{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:50:22Z","timestamp":1758124222712},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.exer.2003.12.005","type":"journal-article","created":{"date-parts":[[2004,4,3]],"date-time":"2004-04-03T10:19:28Z","timestamp":1080987568000},"page":"1155-1162","source":"Crossref","is-referenced-by-count":5,"title":["TIMP-1 role in protection against Pseudomonas aeruginosa-induced corneal destruction"],"prefix":"10.1016","volume":"78","author":[{"given":"Karen A","family":"Kernacki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L","family":"Chunta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald P","family":"Barrett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda D","family":"Hazlett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2003.12.005_BIB1","first-page":"169","article-title":"Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and -2 proteins and mRNA","volume":"183","author":"Ashcroft","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2003.12.005_BIB2","first-page":"20","article-title":"Inhibition of Pseudomonal ulceration in rabbit corneas by a synthetic matrix metalloproteinase inhibitor","volume":"37","author":"Barletta","year":"1996","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB3","series-title":"The Cornea: Transactions of the World Congress on the Cornea 111","first-page":"35","article-title":"The pathogenesis of epithelial defects in stromal ulceration","author":"Berman","year":"1988"},{"key":"10.1016\/j.exer.2003.12.005_BIB4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1755-3768.1992.tb02165.x","article-title":"Collagenolytic\/gelatinolytic enzymes in corneal wound healing","volume":"Suppl. 202","author":"Fini","year":"1992","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.exer.2003.12.005_BIB5","first-page":"579","article-title":"Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury","volume":"65","author":"Fini","year":"1996","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.exer.2003.12.005_BIB6","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.2337\/diabetes.50.5.1047","article-title":"Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells","volume":"50","author":"Han","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.exer.2003.12.005_BIB7","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0307-742X(21)00039-4","article-title":"Ocular complications of rheumatoid arthritis","volume":"3","author":"Hazleman","year":"1977","journal-title":"Clin. Rheum. Disord."},{"key":"10.1016\/j.exer.2003.12.005_BIB8","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1128\/IAI.20.1.25-29.1978","article-title":"Age-related susceptibility to Pseudomonas aeruginosa ocular infections in mice","volume":"20","author":"Hazlett","year":"1978","journal-title":"Infect. Immun."},{"key":"10.1016\/j.exer.2003.12.005_BIB9","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.4049\/jimmunol.149.9.3023","article-title":"IFN-\u03b3 and IL-2 are protective in the skin but pathologic in corneas of HSV-1 infected mice","volume":"149","author":"Hendricks","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2003.12.005_BIB10","first-page":"541","article-title":"Experimental Pseudomonas keratitis","volume":"79","author":"Hyndiuk","year":"1981","journal-title":"Trans. Am. Ophthalmol."},{"key":"10.1016\/j.exer.2003.12.005_BIB11","first-page":"801","article-title":"Development of monoclonal antibodies recognizing collagenase from rabbit PMN; the presence of this enzyme in ulcerating cornea","volume":"11","author":"Kao","year":"1986","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2003.12.005_BIB12","first-page":"610","article-title":"Inflammatory mechanisms in corneal ulceration","volume":"83","author":"Kenyon","year":"1985","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"10.1016\/j.exer.2003.12.005_BIB13","first-page":"292","article-title":"Regeneration of corneal epithelial basement membrane following thermal cauterization","volume":"16","author":"Kenyon","year":"1977","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB14","first-page":"3168","article-title":"Evidence for TIMP-1 protection against P. aeruginosa-induced corneal ulceration and perforation","volume":"40","author":"Kernacki","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB15","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.4049\/jimmunol.164.2.1037","article-title":"Macrophage inflammatory protein-2 is a mediator polymorphonuclear neutrophil influx in ocular bacterial infection","volume":"164","author":"Kernacki","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2003.12.005_BIB16","doi-asserted-by":"crossref","first-page":"6283","DOI":"10.4049\/jimmunol.159.12.6283","article-title":"Association of CD4+ T-cell dependent keratitis with genetic susceptibility to Pseudomonas aeruginosa ocular infection","volume":"159","author":"Kwon","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2003.12.005_BIB17","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1080\/02713689808951266","article-title":"Immunoconfocal localization of gelatinase B expressed by migrating intra stromal epithelial