{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:55:41Z","timestamp":1791147341885,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.exer.2012.07.011","type":"journal-article","created":{"date-parts":[[2012,8,20]],"date-time":"2012-08-20T21:48:44Z","timestamp":1345499324000},"page":"55-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":69,"special_numbering":"C","title":["Aqueous humor oxidative stress proteomic levels in primary open angle glaucoma"],"prefix":"10.1016","volume":"103","author":[{"given":"A.","family":"Bagnis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Izzotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Centofanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.C.","family":"Sacc\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2012.07.011_bib1","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/S0161-6420(84)34248-8","article-title":"Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals","volume":"91","author":"Alvarado","year":"1984","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2012.07.011_bib2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.lungcan.2005.02.006","article-title":"Comparative application of antibody and gene array for expression profiling in human squamous cell lung carcinoma","volume":"49","author":"Bartling","year":"2005","journal-title":"Lung Cancer"},{"key":"10.1016\/j.exer.2012.07.011_bib3","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1097\/00061198-199910000-00010","article-title":"How does the trabecular meshwork regulate outflow? Clues from the vascular endothelium","volume":"8","author":"Brandt","year":"1999","journal-title":"J.\u00a0Glaucoma"},{"key":"10.1016\/j.exer.2012.07.011_bib4","first-page":"321061","article-title":"Nitric oxide synthase enzymes in the airways of mice exposed to ovalbumin: NOS2 expression is NOS3 dependent","author":"Bratt","year":"2010","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.exer.2012.07.011_bib5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0014-4835(86)90029-1","article-title":"Analysis of human aqueous humor by high resolution 1H NMR spectroscopy","volume":"42","author":"Brown","year":"1986","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/01.ijg.0000195932.48288.97","article-title":"Enhanced Glaucoma Staging System (GGS2) for classifying functional damage in glaucoma","volume":"15","author":"Brusini","year":"2006","journal-title":"J.\u00a0Glaucoma"},{"key":"10.1016\/j.exer.2012.07.011_bib7","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.ejca.2007.11.025","article-title":"Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays","volume":"44","author":"Carlsson","year":"2008","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.exer.2012.07.011_bib8","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S1350-9462(98)00026-3","article-title":"Differential gene expression in the human ciliary epithelium","volume":"18","author":"Coca Prados","year":"1999","journal-title":"Prog. Ret. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.preteyeres.2007.01.002","article-title":"New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland","volume":"26","author":"Coca-Prados","year":"2007","journal-title":"Prog. Ret. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib10","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/j.1749-6632.1994.tb21792.x","article-title":"Molecular mechanisms of nitric oxide actions in the brain","volume":"738","author":"Dawson","year":"1994","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib11","first-page":"103","article-title":"Mechanism of action of glutathione-dependent enzymes","volume":"59","author":"Douglas","year":"1987","journal-title":"Adv. Enzymol. Relat. Areas Mol. Biol."},{"key":"10.1016\/j.exer.2012.07.011_bib12","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1001\/archopht.1996.01100130295012","article-title":"Elevated glutamate in the vitreous body o f humans and monkeys with glaucoma","volume":"114","author":"Dreyer","year":"1996","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib13","first-page":"370","article-title":"Proteomic analysis of aqueous humor from patients with myopia","volume":"14","author":"Duan","year":"2008","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2012.07.011_bib14","doi-asserted-by":"crossref","first-page":"5817","DOI":"10.1167\/iovs.09-5072","article-title":"Endogenous regulation of human Schlemm's canal cell volume by nitric oxide signaling","volume":"51","author":"Ellis","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib15","doi-asserted-by":"crossref","first-page":"14818","DOI":"10.1074\/jbc.274.21.14818","article-title":"The heparin binding domain of extracellular superoxide dismutase is proteolytically processed intracellularly during biosynthesis","volume":"274","author":"Enghild","year":"1999","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.exer.2012.07.011_bib16","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0002-9394(03)00788-8","article-title":"Oxidative stress markers in aqueous humor of glaucoma