{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:49:51Z","timestamp":1755218991398,"version":"3.43.0"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:00:00Z","timestamp":1747353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology Case Reports"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.eucr.2025.103071","type":"journal-article","created":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T02:18:23Z","timestamp":1747448303000},"page":"103071","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Unilateral pubic hair growth: a paracrine finding indicative of underlying leydig cell tumor in a prepubertal boy"],"prefix":"10.1016","volume":"61","author":[{"given":"Gabriel","family":"van de Walle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8965-6414","authenticated-orcid":false,"given":"Luca A.","family":"Morgantini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bronwyn G.","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoleta C.","family":"Arva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiana","family":"Hentea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia C.","family":"Boucher Berry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Osta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilie K.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6 Part 1","key":"10.1016\/j.eucr.2025.103071_bib1","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1097\/01.ju.0000144402.13556.74","article-title":"Prepubertal testis tumors: actual prevalence rate of histological types","volume":"172","author":"Pohl","year":"2004","journal-title":"J Urol"},{"issue":"5","key":"10.1016\/j.eucr.2025.103071_bib2","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S1470-2045(10)70012-7","article-title":"Testicular and paratesticular tumours in the prepubertal population","volume":"11","author":"Ahmed","year":"2010","journal-title":"Lancet Oncol"},{"issue":"12","key":"10.1016\/j.eucr.2025.103071_bib3","article-title":"Precocious puberty associated with testicular hormone-secreting Leydig cell tumor","volume":"11","author":"Alagha","year":"2019","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.eucr.2025.103071_bib4","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1148\/rg.231025133","article-title":"From the archives of the AFIP: extratesticular scrotal masses: radiologic-pathologic correlation","volume":"23","author":"Woodward","year":"2003","journal-title":"Radiographics"},{"issue":"2","key":"10.1016\/j.eucr.2025.103071_bib5","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ucl.2007.02.003","article-title":"Timely diagnosis of testicular cancer","volume":"34","author":"Moul","year":"2007","journal-title":"Urol Clin"},{"key":"10.1016\/j.eucr.2025.103071_bib6","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1002\/cncr.1980.45.s7.1755","article-title":"The role of biologic tumor markers in testicular cancer","volume":"45","author":"Javadpour","year":"1980","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.eucr.2025.103071_bib7","article-title":"Leydig cell tumor-induced gonadotropin-independent precocious puberty progressing to gonadotropin-dependent precocious puberty post orchiectomy: out of the frying Pan into the fire","volume":"14","author":"Singhania","year":"2022","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.eucr.2025.103071_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpurol.2020.10.015","article-title":"Spermatogenesis in pre-pubertal boys with Leydig cell neoplasms suggests paracrine stimulation by testosterone","volume":"17","author":"Keefe","year":"2021","journal-title":"J Pediatr Urol"},{"issue":"3","key":"10.1016\/j.eucr.2025.103071_bib9","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S2213-8587(15)00380-0","article-title":"Causes, diagnosis, and treatment of central precocious puberty","volume":"4","author":"Latronico","year":"2016","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"15","key":"10.1016\/j.eucr.2025.103071_bib10","doi-asserted-by":"crossref","first-page":"3652","DOI":"10.3390\/cancers14153652","article-title":"Leydig cell tumors of the testis: an update of the imaging characteristics of a not so rare lesion","volume":"14","author":"Maxwell","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.eucr.2025.103071_bib11","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ijscr.2017.03.043","article-title":"Leydig cell tumor in grey zone: a case report","volume":"35","author":"Muheilan","year":"2017","journal-title":"Int J Surg Case Rep"},{"issue":"2","key":"10.1016\/j.eucr.2025.103071_bib12a","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/JU.0000000000000318","article-title":"Diagnosis and treatment of early stage testicular cancer: AUA guideline","volume":"202","author":"Stephenson","year":"2019","journal-title":"J Urol"},{"issue":"3","key":"10.1016\/j.eucr.2025.103071_bib12b","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S2213-8587(15)00380-0","article-title":"Causes, diagnosis, and treatment of central precocious puberty","volume":"4","author":"Latronico","year":"2016","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"8","key":"10.1016\/j.eucr.2025.103071_bib13","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1093\/humrep\/dez083","article-title":"Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study","volume":"34","author":"Pozza","year":"2019","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.eucr.2025.103071_bib14","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1097\/MPH.0000000000001124","article-title":"A multicenter retrospective review of pediatric Leydig cell tumor of the testis","volume":"41","author":"Luckie","year":"2019","journal-title":"J Pediatr Hematol Oncol"},{"issue":"5","key":"10.1016\/j.eucr.2025.103071_bib15","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1097\/JU.0000000000000705","article-title":"Risk factors and treatment outcomes of 1,375 patients with testicular Leydig cell tumors: analysis of published case series data","volume":"203","author":"Fankhauser","year":"2020","journal-title":"J Urol"}],"container-title":["Urology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214442025001421?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214442025001421?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T15:12:58Z","timestamp":1754493178000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214442025001421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":16,"alternative-id":["S2214442025001421"],"URL":"https:\/\/doi.org\/10.1016\/j.eucr.2025.103071","relation":{},"ISSN":["2214-4420"],"issn-type":[{"type":"print","value":"2214-4420"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unilateral pubic hair growth: a paracrine finding indicative of underlying leydig cell tumor in a prepubertal boy","name":"articletitle","label":"Article Title"},{"value":"Urology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eucr.2025.103071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"103071"}}