{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T16:09:53Z","timestamp":1773245393220,"version":"3.50.1"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T00:00:00Z","timestamp":1567468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PI16\/00031"],"award-info":[{"award-number":["PI16\/00031"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["PI16\/00380"],"award-info":[{"award-number":["PI16\/00380"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["RD16\/0008\/0026"],"award-info":[{"award-number":["RD16\/0008\/0026"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["SAF2015-67643-P"],"award-info":[{"award-number":["SAF2015-67643-P"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007801","name":"Fundaci\u00f3n S\u00e9neca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.exer.2019.107781","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T19:08:02Z","timestamp":1567105682000},"page":"107781","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["\u03b2-alanine supplementation induces taurine depletion and causes alterations of the retinal nerve fiber layer and axonal transport by retinal ganglion cells"],"prefix":"10.1016","volume":"188","author":[{"given":"Diego","family":"Garc\u00eda-Ayuso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnny","family":"Di Pierdomenico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco J.","family":"Valiente-Soriano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Mart\u00ednez-Vacas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Agudo-Barriuso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Vidal-Sanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serge","family":"Picaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda P.","family":"Villegas-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2019.107781_bib1","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1080\/07315724.2000.10718943","article-title":"Free amino acid content in standard infant formulas: comparison with human milk","volume":"19","author":"Agostoni","year":"2000","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.exer.2019.107781_bib2","first-page":"103","article-title":"Free amino acid content in breast milk of adolescent and adult mothers in Ecuador","volume":"23","author":"Balde\u00f3n","year":"2014","journal-title":"SpringerPlus"},{"key":"10.1016\/j.exer.2019.107781_bib3","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1016\/j.ophtha.2004.03.036","article-title":"Characteristic retinal atrophy with secondary \u201cinverse\u201d optic atrophy identifies vigabatrin toxicity in children","volume":"111","author":"Buncic","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2019.107781_bib4","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1016\/j.ophtha.2012.05.009","article-title":"Patterns of peripapillary retinal nerve fiber layer thinning in vigabatrin-exposed individuals","volume":"119","author":"Clayton","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2019.107781_bib5","first-page":"nmy115","article-title":"A systematic risk assessment and meta-analysis on the use of oral \u03b2-alanine supplementation","author":"Dolan","year":"2019","journal-title":"Adv Nutr. pii"},{"key":"10.1016\/j.exer.2019.107781_bib6","doi-asserted-by":"crossref","first-page":"853","DOI":"10.3109\/02713683.2013.877934","article-title":"Occupational exposure to lead decreases macular, choroidal, and retinal nerve fiber layer thickness in industrial battery workers","volume":"39","author":"Ekinci","year":"2014","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2019.107781_bib7","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1249\/MSS.0b013e31826cdb68","article-title":"Effect of beta-alanine and carnosine supplementation on muscle contractility in mice","volume":"45","author":"Everaert","year":"2013","journal-title":"Med. Sci. Sport. Exerc."},{"key":"10.1016\/j.exer.2019.107781_bib8","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1034\/j.1600-0420.2003.00125.x","article-title":"Characterization of vigabatrin-associated optic atrophy","volume":"81","author":"Fris\u00e9n","year":"2003","journal-title":"Acta Ophthalmol. Scand."},{"key":"10.1016\/j.exer.2019.107781_bib9","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.preteyeres.2014.03.001","article-title":"Taurine: the comeback of a neutraceutical in the prevention of retinal degenerations","volume":"41","author":"Froger","year":"2014","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2019.107781_bib10","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.exer.2010.10.003","article-title":"Retinal ganglion cell numbers and delayed retinal ganglion cell death in the P23H rat retina","volume":"91","author":"Garc\u00eda-Ayuso","year":"2010","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2019.107781_bib11","first-page":"1716","article-title":"Retinal ganglion cell axonal compression by retinal vessels in light-induced retinal degeneration","volume":"17","author":"Garc\u00eda-Ayuso","year":"2011","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2019.107781_bib12","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1136\/bjophthalmol-2013-303958","article-title":"Sectorial loss of retinal ganglion cells in inherited photoreceptor degeneration is due to RGC death","volume":"98","author":"Garc\u00eda-Ayuso","year":"2014","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2019.107781_bib13","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.exer.2017.05.010","article-title":"Light-induced retinal degeneration causes a transient downregulation of melanopsin in the rat retina","volume":"161","author":"Garc\u00eda-Ayuso","year":"2017","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2019.107781_bib14","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1167\/iovs.17-23258","article-title":"Taurine depletion causes ipRGC loss and increases light-induced photoreceptor degeneration","volume":"59","author":"Garc\u00eda-Ayuso","year":"2018","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2019.107781_bib15","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.4103\/1673-5374.239436","article-title":"Retinal remodeling following photoreceptor degeneration causes retinal ganglion cell