patients","volume":"137","author":"Ferreira","year":"2004","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib17","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1038\/eye.2008.352","article-title":"Antioxidant status in the aqueous humor of patients with glaucoma associated with exfoliation syndrome","volume":"23","author":"Ferreira","year":"2009","journal-title":"Eye"},{"key":"10.1016\/j.exer.2012.07.011_bib18","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.exer.2009.01.005","article-title":"Modulation of extracellular matrix turnover in the trabecular meshwork","volume":"88","author":"Fuchshofer","year":"2009","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib19","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.exer.2004.10.001","article-title":"Cl\u2212 concentrations of bovine, porcine and ovine aqueous humor are higher than in plasma","volume":"80","author":"Gerometta","year":"2005","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib20","doi-asserted-by":"crossref","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","article-title":"Glutathione S-transferases. The first enzymatic step in mercapturic acid formation","volume":"249","author":"Habig","year":"1974","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.exer.2012.07.011_bib21","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1177\/002215540305101014","article-title":"Expression and localization of vesicular glutamate transporters in pancreatic islet, upper gastrointestinal tracts, and testis","volume":"51","author":"Hayashi","year":"2003","journal-title":"J.\u00a0Histochem. Cytochem."},{"key":"10.1016\/j.exer.2012.07.011_bib22","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.1016\/S0039-6257(99)00026-0","article-title":"Potential role of nitric oxide and endothelin in the pathogenesis of glaucoma","volume":"43","author":"Haefliger","year":"1997","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib23","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.mrrev.2005.11.001","article-title":"The role of oxidative stress in glaucoma","volume":"612","author":"Izzotti","year":"2006","journal-title":"Mutat. Res."},{"key":"10.1016\/j.exer.2012.07.011_bib24","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/sj.eye.6702737","article-title":"Antioxidant activity of timolol on endothelial cells and its relevance for glaucoma course","volume":"22","author":"Izzoti","year":"2008","journal-title":"Eye (Lond.)"},{"key":"10.1016\/j.exer.2012.07.011_bib25","doi-asserted-by":"crossref","first-page":"5251","DOI":"10.1167\/iovs.09-3871","article-title":"Sensitivity of ocular anterior chamber tissues to oxidative damage and its relevance to the pathogenesis of glaucoma","volume":"50","author":"Izzotti","year":"2009","journal-title":"Invest. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib26","doi-asserted-by":"crossref","first-page":"4831","DOI":"10.1021\/pr1005372","article-title":"Proteome alterations in primary open angle glaucoma aqueous humor","volume":"9","author":"Izzotti","year":"2010","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.exer.2012.07.011_bib27","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1001\/archophthalmol.2010.87","article-title":"Mitochondrial damage in the trabecular meshwork of patients with glaucoma","volume":"128","author":"Izzotti","year":"2010","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib28","doi-asserted-by":"crossref","first-page":"e20110","DOI":"10.1371\/journal.pone.0020110","article-title":"Trabecular meshwork gene expression after selective laser trabeculoplasty","volume":"6","author":"Izzotti","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2012.07.011_bib29","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0005-2728(99)00020-1","article-title":"Nitric oxide metabolism and breakdown","volume":"1411","author":"Kelm","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.exer.2012.07.011_bib30","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.exer.2004.07.008","article-title":"Growth factor in the anterior segment: role in tissue maintenance, wound healing and ocular pathology","volume":"79","author":"Klenkler","year":"2004","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib31","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/(SICI)1098-1136(200004)30:2<178::AID-GLIA7>3.0.CO;2-C","article-title":"Expression of nitric oxide synthase-(NOS-2) in reactive astrocytes of the human glaucomatous optic nerve head","volume":"30","author":"Liu","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.exer.2012.07.011_bib32","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1074\/mcp.M700006-MCP200","article-title":"A\u00a0proteomics analysis of cell signaling alterations in colorectal cancer","volume":"6","author":"Madoz-G\u00farpide","year":"2007","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.exer.2012.07.011_bib33","doi-asserted-by":"crossref","first-page":"C1117","DOI":"10.1152\/ajpcell.00444.2004","article-title":"Iron alters glutamate secretion by regulating cytosolic aconitase activity","volume":"288","author":"McGahan","year":"2005","journal-title":"Am. J. Physiol. Cell. Physiol."