{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T04:08:54Z","timestamp":1785557334659,"version":"3.56.0"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T00:00:00Z","timestamp":1586908800000},"content-version":"unspecified","delay-in-days":2053,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Health Research Funds from the Spanish Government"},{"name":"European Regional Development Funds"},{"name":"Basque Country Government"},{"DOI":"10.13039\/501100003451","name":"University of the Basque Country","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003451","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Stanley Research Foundation"}],"content-domain":{"domain":["europsy-journal.com","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Eur. psychiatr."],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0924933800244799_abs1\" sec-type=\"other\"><jats:title>Objective<\/jats:title><jats:p>To examine the predictive diagnostic value of affective symptomatology in a first-episode psychosis (FEP) sample with 5 years\u2019 follow-up.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244799_abs2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>Affective dimensions (depressive, manic, activation, dysphoric) were measured at baseline and 5 years in 112 FEP patients based on a factor structure analysis using the Young Mania Rating Scale and Hamilton Depression Rating Scale. Patients were classified as having a diagnosis of bipolar disorder at baseline (BDi), bipolar disorder at 5 years (BDf), or \u201cother psychosis\u201d. The ability of affective dimensions to discriminate between these diagnostic groups and to predict a bipolar disorder diagnosis was analysed.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244799_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Manic dimension score was higher in BDi vs. BDf, and both groups had higher manic and activation scores vs. \u201cother psychosis\u201d. Activation dimension predicted a bipolar diagnosis at 5 years (odds ratio = 1.383; 95% confidence interval, 1.205\u20131.587; <jats:italic>P<\/jats:italic> = 0.000), and showed high levels of sensitivity (86.2%), specificity (71.7%), positive (57.8%) and negative predictive value (90.5%). Absence of the manic dimension and presence of the depressive dimension were both significant predictors of an early misdiagnosis.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244799_abs4\" sec-type=\"conclusions\"><jats:title>Conclusion<\/jats:title><jats:p>The activation dimension is a diagnostic predictor for bipolar disorder in FEP. The manic dimension contributes to a bipolar diagnosis and its absence can lead to early misdiagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.eurpsy.2013.07.005","type":"journal-article","created":{"date-parts":[[2013,9,26]],"date-time":"2013-09-26T13:16:19Z","timestamp":1380201379000},"page":"424-430","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Affective dimensions as a diagnostic tool for bipolar disorder in first psychotic episodes"],"prefix":"10.1017","volume":"29","author":[{"given":"M.","family":"Arrasate","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Gonz\u00e1lez-Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Alberich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Mart\u00ednez-Cengotitabengoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Mosquera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Gonz\u00e1lez-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Gonz\u00e1lez-Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2020,4,15]]},"reference":[{"key":"S0924933800244799_bib0125","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2006.04.008"},{"key":"S0924933800244799_bib0120","doi-asserted-by":"publisher","DOI":"10.1080\/j.1440-1614.2000.00824.x"},{"key":"S0924933800244799_bib0095","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2007.00559.x"},{"key":"S0924933800244799_bib0055","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.56"},{"key":"S0924933800244799_bib0040","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.8.1265"},{"key":"S0924933800244799_bib0075","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/18.3.491"},{"key":"S0924933800244799_bib0030","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.105.017251"},{"key":"S0924933800244799_bib0090","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291799003177"},{"key":"S0924933800244799_bib0165","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700033808"},{"key":"S0924933800244799_bib0050","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00070-8"},{"key":"S0924933800244799_bib0140","volume-title":"Structured Clinical Interview for DSM-IV (SCID I, Version 2.0)","author":"Spitzer","year":"1996"},{"key":"S0924933800244799_bib0135","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.178.6.518"},{"key":"S0924933800244799_bib0020","volume-title":"Diagnostic and Statistical Manual of Mental Disorders. 4th edition (DSM-IV)","year":"1994"},{"key":"S0924933800244799_bib0105","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.2.225"},{"key":"S0924933800244799_bib0035","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199806000-00006"},{"key":"S0924933800244799_bib0025","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-008-0834-7"},{"key":"S0924933800244799_bib0045","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp126"},{"key":"S0924933800244799_bib0115","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbr182"},{"key":"S0924933800244799_bib0145","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1972.01750300011002"},{"key":"S0924933800244799_bib0070","volume-title":"The Positive and Negative Syndrome Scale (PANSS). 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