{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:30:06Z","timestamp":1790062206235,"version":"4.0.1"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2020,3,23]],"date-time":"2020-03-23T00:00:00Z","timestamp":1584921600000},"content-version":"unspecified","delay-in-days":1269,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["europsy-journal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Eur. psychiatr."],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0924933800068735_abs1\" sec-type=\"other\"><jats:title>Background<\/jats:title><jats:p>Mental disorders show varying degrees of continuity from childhood to adulthood. This study addresses the relationship of child and adolescent mental disorders to early adult psychiatric morbidity.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068735_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>From a population at risk of 830,819 children and adolescents aged 6-16 years, we selected all those (<jats:italic>n<\/jats:italic> = 6043) who were enrolled for the first time in the Danish Psychiatric Register with an ICD-10 F00-99 diagnosis in 1995-1997, and identified any mental disorder for which they received treatment up to 2009.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068735_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Neurodevelopmental and conduct disorders were the principal diagnostic groups at 6-16 years and exhibited a characteristic male preponderance; while affective, eating, neurotic, stress-related and adjustment disorders were more common in girls. Over a mean follow-up period of 10.1 years, 1666 (27.6%) cases, mean age 23.4 years, were referred for treatment to mental health services, and they had a markedly higher risk than the general population (RR 5.1; 95% CI 4.9-5.4). Affective, eating, neurodevelopmental, obsessive-compulsive and psychotic disorders had the strongest continuity. Heterotypic transitions were observed for affective, eating, neurodevelopmental, personality and substance use disorders.<\/jats:p><\/jats:sec><jats:sec id=\"S0924933800068735_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>These findings suggest that individuals with psychiatric antecedents in childhood and adolescence had a high risk of being referred for treatment in early adulthood, and many mental disorders for which they required treatment revealed both homotypic and heterotypic continuity.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.eurpsy.2016.04.005","type":"journal-article","created":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T06:17:22Z","timestamp":1474352242000},"page":"45-50","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Early-adult outcome of child and adolescent mental disorders as evidenced by a national-based case register survey"],"prefix":"10.1017","volume":"38","author":[{"given":"A.C.","family":"Castagnini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Foldager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Caffo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.H.","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2020,3,23]]},"reference":[{"key":"S0924933800068735_bib0018","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2014.1893"},{"key":"S0924933800068735_bib0003","first-page":"252","article-title":"Cumulative prevalence of psychiatric disorders by young adulthood: a prospective cohort analysis from the Great Smoky Mountains study","volume":"50","author":"Copeland","year":"2011","journal-title":"J Child Psychol Psychiatry"},{"key":"S0924933800068735_bib0024","doi-asserted-by":"publisher","DOI":"10.1186\/1753-2000-6-40"},{"key":"S0924933800068735_bib0004","first-page":"709","article-title":"Prior juvenile diagnoses in adults with mental disorder","volume":"60","author":"Kim-Cohen","year":"2003","journal-title":"JAMA Psychiatry"},{"key":"S0924933800068735_bib0008","first-page":"764","article-title":"Childhood and adolescent psychiatric disorders as predictors of young adult disorders","volume":"66","author":"Copeland","year":"2009","journal-title":"JAMA Psychiatry"},{"key":"S0924933800068735_bib0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2013.06.004"},{"key":"S0924933800068735_bib0014","volume-title":"The ICD-10 classification of mental and behavioural disorders. 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