{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:12:28Z","timestamp":1784304748695,"version":"3.55.0"},"reference-count":56,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.exer.2011.06.001","type":"journal-article","created":{"date-parts":[[2011,6,25]],"date-time":"2011-06-25T23:16:09Z","timestamp":1309043769000},"page":"424-436","source":"Crossref","is-referenced-by-count":22,"title":["Retinal proliferation response in the buphthalmic zebrafish, bugeye"],"prefix":"10.1016","volume":"93","author":[{"given":"Tshering","family":"Sherpa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel S.","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth A.","family":"Frey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barrie D.","family":"Robison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah L.","family":"Stenkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2011.06.001_bib1","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1177\/38.9.2201738","article-title":"Improved method for obtaining 3-microns cryosections for immunocytochemistry","volume":"38","author":"Barthel","year":"1990","journal-title":"J.\u00a0Histochem. Cytochem."},{"key":"10.1016\/j.exer.2011.06.001_bib3","doi-asserted-by":"crossref","first-page":"7028","DOI":"10.1523\/JNEUROSCI.1624-07.2007","article-title":"Late-stage neuronal progenitors in the retina are radial Muller glia that function as retinal stem cells","volume":"27","author":"Bernardos","year":"2007","journal-title":"J.\u00a0Neurosci."},{"issue":"4","key":"10.1016\/j.exer.2011.06.001_bib56","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.cbpa.2010.07.016","article-title":"Zebrafish (Danio rerio) vary by strain and sex in their behavioral and transcriptional responses to selenium supplementation","volume":"157","author":"Benner","year":"2010","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"issue":"suppl. 1","key":"10.1016\/j.exer.2011.06.001_bib4","doi-asserted-by":"crossref","first-page":"D842","DOI":"10.1093\/nar\/gkq1008","article-title":"The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics","volume":"39","author":"Blake","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.exer.2011.06.001_bib5","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1242\/dev.120.9.2409","article-title":"Selective regeneration of photoreceptors in goldfish retina","volume":"120","author":"Braisted","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.exer.2011.06.001_bib6","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1017\/S0952523800175121","article-title":"Cellular proliferation and neurogenesis in the injured retina of adult zebrafish","volume":"17","author":"Cameron","year":"2000","journal-title":"Vis. Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib7","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1523\/JNEUROSCI.15-03-02255.1995","article-title":"Cone photoreceptor regeneration in adult fish retina: phenotypic determination and mosaic pattern formation","volume":"15","author":"Cameron","year":"1995","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib8","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/ajmg.1320470518","article-title":"Diaphragmatic hernia, exomphalos, absent corpus callosum, hypertelorism, myopia, and sensorineural deafness: a newly recognized autosomal recessive disorder?","volume":"47","author":"Donnai","year":"1993","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.exer.2011.06.001_bib9","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1016\/0042-6989(86)90135-5","article-title":"The myopic eye of the Black Moor goldfish","volume":"26","author":"Easter","year":"1986","journal-title":"Vision. Res."},{"key":"10.1016\/j.exer.2011.06.001_bib10","doi-asserted-by":"crossref","first-page":"6303","DOI":"10.1523\/JNEUROSCI.0332-06.2006","article-title":"A\u00a0role for alpha1 tubulin-expressing Muller glia in regeneration of the injured zebrafish retina","volume":"26","author":"Fausett","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib11","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1523\/JNEUROSCI.4853-07.2008","article-title":"The proneural basic helix-loop-helix gene ascl1a is required for retina regeneration","volume":"28","author":"Fausett","year":"2008","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib13","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1523\/JNEUROSCI.5317-06.2007","article-title":"Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish","volume":"27","author":"Fimbel","year":"2007","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib14","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.ydbio.2006.06.007","article-title":"The role of megalin (LRP-2\/Gp330) during development","volume":"296","author":"Fisher","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.exer.2011.06.001_bib15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/neu.480230209","article-title":"Local regeneration in the retina of the goldfish","volume":"23","author":"Hitchcock","year":"1992","journal-title":"J.\u00a0Neurobiol."},{"key":"10.1016\/j.exer.2011.06.001_bib16","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.preteyeres.2004.01.001","article-title":"Persistent and injury-induced neurogenesis in the vertebrate retina","volume":"23","author":"Hitchcock","year":"2004","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2011.06.001_bib17","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1002\/bimj.200810425","article-title":"Simultaneous inference in general parametric models","volume":"50","author":"Hothorn","year":"2008","journal-title":"Biometrical J."