},{"key":"10.1016\/j.exer.2012.07.011_bib34","first-page":"3589","article-title":"Na(+)-dependent glutamate transporter in human retinal pigment epithelial cells","volume":"35","author":"Miyamoto","year":"1994","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib35","first-page":"1765","article-title":"Identification of an extensive system of nitric oxide \u2013 producing cells in the ciliary muscle and outflow pathways of the human eye","volume":"36","author":"Nathason","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib36","doi-asserted-by":"crossref","first-page":"11193","DOI":"10.1158\/0008-5472.CAN-05-1436","article-title":"Antibody microarray profiling reveals individual and combined serum proteins associated with pancreatic cancer","volume":"65","author":"Orchekowski","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.exer.2012.07.011_bib37","doi-asserted-by":"crossref","first-page":"653","DOI":"10.2147\/OPTH.S10922","article-title":"Free radicals in the aqueous humor of patients with glaucoma","volume":"4","author":"Oshida","year":"2010","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib38","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S0006-291X(88)81362-7","article-title":"l-Arginine is the physiological precursor for the formation of nitric oxide in endothelium dependent relaxation","volume":"153","author":"Palmer","year":"1988","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exer.2012.07.011_bib39","first-page":"807108","article-title":"Mitochondrial DNA damage and animal longevity: insights from comparative studies","author":"Pamplona","year":"2011","journal-title":"J.\u00a0Aging Res."},{"key":"10.1016\/j.exer.2012.07.011_bib40","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1016\/j.visres.2007.07.011","article-title":"Expression of neuronal nitric oxide synthase in the retina of rat model of chronic glaucoma","volume":"47","author":"Park","year":"2007","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2012.07.011_bib41","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1016\/S0042-6989(98)00069-8","article-title":"Water soluble antioxidants in mammalian aqueous humor: interaction with UVB and hydrogen peroxide","volume":"38","author":"Richer","year":"1998","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2012.07.011_bib42","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/bjo.85.1.24","article-title":"Daily tonometric curves after cataract surgery","volume":"85","author":"Sacc\u00e0","year":"2001","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib43","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1001\/archopht.123.4.458","article-title":"Oxidative damage in the human trabecular meshwork: clinical correlation in patient with primary open-angle glaucoma","volume":"123","author":"Sacc\u00e0","year":"2005","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib44","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.exer.2006.10.008","article-title":"Glaucomatous outflow pathway and oxidative stress","volume":"84","author":"Sacc\u00e0","year":"2007","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib45","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0079-6123(08)01127-8","article-title":"Oxidative stress and glaucoma: injury in the anterior segment of the eye","volume":"173","author":"Sacc\u00e0","year":"2008","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.exer.2012.07.011_bib46","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.mrfmmm.2008.11.002","article-title":"Gene\u2013environment interactions in ocular diseases","volume":"667","author":"Sacc\u00e0","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1016\/j.exer.2012.07.011_bib47","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1001\/archophthalmol.2010.324","article-title":"Ability of dorzolamide hydrochloride and timolol maleate to target mitochondria in glaucoma therapy","volume":"129","author":"Sacc\u00e0","year":"2011","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib48","doi-asserted-by":"crossref","first-page":"4242","DOI":"10.1167\/iovs.11-8902","article-title":"New proteins as vascular biomarkers in primary open angle glaucomatous aqueous humor","volume":"53","author":"Sacc\u00e0","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib49","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1373\/clinchem.2005.059592","article-title":"Antibody arrays: technical considerations and clinical applications in cancer","volume":"52","author":"Sanchez-Carbayo","year":"2006","journal-title":"Clin. Chem."