{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T01:54:24Z","timestamp":1768874064996,"version":"3.49.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30-AG013846"],"award-info":[{"award-number":["P30-AG013846"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007161","name":"Boston University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007161","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007745","name":"Massachusetts Lions Eye Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007745","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.exer.2024.109818","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T12:06:13Z","timestamp":1706875573000},"page":"109818","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["In vivo quasi-elastic light scattering detects molecular changes in the lenses of adolescents with Down syndrome"],"prefix":"10.1016","volume":"241","author":[{"given":"Srikant","family":"Sarangi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Minaeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle M.","family":"Ledoux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6553-0262","authenticated-orcid":false,"given":"Douglas S.","family":"Parsons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliet A.","family":"Moncaster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caitlin A.","family":"Black","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Hollander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yorghos","family":"Tripodis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John I.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G.","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee E.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2024.109818_bib1","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1098\/rstb.2010.0302","article-title":"Biological glass: structural determinants of eye lens transparency","volume":"366","author":"Bassnett","year":"2011","journal-title":"Philos. Trans. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.exer.2024.109818_bib2","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.3109\/02713688709044506","article-title":"Quantitative detection of the molecular changes associated with early cataractogenesis in the living human lens using quasielastic light scattering","volume":"6","author":"Benedek","year":"1987","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1749-6632.1993.tb23035.x","article-title":"Regulation and expression of the Alzheimer\u2019s \u03b2\/A4 amyloid protein precursor in health, disease, and Down\u2019s syndrome","volume":"695","author":"Beyreuther","year":"1993","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.exer.2024.109818_bib4","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/eurpub\/ckl103","article-title":"The four ages of Down syndrome","volume":"17","author":"Bittles","year":"2007","journal-title":"Eur. J. Publ. Health"},{"key":"10.1016\/j.exer.2024.109818_bib5","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.pbiomolbio.2003.11.012","article-title":"Ageing and vision: structure, stability and function of lens crystallins","volume":"86","author":"Bloemendal","year":"2004","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"10.1016\/j.exer.2024.109818_bib6","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0014-4835(89)90094-8","article-title":"Clinical photon correlation spectroscopy evaluation of human diabetic lenses","volume":"49","author":"Bursell","year":"1989","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0039-6257(90)90116-D","article-title":"Down syndrome","volume":"34","author":"Catalano","year":"1990","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109818_bib8","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00726-002-0337-1","article-title":"Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: challenging the gene dosage effect hypothesis (Part II)","volume":"24","author":"Cheon","year":"2003","journal-title":"Amino Acids"},{"key":"10.1016\/j.exer.2024.109818_bib9","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.exer.2003.10.008","article-title":"Order and disorder in the transparent media of the eye","volume":"78","author":"Clark","year":"2004","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib10","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.exer.2012.06.005","article-title":"Electron tomography of fiber cell cytoplasm and dense cores of multilamellar bodies from human age-related nuclear cataracts","volume":"101","author":"Costello","year":"2012","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108564","article-title":"Crystallin gene expression: insights from studies of transcriptional bursting","volume":"207","author":"Cvekl","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib12","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0002-9394(14)72015-X","article-title":"Ocular findings in Down's syndrome","volume":"122","author":"Da Cunha","year":"1996","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109818_bib13","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1001\/archophthalmol.2008.507","article-title":"Clinical detection of precataractous lens protein changes using dynamic light scattering","volume":"126","author":"Datiles","year":"2008","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109818_bib14","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ophtha.2015.10.007","article-title":"Longitudinal study of age-related cataract using dynamic light scattering: loss of \u03b1-crystallin leads to nuclear cataract development","volume":"123","author":"Datiles","year":"2016","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2024.109818_bib15","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1136\/bjophthalmol-2012-302327","article-title":"Prevalence of ocular abnormalities in adults with Down syndrome in Hong