{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T16:15:51Z","timestamp":1778861751359,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology Case Reports"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.eucr.2025.103251","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:18:13Z","timestamp":1761128293000},"page":"103251","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Bilateral testicular atrophy and hypogonadism induced by paratesticular leiomyosarcoma and untreated cryptorchidism"],"prefix":"10.1016","volume":"63","author":[{"given":"Daniel A.","family":"Arreola-Ram\u00edrez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alec","family":"Anceno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Fern\u00e1ndez Varela-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy B.","family":"Guzm\u00e1n-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Haddad-Serv\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaromin","family":"Mu\u00f1oz-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9sar A.","family":"Silva-Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro A.","family":"Alvarado-Bahena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Cervantes-Zorrilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 H.","family":"Ch\u00e1vez-Fraga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo E.","family":"Dom\u00ednguez-Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrey","family":"Ram\u00edrez-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eucr.2025.103251_bib1","doi-asserted-by":"crossref","DOI":"10.1177\/1534735419900554","article-title":"Paratesticular mesenchymal malignancies: a single-center case series, clinical management, and review of literature","volume":"19","author":"Gatto","year":"2020","journal-title":"Integr Cancer Ther"},{"issue":"9","key":"10.1016\/j.eucr.2025.103251_bib2","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1097\/00000478-200109000-00004","article-title":"Leiomyosarcoma of the paratesticular region: a clinicopathologic study","volume":"25","author":"Fisher","year":"2001","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"10.1016\/j.eucr.2025.103251_bib3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12957-022-02539-9","article-title":"Leiomyosarcoma of the spermatic cord: a rare paratesticular neoplasm case report","volume":"20","author":"Ahmed","year":"2022","journal-title":"World J Surg Oncol"},{"issue":"1","key":"10.1016\/j.eucr.2025.103251_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12885-021-09122-7","article-title":"Optimal surgical treatment for paratesticular leiomyosarcoma: retrospective analysis of 217 reported cases","volume":"22","author":"Kamitani","year":"2022","journal-title":"BMC Cancer"},{"issue":"2","key":"10.1016\/j.eucr.2025.103251_bib5","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00261-016-0870-0","article-title":"Review of paratesticular pathology: findings on ultrasound and MRI","volume":"42","author":"Nicola","year":"2017","journal-title":"Abdom Radiol (NY)"},{"key":"10.1016\/j.eucr.2025.103251_bib6","series-title":"N Engl J Med","first-page":"2005","article-title":"Testicular cancer--discoveries and updates","author":"Hanna","year":"2014"},{"key":"10.1016\/j.eucr.2025.103251_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1305428","article-title":"The fate of germ cells in cryptorchid testis","volume":"14","author":"Thorup","year":"2024","journal-title":"Front Endocrinol"},{"issue":"7","key":"10.1016\/j.eucr.2025.103251_bib8","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.jpedsurg.2019.06.023","article-title":"Cryptorchidism, gonocyte development, and the risks of germ cell malignancy and infertility: a systematic review","volume":"55","author":"Loebenstein","year":"2020","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.eucr.2025.103251_bib9","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3389\/fendo.2014.00063","article-title":"Spermatogenesis and cryptorchidism","volume":"5","author":"Cobellis","year":"2014","journal-title":"Front Endocrinol"},{"issue":"10","key":"10.1016\/j.eucr.2025.103251_bib10","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S2352-4642(18)30254-2","article-title":"Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 years","volume":"2","author":"Schneuer","year":"2018","journal-title":"Lancet Child Adolesc Health"},{"issue":"2","key":"10.1016\/j.eucr.2025.103251_bib11","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.juro.2008.10.074","article-title":"Cryptorchidism and testicular cancer: separating fact from fiction","volume":"181","author":"Wood","year":"2009","journal-title":"J Urol"},{"issue":"5","key":"10.1016\/j.eucr.2025.103251_bib12","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1210\/jc.2018-00229","article-title":"Testosterone therapy in men with hypogonadism: an Endocrine society clinical practice guideline","volume":"103","author":"Bhasin","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.eucr.2025.103251_bib13","article-title":"Case report: effect of testicular adenomatoid tumors on testicular endocrine function in children","volume":"16","author":"Li","year":"2025","journal-title":"Front Endocrinol"},{"issue":"Pt 5","key":"10.1016\/j.eucr.2025.103251_bib14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1258\/acb.2011.011236","article-title":"Hypergonadotrophic hypogonadism due to testicular adrenal rest tumours presenting with hypogonadotrophic hypergonadism","volume":"49","author":"Ashby","year":"2012","journal-title":"Ann Clin Biochem"},{"issue":"13","key":"10.1016\/j.eucr.2025.103251_bib15","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1056\/NEJMra1909786","article-title":"Congenital adrenal hyperplasia due to 21-Hydroxylase deficiency","volume":"383","author":"Merke","year":"2020","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.eucr.2025.103251_bib16","first-page":"757","article-title":"Simultaneously detected bilateral testicular cancer of different histopathological origin--a challenging situation for the urologist","volume":"24","author":"Hammerich","year":"2010","journal-title":"Oncology (Williston Park)"},{"issue":"6","key":"10.1016\/j.eucr.2025.103251_bib17","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/S0022-5347(17)57007-X","article-title":"Paratesticular rhabdomyosarcomas and leiomyosarcomas: a clinicopathological review","volume":"121","author":"Banik","year":"1979","journal-title":"J Urol"},{"key":"10.1016\/j.eucr.2025.103251_bib18","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/00003086-200204000-00023","article-title":"Radiation therapy for low-grade soft tissue sarcoma","volume":"397","author":"Mollabashy","year":"2002","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.eucr.2025.103251_bib19","article-title":"Paratesticular leiomyosarcoma: a clinical case report","volume":"27","author":"Kolev","year":"2019","journal-title":"Urol Case Rep"},{"issue":"6","key":"10.1016\/j.eucr.2025.103251_bib20","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1111\/andr.12774","article-title":"Testosterone replacement therapy","volume":"8","author":"Barbonetti","year":"2020","journal-title":"Andrology"}],"container-title":["Urology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214442025003225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214442025003225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:57:25Z","timestamp":1778860645000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214442025003225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":20,"alternative-id":["S2214442025003225"],"URL":"https:\/\/doi.org\/10.1016\/j.eucr.2025.103251","relation":{},"ISSN":["2214-4420"],"issn-type":[{"value":"2214-4420","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bilateral testicular atrophy and hypogonadism induced by paratesticular leiomyosarcoma and untreated cryptorchidism","name":"articletitle","label":"Article Title"},{"value":"Urology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eucr.2025.103251","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"103251"}}