{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:37:11Z","timestamp":1792640231502,"version":"4.5.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371058"],"award-info":[{"award-number":["82371058"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2020MH172"],"award-info":[{"award-number":["ZR2020MH172"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.exer.2024.109853","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T02:53:00Z","timestamp":1709607180000},"page":"109853","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGF\u03b2 Ameliorates high myopia-induced ocular hypertension"],"prefix":"10.1016","volume":"241","author":[{"given":"Qianwen","family":"Bu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangliang","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganyu","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingshu","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2024.109853_bib1","first-page":"612","article-title":"Aqueous humor TGF-\u03b22 levels in patients with open-angle glaucoma: a meta-analysis","volume":"21","author":"Agarwal","year":"2015","journal-title":"Mol. Vis."},{"key":"10.1016\/j.exer.2024.109853_bib2","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1080\/10520295.2021.1875502","article-title":"Effects of amnion derived mesenchymal stem cells on fibrosis in a 5\/6 nephrectomy model in rats","volume":"96","author":"Akan","year":"2021","journal-title":"Biotech. Histochem. : official publication of the Biological Stain Commission"},{"key":"10.1016\/j.exer.2024.109853_bib3","doi-asserted-by":"crossref","first-page":"e331","DOI":"10.1111\/aos.13983","article-title":"Review of rodent hypertensive glaucoma models","volume":"97","author":"Biswas","year":"2019","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib4","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.ophtha.2021.04.032","article-title":"The risks and benefits of myopia control","volume":"128","author":"Bullimore","year":"2021","journal-title":"Ophthalmology"},{"key":"10.1016\/j.exer.2024.109853_bib5","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/978-1-4939-7407-8_3","article-title":"The microbead occlusion model of ocular hypertension in mice","volume":"1695","author":"Calkins","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.exer.2024.109853_bib6","doi-asserted-by":"crossref","DOI":"10.1177\/15330338211033077","article-title":"EMT participates in the regulation of exosomes secretion and function in esophageal cancer cells","volume":"20","author":"Chen","year":"2021","journal-title":"Technol. Cancer Res. Treat."},{"key":"10.1016\/j.exer.2024.109853_bib7","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1001\/jamaophthalmol.2022.2762","article-title":"Association between myopic refractive error and primary open-angle glaucoma: a 2-sample mendelian randomization study","volume":"140","author":"Choquet","year":"2022","journal-title":"JAMA ophthalmology"},{"key":"10.1016\/j.exer.2024.109853_bib8","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.exer.2012.04.006","article-title":"The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma","volume":"99","author":"Cone","year":"2012","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109853_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/biom13091328","article-title":"Biomarker signature in aqueous humor mirrors lens epithelial cell activation: new biomolecular aspects from cataractogenic myopia","volume":"13","author":"De Piano","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.exer.2024.109853_bib10","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/s41573-020-0070-z","article-title":"Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine","volume":"19","author":"Dey","year":"2020","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.exer.2024.109853_bib11","doi-asserted-by":"crossref","first-page":"8432","DOI":"10.1111\/jcmm.16803","article-title":"SLC39A5 dysfunction impairs extracellular matrix synthesis in high myopia pathogenesis","volume":"25","author":"Dong","year":"2021","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.exer.2024.109853_bib12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature10137","article-title":"Role of YAP\/TAZ in mechanotransduction","volume":"474","author":"Dupont","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.exer.2024.109853_bib13","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1016\/j.jbiomech.2014.03.031","article-title":"Mechanotransduction and fibrosis","volume":"47","author":"Duscher","year":"2014","journal-title":"J. Biomech."},{"key":"10.1016\/j.exer.2024.109853_bib14","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1167\/iovs.17-23037","article-title":"Anterior choroidal thickness increased in primary open-angle glaucoma and primary angle-closure disease eyes evidenced by ultrasound biomicroscopy and SS-oct","volume":"59","author":"Gao","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2024.109853_bib15","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1038\/s41467-020-20851-4","article-title":"Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries","volume":"12","author":"Gharahkhani","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.exer.2024.109853_bib16","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ajo.2021.10.007","article-title":"Degree of myopia and glaucoma risk: a dose-response meta-analysis","volume":"236","author":"Ha","year":"2022","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.712509","article-title":"Mechanical