{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T02:46:27Z","timestamp":1774579587238,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1016\/j.exer.2014.07.026","type":"journal-article","created":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T17:36:38Z","timestamp":1408124198000},"page":"243-251","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Expression of the lymphatic marker podoplanin (D2-40) in human fetal eyes"],"prefix":"10.1016","volume":"127","author":[{"given":"Martina C.","family":"Herwig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"M\u00fcnstermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Klarmann-Schulz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona L.","family":"Schlereth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludwig M.","family":"Heindl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin U.","family":"Loeffler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette M.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2014.07.026_bib1","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1136\/bjo.2006.092080","article-title":"Endothelial cell proliferation in the choriocapillaris during human retinal differentiation","volume":"90","author":"Allende","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2014.07.026_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1413.001","article-title":"Markers for microscopic imaging of lymphangiogenesis and angiogenesis","volume":"1131","author":"Baluk","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib3","first-page":"61","article-title":"Selective D2-40 lymphatic endothelium immunoreactivity in developing human fetal skin appendages","volume":"42","author":"Bellin","year":"2009","journal-title":"Lymphology"},{"key":"10.1016\/j.exer.2014.07.026_bib4","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1167\/iovs.08-3307","article-title":"Expression of podoplanin and other lymphatic markers in the human anterior eye segment","volume":"51","author":"Birke","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib5","first-page":"102","article-title":"The anatomy of fetal peripheral lymphatic vessels in the head-and-neck region: an immunohistochemical study","volume":"220","author":"Cho","year":"2012","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.exer.2014.07.026_bib6","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1097\/01.ico.0000214230.21238.3d","article-title":"Absence of blood and lymphatic vessels in the developing human cornea","volume":"25","author":"Cursiefen","year":"2006","journal-title":"Cornea"},{"key":"10.1016\/j.exer.2014.07.026_bib7","first-page":"2127","article-title":"Lymphatic vessels in vascularized human corneas: immunohistochemical investigation using LYVE-1 and podoplanin","volume":"43","author":"Cursiefen","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib8","first-page":"681","article-title":"Observation of lymphatic vessels in orbital fat of patients with inflammatory conditions: a form fruste of lymphangiogenesis?","volume":"13","author":"Fogt","year":"2004","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.exer.2014.07.026_bib9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/01.iop.0000249431.04116.a8","article-title":"D2-40 expression demonstrates lymphatic vessel characteristics in the dural portion of the optic nerve sheath","volume":"23","author":"Gausas","year":"2007","journal-title":"Ophthal. Plast. Reconstr. Surg."},{"key":"10.1016\/j.exer.2014.07.026_bib10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/01.dad.0000249885.11195.15","article-title":"Cutaneous immunoreactivity of D2-40 antibody beyond the lymphatics","volume":"29","author":"Gomaa","year":"2007","journal-title":"Am. J. Dermatopathol."},{"key":"10.1016\/j.exer.2014.07.026_bib11","first-page":"128","article-title":"Specific role of lymphatic marker podoplanin in retinal pigment epithelial cells","volume":"43","author":"Grimaldo","year":"2010","journal-title":"Lymphology"},{"key":"10.1016\/j.exer.2014.07.026_bib12","doi-asserted-by":"crossref","first-page":"8849","DOI":"10.1167\/iovs.11-7591","article-title":"Histopathology of the trabecular meshwork and Schlemm's canal in primary angle-closure glaucoma","volume":"52","author":"Hamanaka","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib13","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1001\/archophthalmol.2010.143","article-title":"Intraocular lymphatics in ciliary body melanomas with extraocular extension: functional for lymphatic spread?","volume":"128","author":"Heindl","year":"2010","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2014.07.026_bib14","first-page":"1217","article-title":"Vascularization of the human fetal retina: roles of vasculogenesis and angiogenesis","volume":"41","author":"Hughes","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2535\/ofaj.87.1","article-title":"A\u00a0comparison between D2-40 and c-KIT immunohistochemistry for the human fetal testis and ovary at the second trimester of gestation","volume":"87","author":"Jin","year":"2010","journal-title":"Okajimas Folia Anat. Jpn."},{"key":"10.1016\/j.exer.2014.07.026_bib16","first-page":"671","article-title":"Fetal anatomy of peripheral lymphatic vessels: a D2-40 immunohistochemical study using an 18-week human fetus (CRL 155 mm)","volume":"216","author":"Jin","year":"2010","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.exer.2014.07.026_bib17","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/modpathol.3880543","article-title":"Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas","volume":"15","author":"Kahn","year":"2002","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.exer.2014.07.026_bib18","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1038\/labinvest.2011.121","article-title":"Regressed lymphatic vessels develop during corneal repair","volume":"91","author":"Kelley","year":"2011","journal-title":"Lab. Invest."