":"2016","journal-title":"Cir. Res."},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib25","first-page":"503","article-title":"Atherosclerosis","volume":"104","author":"Glass","year":"2001","journal-title":"Road. Ahead Cell"},{"issue":"8","key":"10.1016\/j.etap.2025.104824_bib26","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.4049\/jimmunol.164.8.4313","article-title":"CX3C-chemokine, fractalkine-enhanced adhesion of THP-1 cells to endothelial cells through integrin-dependent and -independent mechanisms","volume":"164","author":"Goda","year":"2000","journal-title":"J. Immunol. (Baltim. Md. 1950)"},{"issue":"7","key":"10.1016\/j.etap.2025.104824_bib27","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1113\/EP085104","article-title":"Fractalkine neutralization improves cardiac function after myocardial infarction","volume":"100","author":"Gu","year":"2015","journal-title":"Exp. Physiol."},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib28","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1161\/HYPERTENSIONAHA.117.07802","article-title":"Oxidative stress, inflammation, and vascular aging in hypertension","volume":"70","author":"Guzik","year":"2017","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0175154","article-title":"Association between arsenic exposure and soluble thrombomodulin: a cross sectional study in Bangladesh","volume":"12","author":"Hasibuzzaman","year":"2017","journal-title":"PloS One"},{"issue":"9","key":"10.1016\/j.etap.2025.104824_bib30","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1038\/nm.2930","article-title":"The not-so-simple HDL story: a new era for quantifying HDL and cardiovascular risk?","volume":"18","author":"Heinecke","year":"2012","journal-title":"Nat. Med"},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib31","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1160\/TH13-08-0640","article-title":"Fractalkine promotes platelet activation and vascular dysfunction in congestive heart failure","volume":"111","author":"Hildemann","year":"2014","journal-title":"Thromb. Haemost."},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib32","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12940-017-0231-7","article-title":"Chronic exposure to arsenic, LINE-1 hypomethylation, and blood pressure: a cross-sectional study in Bangladesh","volume":"16","author":"Hossain","year":"2017","journal-title":"Environ. Health"},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib33","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.taap.2014.09.011","article-title":"Elevated levels of plasma uric acid and its relation to hypertension in arsenic-endemic human individuals in Bangladesh","volume":"281","author":"Huda","year":"2014","journal-title":"Toxicol. Appl. Pharm."},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib34","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1182\/blood-2002-12-3775","article-title":"The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion","volume":"102","author":"Hundhausen","year":"2003","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib35","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0092-8674(00)80438-9","article-title":"Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion","volume":"91","author":"Imai","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.etap.2025.104824_bib36","first-page":"64","article-title":"Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh","volume":"10","author":"Islam","year":"2011","journal-title":"Environ. Health a Global Access Science Source"},{"issue":"12","key":"10.1016\/j.etap.2025.104824_bib37","doi-asserted-by":"crossref","first-page":"4522","DOI":"10.3390\/ijerph9124522","article-title":"Association between hypertension and chronic arsenic exposure in drinking water: a cross-sectional study in Bangladesh","volume":"9","author":"Islam","year":"2012","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"5","key":"10.1016\/j.etap.2025.104824_bib38","doi-asserted-by":"crossref","first-page":"362","DOI":"10.3390\/antiox9050362","article-title":"High-density lipoprotein (HDL) triglyceride and oxidized HDL: new lipid biomarkers of lipoprotein-related atherosclerotic cardiovascular disease","volume":"9","author":"Ito","year":"2020","journal-title":"Antioxidants"},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib39","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1289\/ehp.1307839","article-title":"Association between lifetime exposure to inorganic arsenic in drinking water and coronary heart disease in Colorado residents","volume":"123","author":"James","year":"2015","journal-title":"Environ. Health Perspect."