{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:00:25Z","timestamp":1761663625961},"reference-count":37,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental and Toxicologic Pathology"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.etp.2017.06.002","type":"journal-article","created":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T16:16:21Z","timestamp":1498148181000},"page":"643-648","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effects of retinoic acid on mmp-2 production, proliferation and ultrastructural morphology in rat uterus"],"prefix":"10.1016","volume":"69","author":[{"given":"Tu\u011fba","family":"Kotil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eeng\u00fcl","family":"\u015eent\u00fcrk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00fcrkan","family":"Sario\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leyla","family":"Tapul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etp.2017.06.002_bib0005","series-title":"Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal","first-page":"31","author":"Ayala","year":"2014"},{"issue":"4","key":"10.1016\/j.etp.2017.06.002_bib0010","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.1365-2559.2011.03954.x","article-title":"An easy cell counting method for immunohistochemistry that does not use an image analysis program","volume":"59","author":"Bologna-Molina","year":"2011","journal-title":"Histopathology"},{"issue":"5","key":"10.1016\/j.etp.2017.06.002_bib0015","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0891-5849(02)00959-0","article-title":"Lipofuscin: mechanisms of age-related accumulation and influence on cell function","volume":"33","author":"Brunk","year":"2002","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.etp.2017.06.002_bib0020","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1530\/JME-10-0064","article-title":"Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms","volume":"46","author":"Cheng","year":"2011","journal-title":"J. Mol. Endocrinol."},{"issue":"4","key":"10.1016\/j.etp.2017.06.002_bib0025","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1210\/er.2002-0005","article-title":"The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle","volume":"24","author":"Curry","year":"2003","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.etp.2017.06.002_bib0030","first-page":"3521","article-title":"Expression of metalloproteinases MMP-2 and MMP-9 in sentinel lymph node and serum of patients with metastatic and non-Metastatic Breast cancer","volume":"30","author":"Dan\u0131ele","year":"2010","journal-title":"Ant\u0131cancer Res."},{"issue":"3","key":"10.1016\/j.etp.2017.06.002_bib0035","first-page":"295","article-title":"Generation of radical oxygen species by neural crest cells treated in vitro with isotretinoin and 4-oxo-isotretinoin","volume":"10","author":"Davis","year":"1990","journal-title":"J. Craniofacial Gen. Devel. Biol."},{"key":"10.1016\/j.etp.2017.06.002_bib0040","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1002\/cncr.10355","article-title":"Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion","volume":"94","author":"Di Nezza","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.etp.2017.06.002_bib0045","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1006\/excr.2001.5412","article-title":"Retinoic acid inhibits telomerase activity and downregulates expression but does not affect splicing of hTERT: correlation with cell growth rate inhibition in an in vitro cervical carcinogenesis\/Multidrug-Resistance model","volume":"272","author":"Ding","year":"2002","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.etp.2017.06.002_bib0050","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1095\/biolreprod.103.015933","article-title":"Expression pattern of metalloproteinases and tissue inhibitors of matrix-metalloproteinases in cycling human endometrium","volume":"69","author":"Goffin","year":"2003","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.etp.2017.06.002_bib0055","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1093\/annonc\/mdj129","article-title":"Metalloproteinase-2, \u22127 and \u22129 and tissue inhibitorof metalloproteinase-1 and \u22122 expression in normal, hyperplastic and neoplastic endometrium: a clinical-pathological correlation study","volume":"17","author":"Graesslin","year":"2006","journal-title":"Annals Oncol."},{"key":"10.1016\/j.etp.2017.06.002_bib0060","doi-asserted-by":"crossref","first-page":"G1178","DOI":"10.1152\/ajpgi.00295.2007","article-title":"Effect of retinoic acid on cell proliferation and differentiation as well as on lipid synthesis lipoprotein secretion, and apolipoprotein biogenesis","volume":"293","author":"Grenier","year":"2007","journal-title":"Am. J. Physiol. Gastrointest Liver Physiol."},{"key":"10.1016\/j.etp.2017.06.002_bib0065","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1095\/biolreprod51.3.509","article-title":"NKR-P1+ cells in the rat uterus: granulated metrial gland cells are of the NaturalKiller cell lineage","volume":"51","author":"Head","year":"1994","journal-title":"B\u0131ol. Reprod."},{"issue":"2","key":"10.1016\/j.etp.2017.06.002_bib0070","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0041-008X(79)90331-4","article-title":"Comparative subchronic toxicity of all-trans- and 13-cis-retinoic acid in Sprague-Dawley rats","volume":"47","author":"Hixson","year":"1979","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.etp.2017.06.002_bib0075","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1182\/blood-2010-01-261040","article-title":"Autophagy contributes to therapy-induced degradation of the PML\/RARAoncoprotein","volume":"116","author":"Isakson","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.etp.2017.06.002_bib0080","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1167\/iovs.06-0549","article-title":"Effects of lipid peroxidation-Related protein modifications on RPE lysosomal functions and POS phagocytosis","volume":"48","author":"Kaemmerer","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.etp.2017.06.002_bib0085","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S0190-9622(82)70054-4","article-title":"Toxicology carcinogenicity, and teratogenicity of some orally administered retinoids","volume":"6","author":"Kamm","year":"1982","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.etp.2017.06.002_bib0090","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.exer.2009.12.011","article-title":"Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells","volume":"90","author":"Krohne","year":"2010","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.etp.2017.06.002_bib0095","first-page":"245","article-title":"Light microscopic studies of spermatogenesis in rats following the administration of a high dose of 13-cis-retinoic acid","volume":"60","author":"Kuhlwein","year":"1985","journal-title":"Z. Hautkr."