{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T01:36:16Z","timestamp":1777340176028,"version":"3.51.4"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["16K11290"],"award-info":[{"award-number":["16K11290"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17H04351"],"award-info":[{"award-number":["17H04351"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.exer.2018.02.019","type":"journal-article","created":{"date-parts":[[2018,2,24]],"date-time":"2018-02-24T07:26:44Z","timestamp":1519457204000},"page":"160-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells"],"prefix":"10.1016","volume":"170","author":[{"given":"Kei-Ichi","family":"Nakashima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichiro","family":"Iwao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7935-5896","authenticated-orcid":false,"given":"Akira","family":"Haga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Tsutsumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyuki Inoue","family":"Mochita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4867-1925","authenticated-orcid":false,"given":"Tomokazu","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidenobu","family":"Tanihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2018.02.019_bib1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jneuroim.2014.10.006","article-title":"Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy","volume":"277","author":"Ahmad","year":"2014","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.exer.2018.02.019_bib2","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jneuroim.2013.09.015","article-title":"Potential role of A2A adenosine receptor in traumatic optic neuropathy","volume":"264","author":"Ahmad","year":"2013","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.exer.2018.02.019_bib3","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/sj.bjp.0704267","article-title":"A(1)-, A(2A)- and A(3)-subtype adenosine receptors modulate intraocular pressure in the mouse","volume":"134","author":"Avila","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.exer.2018.02.019_bib4","first-page":"3021","article-title":"Knockout of A3 adenosine receptors reduces mouse intraocular pressure","volume":"43","author":"Avila","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.02.019_bib5","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.ophtha.2009.11.029","article-title":"Treatment of dry eye syndrome with orally administered CF101: data from a phase 2 clinical trial","volume":"117","author":"Avni","year":"2010","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2018.02.019_bib6","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/0896-6273(88)90127-4","article-title":"Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning","volume":"1","author":"Barres","year":"1988","journal-title":"Neuron"},{"key":"10.1016\/j.exer.2018.02.019_bib7","doi-asserted-by":"crossref","first-page":"29626","DOI":"10.1074\/jbc.273.45.29626","article-title":"Axon outgrowth is regulated by an intracellular purine-sensitive mechanism in retinal ganglion cells","volume":"273","author":"Benowitz","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exer.2018.02.019_bib9","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0026-895X(25)10259-9","article-title":"Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes","volume":"29","author":"Bruns","year":"1986","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.exer.2018.02.019_bib10","doi-asserted-by":"crossref","first-page":"4731","DOI":"10.1523\/JNEUROSCI.21-13-04731.2001","article-title":"Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate","volume":"21","author":"Cai","year":"2001","journal-title":"J. Neurosci. : Off. J. Soc. Neurosci."},{"key":"10.1016\/j.exer.2018.02.019_bib11","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0002-9394(98)00272-4","article-title":"The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Collaborative Normal-Tension Glaucoma Study Group","volume":"126","year":"1998","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.exer.2018.02.019_bib12","doi-asserted-by":"crossref","first-page":"7734","DOI":"10.1523\/JNEUROSCI.5288-11.2012","article-title":"Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth","volume":"32","author":"Corredor","year":"2012","journal-title":"J. Neurosci. :Off. J. Soc. Neurosci."},{"key":"10.1016\/j.exer.2018.02.019_bib13","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/35037600","article-title":"Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor","volume":"407","author":"Corset","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.exer.2018.02.019_bib14","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0022-3565(25)09553-9","article-title":"Adenosine receptor activation modulates intraocular pressure in rabbits","volume":"273","author":"Crosson","year":"1995","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.exer.2018.02.019_bib15","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1159\/000309344","article-title":"Do patients with low tension glaucoma have particular cardiovascular characteristics? Ophthalmologica. Journal international d'ophtalmologie","volume":"188","author":"Demailly","year":"1984","journal-title":"Int. J. Ophthalmol. Zeitschrift fur Augenheilkunde"},{"key":"10.1016\/j.exer.2018.02.019_bib16","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.1242\/jcs.034082","article-title":"Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons","volume":"121","author":"Diaz-Hernandez","year":"2008","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.exer.2018.02.019_bib17","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1111\/j.1476-5381.1996.tb15561.x","article-title":"Tissue distribution of adenosine receptor mRNAs in the rat","volume":"118","author":"Dixon","year":"1996","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.exer.2018.02.019_bib19","doi-asserted-by":"crossref","first-page":"15859","DOI":"10.1523\/JNEUROSCI.0038-12.2012","article-title":"Ectopic vesicular glutamate release at the optic nerve head and axon loss in mouse experimental glaucoma","volume":"32","author":"Fu","year":"2012","journal-title":"J. Neurosci. : Off. J. Soc. Neurosci."