{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:41:25Z","timestamp":1792453285457,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"am","delay-in-days":411,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA269553"],"award-info":[{"award-number":["R01 CA269553"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003252","name":"Lunds Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003252","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R03 AG083596"],"award-info":[{"award-number":["R03 AG083596"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["euoncology.europeanurology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Urology Oncology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.euo.2025.04.001","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T06:24:47Z","timestamp":1745562287000},"page":"857-865","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Associations Between Prostate Cancer and Dementia: A Nationwide Study in Sweden"],"prefix":"10.1016","volume":"8","author":[{"given":"Casey","family":"Crump","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e4r","family":"Stattin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Sundquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingkai","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiva","family":"Sieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Sundquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.euo.2025.04.001_b0005","first-page":"409","article-title":"Cancer treatment and survivorship statistics, 2022","volume":"72","author":"Miller","year":"2022","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.euo.2025.04.001_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jalz.2012.11.007","article-title":"The global prevalence of dementia: a systematic review and metaanalysis","volume":"9","author":"Prince","year":"2013","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.euo.2025.04.001_b0015","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S1383-5742(02)00046-7","article-title":"Genetic and environmental factors in cancer and neurodegenerative diseases","volume":"512","author":"Migliore","year":"2002","journal-title":"Mutat Res"},{"key":"10.1016\/j.euo.2025.04.001_b0020","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.yhbeh.2012.04.006","article-title":"Gender, sex steroid hormones, and Alzheimer's disease","volume":"63","author":"Vest","year":"2013","journal-title":"Horm Behav"},{"key":"10.1016\/j.euo.2025.04.001_b0025","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1001\/jama.285.17.2195-a","article-title":"Chemical andropause and amyloid-beta peptide","volume":"285","author":"Gandy","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.euo.2025.04.001_b0030","doi-asserted-by":"crossref","first-page":"e1442","DOI":"10.1136\/bmj.e1442","article-title":"Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study","volume":"344","author":"Driver","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.euo.2025.04.001_b0035","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1007\/s10072-015-2282-2","article-title":"Inverse relationship between cancer and Alzheimer's disease: a systemic review meta-analysis","volume":"36","author":"Zhang","year":"2015","journal-title":"Neurol Sci"},{"key":"10.1016\/j.euo.2025.04.001_b0040","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1212\/WNL.0b013e31829c5ec1","article-title":"Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study","volume":"81","author":"Musicco","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.euo.2025.04.001_b0045","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.25515","article-title":"Association between Alzheimer disease and cancer with evaluation of study biases: a systematic review and meta-analysis","volume":"3","author":"Ospina-Romero","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.euo.2025.04.001_b0050","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/j.jalz.2017.04.012","article-title":"Association of cancer and Alzheimer's disease risk in a national cohort of veterans","volume":"13","author":"Frain","year":"2017","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.euo.2025.04.001_b0055","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.3233\/JAD-170847","article-title":"Putative gonadotropin-releasing hormone agonist therapy and dementia: an application of Medicare hospitalization claims data","volume":"63","author":"Smith","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.euo.2025.04.001_b0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179857","article-title":"Risk of Alzheimer's disease or dementia following a cancer diagnosis","volume":"12","author":"Bowles","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.euo.2025.04.001_b0065","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/andr.12187","article-title":"Androgen deprivation therapy did not increase the risk of Alzheimer's and Parkinson's disease in patients with prostate cancer","volume":"4","author":"Chung","year":"2016","journal-title":"Andrology"},{"key":"10.1016\/j.euo.2025.04.001_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.currproblcancer.2020.100578","article-title":"Risk of dementia in prostate cancer survivors: a nationwide cohort study in Korea","volume":"44","author":"Kang","year":"2020","journal-title":"Curr Probl Cancer"},{"key":"10.1016\/j.euo.2025.04.001_b0075","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00432-014-1773-5","article-title":"Alzheimer disease and cancer risk: a meta-analysis","volume":"141","author":"Shi","year":"2015","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1016\/j.euo.2025.04.001_b0080","doi-asserted-by":"crossref","first-page":"7616","DOI":"10.18632\/oncotarget.24139","article-title":"Alzheimer's disease is associated with prostate cancer: a population-based study","volume":"9","author":"Lin","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.euo.2025.04.001_b0085","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.eururo.2023.04.026","article-title":"Long-term risks of depression and suicide among men with prostate cancer: a national cohort study","volume":"84","author":"Crump","year":"2023","journal-title":"Eur Urol"},{"key":"10.1016\/j.euo.2025.04.001_b0090","doi-asserted-by":"crossref","DOI":"10.1093\/jncics\/pkad046","article-title":"Risks of alcohol and drug use disorders in prostate cancer survivors: a national cohort study","volume":"7","author":"Crump","year":"2023","journal-title":"JNCI Cancer Spectr"},{"key":"10.1016\/j.euo.2025.04.001_b0095","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.euo.2024.03.012","article-title":"Mortality risks associated with depression in men with prostate cancer","volume":"7","author":"Crump","year":"2024","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.euo.2025.04.001_b0100","doi-asserted-by":"crossref","first-page":"210","DOI":"10.2340\/sju.v59.42656","article-title":"2023\/2024 update of the national prostate cancer guidelines in Sweden","volume":"59","author":"Stranne","year":"2024","journal-title":"Scand J