death","volume":"13","author":"Garcia-Ayuso","year":"2018","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.exer.2019.107781_bib16","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1007\/s00726-012-1273-3","article-title":"Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells","volume":"43","author":"Gaucher","year":"2012","journal-title":"Amino Acids"},{"key":"10.1016\/j.exer.2019.107781_bib17","doi-asserted-by":"crossref","first-page":"4692","DOI":"10.1167\/iovs.16-19535","article-title":"Quantitative and topographical analysis of the losses of cone photoreceptors and retinal ganglion cells under taurine depletion","volume":"57","author":"Hadj-Sa\u00efd","year":"2016","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2019.107781_bib18","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1055\/s-0036-1583183","article-title":"Eye findings on vigabatrin and taurine treatment in two patients with succinic semialdehyde dehydrogenase deficiency","volume":"47","author":"Horvath","year":"2016","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.exer.2019.107781_bib19","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1007\/s00726-016-2292-2","article-title":"The effect of taurine and \u03b2-alanine supplementation on taurine transporter protein and fatigue resistance in skeletal muscle from mdx mice","volume":"48","author":"Horvath","year":"2016","journal-title":"Amino Acids"},{"key":"10.1016\/j.exer.2019.107781_bib20","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/ana.21526","article-title":"Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity","volume":"65","author":"Jammoul","year":"2009","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.exer.2019.107781_bib21","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.mcn.2010.01.008","article-title":"Taurine deficiency damages photoreceptors and retinal ganglion cells in vigabatrin-treated neonatal rats","volume":"43","author":"Jammoul","year":"2010","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.exer.2019.107781_bib22","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-1-4614-6130-2_10","article-title":"Perinatal taurine exposure programs patterns of autonomic nerve activity responses to tooth pulp stimulation in adult male rats","volume":"775","author":"Khimsuksri","year":"2013","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.exer.2019.107781_bib23","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/aos.12030","article-title":"Attenuation of the retinal nerve fibre layer and reduced retinal function assessed by optical coherence tomography and full-field electroretinography in patients exposed to vigabatrin medication","volume":"92","author":"Kjellstr\u00f6m","year":"2014","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.exer.2019.107781_bib24","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/0042-6989(88)90133-2","article-title":"Taurine depletion leads to loss of rat optic nerve axons","volume":"28","author":"Lake","year":"1988","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2019.107781_bib25","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/1028415X.2016.1152004","article-title":"The role of taurine in improving neural stem cells proliferation and differentiation","volume":"20","author":"Li","year":"2017","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.exer.2019.107781_bib26","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1023\/A:1027376511473","article-title":"Taurine and its trophic effects in the retina","volume":"24","author":"Lima","year":"1999","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.exer.2019.107781_bib28","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1212\/01.WNL.0000127773.72699.C8","article-title":"Practice parameter: medical treatment of infantile spasms.","volume":"62","author":"Mackay","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.exer.2019.107781_bib29","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/j.1755-3768.2010.02077.x","article-title":"Retinal nerve fibre layer attenuation: clinical indicator for vigabatrin toxicity","volume":"89","author":"Moseng","year":"2011","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.exer.2019.107781_bib30","doi-asserted-by":"crossref","first-page":"3860","DOI":"10.1167\/iovs.08-3267","article-title":"Brn3a as a marker of retinal ganglion cells: qualitative and quantitative time course studies in naive and optic nerve injured retinas","volume":"50","author":"Nadal-Nicol\u00e1s","year":"2009","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"11","key":"10.1016\/j.exer.2019.107781_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049830","article-title":"Whole number, distribution and co-expression of brn3 transcription factors in retinal ganglion cells of adult albino and pigmented rats","volume":"7","author":"Nadal-Nicol\u00e1s","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2019.107781_bib32","article-title":"Number and distribution of mouse retinal cone photoreceptors: differences between an albino (Swiss) and a pigmented (C57\/BL6) strain","volume":"16","author":"Ort\u00edn-Mart\u00ednez","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2019.107781_bib33","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00726-005-0282-x","article-title":"Decreases in taurine levels induced by beta-alanine treatment did not affect the susceptibility of tissues to lipid peroxidation","volume":"32","author":"Parildar-Karpuzo\u011flu","year":"2007","journal-title":"Amino Acids"},{"key":"10.1016\/j.exer.2019.107781_bib34","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1016\/j.visres.2009.08.020","article-title":"Time-course of the retinal nerve fibre layer degeneration after complete intra-orbital optic nerve transection or crush: a comparative study","volume":"49","author":"Parrilla-Reverter","year":"2009","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2019.107781_bib35","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1111\/j.1528-1167.2010.02657.x","article-title":"Infantile spasms: a U.S. consensus report","volume":"51","author":"Pellock","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.exer.2019.107781_bib36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.clineuro.2017.04.004","article-title":"Reduction of retinal nerve fiber layer thickness in vigabatrin-exposed patients: a meta-analysis","volume":"157","author":"Peng","year":"2017","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.exer.2019.107781_bib37","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.ejps.2015.11.020","article-title":"Interaction