},{"key":"10.1016\/j.exer.2011.06.001_bib18","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1167\/iovs.06-0606","article-title":"Hsp27 phosphorylation in experimental glaucoma","volume":"48","author":"Huang","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2011.06.001_bib20","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.neuroscience.2007.09.078","article-title":"The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model","volume":"150","author":"Kalesnykas","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.exer.2011.06.001_bib21","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1038\/ng2063","article-title":"Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes","volume":"39","author":"Kantarci","year":"2007","journal-title":"Nat. Genet."},{"key":"10.1016\/j.exer.2011.06.001_bib22","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1002\/dneu.20362","article-title":"Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish","volume":"67","author":"Kassen","year":"2007","journal-title":"Dev. Neurobiol."},{"issue":"3","key":"10.1016\/j.exer.2011.06.001_bib57","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1017\/S0952523807070423","article-title":"Mechanisms for persistent microphthalmia following ethanol exposure during retinal neurogenesis in zebrafish embryos","volume":"24","author":"Kashyap","year":"2007","journal-title":"Vis Neurosci"},{"key":"10.1016\/j.exer.2011.06.001_bib23","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3940(96)13021-4","article-title":"Zebrafish elav\/HuC homologue as a very early neuronal marker","volume":"216","author":"Kim","year":"1996","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.exer.2011.06.001_bib24","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1002\/dvdy.22624","article-title":"Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development","volume":"240","author":"Kur","year":"2011","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.exer.2011.06.001_bib25","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1242\/dev.109.3.567","article-title":"Early onset of phenotype and cell patterning in the embryonic zebrafish retina","volume":"109","author":"Larison","year":"1990","journal-title":"Development"},{"key":"10.1016\/j.exer.2011.06.001_bib26","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF00239223","article-title":"Regeneration of the goldfish retina after exposure to different doses of ouabain","volume":"202","author":"Maier","year":"1979","journal-title":"Cell. Tissue. Res."},{"key":"10.1016\/j.exer.2011.06.001_bib27","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1017\/S095252389916303X","article-title":"Neurogenesis in the visual system of embryonic and adult zebrafish (Danio rerio). off","volume":"16","author":"Marcus","year":"1999","journal-title":"Vis. Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib28","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.exer.2008.12.002","article-title":"Mouse models of retinal ganglion cell death and glaucoma","volume":"88","author":"McKinnon","year":"2009","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2011.06.001_bib29","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1017\/S0952523899162059","article-title":"Visual function in regenerating teleost retina following cytotoxic lesioning","volume":"16","author":"Mensinger","year":"1999","journal-title":"Vis. Neurosci."},{"key":"10.1016\/j.exer.2011.06.001_bib30","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1002\/cne.22243","article-title":"A\u00a0novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors","volume":"518","author":"Montgomery","year":"2010","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.exer.2011.06.001_bib31","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/dneu.20610","article-title":"Genetic dissection reveals two separate pathways for rod and cone regeneration in the teleost retina","volume":"68","author":"Morris","year":"2008","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.exer.2011.06.001_bib32","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1016\/0921-8696(88)90006-0","article-title":"Immunohistochemical and autoradiographic studies on retinal regeneration in teleost fish","volume":"8","author":"Negishi","year":"1988","journal-title":"Neurosci. Res. Suppl."},{"key":"10.1016\/j.exer.2011.06.001_bib2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s12035-010-8143-3","article-title":"HspB1 (Hsp27) expression and neuroprotection in the retina","volume":"42","author":"O\u2019Reilly","year":"2010","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.exer.2011.06.001_bib33","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1139\/Z08-085","article-title":"Strain-specific alteration of zebrafish feeding behavior in response to aversive stimuli","volume":"86","author":"Oswald","year":"2008","journal-title":"Can. J. Zoology-Revue Canadienne De Zoologie"},{"key":"10.1016\/j.exer.2011.06.001_bib34","doi-asserted-by":"crossref","first-page":"9310","DOI":"10.1073\/pnas.0811186106","article-title":"Genetic evidence for shared mechanisms of epimorphic regeneration in zebrafish","volume":"106","author":"Qin","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.exer.2011.06.001_bib36","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0161-6420(88)33176-3","article-title":"Chronic human glaucoma causing selectively greater loss of large optic nerve fibers","volume":"95","author":"Quigley","year":"1988","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2011.06.001_bib37","first-page":"774","article-title":"Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis","volume":"36","author":"Quigley","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2011.06.001_bib59","series-title":"A Language and Environment for Statistical Computing","author":"R Core Development Team","year":"2006"},{"key":"10.1016\/j.exer.2011.06.001_bib38","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/cne.902760207","article-title":"Neuronal cell proliferation and ocular enlargement in Black Moor