{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:34:40Z","timestamp":1792499680948,"version":"4.5.0"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2020,3,23]],"date-time":"2020-03-23T00:00:00Z","timestamp":1584921600000},"content-version":"unspecified","delay-in-days":1512,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["europsy-journal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Eur. psychiatr."],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0924933800068073_abst0005\" sec-type=\"other\"><jats:title>Background<\/jats:title><jats:p>The association between body mass index (BMI) and depression is complex and controversial. The present study examined the relationship between BMI and new-onset depression during 7 years of follow-up in 20,212 adult women attending Primary Health Care Centres in Navarra, Spain.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068073_abst0010\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>The Atenci\u00f3n Primaria de Navarra (APNA) study is a dynamic prospective cohort study. A total of 20,212 women aged 18\u201399 years (mean age: 50.7 \u00b1 18.5 years) without depression at baseline were selected from 2004 to 2011. We estimated the incidence of depression. We used the Kaplan-Meier analysis to predict the survival curve. The risk of depression onset according to different measures of BMI at baseline was assessed using Cox regression analyses.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068073_abst0015\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>During the 7 years of follow-up, depression appeared in 8.9% (95% CI 8.5\u20139.3). The highest rates of depression incidence at follow-up occurred in underweight and obese women (9.8% [95% CI 7.3\u201312.9] and 10.3% [95% CI 9.5\u201311.1] respectively). The distribution of depression incidence by weight category was U-shaped. The risk of depression increased over time with an observed Kaplan-Meier estimation of 6.67. After adjusting for age, underweight and obese women at baseline have increased risk of depression onset during the follow-up period compared with normal weight women (HR = 1.48, 95% CI = 1.09\u20132.00 and HR = 1.14, 95% CI = 1.01\u20131.29 respectively).<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068073_abst0020\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>In this 7-year prospective study in the APNA women population, depression emerged in 8.9%. Being underweight or obese (not overweight) at baseline is significantly associated with future onset of depression.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.eurpsy.2015.11.003","type":"journal-article","created":{"date-parts":[[2016,1,21]],"date-time":"2016-01-21T20:32:54Z","timestamp":1453408374000},"page":"55-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Relationship between body mass index and depression in women: A 7-year prospective cohort study. 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