of GABA-mimetics with the taurine transporter (TauT, Slc6a6) in hyperosmotic treated Caco-2, LLC-PK1 and rat renal SKPT cells","volume":"82","author":"Rasmussen","year":"2016","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.exer.2019.107781_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0378-3782(78)90048-8","article-title":"Taurine and other free amino acids in milk of man and other mammals","volume":"2","author":"Rassin","year":"1978","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.exer.2019.107781_bib39","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1136\/jnnp.70.6.787","article-title":"Visual field loss associated with vigabatrin: pathological correlations","volume":"70","author":"Ravindran","year":"2001","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.exer.2019.107781_bib40","doi-asserted-by":"crossref","first-page":"4487","DOI":"10.1167\/iovs.15-17145","article-title":"Comparison of retinal nerve fiber layer thinning and retinal ganglion cell loss after optic nerve transection in adult albino rats","volume":"56","author":"Rovere","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2019.107781_bib41","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/978-94-024-1079-2_60","article-title":"Perinatal taurine imbalance followed by high sugar intake alters the effects of estrogen on renal excretory function in adult female rats","volume":"975","author":"Roysommuti","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.exer.2019.107781_bib42","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.visres.2008.09.029","article-title":"A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats","volume":"49","author":"Salinas-Navarro","year":"2009","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2019.107781_bib43","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.exer.2018.02.010","article-title":"Nerve fibre layer degeneration and retinal ganglion cell loss long term after optic nerve crush or transection in adult mice","volume":"170","author":"S\u00e1nchez-Migall\u00f3n","year":"2018","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2019.107781_bib44","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1136\/bjsports-2016-096396","article-title":"\u03b2-alanine supplementation to improve exercise capacity and performance:a systematic review and meta-analysis","volume":"51","author":"Saunders","year":"2017","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.exer.2019.107781_bib45","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1007\/s00417-008-0903-7","article-title":"Axonal transport deficit in the optic nerve of rats with inherited retinitis pigmentosa and experimentally induced glaucoma","volume":"246","author":"Sposato","year":"2008","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2019.107781_bib46","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1159\/000453143","article-title":"The vigabatrin induced retinal toxicity is associated with photopic exposure and taurine deficiency: an in vivo study","volume":"40","author":"Tao","year":"2016","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.exer.2019.107781_bib47","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.neuint.2010.06.001","article-title":"Beta-alanine as a small molecule neurotransmitter","volume":"57","author":"Tiedje","year":"2010","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.exer.2019.107781_bib48","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/978-94-024-1079-2_2","article-title":"Functions of maternally-derived taurine in fetal and neonatal brain development","volume":"975","author":"Tochitani","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.exer.2019.107781_bib49","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s10072-017-2971-0","article-title":"Evaluation of inner retinal layers with optic coherence tomography in vigabatrin-exposed patients","volume":"38","author":"Tu\u011fcu","year":"2017","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.exer.2019.107781_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2011.08.001","article-title":"Understanding glaucomatous damage: anatomical and functional data from ocular hypertensive rodent retinas","volume":"31","author":"Vidal-Sanz","year":"2012","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2019.107781_bib51","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1097\/00001756-199608120-00028","article-title":"Mechanism of retinal ganglion cell loss in inherited retinal dystrophy","volume":"7","author":"Villegas-P\u00e9rez","year":"1996","journal-title":"Neuroreport"},{"key":"10.1016\/j.exer.2019.107781_bib52","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/(SICI)1096-9861(19980302)392:1<58::AID-CNE5>3.0.CO;2-O","article-title":"Ganglion cell loss in RCS rat retina: a result of compression of axons by contracting intraretinal vessels linked to the pigment epithelium","volume":"392","author":"Villegas-P\u00e9rez","year":"1998","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.exer.2019.107781_bib53","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.neuint.2019.02.015","article-title":"Metabolomic analyses of vigabatrin (VGB)-treated mice: GABA-transaminase inhibition significantly alters amino acid profiles in murine neural and non-neural tissues","volume":"125","author":"Walters","year":"2019","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.exer.2019.107781_bib54","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1167\/iovs.05-0854","article-title":"Detecting vigabatrin toxicity by imaging of the retinal nerve fiber layer","volume":"47","author":"Wild","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483519304129?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483519304129?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:29:17Z","timestamp":1762147757000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483519304129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":53,"alternative-id":["S0014483519304129"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2019.107781","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u03b2-alanine supplementation induces taurine depletion and causes alterations of the retinal nerve fiber layer and axonal transport by retinal ganglion cells","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2019.107781","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"107781"}}