{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:32:17Z","timestamp":1773865937351,"version":"3.50.1"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Gobierno de Espa\u00f1a Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019629","name":"Universidad de Burgos","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019629","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.etap.2025.104874","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T16:55:53Z","timestamp":1763657753000},"page":"104874","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Long-term impact of oral gestational PM10 exposure on morris water maze performance and hippocampal gene expression"],"prefix":"10.1016","volume":"120","author":[{"given":"Ruiz-Sobremazas","family":"Diego","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coca","family":"Mario","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morales-Navas","family":"Miguel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nerea Rios","family":"Nieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodulfo-C\u00e1rdenas","family":"Roc\u00edo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colomina","family":"Maria Teresa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00f3pez-Granero","family":"Caridad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanchez-Santed","family":"Fernando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Perez-Fernandez","family":"Cristian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2025.104874_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jth.2021.101249","article-title":"A review of the effect of traffic-related air pollution around schools on student health and its mitigation","volume":"23","author":"An","year":"2021","journal-title":"J. Transp. Health"},{"issue":"9","key":"10.1016\/j.etap.2025.104874_bib2","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1080\/15287390306381","article-title":"Coarse(PM(2.5-10)), fine(PM(2.5)), and ultrafine air pollution particles induce\/increase immune costimulatory receptors on human blood-derived monocytes but not on alveolar macrophages","volume":"66","author":"Becker","year":"2003","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"10.1016\/j.etap.2025.104874_bib3","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3389\/fnana.2019.00100","article-title":"Developmental changes of glutamate and gaba receptor densities in wistar rats","volume":"13","author":"Behuet","year":"2019","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.etap.2025.104874_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2024.114595","article-title":"Sex differences in spontaneous behavior and cognition in mice using an automated behavior monitoring system","volume":"283","author":"Bernstein","year":"2024","journal-title":"Physiol. Behav."},{"issue":"12","key":"10.1016\/j.etap.2025.104874_bib5","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1080\/10473289.2006.10464571","article-title":"Continuous monitoring of particle emissions during showering","volume":"56","author":"Cowen","year":"2006","journal-title":"J. Air Waste Manag. Assoc. (1995)"},{"issue":"2","key":"10.1016\/j.etap.2025.104874_bib6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0006-8993(94)90243-7","article-title":"A behavioural analysis of rats with damage to the medial prefrontal cortex using the Morris water maze: evidence for behavioural flexibility, but not for impaired spatial navigation","volume":"652","author":"de Bruin","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.etap.2025.104874_bib7","article-title":"The hippocampal glutamate\/GABA System is Affected by Aging but not by an Alzheimer\u2019s Disease-Like Pathology in Rats","author":"Burnyasheva","year":"2023","journal-title":"Res. Sq."},{"issue":"12","key":"10.1016\/j.etap.2025.104874_bib8","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1134\/S0006297923120027","article-title":"Changes in the Glutamate\/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development","volume":"88","author":"Burnyasheva","year":"2023","journal-title":"Biochem. Biokhimiia"},{"issue":"3","key":"10.1016\/j.etap.2025.104874_bib9","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.3390\/ijerph19031405","article-title":"Air Pollution and Cognitive Impairment across the Life Course in Humans: A Systematic Review with Specific Focus on Income Level of Study Area","volume":"19","author":"Chandra","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"17","key":"10.1016\/j.etap.2025.104874_bib10","doi-asserted-by":"crossref","first-page":"14367","DOI":"10.1074\/jbc.C200074200","article-title":"Aging and surface expression of hippocampal NMDA receptors","volume":"277","author":"Clayton","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.etap.2025.104874_bib11","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.envres.2016.01.018","article-title":"Exposure to air pollution and cognitive functioning across the life course--a systematic literature review","volume":"147","author":"Clifford","year":"2016","journal-title":"Environ. Res."},{"key":"10.1016\/j.etap.2025.104874_bib12","doi-asserted-by":"crossref","unstructured":"Coca, M., Perez-Fernandez, C., Abreu, A.C., Salmer\u00f3n, A.M., Morales-Navas, M., Ruiz-Sobremazas, D., Colomina, T., Fern\u00e1ndez, I., & Sanchez-Santed, F. (2024). Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability. bioRxiv. https:\/\/doi.org\/10.1101\/2024.11.04.621795.","DOI":"10.1101\/2024.11.04.621795"},{"issue":"8","key":"10.1016\/j.etap.2025.104874_bib13","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1177\/0192623319878400","article-title":"The Impact of Inhaled Ambient Ultrafine Particulate Matter on Developing Brain: Potential Importance of Elemental Contaminants","volume":"47","author":"Cory-Slechta","year":"2019","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.etap.2025.104874_bib14","series-title":"Advances in Neurotoxicology","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.ant.2017.07.001","article-title":"Traffic-related air pollution and neurodegenerative diseases: epidemiological and experimental evidence, and potential underlying Mechanisms","author":"Costa","year":"2017"},{"key":"10.1016\/j.etap.2025.104874_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2020.107523","article-title":"Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders","volume":"210","author":"Costa","year":"2020","journal-title":"Pharmacol. Ther."},{"issue":"5","key":"10.1016\/j.etap.2025.104874_bib16","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0031-9384(90)90014-U","article-title":"Sex differences in the development of the motor activity circadian rhythm in rats under constant light","volume":"47","author":"D\u00edez-Noguera","year":"1990","journal-title":"Physiol. Behav."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib17","article-title":"Persistent Organic Pollutant (POP) levels in human breast milk and Municipal Waste Incineration (MWI)","volume":"2016","author":"Douglas","year":"2016","journal-title":"ISEE Conf. Abstr. 28"},{"issue":"15","key":"10.1016\/j.etap.2025.104874_bib18","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1016\/j.neuron.2023.05.002","article-title":"NMDA receptor functions in health and disease: Old actor, new dimensions","volume":"111","author":"Dupuis","year":"2023","journal-title":"Neuron"},{"key":"10.1016\/j.etap.2025.104874_bib19","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ecoenv.2019.03.090","article-title":"Prenatal exposure to diesel exhaust particles causes anxiety, spatial memory disorders with alters expression of hippocampal pro-inflammatory cytokines and NMDA receptor subunits in adult male mice offspring","volume":"176","author":"Ehsanifar","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s40201-020-00600-x","article-title":"Learning and memory disorders related to hippocampal inflammation following exposure to air pollution","volume":"19","author":"Ehsanifar","year":"2021","journal-title":"J. Environ. Health Sci. Eng."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib21","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.molbrainres.2005.03.013","article-title":"Differential expression of GABA(A) receptor subunits in the distinct nuclei of the rat amygdala. Brain research","volume":"138","author":"Fujimura","year":"2005","journal-title":"Mol. brain Res."},{"issue":"2","key":"10.1016\/j.etap.2025.104874_bib22","doi-asserted-by":"crossref","first-page":"749","DOI":"10.3390\/ijerph19020749","article-title":"The Effects of Traffic Air Pollution in and around Schools on Executive Function and Academic Performance in Children: A Rapid Review","volume":"19","author":"Gartland","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.etap.2025.104874_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/782462","article-title":"The adverse effects of air pollution on the nervous system","volume":"2012","author":"Genc","year":"2012","journal-title":"J. Toxicol."},{"key":"10.1016\/j.etap.2025.104874_bib24","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.neubiorev.2020.03.010","article-title":"Sex differences in the glutamate system: Implications for addiction","volume":"113","author":"Giacometti","year":"2020","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.etap.2025.104874_bib25","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.brainresbull.2022.11.011","article-title":"Sex-specific role of hippocampal NMDA-Erk-mTOR signaling in fear extinction of adolescent mice","volume":"192","author":"Glavonic","year":"2023","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.etap.2025.104874_bib26","article-title":"Statistical modeling with litter as a random effect in mixed models to manage intralitter likeness","volume":"77","author":"Golub","year":"2020","journal-title":"Neurotoxicology Teratol."},{"key":"10.1016\/j.etap.2025.104874_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105510","article-title":"Toxicity of urban air pollution particulate matter in developing and adult mouse brain: comparison of total and filter-eluted nanoparticles","volume":"136","author":"Haghani","year":"2020","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib28","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0006-8993(93)90287-W","article-title":"Sex differences in NMDA receptor mediated responses in rats","volume":"620","author":"H\u00f6nack","year":"1993","journal-title":"Brain Res."