{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T23:23:46Z","timestamp":1768001026767,"version":"3.49.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","eu-focus.europeanurology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Urology Focus"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.euf.2018.06.016","type":"journal-article","created":{"date-parts":[[2018,7,6]],"date-time":"2018-07-06T10:22:08Z","timestamp":1530872528000},"page":"95-101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of Augmented Antimicrobial Prophylaxis and Rectal Swab Culture\u2013guided Targeted Prophylaxis on the Risk of Sepsis Following Transrectal Prostate Biopsy"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2884-7126","authenticated-orcid":false,"given":"Marios","family":"Hadjipavlou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazin","family":"Eragat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Kenny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Pantelidou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waseem","family":"Mulhem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martino","family":"Dall\u2019Antonia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Y.","family":"Hammadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.euf.2018.06.016_bib0005","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.eururo.2013.05.049","article-title":"Systematic review of complications of prostate biopsy","volume":"64","author":"Loeb","year":"2013","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0010","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.eururo.2011.12.058","article-title":"Infectious complications and hospital admissions after prostate biopsy in a European randomized trial","volume":"61","author":"Loeb","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0015","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1016\/j.juro.2011.06.057","article-title":"Complications after prostate biopsy: data from SEER-Medicare","volume":"186","author":"Loeb","year":"2011","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0020","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.eururo.2012.06.003","article-title":"Infective complications after prostate biopsy: outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, a prospective multinational multicentre prostate biopsy study","volume":"63","author":"Wagenlehner","year":"2013","journal-title":"Eur Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0025","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1093\/jac\/dkq471","article-title":"Significant ecological impact on the progression of fluoroquinolone resistance in Escherichia coli with increased community use of moxifloxacin, levofloxacin and amoxicillin\/clavulanic acid","volume":"66","author":"Cuevas","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.euf.2018.06.016_bib0030","unstructured":"European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2015. https:\/\/ecdc.europa.eu\/sites\/portal\/files\/media\/en\/publications\/Publications\/antimicrobial-resistance-europe-2015.pdf."},{"key":"10.1016\/j.euf.2018.06.016_bib0035","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/nrurol.2013.322","article-title":"Reducing infection rates after prostate biopsy","volume":"11","author":"Wagenlehner","year":"2014","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0040","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/nrurol.2016.176","article-title":"Planning for the post-antibiotic era\u2014why we must avoid TRUS-guided biopsy sampling","volume":"13","author":"Murphy","year":"2016","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0045","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.urology.2011.09.057","article-title":"Rectal cultures before transrectal ultrasound-guided prostate biopsy reduce post-prostatic biopsy infection rates","volume":"79","author":"Duplessis","year":"2012","journal-title":"Urology"},{"key":"10.1016\/j.euf.2018.06.016_bib0050","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1111\/j.1464-410X.2012.11637.x","article-title":"Ciprofloxacin resistance in the faecal carriage of patients undergoing transrectal ultrasound guided prostate biopsy","volume":"111","author":"Taylor","year":"2013","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0055","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1159\/000448595","article-title":"Impact of rectal swabs on infectious complications after transrectal prostate biopsy","volume":"97","author":"Trujillo","year":"2016","journal-title":"Urol Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0060","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/j.juro.2014.06.005","article-title":"Fluoroquinolone resistant rectal colonization predicts risk of infectious complications after transrectal prostate biopsy","volume":"192","author":"Liss","year":"2014","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0065","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1093\/jac\/dks391","article-title":"BSAC Working Party on Susceptibility Testing: BSAC standardized disc susceptibility testing method (version 11)","volume":"67","author":"Howe","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.euf.2018.06.016_bib0070","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/CCM.0b013e31827e83af","article-title":"Surviving sepsis campaign","volume":"41","author":"Dellinger","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.euf.2018.06.016_bib0075","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.1093\/cid\/cit704","article-title":"Is fosfomycin a potential treatment alternative for multidrug-resistant gram-negative prostatitis?","volume":"58","author":"Gardiner","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.euf.2018.06.016_bib0080","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00345-016-1867-6","article-title":"Antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: fosfomycin trometamol, an attractive alternative","volume":"35","author":"Cai","year":"2017","journal-title":"World J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0085","doi-asserted-by":"crossref","first-page":"e286","DOI":"10.1016\/j.juro.2015.02.1206","article-title":"Fosfomycin for antibiotic prophylaxis prior to transrectal ultrasound-guided prostate biopsy","volume":"193","author":"Colhoun","year":"2015","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0090","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.juro.2017.08.040","article-title":"Predictors of infectious complications after targeted prophylaxis for prostate needle biopsy","volume":"199","author":"Papagiannopoulos","year":"2018","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0095","doi-asserted-by":"crossref","DOI":"10.1007\/s00345-018-2319-2","article-title":"Chemoprophylaxis during transrectal prostate needle biopsy: critical analysis through randomized clinical trial","author":"Elshal","year":"2018","journal-title":"World J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0100","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.juro.2015.03.126","article-title":"A statewide intervention to reduce hospitalizations after prostate biopsy","volume":"194","author":"Womble","year":"2015","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0105","first-page":"2216","article-title":"A prospective randomized