{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:41:03Z","timestamp":1790516463634,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental and Toxicologic Pathology"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1016\/j.etp.2010.09.010","type":"journal-article","created":{"date-parts":[[2010,11,12]],"date-time":"2010-11-12T12:09:59Z","timestamp":1289563799000},"page":"357-365","source":"Crossref","is-referenced-by-count":71,"title":["Involvement of oxidative stress in taxol-induced apoptosis in chronic myelogenous leukemia K562 cells"],"prefix":"10.1016","volume":"64","author":[{"given":"Azadeh","family":"Meshkini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razieh","family":"Yazdanparast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.etp.2010.09.010_bib0005","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.tiv.2008.02.010","article-title":"2-Deoxy-d-ribose-induced oxidative stress causes apoptosis in human monocytic cells: prevention by pyridoxal-5\u2032-phosphate","volume":"22","author":"Ardestani","year":"2008","journal-title":"Toxicol In Vitro"},{"key":"10.1016\/j.etp.2010.09.010_bib0010","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0163-7258(91)90044-M","article-title":"The role of glutathione-dependent enzymes in drug resistance","volume":"51","author":"Black","year":"1991","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.etp.2010.09.010_bib0015","first-page":"130","article-title":"Raf-1\/bcl-2 phosphorylation: a step from microtubule damage to cell death","volume":"57","author":"Blgosklonny","year":"1997","journal-title":"Cancer Res"},{"key":"10.1016\/j.etp.2010.09.010_bib0020","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.canlet.2004.03.047","article-title":"Comparison of burst of reactive oxygen species and activation of caspase-3 in apoptosis of K562 and HL-60 cells induced by docetaxel","volume":"214","author":"Cao","year":"2004","journal-title":"Cancer Lett"},{"key":"10.1016\/j.etp.2010.09.010_bib0025","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0092-8674(00)00116-1","article-title":"Signal transduction by the JNK group of MAP kinases","volume":"103","author":"Davis","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.etp.2010.09.010_bib0030","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1038\/sj.onc.1206280","article-title":"Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3\/-8-driven mitochondrial amplification loop","volume":"22","author":"Haefen","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.etp.2010.09.010_bib0035","first-page":"1253","article-title":"Taxol induces bcl-2 phosphorylation and death of prostate cancer cells","volume":"56","author":"Haldar","year":"1996","journal-title":"Cancer Res"},{"key":"10.1016\/j.etp.2010.09.010_bib0040","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1042\/bst0290345","article-title":"Role of reactive oxygen species in cell signalling pathways","volume":"29","author":"Hancock","year":"2001","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.etp.2010.09.010_bib0045","doi-asserted-by":"crossref","first-page":"5418","DOI":"10.1093\/emboj\/19.20.5418","article-title":"MAPK\/ERK signaling in activated T cells inhibits CD95\/Fas-mediated apoptosis downstream of DISC assembly","volume":"19","author":"Holmstorm","year":"2000","journal-title":"EMBO J"},{"key":"10.1016\/j.etp.2010.09.010_bib0050","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1126\/science.1072682","article-title":"Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases","volume":"298","author":"Johnson","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.etp.2010.09.010_bib0055","doi-asserted-by":"crossref","first-page":"9679","DOI":"10.1073\/pnas.94.18.9679","article-title":"p53-independent apoptosis induced by paclitaxel through an indirect mechanism","volume":"94","author":"Lanni","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.etp.2010.09.010_bib0060","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1016\/j.etp.2010.09.010_bib0065","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/j.tiv.2008.05.005","article-title":"Involvement of ERK\/MAPK pathway in megakaryocytic differentiation of K562cells induced by 3-hydrogenkwadaphnin","volume":"22","author":"Meshkini","year":"2008","journal-title":"Toxicol In Vitro"},{"key":"10.1016\/j.etp.2010.09.010_bib0070","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1093\/jnci\/88.18.1308","article-title":"Relationship of mitotic arrest and apoptosis to antitumor effect of paclitaxel","volume":"88","author":"Milross","year":"1996","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.etp.2010.09.010_bib0075","doi-asserted-by":"crossref","first-page":"3896","DOI":"10.1073\/pnas.95.7.3896","article-title":"Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis","volume":"95","author":"Moos","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.etp.2010.09.010_bib0080","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/sj.cdd.4401012","article-title":"Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent","volume":"9","author":"Ofir","year":"2002","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.etp.2010.09.010_bib0085","doi-asserted-by":"crossref","first-page":"51057","DOI":"10.1074\/jbc.M406543200","article-title":"Taxol