{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:37:10Z","timestamp":1788349030500,"version":"build-2803163510"},"reference-count":96,"publisher":"Elsevier BV","issue":"4-5","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","eu-focus.europeanurology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Urology Focus"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.euf.2017.11.004","type":"journal-article","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T19:46:53Z","timestamp":1511812013000},"page":"352-363","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":81,"title":["Erectile Dysfunction and Lower Urinary Tract Symptoms"],"prefix":"10.1016","volume":"3","author":[{"given":"Cosimo","family":"De Nunzio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus G.","family":"Roehrborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Erik","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin T.","family":"McVary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.euf.2017.11.004_bib0005","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.eururo.2004.12.013","article-title":"Sexual dysfunction and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)","volume":"47","author":"Rosen","year":"2005","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0010","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/01.mou.0000193366.53705.ce","article-title":"Update on the relationship between sexual dysfunction and lower urinary tract symptoms\/benign prostatic hyperplasia","volume":"16","author":"Rosen","year":"2006","journal-title":"Curr Opin Urol"},{"issue":"Suppl 1","key":"10.1016\/j.euf.2017.11.004_bib0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1159\/000471738","article-title":"Epidemiology of benign prostatic hyperplasia: present knowledge and studies needed","volume":"20","author":"Boyle","year":"1991","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0020","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1001\/jama.1993.03510010089036","article-title":"Impotence. NIH Consensus Development Panel on Impotence","volume":"270","author":"NIH Consensus Conference","year":"1993","journal-title":"JAMA"},{"key":"10.1016\/j.euf.2017.11.004_bib0025","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0022-5347(17)34871-1","article-title":"Impotence and its medical and physiological correlates: results of the Massachusetts male aging study","volume":"151","author":"Feldman","year":"1994","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0030","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/sj.ijir.3900622","article-title":"Epidemiology of erectile dysfunction: results of the \u201cCologne Male Survey\u201d","volume":"12","author":"Braun","year":"2000","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0035","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.eururo.2003.08.015","article-title":"Lower urinary tract symptoms and male sexual dysfunction: the Multinational Survey of the Aging Male (MSAM-7)","volume":"44","author":"Rosen","year":"2003","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0040","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.eururo.2011.06.037","article-title":"Critical analysis of the relationship between sexual dysfunctions and lower urinary tract symptoms due to benign prostatic hyperplasia","volume":"60","author":"Gacci","year":"2011","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0045","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.urology.2014.07.018","article-title":"Metabolic syndrome and lower urinary tract symptoms in patients with benign prostatic enlargement: a possible link to storage symptoms","volume":"84","author":"De Nunzio","year":"2014","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0050","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1111\/j.1742-1241.2011.02731.x","article-title":"Current benign prostatic hyperplasia treatment: impact on sexual function and management of related sexual adverse events","volume":"65","author":"Mirone","year":"2011","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.euf.2017.11.004_bib0055","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s11934-013-0373-2","article-title":"The use of PDE-5 inhibitors in the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia","volume":"14","author":"Lythgoe","year":"2013","journal-title":"Curr Urol Rep"},{"key":"10.1016\/j.euf.2017.11.004_bib0060","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.eururo.2012.02.033","article-title":"A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with \u03b1-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia","volume":"61","author":"Gacci","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0065","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1464-410X.2006.06102.x","article-title":"Lower urinary tract symptoms and sexual dysfunction: epidemiology and pathophysiology","volume":"97","author":"McVary","year":"2006","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0070","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1046\/j.1464-410X.2003.04459.x","article-title":"The association between lower urinary tract symptoms and erectile dysfunction in four centres: the UrEpik