},{"issue":"11","key":"10.1016\/j.etap.2025.104874_bib29","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.tins.2023.08.010","article-title":"Air pollution, glymphatic impairment, and Alzheimer's disease","volume":"46","author":"Hussain","year":"2023","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.etap.2025.104874_bib30","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3389\/fnmol.2018.00266","article-title":"Sex differences in synaptic plasticity: hormones and beyond","volume":"11","author":"Hyer","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.etap.2025.104874_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127453","article-title":"Atmospheric particulate matter and potentially hazardous compounds around residential\/road side soil in an urban area","volume":"259","author":"Islam","year":"2020","journal-title":"Chemosphere"},{"issue":"4","key":"10.1016\/j.etap.2025.104874_bib32","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.neuropharm.2006.05.026","article-title":"Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain","volume":"51","author":"Kindlundh-H\u00f6gberg","year":"2006","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.etap.2025.104874_bib33","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1161\/STROKEAHA.122.035498","article-title":"Ambient air pollution and Stroke: an updated review","volume":"54","author":"Kulick","year":"2023","journal-title":"Stroke"},{"key":"10.1016\/j.etap.2025.104874_bib34","first-page":"153","article-title":"Air quality index and criteria pollutants in ambient atmosphere over selected sites:impact and lessons to learn from COVID-19","author":"Kumar","year":"2021","journal-title":"Environ. Resil. Transform. COVID19"},{"key":"10.1016\/j.etap.2025.104874_bib35","first-page":"1538","article-title":"Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina","volume":"19","author":"Lau","year":"2013","journal-title":"Mol. Vis."},{"key":"10.1016\/j.etap.2025.104874_bib36","series-title":"Bayesian Cognitive Modeling: A Practical Course","author":"Lee","year":"2013"},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib37","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3390\/biom14010035","article-title":"Particulate Matter in Human Elderly: Higher Susceptibility to Cognitive Decline and Age-Related Diseases","volume":"14","author":"L\u00f3pez-Granero","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.etap.2025.104874_bib38","series-title":"Motor activity and movement disorders","first-page":"111","article-title":"Sex differences in rodent spontaneous activity levels","author":"Mead","year":"1996"},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib39","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1159\/000492901","article-title":"Particulate Matter Exposure During Perinatal Life Results in Impaired Glucose Metabolism in Adult Male Rat Offspring","volume":"49","author":"Miranda","year":"2018","journal-title":"Cellular physiology biochemistry international journal experimental cellular physiology biochemistry pharmacology"},{"key":"10.1016\/j.etap.2025.104874_bib40","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.108","article-title":"Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes","volume":"3","author":"Mullin","year":"2013","journal-title":"Transl. Psychiatry"},{"issue":"5","key":"10.1016\/j.etap.2025.104874_bib41","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1002\/mds.28922","article-title":"Air pollution and the risk of parkinson's disease: a review","volume":"37","author":"Murata","year":"2022","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib42","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/npp.2010.88","article-title":"Glutamate receptors in extinction and extinction-based therapies for psychiatric illness","volume":"36","author":"Myers","year":"2011","journal-title":"Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.etap.2025.104874_bib43","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.taap.2018.03.015","article-title":"Early life exposure to air pollution particulate matter (PM) as risk factor for attention deficit\/hyperactivity disorder (ADHD): need for novel strategies for mechanisms and causalities","volume":"354","author":"Myhre","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"25","key":"10.1016\/j.etap.2025.104874_bib44","doi-asserted-by":"crossref","first-page":"25762","DOI":"10.1007\/s11356-019-05825-4","article-title":"Particulate matter in the cultivation area may contaminate leafy vegetables with heavy metals above safe levels in Korea","volume":"26","author":"Noh","year":"2019","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib45","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3233\/JAD-221247","article-title":"Neuropsychiatric symptoms of Alzheimer's DiSease: an Anatomic-genetic Framework for Treatment Development","volume":"95","author":"Nowrangi","year":"2023","journal-title":"J. Alzheimer's. Dis. JAD"},{"key":"10.1016\/j.etap.2025.104874_bib46","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.neuro.2017.10.001","article-title":"Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol","volume":"63","author":"Nway","year":"2017","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.etap.2025.104874_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108971","article-title":"Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner","volume":"191","author":"Oliver","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.etap.2025.104874_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2021.749026","article-title":"From Neurodevelopmental to Neurodegenerative Disorders: The Vascular Continuum","volume":"13","author":"Ouellette","year":"2021","journal-title":"Front. Aging Neurosci."