},{"issue":"5","key":"10.1016\/j.etap.2025.104824_bib40","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1124\/mi.10.5.3","article-title":"Fractalkine\/CX3CL1: a potential new target for inflammatory diseases","volume":"10","author":"Jones","year":"2010","journal-title":"Mol. Inter."},{"issue":"11","key":"10.1016\/j.etap.2025.104824_bib41","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1097\/HJH.0000000000003238","article-title":"Occupational risk factors for hypertension","volume":"40","author":"Kang","year":"2022","journal-title":"J. Hypertens."},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib42","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/toxsci\/kft130","article-title":"Increases in oxidized low-density lipoprotein and other inflammatory and adhesion molecules with a concomitant decrease in high-density lipoprotein in the individuals exposed to arsenic in Bangladesh","volume":"135","author":"Karim","year":"2013","journal-title":"Toxicol. Sci Off. J. Soc. Toxicol."},{"key":"10.1016\/j.etap.2025.104824_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.110864","article-title":"Arsenic, blood pressure, and hypertension in the strong heart family study","volume":"195","author":"Kaufman","year":"2021","journal-title":"Environ. Res."},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib44","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0279893","article-title":"Association between serum periostin levels and the severity of arsenic-induced skin lesions","volume":"18","author":"Khatun","year":"2023","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib45","doi-asserted-by":"crossref","first-page":"47003","DOI":"10.1289\/EHP13018","article-title":"Arsenic exposure-related hypertension in Bangladesh and reduced circulating nitric oxide bioavailability","volume":"132","author":"Khatun","year":"2024","journal-title":"Environ. Health Perspect."},{"issue":"22","key":"10.1016\/j.etap.2025.104824_bib46","first-page":"e156","article-title":"In vivo structure\/function and expression analysis of the CX3C chemokine fractalkine","volume":"118","author":"Kim","year":"2011","journal-title":"Blood J. Am. Soc. Hematol."},{"key":"10.1016\/j.etap.2025.104824_bib47","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.phrs.2017.11.003","article-title":"Hypertension and cardiovascular risk: general aspects","volume":"129","author":"Kjeldsen","year":"2018","journal-title":"Pharmacol. Res."},{"issue":"3","key":"10.1016\/j.etap.2025.104824_bib48","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1172\/JCI15555","article-title":"Decreased atherosclerosis in CX3CR1-\/- mice reveals a role for fractalkine in atherogenesis","volume":"111","author":"Lesnik","year":"2003","journal-title":"J. Clin. Invest"},{"issue":"3","key":"10.1016\/j.etap.2025.104824_bib49","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.cardiores.2005.09.009","article-title":"Oxidized LDL, a critical factor in atherogenesis","volume":"68","author":"Li","year":"2005","journal-title":"Cardiovasc. Res."},{"issue":"13-14","key":"10.1016\/j.etap.2025.104824_bib50","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.cca.2011.03.036","article-title":"Fractalkine\/CX3CR1 and atherosclerosis","volume":"412","author":"Liu","year":"2011","journal-title":"Clin. Chim. Acta"},{"issue":"14","key":"10.1016\/j.etap.2025.104824_bib51","doi-asserted-by":"crossref","first-page":"4821","DOI":"10.3390\/jcm12144821","article-title":"Fractalkine signalling (CX3CL1\/CX3CR1 axis) as an emerging target in coronary artery disease","volume":"12","author":"Loh","year":"2023","journal-title":"J. Clin. Med."},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib52","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/(SICI)1098-2280(1998)32:4<301::AID-EM3>3.0.CO;2-I","article-title":"Association between the clastogenic effect in peripheral lymphocytes and human exposure to arsenic through drinking water","volume":"32","author":"M\u00e4ki-Paakkanen","year":"1998","journal-title":"Environ. Mol. Mutagen"},{"issue":"10","key":"10.1016\/j.etap.2025.104824_bib53","doi-asserted-by":"crossref","DOI":"10.1289\/EHP14410","article-title":"Long-term exposure to arsenic in community water supplies and risk of cardiovascular disease among women in the california teachers study","volume":"132","author":"Medgyesi","year":"2024","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2025.104824_bib54","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s10557-011-6341-5","article-title":"Oxidized LDL, LOX-1 and atherosclerosis","volume":"25","author":"Mitra","year":"2011","journal-title":"Cardiovasc. Drugs Ther."