trial of 1-day versus 3-day antibiotic prophylaxis for transrectal ultrasound guided prostate biopsy","volume":"11","author":"Sabbagh","year":"2004","journal-title":"Can J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0110","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1464-410X.2008.08128.x","article-title":"One preoperative dose randomized against 3-day antibiotic prophylaxis for transrectal ultrasonography-guided prostate biopsy","volume":"103","author":"Briffaux","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0115","article-title":"Antibiotic prophylaxis for transrectal prostate biopsy","volume":"5","author":"Zani","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.euf.2018.06.016_bib0120","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/2047-2994-1-39","article-title":"The gut is the epicentre of antibiotic resistance","volume":"1","author":"Carlet","year":"2012","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.euf.2018.06.016_bib0125","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1111\/j.1464-410X.2011.10561.x","article-title":"Infection after transrectal ultrasonography-guided prostate biopsy: increased relative risks after recent international travel or antibiotic use","volume":"109","author":"Patel","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0130","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.juro.2017.01.103","article-title":"An update of the American Urological Association white paper on the prevention and treatment of the more common complications related to prostate biopsy","volume":"198","author":"Liss","year":"2017","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0135","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.urology.2014.10.047","article-title":"Reduction in hospital admissions with the addition of prophylactic intramuscular ceftriaxone before transrectal ultrasonography\u2013guided prostate biopsies","volume":"85","author":"Luong","year":"2015","journal-title":"Urology"},{"key":"10.1016\/j.euf.2018.06.016_bib0140","series-title":"AUA best practice policy statement on urologic surgery antimicrobial prophylaxis","author":"Wolf","year":"2012"},{"key":"10.1016\/j.euf.2018.06.016_bib0145","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1080\/17843286.1989.11718041","article-title":"Penetration of temocillin into prostatic tissue after intravenous dosing","volume":"44","author":"Baert","year":"1989","journal-title":"Acta Clin Belg"},{"key":"10.1016\/j.euf.2018.06.016_bib0150","first-page":"2418","article-title":"Comment on: The national burden of infections after prostate biopsy in England and Wales: a wake-up call for better prevention","volume":"68","author":"Balakrishnan","year":"2013","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.euf.2018.06.016_bib0155","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/bju.12590","article-title":"Ertapenem prophylaxis reduces sepsis after transrectal biopsy of the prostate","volume":"113","author":"Losco","year":"2014","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0160","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.juro.2017.03.077","article-title":"Routine ertapenem prophylaxis for transrectal ultrasound guided prostate biopsy does not select for carbapenem resistant organisms: a prospective cohort study","volume":"198","author":"Bloomfield","year":"2017","journal-title":"J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0165","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/bju.13402","article-title":"The role of targeted prophylactic antimicrobial therapy before transrectal ultrasonography-guided prostate biopsy in reducing infection rates: a systematic review","volume":"117","author":"Cussans","year":"2016","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0170","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1089\/mdr.2016.0040","article-title":"Fluoroquinolone-resistant sequence type 131 subgroups O25b and O16 among extraintestinal Escherichia coli isolates from community-acquired urinary tract infections","volume":"23","author":"Hefzy","year":"2017","journal-title":"Microb Drug Resist"},{"key":"10.1016\/j.euf.2018.06.016_bib0175","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.urology.2012.10.056","article-title":"Prevalence of ST131 among fluoroquinolone-resistant Escherichia coli obtained from rectal swabs before transrectal prostate biopsy","volume":"81","author":"Liss","year":"2013","journal-title":"Urology"},{"key":"10.1016\/j.euf.2018.06.016_bib0180","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0140-6736(16)32401-1","article-title":"Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study","volume":"389","author":"Ahmed","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.euf.2018.06.016_bib0185","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/pcan.2017.13","article-title":"Magnetic resonance imaging targeted transperineal prostate biopsy: a local anaesthetic approach","volume":"20","author":"Bass","year":"2017","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.1016\/j.euf.2018.06.016_bib0190","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.urology.2013.02.019","article-title":"Morbidity after transperineal prostate biopsy in 3000 patients undergoing 12 vs 18 vs more than 24 needle cores","volume":"81","author":"Pepe","year":"2013","journal-title":"Urology"},{"key":"10.1016\/j.euf.2018.06.016_bib0195","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/bju.12282","article-title":"Indications, results and safety profile of transperineal sector biopsies (TPSB) of the prostate: a single centre experience of 634 cases","volume":"114","author":"Vyas","year":"2014","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0200","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1464-410X.2012.11657.x","article-title":"Outcomes of transperineal template-guided prostate biopsy in 409 patients","volume":"112","author":"Symons","year":"2013","journal-title":"BJU Int"},{"key":"10.1016\/j.euf.2018.06.016_bib0205","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/s00345-016-1985-1","article-title":"Zero hospital admissions for infection after 577 transperineal prostate biopsies using single-dose cephazolin prophylaxis","volume":"35","author":"Pepdjonovic","year":"2017","journal-title":"World J Urol"},{"key":"10.1016\/j.euf.2018.06.016_bib0210","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"}],"container-title":["European Urology Focus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405456918301640?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405456918301640?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T06:50:22Z","timestamp":1762498222000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405456918301640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S2405456918301640"],"URL":"https:\/\/doi.org\/10.1016\/j.euf.2018.06.016","relation":{},"ISSN":["2405-4569"],"issn-type":[{"value":"2405-4569","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Augmented Antimicrobial Prophylaxis and Rectal Swab Culture\u2013guided Targeted Prophylaxis on the Risk of Sepsis Following Transrectal Prostate Biopsy","name":"articletitle","label":"Article Title"},{"value":"European Urology Focus","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.euf.2018.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}