{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:16:14Z","timestamp":1785867374643,"version":"3.56.0"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101148"],"award-info":[{"award-number":["82101148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.exer.2025.110275","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T07:37:42Z","timestamp":1738827462000},"page":"110275","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["N-methyladenosine (m6A) modification regulates HSPA1A and HSPA1B expression in M\u00fcller cells under high glucose stress"],"prefix":"10.1016","volume":"252","author":[{"given":"Hong","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jini","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhan","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongmei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiping","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.exer.2025.110275_bib1","first-page":"3561","article-title":"Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group","volume":"41","author":"Barber","year":"2000","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"9735","key":"10.1016\/j.exer.2025.110275_bib2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0140-6736(09)62124-3","article-title":"Diabetic retinopathy","volume":"376","author":"Cheung","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.exer.2025.110275_bib3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.visres.2017.03.013","article-title":"Muller cells and diabetic retinopathy","volume":"139","author":"Coughlin","year":"2017","journal-title":"Vis. Res."},{"issue":"11","key":"10.1016\/j.exer.2025.110275_bib4","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1167\/iovs.04-1361","article-title":"Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes","volume":"46","author":"Feit-Leichman","year":"2005","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"12","key":"10.1016\/j.exer.2025.110275_bib5","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1007\/s00125-009-1548-8","article-title":"Interphotoreceptor retinoid-binding protein (IRBP) is downregulated at early stages of diabetic retinopathy","volume":"52","author":"Garcia-Ramirez","year":"2009","journal-title":"Diabetologia"},{"issue":"5","key":"10.1016\/j.exer.2025.110275_bib6","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1159\/000055684","article-title":"Heat shock protein 70 expression increased in rabbit muller cells in the ischemia-reperfusion model","volume":"33","author":"Gohdo","year":"2001","journal-title":"Ophthalmic Res."},{"issue":"1","key":"10.1016\/j.exer.2025.110275_bib7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s12192-008-0068-7","article-title":"Guidelines for the nomenclature of the human heat shock proteins","volume":"14","author":"Kampinga","year":"2009","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.exer.2025.110275_bib8","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/106594","article-title":"Animal models of diabetic retinopathy: summary and comparison","volume":"2013","author":"Lai","year":"2013","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.exer.2025.110275_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103857","article-title":"Targeting long noncoding RNA-AQP4-AS1 for the treatment of retinal neurovascular dysfunction in diabetes mellitus","volume":"77","author":"Li","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.exer.2025.110275_bib10","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.preteyeres.2016.03.001","article-title":"Heat shock proteins in the retina: focus on HSP70 and alpha crystallins in ganglion cell survival","volume":"52","author":"Piri","year":"2016","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2025.110275_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2024.109832","article-title":"Long noncoding RNA ZFAS1: a novel anti-apoptotic target in Fuchs endothelial corneal dystrophy","volume":"241","author":"Qiu","year":"2024","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2025.110275_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108107","article-title":"FTO regulates ocular angiogenesis via m(6)A-YTHDF2-dependent mechanism","volume":"197","author":"Shan","year":"2020","journal-title":"Exp. Eye Res."},{"issue":"1","key":"10.1016\/j.exer.2025.110275_bib13","doi-asserted-by":"crossref","first-page":"277","DOI":"10.7150\/thno.63441","article-title":"METTL3-mediated N(6)-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication","volume":"12","author":"Suo","year":"2022","journal-title":"Theranostics"},{"issue":"11","key":"10.1016\/j.exer.2025.110275_bib14","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1016\/j.ophtha.2021.04.027","article-title":"Global prevalence of diabetic retinopathy and projection of burden through 2045: systematic review and meta-analysis","volume":"128","author":"Teo","year":"2021","journal-title":"Ophthalmology"},{"issue":"7481","key":"10.1016\/j.exer.2025.110275_bib15","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nature12730","article-title":"N6-methyladenosine-dependent regulation of messenger RNA stability","volume":"505","author":"Wang","year":"2014","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.exer.2025.110275_bib16","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.cell.2015.05.014","article-title":"N(6)-methyladenosine modulates messenger RNA translation efficiency","volume":"161","author":"Wang","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.exer.2025.110275_bib17","article-title":"Diabetic retinopathy","volume":"2","author":"Wong","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"3","key":"10.1016\/j.exer.2025.110275_bib18","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1210\/jc.2018-00619","article-title":"Glucose is involved in the dynamic regulation of m6A in patients with type 2 diabetes","volume":"104","author":"Yang","year":"2019","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"10","key":"10.1016\/j.exer.2025.110275_bib19","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/j.ymthe.2020.07.022","article-title":"Role of METTL3-dependent N(6)-methyladenosine mRNA modification in the promotion of angiogenesis","volume":"28","author":"Yao","year":"2020","journal-title":"Mol. Ther."},{"issue":"9","key":"10.1016\/j.exer.2025.110275_bib20","article-title":"Plasma proteins and onset of type 2 diabetes and diabetic complications: proteome-wide Mendelian randomization and colocalization analyses","volume":"4","author":"Yuan","year":"2023","journal-title":"Cell. Rep. Med."},{"key":"10.1016\/j.exer.2025.110275_bib21","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jtos.2024.01.013","article-title":"Single-cell RNA sequencing reveals the complex cellular niche of pterygium","volume":"32","author":"Zhang","year":"2024","journal-title":"Ocul. Surf."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483525000466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483525000466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T19:30:09Z","timestamp":1740511809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483525000466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":21,"alternative-id":["S0014483525000466"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2025.110275","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"N6-methyladenosine (m6A) modification regulates HSPA1A and HSPA1B expression in M\u00fcller cells under high glucose stress","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2025.110275","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110275"}}