},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib55","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1021\/acs.est.2c04816","article-title":"Quantitative measurement of phthalate exposure biomarker levels in diaper-extracted urine of Japanese toddlers and cumulative risk assessment: an adjunct study of JECS birth cohort","volume":"57","author":"Mohanto","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.etap.2025.104824_bib56","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.envres.2017.01.028","article-title":"Low-level arsenic in drinking water and risk of incident myocardial infarction: a cohort study","volume":"154","author":"Monrad","year":"2017","journal-title":"Environ. Res."},{"issue":"6","key":"10.1016\/j.etap.2025.104824_bib57","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s11883-012-0280-x","article-title":"Arsenic exposure and cardiovascular disease: an updated systematic review","volume":"14","author":"Moon","year":"2012","journal-title":"Curr. Atheroscler. Rep."},{"issue":"6","key":"10.1016\/j.etap.2025.104824_bib58","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1093\/ije\/dyx202","article-title":"A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease","volume":"46","author":"Moon","year":"2017","journal-title":"Int. J. Epidemiol."},{"issue":"6","key":"10.1016\/j.etap.2025.104824_bib59","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1097\/FJC.0000000000001130","article-title":"Antagonizing the CX3CR1 receptor markedly reduces development of cardiac hypertrophy after transverse aortic constriction in mice","volume":"78","author":"Nemska","year":"2021","journal-title":"J. Cardiovasc. Pharm."},{"key":"10.1016\/j.etap.2025.104824_bib60","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.959285","article-title":"Hypertension as a risk factor for atherosclerosis: cardiovascular risk assessment","volume":"9","author":"Poznyak","year":"2022","journal-title":"Front Cardiovasc. Med."},{"issue":"9943","key":"10.1016\/j.etap.2025.104824_bib61","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0140-6736(14)61217-4","article-title":"HDL and cardiovascular disease","volume":"384","author":"Rader","year":"2014","journal-title":"Lancet (Lond. Engl. )"},{"issue":"9","key":"10.1016\/j.etap.2025.104824_bib62","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1038\/nm.2937","article-title":"Is it time to revise the HDL cholesterol hypothesis?","volume":"18","author":"Rader","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.etap.2025.104824_bib63","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.chemosphere.2014.08.003","article-title":"Associations of total arsenic in drinking water, hair and nails with serum vascular endothelial growth factor in arsenic-endemic individuals in Bangladesh","volume":"120","author":"Rahman","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2025.104824_bib64","series-title":"Arsenic Pollution: A Global Synthesis","author":"Ravenscroft","year":"2011"},{"issue":"25","key":"10.1016\/j.etap.2025.104824_bib65","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1056\/NEJMoa1409065","article-title":"HDL cholesterol efflux capacity and incident cardiovascular events","volume":"371","author":"Rohatgi","year":"2014","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.etap.2025.104824_bib66","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nrcardio.2015.124","article-title":"Dysfunctional HDL and atherosclerotic cardiovascular disease","volume":"13","author":"Rosenson","year":"2016","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.etap.2025.104824_bib67","first-page":"1","article-title":"Gender differences in the risk of metabolic syndrome among chronic arsenic-exposed individuals in Bangladesh","volume":"14","author":"Sarker","year":"2021","journal-title":"Expo. Health"},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib68","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1182\/blood-2002-10-3260","article-title":"Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion","volume":"103","author":"Sch\u00e4fer","year":"2004","journal-title":"Blood"},{"issue":"2-3","key":"10.1016\/j.etap.2025.104824_bib69","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/13547500500087913","article-title":"Human nails as a biomarker of arsenic exposure from well water in inner Mongolia: comparing atomic fluorescence spectrometry and neutron activation analysis","volume":"10","author":"Schmitt","year":"2005","journal-title":"Biomarkers"},{"issue":"7","key":"10.1016\/j.etap.2025.104824_bib70","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1161\/CIRCULATIONAHA.107.695189","article-title":"Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets","volume":"116","author":"Schulz","year":"2007","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.etap.2025.104824_bib71","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.2337\/db10-0956","article-title":"Fractalkine