Urol"},{"key":"10.1016\/j.euo.2025.04.001_b0105","doi-asserted-by":"crossref","first-page":"190","DOI":"10.2340\/sju.v59.42272","article-title":"How to improve cancer care by use of guidelines and quality registers","volume":"59","author":"Stattin","year":"2024","journal-title":"Scand J Urol"},{"key":"10.1016\/j.euo.2025.04.001_b0110","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1093\/ije\/dys068","article-title":"Cohort profile: the National Prostate Cancer Register of Sweden and Prostate Cancer data Base Sweden 2.0","volume":"42","author":"Van Hemelrijck","year":"2013","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.euo.2025.04.001_b0115","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ejca.2014.10.025","article-title":"Evaluation of data quality in the National Prostate Cancer Register of Sweden","volume":"51","author":"Tomic","year":"2015","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.euo.2025.04.001_b0120","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3233\/JAD-170572","article-title":"Detection of dementia cases in two Swedish Health registers: a validation study","volume":"61","author":"Rizzuto","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.euo.2025.04.001_b0125","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1200\/JCO.2015.63.6266","article-title":"Androgen deprivation therapy and future Alzheimer's disease risk","volume":"34","author":"Nead","year":"2016","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.euo.2025.04.001_b0130","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1001\/jamaoncol.2016.3662","article-title":"Association between androgen deprivation therapy and risk of dementia","volume":"3","author":"Nead","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.euo.2025.04.001_b0135","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3233\/JAD-220436","article-title":"Risk of dementia in cancer survivors: a meta-analysis of population-based cohort studies","volume":"89","author":"Zhang","year":"2022","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.euo.2025.04.001_b0140","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/bju.14666","article-title":"Androgen deprivation therapy for prostate cancer and risk of dementia","volume":"124","author":"Robinson","year":"2019","journal-title":"BJU Int"},{"key":"10.1016\/j.euo.2025.04.001_b0145","doi-asserted-by":"crossref","first-page":"593","DOI":"10.4143\/crt.2018.119","article-title":"Correlation of androgen deprivation therapy with cognitive dysfunction in patients with prostate cancer: a nationwide population-based study using the National Health Insurance Service Database","volume":"51","author":"Tae","year":"2019","journal-title":"Cancer Res Treat"},{"key":"10.1016\/j.euo.2025.04.001_b0150","doi-asserted-by":"crossref","first-page":"193","DOI":"10.14283\/jpad.2023.8","article-title":"A large retrospective cohort study on the risk of Alzheimer's disease and related dementias in association with vascular diseases and cancer therapy in men with prostate cancer","volume":"10","author":"Du","year":"2023","journal-title":"J Prev Alzheimers Dis"},{"key":"10.1016\/j.euo.2025.04.001_b0155","doi-asserted-by":"crossref","first-page":"437","DOI":"10.21873\/anticanres.16179","article-title":"Androgen deprivation therapy unrelated to Alzheimer's disease in the UK Biobank cohort","volume":"43","author":"Lehrer","year":"2023","journal-title":"Anticancer Res"},{"key":"10.1016\/j.euo.2025.04.001_b0160","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/s41391-023-00785-w","article-title":"Androgen deprivation therapy for prostate cancer and neurocognitive disorders: a systematic review and meta-analysis","volume":"27","author":"Hinojosa-Gonzalez","year":"2024","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.1016\/j.euo.2025.04.001_b0165","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/s41391-022-00541-6","article-title":"Neurocognitive impairment associated with traditional and novel androgen receptor signaling inhibitors +\/- androgen deprivation therapy: a pharmacovigilance study","volume":"26","author":"Briggs","year":"2023","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.1016\/j.euo.2025.04.001_b0170","article-title":"Androgen deprivation therapy exacerbates Alzheimer's-associated cognitive decline via increased brain immune cell infiltration","volume":"10","author":"Zhang","year":"2024","journal-title":"Sci Adv"},{"key":"10.1016\/j.euo.2025.04.001_b0175","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/iju.13409","article-title":"Association between androgen deprivation therapy and anxiety among 78 000 patients with localized prostate cancer","volume":"24","author":"Dinh","year":"2017","journal-title":"Int J Urol"},{"key":"10.1016\/j.euo.2025.04.001_b0180","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1001\/archinte.168.18.2033","article-title":"Effect of a dementia diagnosis on survival of older patients after a diagnosis of breast, colon, or prostate cancer: implications for cancer care","volume":"168","author":"Raji","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.euo.2025.04.001_b0185","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/gps.2191","article-title":"Clinical and cost effectiveness of services for early diagnosis and intervention in dementia","volume":"24","author":"Banerjee","year":"2009","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.euo.2025.04.001_b0190","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/agm2.12069","article-title":"Advances in screening instruments for Alzheimer's disease","volume":"2","author":"Zhou","year":"2019","journal-title":"Aging Med (Milton)"},{"key":"10.1016\/j.euo.2025.04.001_b0195","unstructured":"Ferlay J, Ervik M, Lam F, et al. Global Cancer Observatory: cancer today. International Agency for Research on Cancer. https:\/\/gco.iarc.who.int\/today."},{"key":"10.1016\/j.euo.2025.04.001_b0200","doi-asserted-by":"crossref","first-page":"e519","DOI":"10.1212\/WNL.0000000000010022","article-title":"Twenty-seven-year time trends in dementia incidence in Europe and the United States: the Alzheimer Cohorts Consortium","volume":"95","author":"Wolters","year":"2020","journal-title":"Neurology"}],"container-title":["European Urology Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2588931125000914?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2588931125000914?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T19:26:04Z","timestamp":1762629964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2588931125000914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S2588931125000914"],"URL":"https:\/\/doi.org\/10.1016\/j.euo.2025.04.001","relation":{},"ISSN":["2588-9311"],"issn-type":[{"value":"2588-9311","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations Between Prostate Cancer and Dementia: A Nationwide Study in Sweden","name":"articletitle","label":"Article Title"},{"value":"European Urology Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.euo.2025.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 European Association of Urology. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}