{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T23:09:36Z","timestamp":1774652976835,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental and Toxicologic Pathology"],"published-print":{"date-parts":[[2005,4]]},"DOI":"10.1016\/j.etp.2005.01.001","type":"journal-article","created":{"date-parts":[[2005,8,18]],"date-time":"2005-08-18T11:37:07Z","timestamp":1124365027000},"page":"385-392","source":"Crossref","is-referenced-by-count":67,"title":["Effect of Aronia melanocarpa fruit juice on indomethacin-induced gastric mucosal damage and oxidative stress in rats"],"prefix":"10.1016","volume":"56","author":[{"given":"S.","family":"Valcheva-Kuzmanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Marazova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Krasnaliev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Galunska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Borisova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Belcheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etp.2005.01.001_bib1","first-page":"161","article-title":"Antiulcerogenic activity of flavonoids and gastric protection","volume":"42","author":"Alarcon","year":"1994","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.etp.2005.01.001_bib2","first-page":"697","article-title":"Effects of flavonoids on parietal cell acid secretion, gastric mucosal prostaglandin production and Helicobacter pylori growth","volume":"45","author":"Beil","year":"1995","journal-title":"Arzneim Forsch"},{"key":"10.1016\/j.etp.2005.01.001_bib3","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.1021\/jf0255735","article-title":"Studies on antioxidant activities of pomegranate (Punica granatum) peel extract using in vivo models","volume":"50","author":"Chidambara Murthy","year":"2002","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.etp.2005.01.001_bib4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF00936440","article-title":"Effect of stress on the antioxidant enzymes and gastric ulceration","volume":"125","author":"Das","year":"1993","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.etp.2005.01.001_bib5","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/gut.35.2.179","article-title":"Helocobacter pylori stimulates antral mucosal reactive metabolite production in vivo","volume":"35","author":"Davis","year":"1994","journal-title":"Gut"},{"key":"10.1016\/j.etp.2005.01.001_bib6","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/labinvest.3780124","article-title":"Gastric mucosal cell proliferation in ethanol-induced chronic mucosal injury is related to oxidative stress and lipid peroxidation in rats","volume":"80","author":"Hernandez-Munoz","year":"2000","journal-title":"Lab Invest"},{"key":"10.1016\/j.etp.2005.01.001_bib7","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/0003-2697(76)90326-2","article-title":"A fluorimetric method for determination of oxidized and reduced glutathione in tissues","volume":"74","author":"Hissin","year":"1986","journal-title":"Annal Biochem"},{"key":"10.1016\/j.etp.2005.01.001_bib8","first-page":"545","article-title":"Antiulcerogenic effect of some gastrointestinally acting plant extracts and their combination","volume":"51","author":"Khayyal","year":"2001","journal-title":"Arzneim Forsch"},{"key":"10.1016\/j.etp.2005.01.001_bib9","first-page":"332","article-title":"Anthocyanins\u2014an adjunct to cardiovascular therapy?","volume":"57","author":"Kowalczyk","year":"2002","journal-title":"Kadiologia Polska"},{"key":"10.1016\/j.etp.2005.01.001_bib10","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0378-8741(99)00174-9","article-title":"Evidence of protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions","volume":"71","author":"La Casa","year":"2000","journal-title":"J Ethnopharamacol"},{"key":"10.1016\/j.etp.2005.01.001_bib11","first-page":"95","article-title":"Anti-ulcer activity of an anthocyanidin from Vaccinium myrtillus (bilberry) fruits and cell cultures","volume":"131","author":"Magistretti","year":"1988","journal-title":"Plant Sci"},{"key":"10.1016\/j.etp.2005.01.001_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1515\/znc-1998-1-215","article-title":"Anti-oxidant mechanisms involved in gastroprotective effects of quercetin","volume":"53","author":"Martin","year":"1998","journal-title":"Z Naturforsch [C]"},{"key":"10.1016\/j.etp.2005.01.001_bib13","first-page":"30S","article-title":"Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury","volume":"43","author":"Naito","year":"1998","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.etp.2005.01.001_bib14","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1021\/jf0108765","article-title":"Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin","volume":"50","author":"Noda","year":"2002","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.etp.2005.01.001_bib15","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1111\/j.1365-2621.1988.tb13577.x","article-title":"Anthocyanins in fruits of Aronia Melanocarpa (Chokeberry)","volume":"53","author":"Oszmia\u0144ski","year":"1988","journal-title":"J