study","volume":"92","author":"Boyle","year":"2003","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0075","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1464-410X.2009.08370.x","article-title":"Lower urinary tract symptoms and sexual health: the role of gender, lifestyle and medical comorbidities","volume":"103","author":"Rosen","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0080","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.urology.2004.02.019","article-title":"Association of lower urinary tract symptoms with erectile dysfunction in Japanese men","volume":"64","author":"Terai","year":"2004","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0085","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.urology.2004.05.025","article-title":"Association between lower urinary tract symptoms and erectile dysfunction","volume":"64","author":"Ponholzer","year":"2004","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0090","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.eururo.2005.02.001","article-title":"Erectile dysfunction and lower urinary tract symptoms secondary to BPH","volume":"47","author":"McVary","year":"2005","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0095","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/ijir.2011.14","article-title":"Association of lower urinary tract symptoms and erectile dysfunction: pathophysiological aspects and implications for clinical management","volume":"23","author":"Orabi","year":"2011","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0100","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/nrurol.2014.53","article-title":"Microvascular dysfunction and efficacy of PDE5 inhibitors in BPH\u2013LUTS","volume":"11","author":"Cellek","year":"2014","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0105","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1124\/pr.111.004515","article-title":"Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction","volume":"63","author":"Andersson","year":"2011","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.euf.2017.11.004_bib0110","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1111\/j.1743-6109.2005.00080.x","article-title":"Cyclic nucleotide signaling in cavernous smooth muscle","volume":"2","author":"Lin","year":"2005","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-0045(19970915)33:1<1::AID-PROS1>3.0.CO;2-P","article-title":"Distribution of nitric oxide synthase implies a regulation of circulation, smooth muscle tone, and secretory function in the human prostate by nitric oxide","volume":"33","author":"Bloch","year":"1997","journal-title":"Prostate"},{"key":"10.1016\/j.euf.2017.11.004_bib0120","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.eururo.2015.12.048","article-title":"Latest evidence on the use of phosphodiesterase type 5 inhibitors for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia","volume":"70","author":"Gacci","year":"2016","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0125","doi-asserted-by":"crossref","first-page":"R1112","DOI":"10.1152\/ajpregu.2000.279.3.R1112","article-title":"Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I","volume":"279","author":"Persson","year":"2000","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.euf.2017.11.004_bib0130","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/nau.20475","article-title":"Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract","volume":"26","author":"Christ","year":"2007","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.euf.2017.11.004_bib0135","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/sj.ijir.3900647","article-title":"RhoA\/Rho-kinase: a novel player in the regulation of penile erection","volume":"13","author":"Chitaley","year":"2001","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0140","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1002\/j.1939-4640.2004.tb02818.x","article-title":"The link between LUTS and ED: clinical and basic science evidence","volume":"25","author":"Schiff","year":"2004","journal-title":"J Androl"},{"key":"10.1016\/j.euf.2017.11.004_bib0145","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/nrurol.2014.278","article-title":"Understanding and targeting the Rho kinase pathway in erectile dysfunction","volume":"11","author":"Sopko","year":"2014","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0150","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1097\/01.ju.0000085024.47406.6c","article-title":"Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells","volume":"170","author":"Rees","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0155","doi-asserted-by":"crossref","first-page":"F990","DOI":"10.1152\/ajprenal.00378.2002","article-title":"Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase","volume":"285","author":"Bing","year":"2003","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.euf.2017.11.004_bib0160","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","article-title":"Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report","volume":"106","author":"Cholesterol","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.euf.2017.11.004_bib0165","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.trsl.2017.01.001","article-title":"Cardiovascular consequences of metabolic