{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:37:16Z","timestamp":1790743036613,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,9,17]],"date-time":"2019-09-17T00:00:00Z","timestamp":1568678400000},"content-version":"am","delay-in-days":320,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["EY026635"],"award-info":[{"award-number":["EY026635"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["EY011386"],"award-info":[{"award-number":["EY011386"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.exer.2018.09.002","type":"journal-article","created":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T00:10:22Z","timestamp":1536365422000},"page":"243-251","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis"],"prefix":"10.1016","volume":"176","author":[{"given":"Yaping","family":"Ju","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikanth Reddy","family":"Janga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wannita","family":"Klinngam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3626-1654","authenticated-orcid":false,"given":"J. Andrew","family":"MacKay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dillon","family":"Hawley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1622-4431","authenticated-orcid":false,"given":"Driss","family":"Zoukhri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Edman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah F.","family":"Hamm-Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2018.09.002_bib1","doi-asserted-by":"crossref","first-page":"5218","DOI":"10.1167\/iovs.15-17003","article-title":"Role of matrix metalloproteinases 2 and 9 in lacrimal gland disease in animal models of Sjogren's syndrome","volume":"56","author":"Aluri","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.09.002_bib2","first-page":"3134543","article-title":"Delivery of bone marrow-derived mesenchymal stem cells improves tear production in a mouse model of Sjogren's syndrome","volume":"2017","author":"Aluri","year":"2017","journal-title":"Stem Cell. Int."},{"key":"10.1016\/j.exer.2018.09.002_bib3","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1146\/annurev.immunol.23.021704.115643","article-title":"The NOD mouse: a model of immune dysregulation","volume":"23","author":"Anderson","year":"2005","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.exer.2018.09.002_bib4","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/dc.21544","article-title":"The cell with a thousand faces: detection of myoepithelial cells and their contributions in the cytological diagnosis of salivary gland tumors","volume":"40","author":"Avci","year":"2012","journal-title":"Diagn. Cytopathol."},{"key":"10.1016\/j.exer.2018.09.002_bib5","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1210\/edrv-15-4-516","article-title":"Insulin-dependent diabetes mellitus as an autoimmune disease","volume":"15","author":"Bach","year":"1994","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.exer.2018.09.002_bib6","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1002\/art.30500","article-title":"Changes in Rab3D expression and distribution in the acini of Sjogren's syndrome patients are associated with loss of cell polarity and secretory dysfunction","volume":"63","author":"Bahamondes","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.exer.2018.09.002_bib7","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1093\/rheumatology\/34.3.226","article-title":"Interferon-gamma and epithelial cell activation in Sjogren's syndrome","volume":"34","author":"Brookes","year":"1995","journal-title":"Br. J. Rheumatol."},{"key":"10.1016\/j.exer.2018.09.002_bib8","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/S1079-2104(96)80443-4","article-title":"Myoepithelial cells actively proliferate during atrophy of rat parotid gland","volume":"82","author":"Burgess","year":"1996","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"10.1016\/j.exer.2018.09.002_bib9","doi-asserted-by":"crossref","first-page":"18002","DOI":"10.1074\/jbc.M201248200","article-title":"Dominant negative Rab3D inhibits amylase release from mouse pancreatic acini","volume":"277","author":"Chen","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exer.2018.09.002_bib10","doi-asserted-by":"crossref","first-page":"w13042","DOI":"10.4414\/smw.2010.13042","article-title":"Cathepsins and their involvement in immune responses","volume":"140","author":"Conus","year":"2010","journal-title":"Swiss Med. Wkly."},{"key":"10.1016\/j.exer.2018.09.002_bib11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.preteyeres.2009.04.003","article-title":"Neural regulation of lacrimal gland secretory processes: relevance in dry eye diseases","volume":"28","author":"Dartt","year":"2009","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2018.09.002_bib12","doi-asserted-by":"crossref","first-page":"23561","DOI":"10.1038\/srep23561","article-title":"Altered mucosal microbiome diversity and disease Severity in Sjogren syndrome","volume":"6","author":"de Paiva","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.exer.2018.09.002_bib13","doi-asserted-by":"crossref","first-page":"5961","DOI":"10.4049\/jimmunol.1300551","article-title":"Accelerated turnover of MHC class II molecules in nonobese diabetic mice is developmentally and environmentally regulated in vivo and dispensable for autoimmunity","volume":"190","author":"De Riva","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2018.09.002_bib14","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.2353\/ajpath.2007.070388","article-title":"Autoimmune dacryoadenitis of NOD\/LtJ mice and its subsequent effects on tear protein composition","volume":"171","author":"Doyle","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.exer.2018.09.002_bib15","doi-asserted-by":"crossref","first-page":"C662","DOI":"10.1152\/ajpcell.00623.2006","article-title":"Direct interaction between Rab3D and the polymeric immunoglobulin receptor and trafficking through regulated secretory vesicles in lacrimal gland acinar cells","volume":"294","author":"Evans","year":"2008","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.exer.2018.09.002_bib16","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1007\/s00018-008-8351-4","article-title":"Regulation of secretory vesicle traffic by Rab small