strain regulates myofibroblast differentiation of human scleral fibroblasts by YAP","volume":"12","author":"Hu","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.exer.2024.109853_bib18","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s40662-020-00210-6","article-title":"Advances in myopia research anatomical findings in highly myopic eyes","volume":"7","author":"Jonas","year":"2020","journal-title":"Eye Vision (London, England)"},{"key":"10.1016\/j.exer.2024.109853_bib19","volume":"vol. 10","author":"Karimi","year":"2023"},{"key":"10.1016\/j.exer.2024.109853_bib20","doi-asserted-by":"crossref","first-page":"9854","DOI":"10.1074\/jbc.RA118.002540","article-title":"Transforming growth factor \u03b22 (TGF\u03b22) signaling plays a key role in glucocorticoid-induced ocular hypertension","volume":"293","author":"Kasetti","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exer.2024.109853_bib21","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.exer.2018.03.001","article-title":"Consensus recommendations for trabecular meshwork cell isolation, characterization and culture","volume":"171","author":"Keller","year":"2018","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109853_bib22","doi-asserted-by":"crossref","first-page":"C1013","DOI":"10.1152\/ajpcell.00599.2020","article-title":"TRPV4-Rho signaling drives cytoskeletal and focal adhesion remodeling in trabecular meshwork cells","volume":"320","author":"Lakk","year":"2021","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.exer.2024.109853_bib23","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1111\/jcmm.15129","article-title":"Extracellular vesicle-mediated crosstalk between NPCE cells and TM cells result in modulation of Wnt signalling pathway and ECM remodelling","volume":"24","author":"Lerner","year":"2020","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.exer.2024.109853_bib24","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1167\/tvst.10.9.15","article-title":"Biomechanical effects of deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: a finite element analysis","volume":"10","author":"Li","year":"2021","journal-title":"Transl. Vis. Sci. Technol."},{"key":"10.1016\/j.exer.2024.109853_bib25","article-title":"Extracellular matrix stiffness and TGF\u03b22 regulate YAP\/TAZ activity in human trabecular meshwork cells","volume":"10","author":"Li","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.exer.2024.109853_bib26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1167\/iovs.63.12.15","article-title":"YAP\/TAZ mediate TGF\u03b22-induced Schlemm's canal cell dysfunction","volume":"63","author":"Li","year":"2022","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.exer.2024.109853_bib27","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000526280","article-title":"The anterior segment biometrics in high myopia eyes","volume":"66","author":"Li","year":"2022","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.exer.2024.109853_bib28","article-title":"YAP modulates TGF-\u03b21-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor","volume":"7","author":"Liu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.exer.2024.109853_bib29","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1001\/jamaophthalmol.2021.1610","article-title":"Association of the MYOC p.(Gln368Ter) variant with glaucoma in a Finnish population","volume":"139","author":"Liuska","year":"2021","journal-title":"JAMA Ophthalmology"},{"key":"10.1016\/j.exer.2024.109853_bib30","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.tcb.2021.10.002","article-title":"Mechanical communication in fibrosis progression","volume":"32","author":"Long","year":"2022","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.exer.2024.109853_bib31","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.exer.2005.09.001","article-title":"Axial myopia induced by a monocularly-deprived facemask in Guinea pigs: a non-invasive and effective model","volume":"82","author":"Lu","year":"2006","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109853_bib32","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.exer.2018.03.013","article-title":"Effects of Interleukin-6 on posterior capsular opacification","volume":"172","author":"Ma","year":"2018","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2024.109853_bib33","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/ceo.12158","article-title":"Progress in understanding the association between high myopia and primary open-angle glaucoma","volume":"42","author":"Ma","year":"2014","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/gad.274027.115","article-title":"Mechanisms of Hippo pathway regulation","volume":"30","author":"Meng","year":"2016","journal-title":"Gene Dev."},{"key":"10.1016\/j.exer.2024.109853_bib35","doi-asserted-by":"crossref","first-page":"6482","DOI":"10.1167\/iovs.16-20671","article-title":"Growth differentiation factor-15-induced contractile activity and extracellular matrix production in human trabecular meshwork cells","volume":"57","author":"Muralidharan","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2024.109853_bib36","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.devcel.2015.02.019","article-title":"Distinct polarity cues direct Taz\/Yap and TGF\u03b2 receptor localization to differentially control TGF\u03b2-induced Smad signaling","volume":"32","author":"Narimatsu","year":"2015","journal-title":"Dev. Cell"},{"key":"10.1016\/j.exer.2024.109853_bib37","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3109\/08820538.2014.912339","article-title":"Topographical analysis of non-glaucomatous myopic optic discs using a confocal scanning laser ophthalmoscope (TopSS)","volume":"30","author":"Oh","year":"2015","journal-title":"Semin. