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This article summarizes the evidence-based major findings and clinical recommendations for the treatment of tobacco dependence of the French Health Products Safety Agency (AFSSAPS). Clinicians should enquire about the smoking status of each patient and provide information about health consequence of smoking and effective treatments available. These treatments include counseling (mainly individual or social support and behavioral and cognitive therapy) and pharmacological treatment with either nicotine replacement therapy (NRT) or bupropion LP. Pharmacological treatments should be used only for proven nicotine dependence, as assessed by the Fagerstrom test for Nicotine Dependence. The choice of pharmacologic treatment depends of the patient's preference and history and of the presence of contra-indications. The clinician should start with a single agent, but these treatments may be used in combination. Smoking behavior is a chronic problem that requires long-term management and follow-up. Access to intensive treatment combining pharmacological treatment and extensive behavioral and cognitive therapy should be available for highly dependent patients.<\/jats:p>","DOI":"10.1016\/j.eurpsy.2004.12.008","type":"journal-article","created":{"date-parts":[[2005,4,8]],"date-time":"2005-04-08T13:19:02Z","timestamp":1112966342000},"page":"431-441","source":"Crossref","is-referenced-by-count":47,"title":["Smoking cessation guidelines: evidence-based recommendations of the French Health Products Safety Agency"],"prefix":"10.1017","volume":"20","author":[{"given":"B.","family":"Le Foll","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Melihan-Cheinin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Rostoker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Lagrue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the working group of AFSSAPS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2020,4,16]]},"reference":[{"key":"S0924933800241412_bib0099","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"S0924933800241412_bib0098","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199103143241106"},{"key":"S0924933800241412_bib0095","volume-title":"Acupuncture for smoking cessation","author":"White","year":"2001"},{"key":"S0924933800241412_bib0093","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)38950-7"},{"key":"S0924933800241412_bib0092","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2000.9521996.x"},{"key":"S0924933800241412_bib0089","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6516.344"},{"key":"S0924933800241412_bib0088","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200216100-00001"},{"key":"S0924933800241412_bib0085","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199631010-00005"},{"key":"S0924933800241412_bib0079","doi-asserted-by":"publisher","DOI":"10.1006\/appe.1994.1014"},{"key":"S0924933800241412_bib0077","doi-asserted-by":"publisher","DOI":"10.1002\/cpt197824140"},{"key":"S0924933800241412_bib0075","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70521-1"},{"key":"S0924933800241412_bib0074","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07369-5"},{"key":"S0924933800241412_bib0071","doi-asserted-by":"publisher","DOI":"10.1016\/S0193-953X(03)00073-X"},{"key":"S0924933800241412_bib0094","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.12.987"},{"key":"S0924933800241412_bib0068","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001055"},{"key":"S0924933800241412_bib0066","first-page":"1S32","article-title":"Les th\u00e9rapies comportementales et cognitives dans l'aide \u00e0 l'arr\u00eat du tabac. 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