GTPases","volume":"65","author":"Fukuda","year":"2008","journal-title":"Cell. Mol. Life Sci. : CMLS"},{"key":"10.1016\/j.exer.2018.09.002_bib17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10911-005-9586-4","article-title":"Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia","volume":"10","author":"Gudjonsson","year":"2005","journal-title":"J. Mammary Gland Biol. Neoplasia"},{"key":"10.1016\/j.exer.2018.09.002_bib18","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1002\/art.38633","article-title":"Tear cathepsin S as a candidate biomarker for Sjogren's syndrome","volume":"66","author":"Hamm-Alvarez","year":"2014","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.exer.2018.09.002_bib19","first-page":"E607","article-title":"Functional changes in salivary glands of autoimmune disease-prone NOD mice","volume":"263","author":"Hu","year":"1992","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.exer.2018.09.002_bib20","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/08959374960100011501","article-title":"Animal models for autoimmune disease-associated xerostomia and xerophthalmia","volume":"10","author":"Humphreys-Beher","year":"1996","journal-title":"Adv. Dent. Res."},{"key":"10.1016\/j.exer.2018.09.002_bib21","doi-asserted-by":"crossref","first-page":"e43688","DOI":"10.1371\/journal.pone.0043688","article-title":"Accumulation of secretory vesicles in the lacrimal gland epithelia is related to non-Sjogren's type dry eye in visual display terminal users","volume":"7","author":"Kamoi","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2018.09.002_bib22","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0065-2776(08)60490-3","article-title":"The murine autoimmune diabetes model: NOD and related strains","volume":"51","author":"Kikutani","year":"1992","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.exer.2018.09.002_bib23","doi-asserted-by":"crossref","first-page":"G1123","DOI":"10.1152\/ajpgi.00512.2006","article-title":"Mice lacking the transcription factor Mist1 exhibit an altered stress response and increased sensitivity to caerulein-induced pancreatitis","volume":"292","author":"Kowalik","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.exer.2018.09.002_bib24","first-page":"549107","article-title":"Current concepts: mouse models of Sjogren's syndrome","volume":"2011","author":"Lavoie","year":"2011","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.exer.2018.09.002_bib25","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.ajo.2005.06.031","article-title":"Dry eye (Keratoconjunctivitis Sicca), rheumatoid arthritis, and Sjogren's syndrome","volume":"140","author":"Lemp","year":"2005","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.exer.2018.09.002_bib26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0248-4900(96)84782-4","article-title":"Immunolocalization of myoepithelial cells in isolated acini of rat exorbital lacrimal gland: cellular distribution of muscarinic receptors","volume":"86","author":"Lemullois","year":"1996","journal-title":"Biol. Cell."},{"key":"10.1016\/j.exer.2018.09.002_bib27","doi-asserted-by":"crossref","first-page":"5019","DOI":"10.1167\/iovs.09-4523","article-title":"Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse","volume":"51","author":"Li","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.09.002_bib28","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1002\/acr.23173","article-title":"Prevalence of primary Sjogren's syndrome in a US population-based cohort","volume":"69","author":"Maciel","year":"2017","journal-title":"Arthritis Care Res."},{"issue":"Suppl. 3","key":"10.1016\/j.exer.2018.09.002_bib29","first-page":"17","article-title":"The non-obese diabetic (NOD) mouse: an animal model for autoimmune thyroiditis","volume":"104","author":"Many","year":"1996","journal-title":"Exp. Clin. Endocrinol. Diabetes: Offic. J. Ger. Soc. Endocrinol. Ger. Diabetes Assoc."},{"key":"10.1016\/j.exer.2018.09.002_bib30","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1126\/science.1233521","article-title":"Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity","volume":"339","author":"Markle","year":"2013","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.exer.2018.09.002_bib31","doi-asserted-by":"crossref","first-page":"5392","DOI":"10.4049\/jimmunol.1203502","article-title":"Gammadelta T cells are essential effectors of type 1 diabetes in the nonobese diabetic mouse model","volume":"190","author":"Markle","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2018.09.002_bib32","doi-asserted-by":"crossref","first-page":"C942","DOI":"10.1152\/ajpcell.00275.2015","article-title":"Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjogren's Syndrome","volume":"310","author":"Meng","year":"2016","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.exer.2018.09.002_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0184781","article-title":"Interferon-gamma treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjogren's Syndrome","volume":"12","author":"Meng","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2018.09.002_bib34","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.4049\/jimmunol.172.5.2731","article-title":"Of mice and not men: differences between mouse and human immunology","volume":"172","author":"Mestas","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.exer.2018.09.002_bib35","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.fob.2013.01.009","article-title":"Atrophy of myoepithelial cells in parotid glands of diabetic mice; detection using skeletal muscle actin, a novel marker","volume":"3","author":"Nashida","year":"2013","journal-title":"FEBS Open Bio"},{"key":"10.1016\/j.exer.2018.09.002_bib36","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1542-0124(12)70289-6","article-title":"Unraveling the pathophysiology of Sjogren syndrome-associated dry eye disease","volume":"7","author":"Nguyen","year":"2009","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.exer.2018.09.002_bib37","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/bjh.13192","article-title":"Sjogren Syndrome-associated lymphomas: an update on pathogenesis and management","volume":"168","author":"Nocturne","year":"2015","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.exer.2018.09.002_bib38","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.2174\/1381612821666150316120024","article-title":"Mouse models of primary Sjogren's syndrome","volume":"21","author":"Park","year":"2015","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.exer.2018.09.002_bib39","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/(SICI)1097-0185(20000601)259:2<157::AID-AR6>3.0.CO;2-0","article-title":"Mist1 expression is a common link among serous exocrine cells exhibiting regulated exocytosis","volume":"259","author":"Pin","year":"2000","journal-title":"Anat. Rec."