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We further compared connectivity patterns in subgroups of 15 euthymic and 12 non-euthymic patients and tested for correlations of the connectivity strength with measures of mood, anxiety, and rumination tendency. No correction for multiple comparisons was applied given the small population sample and pre-defined target ROIs.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068255_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Overall, regardless of mood state, BD patients exhibited increased FC of the left amygdala with left sgACC and PCC, relative to controls. In addition, non-euthymic BD patients showed distinctive decrease in FC between right amygdala and sgACC, whereas euthymic patients showed lower FC between PCC and sgACC. Euthymic patients also displayed increased FC between sgACC and right VLPFC. The sgACC\u2013PCC and sgACC\u2013left amygdala connections were modulated by rumination tendency in non-euthymic patients, whereas the sgACC-VLPFC connection was modulated by both the current mood and tendency to ruminate.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068255_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that sgACC-amygdala coupling is critically affected during mood episodes, and that FC of sgACC play a pivotal role in mood normalization through its interactions with the VLPFC and PCC. However, these preliminary findings require replication with larger samples of patients.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.eurpsy.2015.12.005","type":"journal-article","created":{"date-parts":[[2016,3,4]],"date-time":"2016-03-04T11:30:28Z","timestamp":1457091028000},"page":"56-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"title":["Resting-state functional connectivity of emotion regulation networks in euthymic and non-euthymic bipolar disorder patients"],"prefix":"10.1017","volume":"34","author":[{"given":"G.","family":"Rey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Piguet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Benders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Favre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SB","family":"Eickhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-M.","family":"Aubry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Vuilleumier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,3,23]]},"reference":[{"key":"S0924933800068255_bib0068","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2009.02030.x"},{"key":"S0924933800068255_bib0065","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2012.01023.x"},{"key":"S0924933800068255_bib0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.05.028"},{"key":"S0924933800068255_bib0066","first-page":"22","article-title":"Neuromodulation for treatment-resistant depression. 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