Food Sci"},{"key":"10.1016\/j.etp.2005.01.001_bib16","first-page":"415","article-title":"The gastric anti-ulcer activity of naringenin, a specific histidine decarbohylase inhibitor","volume":"4","author":"Parmar","year":"1983","journal-title":"Int J Tissue React"},{"key":"10.1016\/j.etp.2005.01.001_bib17","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/0306-3623(94)90217-8","article-title":"Prevention by rutin of gastric lesions induced by ethanol in rats: role of endogenous prostaglandins","volume":"25","author":"Perez-Guerrero","year":"1994","journal-title":"Gen Pharmacol"},{"key":"10.1016\/j.etp.2005.01.001_bib18","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/BF01296666","article-title":"Free radicals and lipid peroxidation in ethanol- and aspirin-induced gastric mucosal injury","volume":"32","author":"Pihan","year":"1987","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.etp.2005.01.001_bib19","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/0005-2760(76)90247-2","article-title":"Cyclic peroxidase and thiobarbituric assay","volume":"441","author":"Porter","year":"1976","journal-title":"Biochem Biophys Acta"},{"key":"10.1016\/j.etp.2005.01.001_bib20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3923\/pjn.2002.89.92","article-title":"Tocotrienol-rich fraction and its effects on parameters affecting gastric mucosal integrity after a single exposure to indomethacin","volume":"1","author":"Saad","year":"2002","journal-title":"Pakistan J Nutr"},{"key":"10.1016\/j.etp.2005.01.001_bib21","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1136\/gut.33.2.164","article-title":"Mucosal adaptation to indomethacin induced gastric damage in man\u2014studies on morphology, blood flow and prostaglandin E2 metabolism","volume":"33","author":"Shorrock","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.etp.2005.01.001_bib22","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1248\/bpb.16.29","article-title":"Role of lipid peroxidation in gastric mucosal lesions induced by ischemia-reperfusion in the pylorus-ligated rat","volume":"16","author":"Tanaka","year":"1993","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.etp.2005.01.001_bib23","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1248\/bpb.19.716","article-title":"Lipid peroxidation in gastric mucosal lesions induced by indomethacin in rat","volume":"19","author":"Tanaka","year":"1996","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.etp.2005.01.001_bib24","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/0006-2952(96)00421-2","article-title":"Inhibition of lipid peroxidation and the active oxygen radical scavenging effect of anthocyanin pigments isolated from Phaseolus vulgaris L","volume":"52","author":"Tsuda","year":"1996","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.etp.2005.01.001_bib25","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1021\/np980501m","article-title":"Antioxidant and anti-inflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries","volume":"62","author":"Wang","year":"1999","journal-title":"J Nat Prod"},{"key":"10.1016\/j.etp.2005.01.001_bib26","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0016-5085(81)90196-7","article-title":"Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis and the gastrointestinal damage induced by indomethacin in the rat","volume":"80","author":"Whittle","year":"1981","journal-title":"Gastroenterol"},{"issue":"Suppl 1","key":"10.1016\/j.etp.2005.01.001_bib27","first-page":"35S","article-title":"The defensive role played by the gastric microcirculation","volume":"11","author":"Whittle","year":"1989","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"10.1016\/j.etp.2005.01.001_bib28","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/abbi.1996.0331","article-title":"Bleaching of the red anthocyanin induced by superoxide radical","volume":"332","author":"Yamasaki","year":"1996","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.etp.2005.01.001_bib29","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1136\/gut.34.6.732","article-title":"Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats","volume":"34","author":"Yoshikawa","year":"1993","journal-title":"Gut"},{"key":"10.1016\/j.etp.2005.01.001_bib30","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1021\/jf020728u","article-title":"Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries","volume":"51","author":"Zheng","year":"2003","journal-title":"J Agric Food Chem"}],"container-title":["Experimental and Toxicologic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940299305000047?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940299305000047?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T02:11:43Z","timestamp":1586398303000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0940299305000047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["S0940299305000047"],"URL":"https:\/\/doi.org\/10.1016\/j.etp.2005.01.001","relation":{},"ISSN":["0940-2993"],"issn-type":[{"value":"0940-2993","type":"print"}],"subject":[],"published":{"date-parts":[[2005,4]]}}}