{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:30:53Z","timestamp":1790836253131,"version":"4.1.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A case of an electrical storm occurring in a patient implanted with a cardioverter-defibrillator for Brugada syndrome is reported. Recurrent ventricular fibrillation was initiated by short-coupled isolated monomorphic ventricular premature beats probably originating from the right ventricular outflow tract, associated with a manifest electrocardiographic pattern of Brugada syndrome. Infusion of atropine accelerated the heart rate but did not prevent ventricular fibrillation, however, low doses of isoprenaline quickly obviated any recurrence of ventricular fibrillation. This was associated with the disappearance of the short-coupled premature beats together with a normalization of the electrocardiographic pattern. Possible mechanisms are discussed according to the accepted pathophysiological hypothesis.<\/jats:p>","DOI":"10.1016\/j.eupc.2003.11.009","type":"journal-article","created":{"date-parts":[[2004,3,3]],"date-time":"2004-03-03T05:17:38Z","timestamp":1078291058000},"page":"130-133","source":"Crossref","is-referenced-by-count":93,"title":["Electrical storm in Brugada syndrome successfully treated using isoprenaline"],"prefix":"10.1093","volume":"6","author":[{"given":"P.","family":"Maury","sequence":"first","affiliation":[{"name":"Federation of Cardiology, University Hospital Rangueil a \u00a0 \u00a0 31059 Toulouse Cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Couderc","sequence":"additional","affiliation":[{"name":"Federation of Cardiology, University Hospital Rangueil a \u00a0 \u00a0 31059 Toulouse Cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Delay","sequence":"additional","affiliation":[{"name":"Federation of Cardiology, University Hospital Rangueil a \u00a0 \u00a0 31059 Toulouse Cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Boveda","sequence":"additional","affiliation":[{"name":"Clinique Pasteur b \u00a0 \u00a0 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Brugada","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Hospital Clinic c \u00a0 \u00a0 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2004,1,1]]},"reference":[{"key":"2023122209330098600_b1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1161\/01.CIR.0000088781.99943.95","article-title":"Mapping and ablation of ventricular fibrillation associated with long-QT and Brugada syndromes","volume":"108","author":"Ha\u00efssaguerre","year":"2003","journal-title":"Circulation"},{"key":"2023122209330098600_b2","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/0735-1097(92)90253-J","article-title":"Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome","volume":"20","author":"Brugada","year":"1992","journal-title":"J Am Coll Cardiol"},{"issue":"Suppl","key":"2023122209330098600_b3","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1054\/jelc.2001.28864","article-title":"Catecholamines in children with congenital long QT syndrome and Brugada syndrome","volume":"34","author":"Shimizu","year":"2001","journal-title":"J Electrocardiol"},{"key":"2023122209330098600_b4","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1046\/j.1540-8167.2000.01277.x","article-title":"Infant case with a malignant form of Brugada syndrome","volume":"11","author":"Suzuki","year":"2000","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2023122209330098600_b5","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1540-8159.2000.tb06772.x","article-title":"Near fatal electrical storm in a patient equipped with an implantable cardioverter defibrillator for Brugada syndrome","volume":"23","author":"Chalvidan","year":"2000","journal-title":"Pacing Clin Electrophysiol"},{"key":"2023122209330098600_b6","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1046\/j.1460-9592.2001.01293.x","article-title":"Successful prevention of recurrent ventricular fibrillation by intravenous isoproterenol in a patient with Brugada syndrome","volume":"24","author":"Tanaka","year":"2001","journal-title":"Pacing Clin Electrophysiol"},{"key":"2023122209330098600_b7","first-page":"33","article-title":"Pathogenesis and role of the autonomic nervous system","volume-title":"Clinical approaches to tachyarrhythmias (vol. 10: the Brugada syndrome)","author":"Antzelevitch","year":"1999"},{"key":"2023122209330098600_b8","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0735-1097(95)00613-3","article-title":"Autonomic and antiarrhythmic modulation of ST segment elevation in patients with Brugada syndrome","volume":"27","author":"Miyazaki","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"2023122209330098600_b9","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1161\/01.CIR.95.9.2277","article-title":"Idiopathic ventricular fibrillation induced with vagal activity in patients without obvious heart disease","volume":"95","author":"Kasanuki","year":"1997","journal-title":"Circulation"},{"key":"2023122209330098600_b10","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0735-1097(95)00613-3","article-title":"Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome","volume":"27","author":"Miyazaki","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"2023122209330098600_b11","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/00001573-199905000-00013","article-title":"Ion and channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome","volume":"14","author":"Antzelevitch","year":"1999","journal-title":"Curr Opin Cardiol"},{"key":"2023122209330098600_b12","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1161\/01.CIR.99.5.666","article-title":"\u201cBrugada\u201d syndrome: clinical data and suggested pathophysiological mechanisms","volume":"99","author":"Alings","year":"1999","journal-title":"Circulation"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/6\/2\/130\/54757446\/europace_6_2_130.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/6\/2\/130\/54757446\/europace_6_2_130.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T06:53:31Z","timestamp":1703228011000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/6\/2\/130\/481270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1,1]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,1,1]]}},"URL":"https:\/\/doi.org\/10.1016\/j.eupc.2003.11.009","relation":{},"ISSN":["1532-2092","1099-5129"],"issn-type":[{"value":"1532-2092","type":"electronic"},{"value":"1099-5129","type":"print"}],"subject":[],"published-other":{"date-parts":[[2004,1]]},"published":{"date-parts":[[2004,1,1]]}}}