{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:22:07Z","timestamp":1790853727819,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.exer.2009.01.018","type":"journal-article","created":{"date-parts":[[2009,2,11]],"date-time":"2009-02-11T12:27:33Z","timestamp":1234355253000},"page":"1124-1128","source":"Crossref","is-referenced-by-count":20,"title":["IL-10 promotor haplotypes associated with susceptibility to and severity of bacterial corneal ulcers"],"prefix":"10.1016","volume":"88","author":[{"given":"S.","family":"Keijser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.A.S.","family":"Kurreeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.J.W.","family":"de Keizer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Dogterom-Ballering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"van der Lelij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Jager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.H.","family":"Nibbering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2009.01.018_bib1","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1128\/IAI.71.3.1328-1336.2003","article-title":"Experimental Pseudomonas aeruginosa keratitis in interleukin-10 gene knockout mice","volume":"71","author":"Cole","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.exer.2009.01.018_bib2","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1002\/1529-0131(199909)42:9<2017::AID-ANR34>3.0.CO;2-I","article-title":"Single nucleotide polymorphic haplotypes of the interleukin-10 5\u2032 flanking region are not associated with renal disease or serology in Caucasian patients with systemic lupus erythematosus","volume":"42","author":"Crawley","year":"1999","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.exer.2009.01.018_bib4","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1136\/thorax.58.2.154","article-title":"Association of IL-10 polymorphism with severity of illness in community acquired pneumonia","volume":"58","author":"Gallagher","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.exer.2009.01.018_bib5","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1046\/j.1365-2249.2002.01999.x","article-title":"Interleukin-10 ameliorates the outcome of Staphylococcus aureus arthritis by promoting bacterial clearance","volume":"130","author":"Gjertsson","year":"2002","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.exer.2009.01.018_bib6","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1080\/00365540110077218","article-title":"Polymorphism of the IL-10 gene is associated with susceptibility to herpes zoster","volume":"34","author":"Haanpaa","year":"2002","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.exer.2009.01.018_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2003.10.002","article-title":"Corneal response to Pseudomonas aeruginosa infection","volume":"23","author":"Hazlett","year":"2004","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2009.01.018_bib8","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1167\/iovs.06-0882","article-title":"Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection","volume":"48","author":"Hazlett","year":"2007","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2009.01.018_bib9","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1086\/314883","article-title":"Polymorphism of the interleukin-10 gene is associated with susceptibility to Epstein\u2013Barr virus infection","volume":"180","author":"Helminen","year":"1999","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.exer.2009.01.018_bib10","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1086\/322987","article-title":"Susceptibility to primary Epstein\u2013Barr virus infection is associated with interleukin-10 gene promoter polymorphism","volume":"184","author":"Helminen","year":"2001","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.exer.2009.01.018_bib11","doi-asserted-by":"crossref","first-page":"4626","DOI":"10.1167\/iovs.07-0316","article-title":"ST2 is essential for Th2 responsiveness and resistance to Pseudomonas aeruginosa keratitis","volume":"48","author":"Huang","year":"2007","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2009.01.018_bib12","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1440-1711.2005.01326.x","article-title":"A Staphylococcus aureus mouse keratitis topical infection model: cytokine balance in different strains of mice","volume":"83","author":"Hume","year":"2005","journal-title":"Immunol. Cell Biol."},{"issue":"Suppl. 1","key":"10.1016\/j.exer.2009.01.018_bib13","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1002\/jmv.10320","article-title":"IL-10 gene polymorphism and herpesvirus infections","volume":"70","author":"Hurme","year":"2003","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.exer.2009.01.018_bib3","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0198-8859(02)00369-5","article-title":"Frequency of functional interleukin-10 promoter polymorphism is different between relapse-onset and primary progressive multiple sclerosis","volume":"63","author":"de Jong","year":"2002","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.exer.2009.01.018_bib14","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.1167\/iovs.06-0564","article-title":"Factors affecting the morbidity of contact lens-related microbial keratitis: a population study","volume":"47","author":"Keay","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2009.01.018_bib15","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1093\/hmg\/ddh187","article-title":"Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level","volume":"13","author":"Kurreeman","year":"2004","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.exer.2009.01.018_bib16","doi-asserted-by":"crossref","first-page":"5219","DOI":"10.4049\/jimmunol.170.10.5219","article-title":"Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB\/c mice","volume":"170","author":"McClellan","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2009.01.018_bib17","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1111\/j.1572-0241.2002.05926.x","article-title":"Influence of interleukin-10 gene promoter polymorphisms on disease progression in patients chronically infected with hepatitis B virus","volume":"97","author":"Miyazoe","year":"2002","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.exer.2009.01.018_bib18","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1007\/s00251-003-0543-3","article-title":"Interleukin-10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population","volume":"54","author":"Moraes","year":"2003","journal-title":"Immunogenetics"},{"key":"10.1016\/j.exer.2009.01.018_bib19","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/sj.gene.6364182","article-title":"Risk of trachomatous scarring and trichiasis in Gambians varies with SNP haplotypes at the interferon-gamma and interleukin-10 loci","volume":"6","author":"Natividad","year":"2005","journal-title":"Genes Immun."},{"key":"10.1016\/j.exer.2009.01.018_bib20","series-title":"Diseases of the External Eye and Adnexa","first-page":"137","article-title":"Disease of the cornea","author":"Ostler","year":"1993"},{"key":"10.1016\/j.exer.2009.01.018_bib21","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1164\/rccm.200210-1164OC","article-title":"Pneumococcal septic shock is associated with the interleukin-10-1082 gene promoter polymorphism","volume":"168","author":"Schaaf","year":"2003","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.exer.2009.01.018_bib22","doi-asserted-by":"crossref","first-page":"14467","DOI":"10.1073\/pnas.97.26.14467","article-title":"Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10","volume":"97","author":"Shin","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.exer.2009.01.018_bib23","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1161\/01.RES.87.6.448","article-title":"Antiangiogenic effect of interleukin-10 in ischemia-induced angiogenesis in mice hindlimb","volume":"87","author":"Silvestre","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.exer.2009.01.018_bib24","first-page":"349","article-title":"Association of IL2, TNFA, IL4 and IL10 promoter gene polymorphisms with the rate of progression of the HIV infection","volume":"7","author":"Smolnikova","year":"2002","journal-title":"Russ. J. Immunol."},{"key":"10.1016\/j.exer.2009.01.018_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2370.1997.tb00001.x","article-title":"An investigation of polymorphism in the interleukin-10 gene promoter","volume":"24","author":"Turner","year":"1997","journal-title":"Eur. J. Immunogenet."},{"key":"10.1016\/j.exer.2009.01.018_bib26","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/90868","article-title":"Optimizing human fertility and survival","volume":"7","author":"Westendorp","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.exer.2009.01.018_bib27","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1189\/jlb.69.1.149","article-title":"Autocrine action of IL-10 suppresses proinflammatory mediators and inflammation in the HSV-1-infected cornea","volume":"69","author":"Yan","year":"2001","journal-title":"J. Leukoc. Biol."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483509000323?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483509000323?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T23:23:11Z","timestamp":1684884191000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483509000323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S0014483509000323"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2009.01.018","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}