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During 6-months follow-up, among bipolar disorder patients, polytherapy and serum lipid concentrations declined more than among schizophrenia patients (e.g., total cholesterol + triglycerides, by 3.21 vs 1.75%\/month). BMI remained stable. Declining lipid levels were associated with older age, bipolar disorder, being unemployed, higher antipsychotic doses, and lower initial BPRS scores (all P \u2264 0.001).<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800244751_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Psychotropic treatments were more complex, and metabolic measures more abnormal among bipolar disorder than schizophrenia patients. Intensive psycho-education, clinical monitoring, and encouragement of weight-control for six months were associated with improvements in metabolic measures (but not to BMI), and more realistic attitudes about medication.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.eurpsy.2013.11.005","type":"journal-article","created":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T15:00:48Z","timestamp":1389884448000},"page":"402-407","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Improvements in metabolic abnormalities among overweight schizophrenia and bipolar disorder 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