},{"issue":"6","key":"10.1016\/j.etap.2025.104874_bib49","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1080\/15226514.2019.1696744","article-title":"Airborne particulate matter accumulation on common green wall plants","volume":"22","author":"Paull","year":"2020","journal-title":"Int. J. Phytoremediat."},{"key":"10.1016\/j.etap.2025.104874_bib50","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.neuro.2021.07.002","article-title":"Pesticides and aging: preweaning exposure to Chlorpyrifos induces a general hypomotricity state in late-adult rats","volume":"86","author":"Perez-Fernandez","year":"2021","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.etap.2025.104874_bib51","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.psep.2020.07.020","article-title":"Fate of road-dust associated microplastics and per- and polyfluorinated substances in stormwater","volume":"144","author":"Pramanik","year":"2020","journal-title":"Process Saf. Environ. Prot."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib52","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12888-018-1761-4","article-title":"Bayesian alternatives for common null-hypothesis significance tests in psychiatry: a non-technical guide using JASP","volume":"18","author":"Quintana","year":"2018","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.etap.2025.104874_bib53","article-title":"Fruits and vegetables contaminated with particles of heavy metals: a narrative review to explore the use of electromagnetic fields as an alternative treatment method","volume":"9","author":"Rathebe","year":"2023","journal-title":"Cogent Food Agric."},{"issue":"6","key":"10.1016\/j.etap.2025.104874_bib54","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1093\/alcalc\/agp052","article-title":"Sex differences in NMDA receptor expression in human alcoholics","volume":"44","author":"Ridge","year":"2009","journal-title":"Alcohol. Alcohol. (Oxf. Oxfs. )"},{"issue":"5","key":"10.1016\/j.etap.2025.104874_bib55","doi-asserted-by":"crossref","first-page":"57002","DOI":"10.1289\/EHP3169","article-title":"Association between early life exposure to air pollution and working memory and attention","volume":"127","author":"Rivas","year":"2019","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2025.104874_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.139921","article-title":"Toxic metals from atmospheric particulate matter in food species of tomato (Solanum lycopersicum) and strawberry (Fragaria x ananassa) used in urban gardening. A closed chamber study","volume":"340","author":"Rodr\u00edguez-Rodr\u00edguez","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2025.104874_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135538","article-title":"Air quality, health impacts and burden of disease due to air pollution (PM10, PM2.5, NO2 and O3): application of AirQ+ model to the Camp de Tarragona County (Catalonia, Spain)","volume":"703","author":"Rovira","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.etap.2025.104874_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2023.105314","article-title":"Uncovering the link between air pollution and neurodevelopmental alterations during pregnancy and early life exposure: a systematic review","volume":"152","author":"Ruiz-Sobremazas","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"Pt 1","key":"10.1016\/j.etap.2025.104874_bib59","article-title":"Neurodevelopmental consequences of gestational exposure to particulate matter 10: ultrasonic vocalizations and gene expression analysis using a bayesian approach","volume":"240","author":"Ruiz-Sobremazas","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.etap.2025.104874_bib60","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.neuro.2025.04.007","article-title":"The effects of oral gestational particulate matter 10 exposure: insights into neurodevelopmental milestones, inhibitory control, adult sociability, and object recognition","volume":"108","author":"Ruiz-Sobremazas","year":"2025","journal-title":"Neurotoxicology"},{"issue":"2","key":"10.1016\/j.etap.2025.104874_bib61","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/alz.12654","article-title":"Air pollution and dementia in older adults in the Ginkgo Evaluation of Memory Study","volume":"19","author":"Semmens","year":"2023","journal-title":"Alzheimer's. Dement. J. Alzheimer's. Assoc."},{"key":"10.1016\/j.etap.2025.104874_bib62","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2023.1212301","article-title":"Association between air pollution and primary liver cancer in European and east Asian populations: a Mendelian randomization study","volume":"11","author":"Sun","year":"2023","journal-title":"Front. Public Health"},{"issue":"3","key":"10.1016\/j.etap.2025.104874_bib63","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/bcpt.13226","article-title":"Pre-natal brain development as a target for urban air pollution","volume":"125","author":"Sunyer","year":"2019","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"32","key":"10.1016\/j.etap.2025.104874_bib64","doi-asserted-by":"crossref","first-page":"11252","DOI":"10.1523\/JNEUROSCI.1067-15.2015","article-title":"Sex Differences in molecular signaling at inhibitory synapses in the hippocampus","volume":"35","author":"Tabatadze","year":"2015","journal-title":"J. Neuro. offic. J. Soc. Neuro."