},{"key":"10.1016\/j.exer.2018.02.019_bib20","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.exer.2015.08.009","article-title":"Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration","volume":"140","author":"Galvao","year":"2015","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2018.02.019_bib21","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1124\/mol.59.1.76","article-title":"A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis","volume":"59","author":"Gao","year":"2001","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.exer.2018.02.019_bib22","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1167\/iovs.12-10218","article-title":"Series length used during trend analysis affects sensitivity to changes in progression rate in the ocular hypertension treatment study","volume":"54","author":"Gardiner","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.02.019_bib23","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0304-3940(88)90547-2","article-title":"Adenosine reduces cortical neuronal injury induced by oxygen or glucose deprivation in vitro","volume":"89","author":"Goldberg","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.exer.2018.02.019_bib24","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0301-0082(01)00011-9","article-title":"The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling","volume":"65","author":"Grimes","year":"2001","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.exer.2018.02.019_bib25","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/bjo.78.6.449","article-title":"Optic nerve head blood flow using a laser Doppler velocimeter and haemorheology in primary open angle glaucoma and normal pressure glaucoma","volume":"78","author":"Hamard","year":"1994","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2018.02.019_bib26","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1172\/JCI30178","article-title":"The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma","volume":"117","author":"Harada","year":"2007","journal-title":"J. Clin. Invest."},{"issue":"120","key":"10.1016\/j.exer.2018.02.019_bib27","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1001\/archopht.120.10.1268","article-title":"Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial","volume":"1960","author":"Heijl","year":"2002","journal-title":"Arch. Ophthalmo. Chicago, Ill"},{"key":"10.1016\/j.exer.2018.02.019_bib28","first-page":"1641","article-title":"The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study","volume":"111","author":"Iwase","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2018.02.019_bib29","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.ophtha.2010.10.016","article-title":"Prevalence of primary open-angle glaucoma in central South Korea the Namil study","volume":"118","author":"Kim","year":"2011","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2018.02.019_bib30","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0169-328X(02)00550-8","article-title":"Activation of protein kinase A induces neuronal differentiation of HiB5 hippocampal progenitor cells. Brain research","volume":"109","author":"Kim","year":"2002","journal-title":"Mol. Brain Res."},{"key":"10.1016\/j.exer.2018.02.019_bib31","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1006\/exer.1996.0352","article-title":"Localization of adenosine receptor messenger RNAs in the rat eye","volume":"65","author":"Kvanta","year":"1997","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2018.02.019_bib32","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1471-4159.2007.04756.x","article-title":"Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo","volume":"103","author":"Lingor","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.exer.2018.02.019_bib34","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.trsl.2015.11.005","article-title":"Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure-induced transient ischemic injury","volume":"169","author":"Madeira","year":"2016","journal-title":"Transl. Res. : J. Lab. Clin. Med."},{"key":"10.1016\/j.exer.2018.02.019_bib35","doi-asserted-by":"crossref","first-page":"10494","DOI":"10.1523\/JNEUROSCI.0148-11.2011","article-title":"Involvement of caspase-6 and caspase-8 in neuronal apoptosis and the regenerative failure of injured retinal ganglion cells","volume":"31","author":"Monnier","year":"2011","journal-title":"J. Neurosci. :Off. J. Soc. Neurosci."},{"key":"10.1016\/j.exer.2018.02.019_bib36","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0014-4886(03)00311-X","article-title":"Intraocular injection of dibutyryl cyclic AMP promotes axon regeneration in rat optic nerve","volume":"186","author":"Monsul","year":"2004","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.exer.2018.02.019_bib37","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/328175a0","article-title":"Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene","volume":"328","author":"Montminy","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.exer.2018.02.019_bib38","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1126\/science.1175737","article-title":"KLF family members regulate intrinsic axon regeneration ability","volume":"326","author":"Moore","year":"2009","journal-title":"Science (New York, N.Y)"},{"key":"10.1016\/j.exer.2018.02.019_bib39","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1254\/jphs.95.124","article-title":"Calcineurin contributes to the enhancing effect of adenosine on nerve growth factor-induced neurite outgrowth via the decreased duration of p38 mitogen-activated protein kinase phosphorylation","volume":"95","author":"Muroi","year":"2004","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.exer.2018.02.019_bib40","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/j.ophtha.2004.02.017","article-title":"Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study","volume":"111","author":"Nouri-Mahdavi","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2018.02.019_bib41","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.cellimm.2009.03.020","article-title":"The