},{"key":"10.1016\/j.exer.2012.07.011_bib50","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00417-003-0638-4","article-title":"Elevation of nitric oxide production in human trabecular meshwork by increased pressure","volume":"241","author":"Scheneemann","year":"2003","journal-title":"Graefe's Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2012.07.011_bib51","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/pros.20514","article-title":"Antibody array profiling reveals serum TSP-1 as a marker to distinguish benign from malignant prostatic disease","volume":"67","author":"Shafer","year":"2007","journal-title":"Prostate"},{"key":"10.1016\/j.exer.2012.07.011_bib52","first-page":"2884","article-title":"Isoforms of nitric oxide synthase in the optic nerves of rat eyes with chronic moderately elevated intraocular pressure","volume":"40","author":"Shareef","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib53","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1167\/iovs.03-0948","article-title":"Glutamate-induced glutamine synthetase expression in retinal Muller cells after short-term ocular hypertension in the rat","volume":"45","author":"Shen","year":"2004","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib54","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0014-4835(81)80107-8","article-title":"Hydrogen peroxide and human cataract","volume":"33","author":"Spector","year":"1981","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2012.07.011_bib55","first-page":"1188","article-title":"The aqueous humor is capable of generating and degrading H2O2","volume":"39","author":"Spector","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib56","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1111\/j.1474-9726.2010.00622.x","article-title":"Comparing the yeast retrograde response and NF-\u03baB stress responses: implications for aging","volume":"9","author":"Srinivasan","year":"2010","journal-title":"Aging Cell."},{"key":"10.1016\/j.exer.2012.07.011_bib57","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/j.0300-9475.2004.01432.x","article-title":"Circulating cytokines in primary Sj\u00f6gren's syndrome determined by a multiplex cytokine array system","volume":"59","author":"Szodoray","year":"2004","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.exer.2012.07.011_bib58","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/rheumatology\/kel306","article-title":"Circulating cytokines in Norwegian patients with psoriatic arthritis determined by a multiplex cytokine array system","volume":"46","author":"Szodoray","year":"2007","journal-title":"Rheumatology (Oxf.)"},{"key":"10.1016\/j.exer.2012.07.011_bib59","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1444-0938.2002.tb02384.x","article-title":"The mechanism of aqueous humor formation","volume":"85","author":"To","year":"2002","journal-title":"Clin. Exp. Optom."},{"key":"10.1016\/j.exer.2012.07.011_bib60","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1089\/ars.2007.1957","article-title":"Redox regulation of cell survival","volume":"10","author":"Trachootham","year":"2008","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.exer.2012.07.011_bib61","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1079\/BJN20041113","article-title":"Functional dichotomy: glutathione and vitamin E in homeostasis relevant to primary open-angle glaucoma","volume":"91","author":"Veach","year":"2004","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.exer.2012.07.011_bib62","first-page":"99","article-title":"Oxidative stress in the trabecular meshwork of POAG","volume":"227","author":"Welge-L\u00fcssen","year":"2010","journal-title":"Klin. Monbl. Augenheilkd."},{"key":"10.1016\/j.exer.2012.07.011_bib63","first-page":"334","article-title":"The influence of visible light exposure on cultured RGC-5 cells","volume":"14","author":"Wood","year":"2007","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2012.07.011_bib64","first-page":"1273","article-title":"Serum autoantibody against glutathione S-transferase in patients with glaucoma","volume":"42","author":"Yang","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib65","doi-asserted-by":"crossref","first-page":"4872","DOI":"10.1167\/iovs.07-0984","article-title":"Effects of oxidative stress in trabecular meshwork cells are reduced by prostaglandin analogues","volume":"49","author":"Yu","year":"2008","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2012.07.011_bib66","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.visres.2004.11.018","article-title":"Effect of hypercholesterolemia on inducible nitric oxide synthase expression in a rat model of elevated intraocular pressure","volume":"45","author":"Yucel","year":"2005","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2012.07.011_bib67","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1002\/(SICI)1097-4652(199908)180:2<182::AID-JCP6>3.0.CO;2-X","article-title":"Oxidative stress affects cytoskeletal structure and cell-matrix interactions in cells from an ocular tissue: the trabecular meshwork","volume":"180","author":"Zhou","year":"1999","journal-title":"J.\u00a0Cell. Physiol."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483512002448?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483512002448?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:26:56Z","timestamp":1762147616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483512002448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":67,"alternative-id":["S0014483512002448"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2012.07.011","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aqueous humor oxidative stress proteomic levels in primary open angle glaucoma","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2012.07.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}