induces caspase-10-dependent apoptosis","volume":"279","author":"Park","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.etp.2010.09.010_bib0090","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1074\/jbc.M011565200","article-title":"Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3","volume":"276","author":"Paroni","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.etp.2010.09.010_bib0095","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1006\/bbrc.2000.3877","article-title":"Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38 gamma in human melanoma cells","volume":"278","author":"Pillaire","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.etp.2010.09.010_bib0100","first-page":"1111","article-title":"High Raf-1 kinase activity protects human tumor cells against paclitaxel-induced cytotoxicity","volume":"4","author":"Rasouli-Nia","year":"1998","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.etp.2010.09.010_bib0105","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1146\/annurev.med.48.1.353","article-title":"The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents","volume":"48","author":"Rowinsky","year":"1997","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.etp.2010.09.010_bib0110","doi-asserted-by":"crossref","first-page":"31108","DOI":"10.1074\/jbc.274.43.31108","article-title":"Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK\/Erk kinase","volume":"274","author":"Scheid","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.etp.2010.09.010_bib0115","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1006\/excr.2001.5262","article-title":"The role of ERK 1\/2 and p38 MAP-Kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells","volume":"268","author":"Seidman","year":"2001","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.etp.2010.09.010_bib0120","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cellsig.2007.10.015","article-title":"Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2","volume":"20","author":"Selimovic","year":"2008","journal-title":"Cell Signal"},{"key":"10.1016\/j.etp.2010.09.010_bib0125","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/sj.onc.1202305","article-title":"Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells","volume":"18","author":"Shtill","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.etp.2010.09.010_bib0130","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1083\/jcb.135.3.689","article-title":"Differential taxol-dependent arrest of transformed and nontransformed cells in the G1 phase of the cell cycle, and specific-related mortality of transformed cells","volume":"135","author":"Trielli","year":"1996","journal-title":"J Cell Biol"},{"key":"10.1016\/j.etp.2010.09.010_bib0135","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S0891-5849(01)00616-5","article-title":"Direct effect of taxol on free radical formation and mitochondrial permeability transition","volume":"31","author":"Varbiro","year":"2001","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.etp.2010.09.010_bib0140","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1002\/1097-0142(20000601)88:11<2619::AID-CNCR26>3.0.CO;2-J","article-title":"Paclitaxel-induced cell death: where the cell cycle and apoptosis come together","volume":"88","author":"Wang","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.etp.2010.09.010_bib0145","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s00280-004-0831-0","article-title":"Involvement of oxidative stress and caspase activation in paclitaxel-induced apoptosis of primary effusion lymphoma cells","volume":"54","author":"Wang","year":"2004","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1016\/j.etp.2010.09.010_bib0150","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0092-8674(94)90422-7","article-title":"Ich-1, an Ice\/ced-3-related gene, encodes both positive and negative regulators of programmed cell death","volume":"78","author":"Wang","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.etp.2010.09.010_bib0160","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.leukres.2007.06.006","article-title":"NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells","volume":"32","author":"Wang","year":"2008","journal-title":"Leuk Res"},{"key":"10.1016\/j.etp.2010.09.010_bib0155","article-title":"The involvement of ROS overproduction and mitochondrial dysfunction in PBDE-47-induced apoptosis on Jurkat cells","author":"Yun","year":"2010","journal-title":"Exp Taxicol Pathol"}],"container-title":["Experimental and Toxicologic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940299310001624?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940299310001624?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T12:58:51Z","timestamp":1636808331000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0940299310001624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["S0940299310001624"],"URL":"https:\/\/doi.org\/10.1016\/j.etp.2010.09.010","relation":{},"ISSN":["0940-2993"],"issn-type":[{"value":"0940-2993","type":"print"}],"subject":[],"published":{"date-parts":[[2012,5]]}}}