{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:26:55Z","timestamp":1789993615237,"version":"4.0.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.exer.2007.10.004","type":"journal-article","created":{"date-parts":[[2007,10,29]],"date-time":"2007-10-29T16:36:39Z","timestamp":1193675799000},"page":"138-149","source":"Crossref","is-referenced-by-count":49,"title":["High-efficacy site-directed drug delivery system using sialyl-Lewis X conjugated liposome"],"prefix":"10.1016","volume":"86","author":[{"given":"Noriyasu","family":"Hashida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Ohguro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noboru","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Arakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Oiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Mashimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuo","family":"Kurokawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Tano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2007.10.004_bib1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0167-0115(02)00059-9","article-title":"Immunochemical characterization and measurement of neuronal type nitric oxide synthase in human neuroblastoma NB-OK-1 cell using novel anti-synthetic peptide antibody and specific immunoassay system","volume":"106","author":"Arakawa","year":"2002","journal-title":"Regul. Pept."},{"key":"10.1016\/j.exer.2007.10.004_bib2","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/humu.20065","article-title":"Real-time quantitative PCR as a routine method for screening large rearrangements in Rett syndrome: Report of one case of MECP2 deletion and one case of MECP2 duplication","volume":"24","author":"Ariani","year":"2004","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.exer.2007.10.004_bib3","first-page":"127","article-title":"Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype","volume":"41","author":"Avichezer","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2007.10.004_bib4","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1002\/eji.1830241215","article-title":"Only simultaneous blocking of the L- and P-selectin completely inhibits neutrophil migration into mouse peritoneum","volume":"24","author":"Bosse","year":"1994","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.exer.2007.10.004_bib5","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0031-6997(24)01426-1","article-title":"Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors","volume":"51","author":"Drummond","year":"1999","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.exer.2007.10.004_bib6","doi-asserted-by":"crossref","first-page":"14863","DOI":"10.1073\/pnas.95.25.14863","article-title":"Cluster analysis and display of genome-wide expression patterns","volume":"95","author":"Eisen","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.exer.2007.10.004_bib7","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1083\/jcb.117.4.895","article-title":"The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis (x) oligosaccharide","volume":"117","author":"Foxall","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2007.10.004_bib8","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1023\/A:1013033826974","article-title":"Preferential binding of polyethylene glycol-coated liposomes containing a novel cationic lipid, TRX-20, to human subendothelial cells via chondroitin sulfate","volume":"18","author":"Harigai","year":"2001","journal-title":"Pharm. Res."},{"key":"10.1016\/j.exer.2007.10.004_bib9","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1167\/iovs.05-0346","article-title":"Microarray analysis of cytokine and chemokine gene expression after prednisolone treatment in murine experimental autoimmune uveoretinitis","volume":"46","author":"Hashida","year":"2005","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2007.10.004_bib10","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.bbrc.2006.12.060","article-title":"Accumulation of liposome with sialyl Lewis X to inflammation and tumor region: Application to in vivo bio-imaging","volume":"353","author":"Hirai","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exer.2007.10.004_bib11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00417-002-0556-x","article-title":"Chemokine and chemokine receptor expression during experimental autoimmune uveoretinitis in mice","volume":"241","author":"Keino","year":"2003","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2007.10.004_bib12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0005-2736(01)00368-6","article-title":"Investigation of the cellular uptake of E-Selectin-targeted immunoliposomes by activated human endothelial cells","volume":"1514","author":"Kessner","year":"2001","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.exer.2007.10.004_bib13","first-page":"4282","article-title":"Novel chondroitin sulfate-binding cationic liposomes loaded with cisplatin efficiently suppress the local growth and liver metastasis of tumor cells in vivo","volume":"62","author":"Lee","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.exer.2007.10.004_bib14","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1084\/jem.181.2.669","article-title":"Sequential contribution of L- and P-selectin to leukocyte rolling in vivo","volume":"181","author":"Ley","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.exer.2007.10.004_bib15","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/0955-0674(92)90109-P","article-title":"Leukocyte-endothelial cell interactions","volume":"4","author":"McEver","year":"1992","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.exer.2007.10.004_bib16","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.4049\/jimmunol.165.6.2962","article-title":"Amelioration of experimental autoimmune uveoretinitis by pretreatment with a pathogenic peptide in liposome and anti-CD40 ligand monoclonal antibody","volume":"165","author":"Namba","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2007.10.004_bib17","doi-asserted-by":"crossref","first-page":"E36","DOI":"10.1093\/nar\/30.9.e36","article-title":"Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR","volume":"30","author":"Pfaffl","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.exer.2007.10.004_bib18","doi-asserted-by":"crossref","first-page":"6224","DOI":"10.1073\/pnas.88.14.6224","article-title":"CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis X","volume":"88","author":"Polley","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.exer.2007.10.004_bib19","doi-asserted-by":"crossref","first-page":"8795","DOI":"10.1073\/pnas.94.16.8795","article-title":"Immunotargeting of liposomes to activated vascular endothelial cells:\u00a0A strategy for site-selective delivery in the cardiovascular system","volume":"94","author":"Spragg","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.exer.2007.10.004_bib20","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/PL00000774","article-title":"Sialyl Lewis (x)-liposomes as vehicles for site-directed, E-selectin-mediated drug transfer into activated endothelial cells","volume":"58","author":"Stahn","year":"2001","journal-title":"Cell. Mol. Life. Sci."},{"key":"10.1016\/j.exer.2007.10.004_bib21","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/jgm.358","article-title":"Antibody targeted gene transfer to endothelium","volume":"5","author":"Tan","year":"2003","journal-title":"J. Gene Med."},{"key":"10.1016\/j.exer.2007.10.004_bib22","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1046\/j.1365-2249.1997.4571356.x","article-title":"Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animals","volume":"109","author":"Thurau","year":"1997","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.exer.2007.10.004_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1615\/CritRevTherDrugCarrierSyst.v18.i1.10","article-title":"Ligand-receptor-mediated drug delivery: an emerging paradigm in cellular drug targeting","volume":"18","author":"Vyas","year":"2001","journal-title":"Crit. Rev. Ther. Drug Carrier. Syst."},{"key":"10.1016\/j.exer.2007.10.004_bib24","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0169-409X(97)00083-5","article-title":"Ligand-targeted liposomes","volume":"29","author":"Willis","year":"1998","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.exer.2007.10.004_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.bbamem.2003.10.014","article-title":"Effect of sialyl Lewis X-glycoliposomes on the inhibition of E-selectin-mediated tumour cell adhesion in vitro","volume":"1660","author":"Zeisig","year":"2004","journal-title":"Biochim. Biophys. Acta"}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483507002977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483507002977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:25:02Z","timestamp":1737505502000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483507002977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0014483507002977"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2007.10.004","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}