},{"issue":"10","key":"10.1016\/j.etp.2017.06.002_bib0100","doi-asserted-by":"crossref","first-page":"4756","DOI":"10.1210\/en.2004-0514","article-title":"Estrogen directly induces expression of retinoic acid biosynthetic enzymes, compartmentalized between the epithelium and underlying stromal cells in rat uterus","volume":"145","author":"Li","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.etp.2017.06.002_bib0105","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s004280000286","article-title":"Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas","volume":"438","author":"Maeta","year":"2001","journal-title":"Virchows Arch."},{"key":"10.1016\/j.etp.2017.06.002_bib0110","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1365-2265.2008.03207.x","article-title":"Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells","volume":"69","author":"Malik","year":"2008","journal-title":"Clinical Endocrinol."},{"key":"10.1016\/j.etp.2017.06.002_bib0115","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1110\/ps.062430706","article-title":"Enzymatic processing of collagen IV by MMP-2 (gelatinase A) affects neutrophil migration and it is modulated by extracatalytic domains","volume":"15","author":"Monaco","year":"2006","journal-title":"Protein Sci."},{"key":"10.1016\/j.etp.2017.06.002_bib0120","doi-asserted-by":"crossref","first-page":"78","DOI":"10.2741\/938","article-title":"Progesterone action in the human endometrium: induction of a unique tissue environment which limits matrix metalloproteinase (MMP) expression","volume":"8","author":"Osteen","year":"2003","journal-title":"Fron. Biosci."},{"key":"10.1016\/j.etp.2017.06.002_bib0125","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.micpath.2007.11.004","article-title":"Retinoic acid inhibits the infectivity and growth of Chlamydia pneumoniae in epithelial and endothelial cells through different receptors","volume":"44","author":"Puolakkainen","year":"2008","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.etp.2017.06.002_bib0130","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/humrep\/den348","article-title":"Uterine natural killer cells and angiogenesis in recurrent reproductive failure","volume":"24","author":"Quenby","year":"2009","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.etp.2017.06.002_bib0135","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.4161\/auto.6.8.13793","article-title":"Autophagy: a target for retinoic acids","volume":"6","author":"Rajawat","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.etp.2017.06.002_bib0140","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1089\/ars.2010.3491","article-title":"Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor","volume":"14","author":"Rajawat","year":"2011","journal-title":"Antioxid. Redox Signal."},{"issue":"2010","key":"10.1016\/j.etp.2017.06.002_bib0145","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbamcr.2009.09.015","article-title":"Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics","volume":"1803","author":"Rodr\u00edguez","year":"2010","journal-title":"Biochimica. et Biophysica. Acta"},{"key":"10.1016\/j.etp.2017.06.002_bib0150","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1096\/fasebj.10.9.8801180","article-title":"Vitamin A and retinoids in antiviralresponses","volume":"10","author":"Ross","year":"1996","journal-title":"FASEB J."},{"key":"10.1016\/j.etp.2017.06.002_bib0155","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1476-4598-5-13","article-title":"In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer","volume":"5","author":"Saidi","year":"2006","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.etp.2017.06.002_bib0160","first-page":"673","article-title":"Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary","volume":"17","author":"Sakata","year":"2000","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.etp.2017.06.002_bib0165","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/nri3065","article-title":"Organ-specific features of natural killer cells","volume":"11","author":"Shi","year":"2011","journal-title":"Nature Reviews immunol."},{"key":"10.1016\/j.etp.2017.06.002_bib0170","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.exer.2005.01.007","article-title":"RPE lipofuscin and its role in retinal pathobiology Exp","volume":"80","author":"Sparrow","year":"2005","journal-title":"Eye Res."},{"issue":"3","key":"10.1016\/j.etp.2017.06.002_bib0175","first-page":"265","article-title":"Retinoic acid-induced Golgi apparatus disruption in F2000 fibroblasts: a model for enhanced intracellular retrograde transport","volume":"36","author":"Tzankov","year":"2003","journal-title":"J. Biochem. Mol. Biol."},{"key":"10.1016\/j.etp.2017.06.002_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/cmi.2010.38","article-title":"Natural killer cell triggered vascular transformation: maternal care before birth?","volume":"8","author":"Zhang","year":"2010","journal-title":"Cell Mol. Immunol."},{"key":"10.1016\/j.etp.2017.06.002_bib0185","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1210\/endo.141.2.7323","article-title":"Retinoic acid synthesis and expression of cellular retinol-binding protein and cellular retinoic acid- binding protein type II are concurrent with decidualization of rat uterine stromal cells","volume":"141","author":"Zheng","year":"2000","journal-title":"Endocrinology"}],"container-title":["Experimental and Toxicologic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940299316302615?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0940299316302615?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T11:55:39Z","timestamp":1569498939000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0940299316302615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0940299316302615"],"URL":"https:\/\/doi.org\/10.1016\/j.etp.2017.06.002","relation":{},"ISSN":["0940-2993"],"issn-type":[{"value":"0940-2993","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of retinoic acid on mmp-2 production, proliferation and ultrastructural morphology in rat uterus","name":"articletitle","label":"Article Title"},{"value":"Experimental and Toxicologic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etp.2017.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}