{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:52:30Z","timestamp":1777575150151,"version":"3.51.4"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1R43EY029210-01"],"award-info":[{"award-number":["1R43EY029210-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013779","name":"Retina Research Foundation","doi-asserted-by":"publisher","award":["P30 EY010572"],"award-info":[{"award-number":["P30 EY010572"]}],"id":[{"id":"10.13039\/100013779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013779","name":"Retina Research Foundation","doi-asserted-by":"publisher","award":["P30 CA014520"],"award-info":[{"award-number":["P30 CA014520"]}],"id":[{"id":"10.13039\/100013779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013779","name":"Retina Research Foundation","doi-asserted-by":"publisher","award":["R01 EY026078"],"award-info":[{"award-number":["R01 EY026078"]}],"id":[{"id":"10.13039\/100013779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007059","name":"Northwestern University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007059","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006370","name":"Small Business Innovation Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006370","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["P30 EY016665"],"award-info":[{"award-number":["P30 EY016665"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.exer.2020.108030","type":"journal-article","created":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T19:44:09Z","timestamp":1586202249000},"page":"108030","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy"],"prefix":"10.1016","volume":"195","author":[{"given":"Nader","family":"Sheibani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail S.","family":"Zaitoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoujian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soesiawati R.","family":"Darjatmoko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Suscha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-Seok","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine M.","family":"Sorenson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Shifrin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Albert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Melgar-Asensio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irawati","family":"Kandela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"Henkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2020.108030_bib1","first-page":"53878","article-title":"Use of rabbit eyes in pharmacokinetic studies of intraocular drugs","volume":"113","author":"Ahn","year":"2016","journal-title":"J Vis Exp"},{"key":"10.1016\/j.exer.2020.108030_bib2","doi-asserted-by":"crossref","first-page":"614","DOI":"10.2337\/db10-0008","article-title":"Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy. Implications in retinal neovascularization","volume":"60","author":"Al-Shabwarey","year":"2011","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib3","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1167\/iovs.09-4455","article-title":"Effects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularization","volume":"51","author":"Amaral","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"16","key":"10.1016\/j.exer.2020.108030_bib4","doi-asserted-by":"crossref","first-page":"10480","DOI":"10.1074\/jbc.M809259200","article-title":"Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor","volume":"284","author":"Bernard","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"18","key":"10.1016\/j.exer.2020.108030_bib5","doi-asserted-by":"crossref","first-page":"13517","DOI":"10.1074\/jbc.M110.117374","article-title":"Natural angiogenesis inhibitor signals through Erk5 activation of peroxisome proliferator-activated receptor, gamma (PPAR\u03b3)","volume":"285","author":"Biyashev","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.exer.2020.108030_bib6","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1161\/CIRCRESAHA.108.181115","article-title":"Vascular endothelial growth Factor-A specifies formation of native collaterals and regulates collateral growth in ischemia","volume":"103","author":"Clayton","year":"2008","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.exer.2020.108030_bib7","first-page":"219","article-title":"Inhibition of tumor cell, surface ATP synthesis by pigment epithelium-derived factor: implications for antitumor activity","volume":"41","author":"Deshpande","year":"2012","journal-title":"Int. J. Oncol."},{"issue":"1","key":"10.1016\/j.exer.2020.108030_bib8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1006\/mcbr.2000.0191","article-title":"The expression of membrane-associated 67-kDa laminin receptor (67LR) is modulated in vitro by cell-contact inhibition","volume":"3","author":"Donaldson","year":"2000","journal-title":"Mol. Cell Biol. Res. Commun."