},{"key":"10.1016\/j.exer.2014.07.026_bib19","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1369\/jhc.2008.950840","article-title":"Does immunohistochemistry allow easy detection of lymphatics in the optic nerve sheath?","volume":"56","author":"Killer","year":"2008","journal-title":"J.\u00a0Histochem. Cytochem."},{"key":"10.1016\/j.exer.2014.07.026_bib20","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/01.pas.0000213388.47913.f1","article-title":"Podoplanin is a highly sensitive and specific marker to distinguish primary skin adnexal carcinomas from adenocarcinomas metastatic to skin","volume":"31","author":"Liang","year":"2007","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.exer.2014.07.026_bib21","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2334\/josnusd.51.283","article-title":"The significance of podoplanin expression in human inflamed gingiva","volume":"51","author":"Miyazaki","year":"2009","journal-title":"J.\u00a0Oral Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib22","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/modpathol.3800616","article-title":"D2-40 antibody immunoreactivity in developing human brain, brain tumors and cultured neural cells","volume":"19","author":"Nakamura","year":"2006","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.exer.2014.07.026_bib23","doi-asserted-by":"crossref","first-page":"783163","DOI":"10.1155\/2012\/783163","article-title":"Lymphatics and lymphangiogenesis in the eye","volume":"2012","author":"Nakao","year":"2012","journal-title":"J.\u00a0Ophthalmol."},{"key":"10.1016\/j.exer.2014.07.026_bib24","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1442-9071.2007.01549.x","article-title":"Lymphangiogenesis concurrent with haemangiogenesis in the human cornea","volume":"35","author":"Regina","year":"2007","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2014.07.026_bib25","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0002-9440(10)62311-5","article-title":"Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors","volume":"166","author":"Schacht","year":"2005","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.exer.2014.07.026_bib26","doi-asserted-by":"crossref","first-page":"5222","DOI":"10.1167\/iovs.08-1721","article-title":"The normal human choroid is endowed with a significant number of lymphatic vessel endothelial hyaluronate receptor 1 (LYVE-1)-positive macrophages","volume":"49","author":"Schroedl","year":"2008","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib27","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/BF02153410","article-title":"Ultrastructure of the human posterior tunica vasculosa lentis during early gestation","volume":"225","author":"Sellheyer","year":"1987","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2014.07.026_bib28","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.tice.2010.11.003","article-title":"Podoplanin is expressed by a sub-population of human foetal rib and knee joint rudiment chondrocytes","volume":"43","author":"Smith","year":"2011","journal-title":"Tissue & Cell."},{"key":"10.1016\/j.exer.2014.07.026_bib29","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1167\/iovs.08-3279","article-title":"Involvement of platelet coagulation and inflammation in the endothelium of Schlemm's canal","volume":"51","author":"Watanabe","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib30","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.1167\/iovs.12-9507","article-title":"Invasion of lymphatic vessels into the eye after open globe injuries","volume":"53","author":"Wessel","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib31","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1167\/iovs.06-0783","article-title":"LYVE-1-positive macrophages are present in normal murine eyes","volume":"48","author":"Xu","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2014.07.026_bib32","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.exer.2009.08.010","article-title":"Identification of lymphatics in the ciliary body of the human eye: a novel \u201cuveolymphatic\u201d outflow pathway","volume":"89","author":"Yucel","year":"2009","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2014.07.026_bib33","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1006\/exer.2000.0844","article-title":"The human hyaloid system: cell death and vascular regression","volume":"70","author":"Zhu","year":"2000","journal-title":"Exp. Eye Res."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448351400219X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448351400219X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,30]],"date-time":"2018-09-30T15:50:29Z","timestamp":1538322629000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001448351400219X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":33,"alternative-id":["S001448351400219X"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2014.07.026","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of the lymphatic marker podoplanin (D2-40) in human fetal eyes","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2014.07.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}