syndrome","volume":"183","author":"Tune","year":"2017","journal-title":"Transl Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0170","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.eururo.2011.11.013","article-title":"The correlation between metabolic syndrome and prostatic diseases","volume":"61","author":"De Nunzio","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0175","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1097\/01.ju.0000173072.73702.64","article-title":"Autonomic nervous system overactivity in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia","volume":"174","author":"McVary","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0180","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1080\/00365590802468750","article-title":"Substantial detrusor overactivity in conscious spontaneously hypertensive rats with hyperactive behaviour","volume":"43","author":"Jin","year":"2009","journal-title":"Scand J Urol Nephrol"},{"key":"10.1016\/j.euf.2017.11.004_bib0185","doi-asserted-by":"crossref","first-page":"R682","DOI":"10.1152\/ajpregu.00349.2002","article-title":"Erectile dysfunction in spontaneously hypertensive rats: pathophysiological mechanisms","volume":"284","author":"Behr-Roussel","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.euf.2017.11.004_bib0190","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/S0022-5347(05)68995-1","article-title":"Atherosclerosis-induced chronic ischemia causes bladder fibrosis and non-compliance in the rabbit","volume":"161","author":"Azadzoi","year":"1999","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0195","doi-asserted-by":"crossref","first-page":"F738","DOI":"10.1152\/ajprenal.00333.2015","article-title":"LUTS in pelvic ischemia: a new concept in voiding dysfunction","volume":"310","author":"Thurmond","year":"2016","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.euf.2017.11.004_bib0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/luts.12084","article-title":"Chronic pelvic ischemia: contribution to the pathogenesis of lower urinary tract symptoms (LUTS): a new target for pharmacological treatment?","volume":"7","author":"Andersson","year":"2015","journal-title":"Low Urin Tract Symptoms"},{"key":"10.1016\/j.euf.2017.11.004_bib0205","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1016\/j.juro.2011.06.047","article-title":"Molecular reactions and ultrastructural damage in the chronically ischemic bladder","volume":"186","author":"Azadzoi","year":"2011","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0210","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/bju.12728","article-title":"Metabolic syndrome and benign prostatic enlargement: a systematic review and meta-analysis","volume":"115","author":"Gacci","year":"2015","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0215","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1111\/jsm.12885","article-title":"The relationship between metabolic syndrome, its components, and erectile dysfunction: a systematic review and a meta-analysis of observational studies","volume":"12","author":"Besiroglu","year":"2015","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0220","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0090-4295(00)00938-9","article-title":"Similarities of prostate and breast cancer: evolution, diet, and estrogens","volume":"57","author":"Coffey","year":"2001","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0225","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3109\/13685538.2015.1083972","article-title":"Hormonal determinants of erectile dysfunction and lower urinary tract symptoms in middle-aged and elderly men with prediabetes","volume":"18","author":"Rabijewski","year":"2015","journal-title":"Aging Male"},{"key":"10.1016\/j.euf.2017.11.004_bib0230","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1111\/j.1464-410X.2012.11085.x","article-title":"A new experimental rat model of erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: the testosterone-supplemented spontaneously hypertensive rat","volume":"110","author":"Oudot","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0235","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.1111\/j.1743-6109.2010.01762.x","article-title":"Emerging role for TNF-\u03b1 in erectile dysfunction","volume":"7","author":"Carneiro","year":"2010","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0240","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1002\/pros.21027","article-title":"Inflammation in benign prostatic hyperplasia: a 282 patients\u2019 immunohistochemical analysis","volume":"69","author":"Robert","year":"2009","journal-title":"Prostate"},{"key":"10.1016\/j.euf.2017.11.004_bib0245","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/nrurol.2016.168","article-title":"Inflammatory mediators in the development and progression of benign prostatic hyperplasia","volume":"13","author":"De Nunzio","year":"2016","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0250","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1111\/j.1464-410X.2009.08503.x","article-title":"Ejaculatory dysfunction in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia","volume":"104","author":"Rosen","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0255","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.urology.2004.01.039","article-title":"Obstructive