},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib9","first-page":"821","article-title":"Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth","volume":"43","author":"Duh","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"12","key":"10.1016\/j.exer.2020.108030_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0116423","article-title":"Expression of thrombospondin-1 modulates the angioinflammatory phenotype of choroidal endothelial cells","volume":"9","author":"Fei","year":"2014","journal-title":"PloS One"},{"issue":"12","key":"10.1016\/j.exer.2020.108030_bib11","doi-asserted-by":"crossref","first-page":"5144","DOI":"10.1158\/0008-5472.CAN-04-3744","article-title":"Two functional epitopes of pigment epithelial- derived factor block angiogenesis and induce differentiation in prostate cancer","volume":"65","author":"Filleur","year":"2005","journal-title":"Cancer Res"},{"key":"10.1016\/j.exer.2020.108030_bib12","doi-asserted-by":"crossref","first-page":"6371","DOI":"10.1038\/s41598-018-24197-2","article-title":"Mousetap, a novel technique to collect uncontaminated vitreous or aqueous and expand usefulness of mouse models","volume":"8","author":"Fortmann","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.exer.2020.108030_bib13","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0014-5793(01)02110-X","article-title":"Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularization","volume":"489","author":"Gao","year":"2001","journal-title":"FEBS Lett."},{"issue":"1","key":"10.1016\/j.exer.2020.108030_bib14","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0002-9440(10)64374-X","article-title":"Synthetic peptides interacting with the 67-kd laminin receptor can reduce retinal ischemia and inhibit hypoxia-induced retinal neovascularization","volume":"160","author":"Gebarowska","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.exer.2020.108030_bib15","author":"Gundimeda"},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib16","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.survophthal.2016.12.004","article-title":"Advances in understanding and management of retinopathy of prematurity","volume":"62","author":"Hartnett","year":"2017","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.exer.2020.108030_bib17","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1042\/CS20130463","article-title":"PEDF and its roles in physiological and pathological conditions: imp[lications in diabetic and hypoxia-induced angiogenic diseases","volume":"128","author":"He","year":"2015","journal-title":"Clin. Sci."},{"key":"10.1016\/j.exer.2020.108030_bib18","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/ceo.13368","article-title":"Different effects of various anti-angiogenic treatments in an experimental mouse model of retinopathy of prematurity","volume":"47","author":"Heiduschka","year":"2019","journal-title":"Clin. Exp. Ophthalmol."},{"issue":"6","key":"10.1016\/j.exer.2020.108030_bib19","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3109\/02713683.2014.943910","article-title":"Bevacizumab revisited. Its use in different mouse models of ocular pathologies","volume":"40","author":"Hollanders","year":"2015","journal-title":"Curr. Eye Res."},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib20","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.exer.2008.06.003","article-title":"PEDF-deficient mice exhibit an enhanced rate of retinal vascular expansion and are more sensitive to hyperoxia-mediated vessel obliteration","volume":"87","author":"Huang","year":"2008","journal-title":"Exp. Eye Res."},{"issue":"12","key":"10.1016\/j.exer.2020.108030_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0190131","article-title":"Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1,25(OH)2D3","volume":"12","author":"Jamali","year":"2017","journal-title":"PloS One"},{"issue":"8","key":"10.1016\/j.exer.2020.108030_bib22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.2147\/EB.S94447","article-title":"Revisiting the mouse model of retinopathy of prematurity","volume":"2016","author":"Kim","year":"2016","journal-title":"Eye Brain"},{"key":"10.1016\/j.exer.2020.108030_bib23","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1007\/s00417-019-04394-z","article-title":"Type I pig collagen enhances the efficacy of PEDF 34-mer peptidein a mouse model of laser-induced choroidal neovascularization","volume":"257","author":"Kim","year":"2019","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"issue":"2","key":"10.1016\/j.exer.2020.108030_bib24","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1167\/iovs.14-15842","article-title":"Pharmacokinetics of bevacizumab and its effect on serum VEGF and IGF-1 in infants with retinopathy of prematurity","volume":"56","author":"Kong","year":"2015","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"2","key":"10.1016\/j.exer.2020.108030_bib25","first-page":"787","article-title":"67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis","volume":"123","author":"Kumazoe","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"176","key":"10.1016\/j.exer.2020.108030_bib26","first-page":"1","article-title":"Bronchopulmonary dysplasia: crosstalk between PPARg, Wnt\/b-catenin and TGF-b pathways; the potential therapeutic role of PPARg agonists","volume":"7","author":"Lecarpentier","year":"2019","journal-title":"Front Pediatr"},{"issue":"1","key":"10.1016\/j.exer.2020.108030_bib27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s11596-015-1402-9","article-title":"Time-dependent expression of PEDF and VEGF in blood serum and retina of rats with oxygen-induced retinopathy","volume":"35","author":"Lei","year":"2015","journal-title":"Huazhong Univ Sci Technol [Med