Kong","volume":"97","author":"Fong","year":"2013","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109818_bib16","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/S0140-6736(03)12981-9","article-title":"Cytosolic \u03b2-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease","volume":"361","author":"Goldstein","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.exer.2024.109818_bib17","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.jalz.2014.10.007","article-title":"Down syndrome and Alzheimer's disease: common pathways, common goals","volume":"11","author":"Hartley","year":"2015","journal-title":"Alzheimer's Dementia"},{"key":"10.1016\/j.exer.2024.109818_bib18","first-page":"595","article-title":"The relationship of lenticular changes to mongolism","volume":"49","author":"Igersheimer","year":"1951","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"10.1016\/j.exer.2024.109818_bib19","first-page":"808","article-title":"Ocular findings in Down's syndrome","volume":"78","author":"Jaeger","year":"1980","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"10.1016\/j.exer.2024.109818_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043728","article-title":"\u03b4-Catenin is genetically and biologically associated with cortical cataract and future alzheimer-related structural and functional brain changes","volume":"7","author":"Jun","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2024.109818_bib21","doi-asserted-by":"crossref","first-page":"62","DOI":"10.3389\/fneur.2013.00062","article-title":"Alzheimer's disease diagnosis by detecting exogenous fluorescent signal of ligand bound to beta amyloid in the lens of human eye: an exploratory study","volume":"4","author":"Kerbage","year":"2013","journal-title":"Front. Neurol."},{"key":"10.1016\/j.exer.2024.109818_bib22","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1177\/1533317513520214","article-title":"Detection of amyloid \u03b2 signature in the lens and its correlation in the brain to aid in the diagnosis of Alzheimer's disease","volume":"30","author":"Kerbage","year":"2015","journal-title":"Am. J. Alzheimers. Dis. Other Demen."},{"key":"10.1016\/j.exer.2024.109818_bib23","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/sj.eye.6700208","article-title":"Characteristic ocular findings in Asian children with Down syndrome","volume":"16","author":"Kim","year":"2002","journal-title":"Eye"},{"key":"10.1016\/j.exer.2024.109818_bib24","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1006\/nbdi.1996.0003","article-title":"Sequence of deposition of heterogeneous amyloid \u03b2-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation","volume":"3","author":"Lemere","year":"1996","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.exer.2024.109818_bib25","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1006\/exnr.1997.6777","article-title":"Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis","volume":"150","author":"Leverenz","year":"1998","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.exer.2024.109818_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-66642-1","article-title":"In-vivo anterior segment OCT imaging provides unique insight into cerulean blue-dot opacities and cataracts in Down syndrome","volume":"10","author":"Little","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.exer.2024.109818_bib27","doi-asserted-by":"crossref","first-page":"632","DOI":"10.12968\/hmed.2008.69.11.31686","article-title":"The eye and Down's syndrome","volume":"69","author":"Liyanage","year":"2008","journal-title":"Br. J. Hosp. Med."},{"key":"10.1016\/j.exer.2024.109818_bib28","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S1474-4422(10)70112-5","article-title":"Cognitive deficits and associated neurological complications in individuals with Down's syndrome","volume":"9","author":"Lott","year":"2010","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.exer.2024.109818_bib29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/s41582-018-0132-6","article-title":"Dementia in Down syndrome: unique insights for Alzheimer disease research","volume":"15","author":"Lott","year":"2019","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.exer.2024.109818_bib30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.neurobiolaging.2004.08.005","article-title":"Alzheimer disease and Down syndrome: factors in pathogenesis","volume":"26","author":"Lott","year":"2005","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.exer.2024.109818_bib31","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1136\/bjo.33.3.131","article-title":"The eyes in mongolism","volume":"33","author":"Lowe","year":"1949","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109818_bib32","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/bdr2.1589","article-title":"National population-based estimates for major birth defects, 2010\u20132014","volume":"111","author":"Mai","year":"2019","journal-title":"Birth Defects Res"},{"key":"10.1016\/j.exer.2024.109818_bib33","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1365-2559.1988.tb02018.x","article-title":"Alzheimer's disease and Down's syndrome","volume":"13","author":"Mann","year":"1988","journal-title":"Histopathology"},{"key":"10.1016\/j.exer.2024.109818_bib34","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/jir.12074","article-title":"A prospective 14-year longitudinal follow-up of dementia in persons with Down syndrome","volume":"58","author":"McCarron","year":"2014","journal-title":"J. Intellect. Disabil. Res."},{"key":"10.1016\/j.exer.2024.109818_bib35","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1093\/gerona\/glaa121","article-title":"In Vivo quasi-elastic light scattering eye scanner detects molecular aging in humans","volume":"75","author":"Minaeva","year":"2020","journal-title":"Journals Gerontol. - Ser. A, Biol. Sci. Med. Sci."