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib38","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/0002-9394(66)92551-7","article-title":"High myopia and primary open-angle glaucoma","volume":"62","author":"Podos","year":"1966","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib39","doi-asserted-by":"crossref","first-page":"5858","DOI":"10.1111\/jcmm.17609","article-title":"CXC- receptor 2 promotes extracellular matrix production and attenuates migration in peripapillary human scleral fibroblasts under mechanical strain","volume":"26","author":"Qiu","year":"2022","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.exer.2024.109853_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/adbi.202000051","article-title":"Differential impact of fluid shear stress and YAP\/TAZ on BMP\/TGF-\u03b2 induced osteogenic target genes","volume":"5","author":"Reichenbach","year":"2021","journal-title":"Advanced biology"},{"key":"10.1016\/j.exer.2024.109853_bib41","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1002\/jcp.25305","article-title":"The outflow pathway: a tissue with morphological and functional unity","volume":"231","author":"Sacc\u00e0","year":"2016","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.exer.2024.109853_bib42","doi-asserted-by":"crossref","first-page":"5251","DOI":"10.1167\/iovs.11-7587","article-title":"Role of TGFbeta\/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins","volume":"52","author":"Sethi","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2024.109853_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.874828","article-title":"Multiomics analysis reveals the mechanical stress-dependent changes in trabecular meshwork cytoskeletal-extracellular matrix interactions","volume":"10","author":"Soundararajan","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.exer.2024.109853_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100933","article-title":"Optic nerve head anatomy in myopia and glaucoma, including parapapillary zones alpha, beta, gamma and delta: histology and clinical features","volume":"83","author":"Wang","year":"2021","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2024.109853_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119564","article-title":"ITGA8 positive cells in the conventional outflow tissue exhibit Schlemm's canal endothelial cell properties","volume":"278","author":"Wang","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.exer.2024.109853_bib46","article-title":"High myopia as risk factor for the 10-year incidence of open-angle glaucoma in the Beijing Eye Study","author":"Wang","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib47","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1167\/iovs.06-0296","article-title":"Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma","volume":"48","author":"Wordinger","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2024.109853_bib48","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/aos.12784","article-title":"Primary angle-closure glaucoma: an update","volume":"94","author":"Wright","year":"2016","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.exer.2024.109853_bib49","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1007\/s11427-017-9140-8","article-title":"Mechanism of the reconstruction of aqueous outflow drainage","volume":"61","author":"Xin","year":"2018","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.exer.2024.109853_bib50","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.cell.2013.08.025","article-title":"Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin\/NF2","volume":"154","author":"Yin","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.exer.2024.109853_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2024.101246","article-title":"Optic neuropathy in high myopia: glaucoma or high myopia or both?","author":"Zhang","year":"2024","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2024.109853_bib52","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.52779","article-title":"Piezo1\/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-\u00df-catenin","volume":"9","author":"Zhou","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.exer.2024.109853_bib53","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s12886-020-01377-1","article-title":"Morphologic and biochemical changes in the retina and sclera induced by form deprivation high myopia in Guinea pigs","volume":"20","author":"Zi","year":"2020","journal-title":"BMC Ophthalmol."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483524000745?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483524000745?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T05:26:37Z","timestamp":1758000397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483524000745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":53,"alternative-id":["S0014483524000745"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2024.109853","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGF\u03b2 Ameliorates high myopia-induced ocular hypertension","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2024.109853","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109853"}}