Sci]"},{"key":"10.1016\/j.exer.2020.108030_bib28","first-page":"91","article-title":"Retinopathy of prematurity: the need for prevention","volume":"8","author":"Liegl","year":"2016","journal-title":"Eye Brain"},{"issue":"4","key":"10.1016\/j.exer.2020.108030_bib29","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.ajpath.2012.12.020","article-title":"Targeting the IRE1a\/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization","volume":"182","author":"Liu","year":"2013","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib30","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s10456-016-9513-x","article-title":"Pigment epithelium-derived factor (PEDF): a novel trophoblast- derived factor limiting feto-placental angiogenesis in late pregnancy","volume":"19","author":"Loegl","year":"2016","journal-title":"Angiogenesis"},{"key":"10.1016\/j.exer.2020.108030_bib31","first-page":"51846","article-title":"A PEDF-derived peptide inhibits retinal neovascular- ization and blocks mobilization of bone marrow-derived endothelial progenitor cells","author":"Longeras","year":"2012","journal-title":"Exp. Diabetes Res."},{"issue":"2","key":"10.1016\/j.exer.2020.108030_bib32","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00417-008-0936-y","article-title":"Are intravitreal bevacizumab and ranibizumab effective in a rat model of choroidal neovascularization?","volume":"247","author":"Lu","year":"2009","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2020.108030_bib33","first-page":"419","article-title":"Vitreous biomarkers in diabetic retinopathy: a systematic review and meta-analysis","volume":"28","author":"McAuley","year":"2014","journal-title":"JDC"},{"issue":"10","key":"10.1016\/j.exer.2020.108030_bib34","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1167\/iovs.18-24087","article-title":"Extended intravitreal rabbit eye residence of nanoparticles conjugated with cationic arginine peptides for intraocular drug delivery: in vivo imaging","volume":"59","author":"Melgar-Asensio","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib35","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jaapos.2014.01.016","article-title":"Risk and clinical course of retinopathy of prematurity in 78 infants of gestational age 22-25 weeks","volume":"18","author":"Miller","year":"2014","journal-title":"J AAPOS"},{"issue":"5","key":"10.1016\/j.exer.2020.108030_bib36","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1158\/1078-0432.CCR-08-2113","article-title":"Short PEDF-derived peptide inhibits angiogenesis and tumor growth","volume":"15","author":"Mirochnik","year":"2009","journal-title":"Clin. Canc. Res."},{"issue":"2","key":"10.1016\/j.exer.2020.108030_bib37","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.ajpath.2010.10.014","article-title":"Overexpression of pigment epithelium\u2013derived factor inhibits retinal inflammation and neovascularization","volume":"178","author":"Park","year":"2011","journal-title":"Am. J. Pathol."},{"issue":"14","key":"10.1016\/j.exer.2020.108030_bib38","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1128\/MCB.01211-10","article-title":"Identification of a novel inhibitor of the canonical Wnt pathway","volume":"31","author":"Park","year":"2011","journal-title":"Mol and Cell Biol"},{"issue":"8","key":"10.1016\/j.exer.2020.108030_bib39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2147\/EB.S94436","article-title":"Retinopathy of prematurity blindness worldwide: phenotypes in the third epidemic","volume":"2016","author":"Quinn","year":"2016","journal-title":"Eye Brain"},{"key":"10.1016\/j.exer.2020.108030_bib40","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1186\/s12974-017-0943-1","article-title":"Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies","volume":"14","author":"Rivera","year":"2017","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.exer.2020.108030_bib42","doi-asserted-by":"crossref","first-page":"107798","DOI":"10.1016\/j.exer.2019.107798","article-title":"Novel anti-angiogenic PEDF-derived peptides mitigate choroidal neovascularization","volume":"188","author":"Sheibani","year":"2019","journal-title":"Exp. Eye Res."},{"issue":"4","key":"10.1016\/j.exer.2020.108030_bib43","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jaapos.2019.02.008","article-title":"Relationship between severe bronchopulmonary dysplasia and severe retinopathy of prematurity in premature newborns","volume":"23","author":"Singh","year":"2019","journal-title":"J AAPOS"},{"issue":"1\u201314","key":"10.1016\/j.exer.2020.108030_bib44","article-title":"A pathogenic relationship of bronchopulmonary dysplasia and retinopathy of prematurity? A review of angiogenic mediators in both diseases","volume":"6","author":"Stark","year":"2018","journal-title":"Front. Pediatr."