},{"key":"10.1016\/j.exer.2018.09.002_bib40","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1073\/pnas.92.9.3849","article-title":"Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages","volume":"92","author":"Reddy","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.exer.2018.09.002_bib41","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1172\/JCI1158","article-title":"Cathepsin S activity regulates antigen presentation and immunity","volume":"101","author":"Riese","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.exer.2018.09.002_bib42","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1601-0825.2011.01852.x","article-title":"Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjogren's syndrome","volume":"18","author":"Roescher","year":"2012","journal-title":"Oral Dis."},{"key":"10.1016\/j.exer.2018.09.002_bib43","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.semarthrit.2013.04.004","article-title":"Malignant lymphoma in primary Sjogren's syndrome: an update on the pathogenesis and treatment","volume":"43","author":"Routsias","year":"2013","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.exer.2018.09.002_bib44","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1172\/JCI0214682","article-title":"Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity","volume":"110","author":"Saegusa","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.exer.2018.09.002_bib45","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1084\/jem.194.5.677","article-title":"Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice","volume":"194","author":"Salomon","year":"2001","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.exer.2018.09.002_bib46","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.exer.2009.10.008","article-title":"Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice exhibiting a Sjogren's syndrome-like exocrinopathy","volume":"90","author":"Schenke-Layland","year":"2010","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2018.09.002_bib47","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jconrel.2013.07.016","article-title":"A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjogren's syndrome","volume":"171","author":"Shah","year":"2013","journal-title":"J. Contr. Release : Offic. J. Contr. Release Soc."},{"key":"10.1016\/j.exer.2018.09.002_bib48","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1167\/iovs.16-19159","article-title":"Rapamycin eye drops suppress lacrimal gland inflammation in a murine model of Sj\u00f6gren's syndrome","volume":"58","author":"Shah","year":"2017","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.09.002_bib49","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1167\/iovs.11-9025","article-title":"Isolation and characterization of progenitor cells in uninjured, adult rat lacrimal gland","volume":"53","author":"Shatos","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.09.002_bib50","first-page":"771","volume":"vol. 5","author":"Simecek","year":"2015"},{"key":"10.1016\/j.exer.2018.09.002_bib51","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10735-017-9751-2","article-title":"Reduced myofilament component in primary Sjogren's syndrome salivary gland myoepithelial cells","volume":"49","author":"Sisto","year":"2018","journal-title":"J. Mol. Histol."},{"key":"10.1016\/j.exer.2018.09.002_bib52","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1046\/j.1365-2249.1997.4691368.x","article-title":"High incidence of autoimmune dacryoadenitis in male non-obese diabetic (NOD) mice depending on sex steroid","volume":"109","author":"Takahashi","year":"1997","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.exer.2018.09.002_bib53","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1128\/MCB.01328-09","article-title":"RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation","volume":"30","author":"Tian","year":"2010","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.exer.2018.09.002_bib54","first-page":"1666","article-title":"Mikulicz's disease and Sjogren's syndrome","volume":"41","author":"Tsubota","year":"2000","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2018.09.002_bib55","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1600-065X.1999.tb01360.x","article-title":"Proteases involved in MHC class II antigen presentation","volume":"172","author":"Villadangos","year":"1999","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.exer.2018.09.002_bib56","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1002\/1529-0131(200007)43:7<1647::AID-ANR31>3.0.CO;2-P","article-title":"Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjogren's syndrome","volume":"43","author":"Waterman","year":"2000","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.exer.2018.09.002_bib57","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.semarthrit.2008.04.002","article-title":"Interferon-gamma is increased in patients with primary Sjogren's syndrome and Raynaud's phenomenon","volume":"39","author":"Willeke","year":"2009","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.exer.2018.09.002_bib58","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.exer.2009.03.020","article-title":"Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland","volume":"89","author":"Wu","year":"2009","journal-title":"Exp. Eye Res."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483518304330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483518304330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T04:59:21Z","timestamp":1757998761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483518304330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":58,"alternative-id":["S0014483518304330"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2018.09.002","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2018.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}