},{"key":"10.1016\/j.exer.2024.109818_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2022.108974","article-title":"Alzheimer's disease amyloid-\u03b2 pathology in the lens of the eye","volume":"221","author":"Moncaster","year":"2022","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0010659","article-title":"Alzheimer\u2019s disease amyloid-\u03b2 links lens and brain pathology in Down syndrome","volume":"5","author":"Moncaster","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.exer.2024.109818_bib38","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev-neuro-061010-113613","article-title":"Amyloid precursor protein processing and Alzheimer's disease","volume":"34","author":"O'Brien","year":"2011","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.exer.2024.109818_bib39","doi-asserted-by":"crossref","first-page":"8266","DOI":"10.1073\/pnas.85.21.8266","article-title":"Mapping of the gene encoding the beta-amyloid precursor protein and its relationship to the Down syndrome region of chromosome 21","volume":"85","author":"Patterson","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.exer.2024.109818_bib40","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1136\/bmj.2.2586.186","article-title":"Notes on twenty-eight cases of Mongolian imbeciles","volume":"2","author":"Pearce","year":"1910","journal-title":"Br. Med. J."},{"key":"10.1016\/j.exer.2024.109818_bib41","series-title":"Dynamic Light Scattering","year":"1985"},{"key":"10.1016\/j.exer.2024.109818_bib42","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/S0140-6736(03)12987-X","article-title":"Down's syndrome","volume":"361","author":"Roizen","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.exer.2024.109818_bib43","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1023\/B:MCBI.0000049373.15558.b8","article-title":"Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone","volume":"267","author":"Santhoshkumar","year":"2004","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.exer.2024.109818_bib44","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.exer.2008.11.029","article-title":"The structure of the cytoplasm of lens fibers as determined by conical tomography","volume":"88","author":"Schietroma","year":"2009","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib45","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.ijbiomac.2021.02.111","article-title":"Amyloid cross-sequence interaction between A\u03b2(1-40) and \u03b1A(66\u201380) in relation to the pathogenesis of cataract","volume":"179","author":"Schimansky","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.exer.2024.109818_bib46","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/pro.2229","article-title":"Evolution of crystallins for a role in the vertebrate eye lens","volume":"22","author":"Slingsby","year":"2013","journal-title":"Protein Sci."},{"key":"10.1016\/j.exer.2024.109818_bib47","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1126\/science.2949367","article-title":"Amyloid \u03b2 protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus","volume":"235","author":"Tanzi","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.exer.2024.109818_bib48","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1038\/331528a0","article-title":"Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease","volume":"331","author":"Tanzi","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.exer.2024.109818_bib49","first-page":"125","article-title":"Measuring the viscosity of whole bovine lens using a fiber optic oxygen sensing system","volume":"20","author":"Thao","year":"2014","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2024.109818_bib50","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1076\/ceyr.16.3.197.15410","article-title":"Quasielastic light scattering study of the living human lens as a function of age","volume":"16","author":"Thurston","year":"1997","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.exer.2024.109818_bib51","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1038\/nrn3983","article-title":"A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome","volume":"16","author":"Wiseman","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.exer.2024.109818_bib52","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1093\/brain\/awy159","article-title":"Trisomy of human chromosome 21 enhances amyloid-\u03b2 deposition independently of an extra copy of APP","volume":"141","author":"Wiseman","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.exer.2024.109818_bib53","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1212\/WNL.35.7.957","article-title":"Alzheimer's disease in Down's syndrome: clinicopathologic studies","volume":"35","author":"Wisniewski","year":"1985","journal-title":"Neurology"},{"key":"10.1016\/j.exer.2024.109818_bib54","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/ana.410170310","article-title":"Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome","volume":"17","author":"Wisniewski","year":"1985","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.exer.2024.109818_bib55","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0887-8994(97)00029-5","article-title":"Ocular abnormalities in Down syndrome: an analysis of 140 Chinese children","volume":"16","author":"Wong","year":"1997","journal-title":"Pediatr. Neurol."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483524000393?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483524000393?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:36:20Z","timestamp":1762148180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483524000393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":55,"alternative-id":["S0014483524000393"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2024.109818","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vivo quasi-elastic light scattering detects molecular changes in the lenses of adolescents with Down syndrome","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2024.109818","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"109818"}}