},{"issue":"5","key":"10.1016\/j.exer.2020.108030_bib45","first-page":"1359","article-title":"Laminin receptor is preferentially expressed by proliferating retinal vessels in a murine model of ischemic retinopathy","volume":"152","author":"Stitt","year":"1998","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.exer.2020.108030_bib46","first-page":"171","article-title":"Isolation and characterization of murine retinal endothelial cells","volume":"9","author":"Su","year":"2003","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2020.108030_bib47","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.bbrc.2017.05.067","article-title":"Identification of vitreous proteins in retinopathy of prematurity","volume":"488","author":"Sugioka","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exer.2020.108030_bib48","doi-asserted-by":"crossref","first-page":"25509","DOI":"10.1038\/srep25509","article-title":"A novel small molecule ameliorates ocular neovascularisation and synergises with anti- VEGF therapy","volume":"6","author":"Sulaiman","year":"2016","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib49","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1167\/iovs.13-13397","article-title":"Effects of anti-VEGF treatment on the recovery of the developing retina following oxygen-induced retinopathy","volume":"55","author":"Tokunaga","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.exer.2020.108030_bib64","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0095443","article-title":"Pigment epithelium-derived factor 34-mer peptide prevents liver fibrosis and hepatic stellate cell activation through down-regulation of the PDGF receptor","volume":"9","author":"Tsai","year":"2014","journal-title":"PLoSOne"},{"issue":"3","key":"10.1016\/j.exer.2020.108030_bib50","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1080\/01902148.2017.1306897","article-title":"Intra- vitreal bevacizumab alters type IV collagenases and exacerbates arrested alveologenesis in the neonatal rat lungs","volume":"43","author":"Valencia","year":"2017","journal-title":"Exp. Lung Res."},{"key":"10.1016\/j.exer.2020.108030_bib51","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.freeradbiomed.2015.11.019","article-title":"Hydrogen peroxide regulates cell adhesion through the redox sensor RPSA","volume":"90","author":"Vilas-Boas","year":"2016","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.exer.2020.108030_bib52","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nm0402-349","article-title":"Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor","volume":"8","author":"Volpert","year":"2002","journal-title":"Nat. Med."},{"issue":"12","key":"10.1016\/j.exer.2020.108030_bib63","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3109\/02713683.2014.990639","article-title":"Pigment epithelium-derived factor regulates glutamine synthetase and L-glutamate\/L-aspartate transporter in retinas with oxygen-induced retinopathy","volume":"40","author":"Wang","year":"2015","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.exer.2020.108030_bib53","doi-asserted-by":"crossref","first-page":"E1378","DOI":"10.1152\/ajpendo.00252.2009","article-title":"Pigment epithelium-derived factor suppresses adipogenesis via inhibition of the MAPK\/ERK pathway in 3T3-L1 preadipocytes","volume":"297","author":"Wang","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.exer.2020.108030_bib54","first-page":"231","article-title":"Endothelial NADPH oxidase mediates vascular endothelial growth factor receptor 2-induced intravitreal neovascularization in a rat model of retinopathy of prematurity","volume":"20","author":"Wang","year":"2014","journal-title":"Mol. Vis."},{"issue":"17","key":"10.1016\/j.exer.2020.108030_bib55","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1089\/ars.2013.5357","article-title":"NADPH oxidase,NOX1, mediates vascular injury in ischemic retinopathy","volume":"20","author":"Wilkinson-Berka","year":"2014","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.exer.2020.108030_bib56","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1136\/bjo.2006.110890","article-title":"Positive association of pigment epithelium-derived factor with total antioxidant capacity in the vitreous fluid of patients with proliferative diabetic retinopathy","volume":"91","author":"Yokoi","year":"2007","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2020.108030_bib62","doi-asserted-by":"crossref","first-page":"9166","DOI":"10.1038\/s41598-018-27525-8","article-title":"Attenuation of retinal vascular development in neonatal mice subjected to hypoxic-ischemic encephalopathy","volume":"8","author":"Zaitoun","year":"2018","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.exer.2020.108030_bib57","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s10495-015-1186-1","article-title":"PEDF and 34-mer inhibit angiogenesis in the heart by inducing tip cells apoptosis via up- regulating PPAR-\u03b3 to increase surface FasL","volume":"21","author":"Zhang","year":"2016","journal-title":"Apoptosis"},{"key":"10.1016\/j.exer.2020.108030_bib58","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.clp.2013.02.001","article-title":"Retinopathy of prematurity-incidence today","volume":"4","author":"Zin","year":"2013","journal-title":"Clin. Perinatol."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483519309029?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483519309029?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:24:19Z","timestamp":1777404259000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483519309029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":60,"alternative-id":["S0014483519309029"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2020.108030","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2020.108030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108030"}}