lower urinary tract symptoms correlate with erectile dysfunction","volume":"63","author":"Elliott","year":"2004","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0260","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1111\/jsm.12261","article-title":"BPH\/LUTS and ED: common pharmacological pathways for a common treatment","volume":"10","author":"Fusco","year":"2013","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0265","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/ijcp.12044","article-title":"Coexisting lower urinary tract symptoms and erectile dysfunction: a systematic review of epidemiological data","volume":"67","author":"Seftel","year":"2013","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.euf.2017.11.004_bib0270","first-page":"119","article-title":"New treatment strategies for benign prostatic hyperplasia in the frail elderly population: a systematic review","volume":"69","author":"Albisinni","year":"2017","journal-title":"Minerva Urol Nefrol"},{"key":"10.1016\/j.euf.2017.11.004_bib0275","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1097\/01.ju.0000078083.38675.79","article-title":"AUA guideline on management of benign prostatichyperplasia (2003). Chapter 1: diagnosis and treatment recommendations","volume":"170","author":"AUA Practice Guidelines Committee","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0280","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1464-410X.2008.07494.x","article-title":"Lower urinary tract symptoms and sexual dysfunction: a common approach","volume":"101","author":"Giuliano","year":"2008","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0285","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s002400050015","article-title":"Sexual functions in patients with benign prostatic hyperplasia before and after transurethral resection of the prostate","volume":"26","author":"Kunelius","year":"1998","journal-title":"Urol Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0290","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1046\/j.1532-5415.2001.49088.x","article-title":"Correlates for erectile and ejaculatory dysfunction in older Dutch men: a community-based study","volume":"49","author":"Blanker","year":"2001","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.euf.2017.11.004_bib0295","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1046\/j.1464-4096.2001.01817.x","article-title":"Sexual function before and after various treatments for symptomatic benign prostatic hyperplasia","volume":"89","author":"Leliefeld","year":"2002","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0300","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1038\/sj.ijir.3900892","article-title":"Prevalence and correlates of erectile dysfunction in Salvador, northeastern Brazil: a population-based study","volume":"14","author":"Moreira","year":"2002","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0305","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1097\/01.ju.0000067940.76090.73","article-title":"Alf-One Study Group Sexual dysfunction in 1,274 European men suffering from lower urinary tract symptoms","volume":"169","author":"Vallancien","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0310","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S0025-6196(11)62626-8","article-title":"Lower urinary tract symptoms and sexual dysfunction in community-dwelling men","volume":"79","author":"Chung","year":"2004","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.euf.2017.11.004_bib0315","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.eururo.2004.04.005","article-title":"Lower urinary tract symptoms (LUTS) and sexual function in both sexes","volume":"46","author":"Hansen","year":"2004","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0320","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s11934-004-0046-2","article-title":"The medical therapy of prostatic symptoms trial","volume":"5","author":"McVary","year":"2004","journal-title":"Curr Urol Rep"},{"key":"10.1016\/j.euf.2017.11.004_bib0325","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.eururo.2004.06.017","article-title":"What is the relationship between male sexual function and lower urinary tract symptoms (LUTS)?","volume":"46","author":"Sak","year":"2004","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0330","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1743-6109.2005.20363.x","article-title":"Association between the bothersomeness of lower urinary tract symptoms and the prevalence of erectile dysfunction","volume":"2","author":"Shiri","year":"2005","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0335","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.eururo.2005.04.032","article-title":"Lower urinary tract symptoms in patients with erectile dysfunction: is there a vascular association?","volume":"48","author":"El-Sakka","year":"2005","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0340","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1111\/j.1464-410X.2005.05831.x","article-title":"Lower urinary tract symptoms and male sexual dysfunction in Asia: a survey of ageing men from five Asian