anti-inflammatory target A(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn's disease","volume":"258","author":"Ochaion","year":"2009","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.exer.2018.02.019_bib42","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1080\/02713680490522443","article-title":"Adenosine protects cultured retinal neurons against NMDA-induced cell death through A1 receptors","volume":"29","author":"Oku","year":"2004","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2018.02.019_bib43","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1126\/science.1161566","article-title":"Promoting axon regeneration in the adult CNS by modulation of the PTEN\/mTOR pathway","volume":"322","author":"Park","year":"2008","journal-title":"Science (New York, N.Y)"},{"key":"10.1016\/j.exer.2018.02.019_bib45","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0896-6273(02)00730-4","article-title":"Spinal axon regeneration induced by elevation of cyclic AMP","volume":"34","author":"Qiu","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.exer.2018.02.019_bib46","first-page":"774","article-title":"Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis","volume":"36","author":"Quigley","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.02.019_bib47","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2018.02.019_bib48","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.ophtha.2009.06.058","article-title":"Cerebrospinal fluid pressure in glaucoma: a prospective study","volume":"117","author":"Ren","year":"2010","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2018.02.019_bib49","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1007\/s00429-015-1072-1","article-title":"Axonal elongation and dendritic branching is enhanced by adenosine A2A receptors activation in cerebral cortical neurons","volume":"221","author":"Ribeiro","year":"2016","journal-title":"Brain Struct. Funct."},{"issue":"120","key":"10.1016\/j.exer.2018.02.019_bib50","first-page":"471","article-title":"Glaucoma in Zulus: a population-based cross-sectional survey in a rural district in South Africa. Archives of ophthalmology","volume":"1960","author":"Rotchford","year":"2002","journal-title":"Chicago, Ill"},{"issue":"109","key":"10.1016\/j.exer.2018.02.019_bib52","first-page":"1090","article-title":"Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. The Baltimore Eye Survey. Archives of ophthalmology","volume":"1960","author":"Sommer","year":"1991","journal-title":"Chicago, Ill."},{"key":"10.1016\/j.exer.2018.02.019_bib53","doi-asserted-by":"crossref","first-page":"10515","DOI":"10.1073\/pnas.1509879112","article-title":"In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS","volume":"112","author":"Takihara","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"112","key":"10.1016\/j.exer.2018.02.019_bib54","first-page":"69","article-title":"Family history and risk of primary open angle glaucoma. The Baltimore Eye Survey. Archives of ophthalmology","volume":"1960","author":"Tielsch","year":"1994","journal-title":"Chicago, Ill."},{"issue":"113","key":"10.1016\/j.exer.2018.02.019_bib55","first-page":"216","article-title":"Hypertension, perfusion pressure, and primary open-angle glaucoma. A population-based assessment. Archives of ophthalmology","volume":"1960","author":"Tielsch","year":"1995","journal-title":"Chicago, Ill."},{"key":"10.1016\/j.exer.2018.02.019_bib56","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1111\/j.1471-4159.1979.tb05236.x","article-title":"Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells","volume":"33","author":"van Calker","year":"1979","journal-title":"J. Neurochem."},{"key":"10.1016\/j.exer.2018.02.019_bib57","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0006-8993(98)00713-6","article-title":"Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells","volume":"809","author":"Vitolo","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.exer.2018.02.019_bib58","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.cell.2004.11.012","article-title":"GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity","volume":"120","author":"Yoshimura","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.exer.2018.02.019_bib59","first-page":"937","article-title":"Identification of the A3 adenosine receptor in rat retinal ganglion cells","volume":"12","author":"Zhang","year":"2006","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2018.02.019_bib60","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.neuint.2009.08.011","article-title":"The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells","volume":"56","author":"Zhang","year":"2010","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.exer.2018.02.019_bib61","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1471-4159.2006.03900.x","article-title":"Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation","volume":"98","author":"Zhang","year":"2006","journal-title":"J. Neurochem."},{"key":"10.1016\/j.exer.2018.02.019_bib62","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0925-4439(99)00111-8","article-title":"A role for the A3 adenosine receptor in determining tissue levels of cAMP and blood pressure: studies in knock-out mice","volume":"1500","author":"Zhao","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.exer.2018.02.019_bib63","doi-asserted-by":"crossref","first-page":"7432","DOI":"10.1073\/pnas.89.16.7432","article-title":"Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor","volume":"89","author":"Zhou","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483517306693?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483517306693?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:32:20Z","timestamp":1751416340000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483517306693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":58,"alternative-id":["S0014483517306693"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2018.02.019","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2018.02.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}