cells after deep annular excimer keratectomy","volume":"17","author":"Maeda","year":"1998","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2003.12.005_BIB18","first-page":"3221","article-title":"Mechanism of basement dissolution preceding corneal ulceration","volume":"32","author":"Matsubara","year":"1991","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB19","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1001\/archopht.1973.01000040398009","article-title":"Epithelium and stroma in alkali-burned corneas","volume":"89","author":"Matsuda","year":"1983","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2003.12.005_BIB20","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0161-6420(00)00590-X","article-title":"The role of matrix metalloproteinases in ulcerative keratolysis associated with perioperative dicofenac use","volume":"108","author":"O'Brien","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2003.12.005_BIB21","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/BF02153659","article-title":"The alkali-burned cornea: electron microscopical, enzyme histochemical and biochemical observations","volume":"223","author":"Pahlitzsch","year":"1985","journal-title":"Graefs Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2003.12.005_BIB22","first-page":"677","article-title":"Recombinant tissue inhibitor of metalloproteinases suppresses alkali-burn-induced corneal ulceration","volume":"35","author":"Paterson","year":"1994","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB23","first-page":"1340","article-title":"Effect of a synthetic metalloproteinase inhibitor or citrate on neutrophil chemotaxis and the respiratory burst","volume":"38","author":"Pfister","year":"1997","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB24","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/(SICI)1097-0177(199708)209:4<367::AID-AJA4>3.0.CO;2-G","article-title":"Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye","volume":"209","author":"Qin","year":"1997","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.exer.2003.12.005_BIB25","first-page":"345","article-title":"Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease","volume":"376","author":"Ries","year":"1995","journal-title":"Biol. Chem. Hoppe-Seyler"},{"key":"10.1016\/j.exer.2003.12.005_BIB26","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/eye.1995.182","article-title":"Collagenase (MMP-1) and TIMP-1 in destructive corneal disease associated with rheumatoid arthritis","volume":"9","author":"Riley","year":"1995","journal-title":"Eye"},{"key":"10.1016\/j.exer.2003.12.005_BIB27","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1076\/ceyr.17.1.47.5247","article-title":"Recombinant TIMP-1 and -2 enhance the proliferation of rabbit corneal epithelial cells in vitro and the spreading of rabbit corneal epithelium in situ","volume":"17","author":"Saika","year":"1998","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2003.12.005_BIB28","first-page":"3325","article-title":"Treatment of alkali-injured rabbit corneas with a synthetic inhibitor of matrix metalloproteinases","volume":"33","author":"Schultz","year":"1992","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB29","first-page":"1461","article-title":"The effects of thermal burn on the release of collagenase from the cornea","volume":"19","author":"Seng","year":"1980","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB30","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1136\/bjo.83.12.1376","article-title":"Role of matrix metalloproteinases in peripheral ulcerative keratitis","volume":"83","author":"Smith","year":"1999","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2003.12.005_BIB31","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0304-4165(89)90008-1","article-title":"Characterization of corneal proteoglycans under vitamin A deficiency","volume":"992","author":"Twining","year":"1989","journal-title":"Biochem. Biophys. Acta"},{"key":"10.1016\/j.exer.2003.12.005_BIB32","first-page":"2174","article-title":"Effect of a metalloproteinase inhibitor on established corneal ulcers","volume":"33","author":"Wentworth","year":"1992","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2003.12.005_BIB33","doi-asserted-by":"crossref","first-page":"37258","DOI":"10.1074\/jbc.M106089200","article-title":"The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B\/MMP-9 and neutrophil associated-lipocalin (NGAL)","volume":"276","author":"Yan","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exer.2003.12.005_BIB34","first-page":"13","article-title":"Expression of gelatinases A and B, and TIMPs 1 and 2 during corneal wound healing","volume":"39","author":"Ye","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483503004111?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483503004111?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T21:05:33Z","timestamp":1705093533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483503004111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S0014483503004111"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2003.12.005","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}