{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T09:32:04Z","timestamp":1789896724912,"version":"4.0.1"},"reference-count":52,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T00:00:00Z","timestamp":1586995200000},"content-version":"unspecified","delay-in-days":4764,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. psychiatr."],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0924933800244921_abs1\" sec-type=\"other\"><jats:title>Purpose<\/jats:title><jats:p>The EQ-5D is a generic questionnaire generating a health profile and a single index score for health-related quality of life. This study aimed to analyse the discriminative ability and validity of the EQ-5D in patients with schizophrenic, schizotypal or delusional disorders.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244921_abs2\" sec-type=\"methods\"><jats:title>Subjects and methods<\/jats:title><jats:p>One hundred sixty-six patients with schizophrenic, schizotypal or delusional disorders (ICD-10 F2) completed the EQ-5D. Measures of quality of life (WHOQOL-BREF), utility (TTO), subjective (SCL-90R) and objective (PANSS, CGI-S) psychopathology, and functioning (GAF, GARF, SOFAS, HoNOS) provided comparison. Discriminative ability was analysed by assessing frequency distributions of EQ-5D scores. Validity of the EQ-5D self-classifier was analysed by assessing differences in related other scores grouped by response levels of EQ-5D items. Validity of the visual analogue scale (EQ VAS) and the EQ-5D index (UK social tariff) was analysed by assessing their correlation with all other scores.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244921_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Seventy-nine percent of respondents reported problems in at least one of the EQ-5D dimensions (anxiety\/depression 57%, usual activities 45%, pain\/discomfort 44%, self-care 29%, mobility 22%). The mean EQ VAS score\/EQ-5D index was 65.7\/0.71. The four most frequently reported EQ-5D health states covered 45% of all respondents. For almost all EQ-5D dimensions, different response levels were associated with significantly different scores of measures used for comparison. Correlation of EQ VAS score and EQ-5D index were largest with scores of subjective measures (SCL-90R: \u22120.50 and \u22120.73; WHOQOL mental subscore 0.62 and 0.58; always<jats:italic>P<\/jats:italic>&lt; 0.001).<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244921_abs4\" sec-type=\"conclusions\"><jats:title>Discussion and conclusion<\/jats:title><jats:p>The EQ-5D showed a moderate ceiling effect and seems to be reasonably valid in this patient group.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.eurpsy.2006.08.004","type":"journal-article","created":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T12:11:14Z","timestamp":1165320674000},"page":"177-187","source":"Crossref","is-referenced-by-count":69,"title":["Validity of the EQ-5D in assessing and valuing health status in patients with schizophrenic, schizotypal or delusional disorders"],"prefix":"10.1017","volume":"22","author":[{"given":"Hans-Helmut","family":"K\u00f6nig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Roick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias C.","family":"Angermeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2020,4,16]]},"reference":[{"key":"S0924933800244921_bib50","volume-title":"Measuring quality of life: The development of the\u00a0World Health Organization quality of life Instrument (WHOQOL)","year":"1993"},{"key":"S0924933800244921_bib47","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-004-0689-y"},{"key":"S0924933800244921_bib45","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291798006667"},{"key":"S0924933800244921_bib41","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-834736"},{"key":"S0924933800244921_bib48","first-page":"3","article-title":"Die deutsche Version des Euro-Qol-Fragebogens","volume":"6","author":"von der Schulenburg","year":"1998","journal-title":"Zeitschrift f\u00fcr Gesundheitswissenschaften"},{"key":"S0924933800244921_bib40","doi-asserted-by":"publisher","DOI":"10.1007\/BF00422222"},{"key":"S0924933800244921_bib36","volume-title":"Quality of life and mental health care","author":"Priebe","year":"1999"},{"key":"S0924933800244921_bib35","volume-title":"Health status and health policy","author":"Patrick","year":"1993"},{"key":"S0924933800244921_bib34","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-198903001-00018"},{"key":"S0924933800244921_bib33","first-page":"217","volume-title":"EDCEU assessment in psychopharmacology","author":"Guy","year":"1970"},{"key":"S0924933800244921_bib51","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.172.1.11"},{"key":"S0924933800244921_bib32","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(03)00077-0"},{"key":"S0924933800244921_bib30","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-857991"},{"key":"S0924933800244921_bib29","first-page":"118","article-title":"Messung von Patientenpr\u00e4ferenzen in der Psychiatrie. 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