countries","volume":"96","author":"Li","year":"2005","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0345","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1097\/01.ju.0000152088.00361.a7","article-title":"The relationship among lower urinary tract symptoms, prostate specific antigen and erectile dysfunction in men with benign prostatic hyperplasia: results from the PROSCAR long-term efficacy and safety study","volume":"173","author":"Paick","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0350","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000094818","article-title":"Are lower urinary tract symptoms associated with erectile dysfunction in aging males of Taiwan?","volume":"77","author":"Liu","year":"2006","journal-title":"Urol Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0355","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/sj.ijir.3901557","article-title":"Correlation between lower urinary tract symptoms and erectile dysfunction in men presenting for prostate cancer screening","volume":"19","author":"Reggio","year":"2007","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.euf.2017.11.004_bib0360","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.juro.2007.08.167","article-title":"Relationship between lower urinary tract symptoms and erectile dysfunction: results from the Boston Area Community Health Survey","volume":"179","author":"Brookes","year":"2008","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0365","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1111\/j.1743-6109.2008.00877.x","article-title":"Evaluation of the association between lower urinary tract symptoms and erectile dysfunction, considering its multiple risk factors","volume":"5","author":"Rhoden","year":"2008","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0370","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1159\/000127345","article-title":"Association between erectile dysfunction and lower urinary tract symptoms due to benign prostatic hyperplasia in Nigerian men","volume":"80","author":"Ikuerowo","year":"2008","journal-title":"Urol Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0375","first-page":"260","article-title":"Sexual dysfunction in aging men with lower urinary tract symptoms","volume":"5","author":"Mehraban","year":"2008","journal-title":"Urol J"},{"key":"10.1016\/j.euf.2017.11.004_bib0380","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s11255-008-9386-z","article-title":"The relationship between lower urinary tract symptoms (LUTS), diagnostic indicators of benign prostatic hyperplasia (BPH), and erectile dysfunction in patients with moderate to severely symptomatic BPH","volume":"40","author":"Ozayar","year":"2008","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.euf.2017.11.004_bib0385","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1464-410X.2007.07320.x","article-title":"An Asian multinational prospective observational registry of patients with benign prostatic hyperplasia, with a focus on comorbidities, lower urinary tract symptoms and sexual function","volume":"101","author":"Li","year":"2008","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2017.11.004_bib0390","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1111\/j.1743-6109.2008.00988.x","article-title":"Erectile dysfunction and comorbidities in aging men: an urban cross-sectional study in Malaysia","volume":"5","author":"Khoo","year":"2008","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0395","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1016\/j.juro.2008.01.150","article-title":"A prospective study of lower urinary tract symptoms and erectile dysfunction","volume":"179","author":"Mondul","year":"2008","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0400","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.urology.2008.05.034","article-title":"Association of sexual dysfunction with lower urinary tract symptoms of BPH and BPH medical therapies: results from the BPH Registry","volume":"73","author":"Rosen","year":"2009","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0405","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/13685530902777425","article-title":"Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome","volume":"12","author":"Demir","year":"2009","journal-title":"Aging Male"},{"key":"10.1016\/j.euf.2017.11.004_bib0410","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1111\/j.1743-6109.2009.01324.x","article-title":"Correlation between lower urinary tract symptoms (LUTS) and sexual function in benign prostatic hyperplasia: impact of treatment of LUTS on sexual function","volume":"6","author":"Jung","year":"2009","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0415","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1111\/j.1743-6109.2009.01295.x","article-title":"A prospective study on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction: results from a large study in elderly Chinese in southern China","volume":"6","author":"Wong","year":"2009","journal-title":"J Sex Med"},{"key":"10.1016\/j.euf.2017.11.004_bib0420","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3109\/13685531003586975","article-title":"The impact of irritative lower urinary tract symptoms on erectile dysfunction in aging Taiwanese males","volume":"13","author":"Tsai","year":"2010","journal-title":"Aging