is a novel human adipochemokine associated with type 2 diabetes","volume":"60","author":"Shah","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.etap.2025.104824_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125790","article-title":"Association between chronic arsenic exposure and the characteristic features of asthma","volume":"246","author":"Siddique","year":"2020","journal-title":"Chemosphere"},{"issue":"6","key":"10.1016\/j.etap.2025.104824_bib73","first-page":"477","article-title":"Association of multiple biomarkers and classical risk factors with early carotid atherosclerosis: results from the gutenberg health study","volume":"103","author":"Sinning","year":"2014","journal-title":"Clin. Res. Cardiol Off. J. Ger. Card. Soc."},{"issue":"6","key":"10.1016\/j.etap.2025.104824_bib74","doi-asserted-by":"crossref","first-page":"506","DOI":"10.3961\/jpmph.22.264","article-title":"Effects of marital status and income on hypertension: the Korean genome and epidemiology study (KoGES)","volume":"55","author":"Son","year":"2022","journal-title":"J. Prev. Med. Public Health"},{"issue":"2","key":"10.1016\/j.etap.2025.104824_bib75","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/toxsci\/kfn236","article-title":"Arsenic and cardiovascular disease","volume":"107","author":"States","year":"2009","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"10.1016\/j.etap.2025.104824_bib76","article-title":"Primary prevention of cardiovascular disease: a review of contemporary guidance and literature","volume":"6","author":"Stewart","year":"2017","journal-title":"JRSM Cardiovasc. Dis."},{"issue":"5","key":"10.1016\/j.etap.2025.104824_bib77","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1136\/jech-2021-217006","article-title":"Association of education levels with the risk of hypertension and hypertension control: a nationwide cohort study in Chinese adults","volume":"76","author":"Sun","year":"2022","journal-title":"J. Epidemiol. Commun. Health"},{"issue":"4","key":"10.1016\/j.etap.2025.104824_bib78","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1080\/14397595.2020.1868675","article-title":"A phase 2 study of E6011, an anti-Fractalkine monoclonal antibody, in patients with rheumatoid arthritis inadequately responding to biological disease-modifying antirheumatic drugs","volume":"31","author":"Tanaka","year":"2021","journal-title":"Mod. Rheuma"},{"key":"10.1016\/j.etap.2025.104824_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.134277","article-title":"Elevated serum periostin levels among arsenic-exposed individuals and their associations with the features of asthma","volume":"298","author":"Tony","year":"2022","journal-title":"Chemosphere"},{"issue":"11","key":"10.1016\/j.etap.2025.104824_bib80","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S1471-4906(01)02051-8","article-title":"Fractalkine and vascular injury","volume":"22","author":"Umehara","year":"2001","journal-title":"Trends Immunol."},{"issue":"15","key":"10.1016\/j.etap.2025.104824_bib81","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1161\/01.CIR.0000015862.64816.B2","article-title":"Biological gradient between long-term arsenic exposure and carotid atherosclerosis","volume":"105","author":"Wang","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.etap.2025.104824_bib82","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/715148","article-title":"Circulating fractalkine levels predict the development of the metabolic syndrome","volume":"2014","author":"Xueyao","year":"2014","journal-title":"Int. J. Endocrinol."},{"key":"10.1016\/j.etap.2025.104824_bib83","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12944-020-01232-8","article-title":"Dysregulated serum lipid profile and its correlation to disease activity in young female adults diagnosed with systemic lupus erythematosus: a cross-sectional study","volume":"19","author":"Zhou","year":"2020","journal-title":"Lipids Health Dis."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925001991?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925001991?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T17:28:56Z","timestamp":1778606936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668925001991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":83,"alternative-id":["S1382668925001991"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2025.104824","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship of fractalkine with arsenic exposure and the risk of cardiovascular diseases","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2025.104824","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104824"}}