},{"issue":"Pt 2","key":"10.1016\/j.etap.2025.104874_bib65","article-title":"Air pollution and human cognition: a systematic review and meta-analysis","volume":"859","author":"Thompson","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.etap.2025.104874_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.109686","article-title":"Gestational B-vitamin supplementation alleviates PM 2.5-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring","volume":"185","author":"Wang","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"7","key":"10.1016\/j.etap.2025.104874_bib67","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.3390\/biom13071064","article-title":"Activation of Metabotropic Glutamate Receptor (mGlu2) and Muscarinic Receptors (M1, M4, and M5), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis","volume":"13","author":"Wiero\u0144ska","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.etap.2025.104874_bib68","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3389\/fnins.2015.00524","article-title":"Exposure of BALB\/c mice to diesel engine exhaust origin secondary organic aerosol (DE-SOA) during the developmental stages impairs the social behavior in adult life of the males","volume":"9","author":"Win-Shwe","year":"2016","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib69","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1038\/s41598-022-06769-5","article-title":"Sex-specific differences in KCC2 localisation and inhibitory synaptic transmission in the rat hippocampus","volume":"12","author":"Wolf","year":"2022","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib70","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/s41398-018-0317-1","article-title":"Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits","volume":"8","author":"Woodward","year":"2018","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.etap.2025.104874_bib71","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12868-024-00877-w","article-title":"Changes of brain functional network in Alzheimer's disease and frontotemporal dementia: a graph-theoretic analysis","volume":"25","author":"Wu","year":"2024","journal-title":"BMC Neurosci."},{"issue":"Pt 1","key":"10.1016\/j.etap.2025.104874_bib72","article-title":"Exposure to a real traffic environment impairs brain cognition in aged mice","volume":"215","author":"Xu","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.etap.2025.104874_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128937","article-title":"Air pollution: a culprit of lung cancer","volume":"434","author":"Xue","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"11","key":"10.1016\/j.etap.2025.104874_bib74","doi-asserted-by":"crossref","first-page":"910","DOI":"10.3109\/08958378.2010.494313","article-title":"Pre and post-natal exposure to ambient level of air pollution impairs memory of rats: the role of oxidative stress","volume":"22","author":"Zanchi","year":"2010","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.etap.2025.104874_bib75","doi-asserted-by":"crossref","first-page":"153608","DOI":"10.1016\/j.scitotenv.2022.153608","article-title":"Greenspace exposure and children behavior: A systematic review","volume":"824","author":"Zare Sakhvidi","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.etap.2025.104874_bib76","doi-asserted-by":"crossref","first-page":"e219","DOI":"10.1016\/S2542-5196(22)00001-8","article-title":"Outdoor air pollution exposure and cognitive performance: findings from the enrolment phase of the CONSTANCES cohort","volume":"6","author":"Zare Sakhvidi","year":"2022","journal-title":"Lancet Planet. Health"},{"key":"10.1016\/j.etap.2025.104874_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114962","article-title":"Air pollution weaken your muscle? Evidence from a cross-sectional study on sarcopenia in central China","volume":"258","author":"Zhang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2025.104874_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114425","article-title":"Maternal exposure to PM2.5 induces cognitive impairment in offspring via cerebellar neuroinflammation and oxidative stress","volume":"249","author":"Zhang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2025.104874_bib79","article-title":"Gestational exposure to PM 2.5 leads to cognitive dysfunction in mice offspring via promoting HMGB1-NLRP3 axis mediated hippocampal inflammation","author":"Zhang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf. 223"},{"issue":"JAN","key":"10.1016\/j.etap.2025.104874_bib80","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.3389\/fnins.2018.01000","article-title":"Gestational exposure to particulate matter 2.5 (PM2.5) leads to spatial memory dysfunction and neurodevelopmental impairment in hippocampus of mice offspring","volume":"13","author":"Zheng","year":"2019","journal-title":"Front. Neurosci."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925002492?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668925002492?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T13:11:13Z","timestamp":1773839473000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668925002492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":80,"alternative-id":["S1382668925002492"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2025.104874","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term impact of oral gestational PM10 exposure on morris water maze performance and hippocampal gene expression","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2025.104874","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104874"}}