goldfish","volume":"276","author":"Raymond","year":"1988","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.exer.2011.06.001_bib39","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/dneu.20568","article-title":"Ganglion cell regeneration following whole-retina destruction in zebrafish","volume":"68","author":"Sherpa","year":"2008","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.exer.2011.06.001_bib40","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1001\/archopht.1991.01080010079037","article-title":"Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss","volume":"109","author":"Sommer","year":"1991","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2011.06.001_bib41","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0074-7696(06)59005-9","article-title":"Neurogenesis in the fish retina","volume":"259","author":"Stenkamp","year":"2007","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/j.exer.2011.06.001_bib42","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/1096-9861(20010319)431:4<363::AID-CNE1076>3.0.CO;2-7","article-title":"Evidence for two distinct mechanisms of neurogenesis and cellular pattern formation in regenerated goldfish retinas","volume":"431","author":"Stenkamp","year":"2001","journal-title":"J.\u00a0Comp. Neurol."},{"issue":"3","key":"10.1016\/j.exer.2011.06.001_bib60","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/dvdy.10165","article-title":"Embryonic retinal gene expression in sonic-you mutant zebrafish","volume":"225","author":"Stenkamp","year":"2002","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.exer.2011.06.001_bib43","doi-asserted-by":"crossref","first-page":"4631","DOI":"10.1167\/iovs.07-1224","article-title":"Age-related cone abnormalities in zebrafish with genetic lesions in sonic hedgehog","volume":"49","author":"Stenkamp","year":"2008","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"7","key":"10.1016\/j.exer.2011.06.001_bib44","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.1167\/iovs.10-6434","article-title":"The bugeye mutant zebrafish exhibits visual deficits that arise with the onset of an enlarged eye phenotype","volume":"52","author":"Stujenske","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2011.06.001_bib45","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1001\/archopht.118.4.511","article-title":"Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes","volume":"118","author":"Tezel","year":"2000","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2011.06.001_bib46","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/dneu.20596","article-title":"Inhibition of Muller glial cell division blocks regeneration of the light-damaged zebrafish retina","volume":"68","author":"Thummel","year":"2008","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.exer.2011.06.001_bib47","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0896-6273(90)90194-K","article-title":"Organization of hindbrain segments in the zebrafish embryo","volume":"4","author":"Trevarrow","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/j.exer.2011.06.001_bib48","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s12192-009-0105-1","article-title":"Hsp27 is persistently expressed in zebrafish skeletal and cardiac muscle tissues but dispensable for their morphogenesis","volume":"14","author":"Tucker","year":"2009","journal-title":"Cell. Stress. Chaperones."},{"key":"10.1016\/j.exer.2011.06.001_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1001310","article-title":"Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma","volume":"7","author":"Veth","year":"2011","journal-title":"PLoS Genet."},{"key":"10.1016\/j.exer.2011.06.001_bib50","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/1097-4695(20000905)44:3<289::AID-NEU1>3.0.CO;2-H","article-title":"Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina","volume":"44","author":"Vihtelic","year":"2000","journal-title":"J.\u00a0Neurobiol."},{"key":"10.1016\/j.exer.2011.06.001_bib51","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.exer.2005.08.015","article-title":"Retinal regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish","volume":"82","author":"Vihtelic","year":"2006","journal-title":"Exp. Eye Res."},{"issue":"Suppl. 1","key":"10.1016\/j.exer.2011.06.001_bib52","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1038\/sj.eye.6702880","article-title":"The neurobiology of cell death in glaucoma","volume":"21","author":"Vrabec","year":"2007","journal-title":"Eye (London, England)"},{"key":"10.1016\/j.exer.2011.06.001_bib53","doi-asserted-by":"crossref","first-page":"8460","DOI":"10.1073\/pnas.93.16.8460","article-title":"Defective forebrain development in mice lacking gp330\/megalin","volume":"93","author":"Willnow","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.exer.2011.06.001_bib54","first-page":"2115","article-title":"Cones regenerate from retinal stem cells sequestered in the inner nuclear layer of adult goldfish retina","volume":"42","author":"Wu","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2011.06.001_bib55","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.visres.2004.10.022","article-title":"Responses of Muller glia to retinal injury in adult zebrafish","volume":"45","author":"Yurco","year":"2005","journal-title":"Vision. Res."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483511001680?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483511001680?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T19:40:48Z","timestamp":1637955648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483511001680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":56,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0014483511001680"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2011.06.001","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}