Male"},{"key":"10.1016\/j.euf.2017.11.004_bib0425","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s11255-010-9888-3","article-title":"The correlation between international prostate symptoms score and sexual health inventory in men with lower urinary tract symptoms","volume":"43","author":"Nasir","year":"2011","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.euf.2017.11.004_bib0430","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.urology.2013.07.003","article-title":"Association of lower urinary tract symptom\/benign prostatic hyperplasia measures with International Index of Erectile Function 5 in middle-aged policemen of Korea and the role of metabolic syndrome and testosterone in their relationship","volume":"82","author":"Lee","year":"2013","journal-title":"Urology"},{"key":"10.1016\/j.euf.2017.11.004_bib0435","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3109\/13685538.2010.529197","article-title":"Impact of metabolic syndrome on erectile dysfunction and lower urinary tract symptoms in benign prostatic hyperplasia patients","volume":"14","author":"Aktas","year":"2011","journal-title":"Aging Male"},{"key":"10.1016\/j.euf.2017.11.004_bib0440","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3109\/13685538.2011.646342","article-title":"Association between lower urinary tract symptoms and sexual dysfunction assessed using the core lower urinary tract symptom score and International Index of Erectile Function-5 questionnaires","volume":"15","author":"Nakamura","year":"2012","journal-title":"Aging Male"},{"key":"10.1016\/j.euf.2017.11.004_bib0445","doi-asserted-by":"crossref","first-page":"135","DOI":"10.5173\/ceju.2012.03.art7","article-title":"Assessing the influence of benign prostatic hyperplasia (BPH) on erectile dysfunction (ED) among patients in Poland","volume":"65","author":"Dutkiewicz","year":"2012","journal-title":"Cent Eur J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0450","doi-asserted-by":"crossref","first-page":"180","DOI":"10.5213\/inj.2013.17.4.180","article-title":"Lower urinary tract symptoms and erectile dysfunction in men with type 2 diabetes mellitus","volume":"17","author":"Song","year":"2013","journal-title":"Int Neurourol J"},{"key":"10.1016\/j.euf.2017.11.004_bib0455","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1016\/j.juro.2013.05.048","article-title":"Interactions between lower urinary tract symptoms and cardiovascular risk factors determine distinct patterns of erectile dysfunction: a latent class analysis","volume":"190","author":"Barbosa","year":"2013","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0460","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.juro.2014.08.086","article-title":"Cross-sectional and longitudinal associations of sexual function with lower urinary tract symptoms in men with benign prostatic hyperplasia","volume":"193","author":"Fwu","year":"2015","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0465","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/luts.12033","article-title":"Lower urinary tract symptoms are associated with erectile function and psychological symptoms in men with late-onset hypogonadism syndrome","volume":"6","author":"Shigehara","year":"2014","journal-title":"LUTS Low Urin Tract Symptoms"},{"key":"10.1016\/j.euf.2017.11.004_bib0470","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.12659\/MSM.891180","article-title":"Lower urinary tract symptoms, erectile dysfunction, and their correlation in men aged 50 years and above: a cross-sectional survey in Beijing, China","volume":"20","author":"Song","year":"2014","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.euf.2017.11.004_bib0475","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s00345-015-1703-4","article-title":"The correlation between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED): results from a survey in males from Mexico City (MexiLUTS)","volume":"34","author":"Gonzalez-Sanchez","year":"2016","journal-title":"World J Urol"},{"key":"10.1016\/j.euf.2017.11.004_bib0480","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/ijir.2016.8","article-title":"Prevalence and risk factors for erectile dysfunction and lower urinary tract symptoms in Russian Federation men: analysis from a national population-based multicenter study","volume":"28","author":"Korneyev","year":"2016","journal-title":"Int J Impot Res"}],"container-title":["European Urology Focus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405456917302602?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405456917302602?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T06:47:19Z","timestamp":1762498039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405456917302602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":96,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S2405456917302602"],"URL":"https:\/\/doi.org\/10.1016\/j.euf.2017.11.004","relation":{},"ISSN":["2405-4569"],"issn-type":[{"value":"2405-4569","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Erectile Dysfunction and Lower Urinary Tract Symptoms","name":"articletitle","label":"Article Title"},{"value":"European Urology Focus","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.euf.2017.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}