{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T06:26:53Z","timestamp":1793600813051,"version":"4.5.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32371015"],"award-info":[{"award-number":["32371015"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018634","name":"State Key Laboratory of Ophthalmology","doi-asserted-by":"publisher","award":["303060202400373"],"award-info":[{"award-number":["303060202400373"]}],"id":[{"id":"10.13039\/501100018634","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020771","name":"Natural Science Foundation for Young Scientists of Shanxi Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Science and Technology Program Key Projects","doi-asserted-by":"publisher","award":["SL2024A03J01262"],"award-info":[{"award-number":["SL2024A03J01262"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515012515"],"award-info":[{"award-number":["2022A1515012515"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.exer.2026.110943","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T16:15:55Z","timestamp":1771949755000},"page":"110943","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Comparison of rod photoreceptor outer segment renewal in wild type and Tmem138-deficient mice using AAV-delivered Dendra2-tagged rhodopsin"],"prefix":"10.1016","volume":"267","author":[{"given":"Lijing","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianlei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchun","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujuan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Ju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiansen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunqiao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exer.2026.110943_bib1","doi-asserted-by":"crossref","first-page":"12651","DOI":"10.1073\/pnas.202320599","article-title":"An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein","volume":"99","author":"Ando","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.preteyeres.2018.12.004","article-title":"Insights into photoreceptor ciliogenesis revealed by animal models","volume":"71","author":"Baehr","year":"2019","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2026.110943_bib3","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1085\/jgp.66.4.407","article-title":"Light-sensitive swelling of isolated frog rod outer segments as an in vitro assay for visual transduction and dark adaptation","volume":"66","author":"Bownds","year":"1975","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.exer.2026.110943_bib4","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.229526","article-title":"The route of the visual receptor rhodopsin along the cilium","volume":"132","author":"Chadha","year":"2019","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.exer.2026.110943_bib5","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.cell.2007.06.030","article-title":"SARA-regulated vesicular targeting underlies formation of the light-sensing organelle in mammalian rods","volume":"130","author":"Chuang","year":"2007","journal-title":"Cell"},{"issue":"553","key":"10.1016\/j.exer.2026.110943_bib6","article-title":"Using photoactivatable fluorescent protein Dendra2 to track protein movement","volume":"42","author":"Chudakov","year":"2007","journal-title":"Biotechniques"},{"key":"10.1016\/j.exer.2026.110943_bib7","doi-asserted-by":"crossref","first-page":"E4400","DOI":"10.1073\/pnas.1510111112","article-title":"Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome","volume":"112","author":"Datta","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib8","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1073\/pnas.0500095102","article-title":"Rhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ADP-ribosylation factor 4 (ARF4)","volume":"102","author":"Deretic","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib9","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1083\/jcb.201508093","article-title":"Discs of mammalian rod photoreceptors form through the membrane evagination mechanism","volume":"211","author":"Ding","year":"2015","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2026.110943_bib10","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/(SICI)1096-9861(19971013)387:1<148::AID-CNE12>3.0.CO;2-Q","article-title":"Evidence from normal and degenerating photoreceptors that two outer segment integral membrane proteins have separate transport pathways","volume":"387","author":"Fariss","year":"1997","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.exer.2026.110943_bib11","doi-asserted-by":"crossref","first-page":"42700","DOI":"10.1074\/jbc.M107511200","article-title":"Folding and subunit assembly of photoreceptor peripherin\/rds is mediated by determinants within the extracellular\/intradiskal EC2 domain: implications for heterogeneous molecular pathologies","volume":"276","author":"Goldberg","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exer.2026.110943_bib12","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/75614","article-title":"Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration","volume":"25","author":"Grimm","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.exer.2026.110943_bib13","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2109934119","article-title":"Tmem138 is localized to the connecting cilium essential for rhodopsin localization and outer segment biogenesis","volume":"119","author":"Guo","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib14","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nbt1191","article-title":"Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light","volume":"24","author":"Gurskaya","year":"2006","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.exer.2026.110943_bib15","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/0042-6989(84)90148-2","article-title":"Two populations of rod photoreceptors in the retina of Xenopus laevis identified with 3H-fucose autoradiography","volume":"24","author":"Hollyfield","year":"1984","journal-title":"Vis. Res."},{"key":"10.1016\/j.exer.2026.110943_bib16","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.devcel.2015.01.027","article-title":"Light regulates the ciliary protein transport and outer segment disc renewal of mammalian photoreceptors","volume":"32","author":"Hsu","year":"2015","journal-title":"Dev. Cell"},{"key":"10.1016\/j.exer.2026.110943_bib17","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0014-5793(03)00368-5","article-title":"An improved rhodopsin\/EGFP fusion protein for use in the generation of transgenic Xenopus laevis","volume":"542","author":"Jin","year":"2003","journal-title":"FEBS Lett."},{"key":"10.1016\/j.exer.2026.110943_bib18","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0014-4835(87)80134-3","article-title":"Lengths of immunolabeled ciliary microtubules in frog photoreceptor outer segments","volume":"44","author":"Kaplan","year":"1987","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.exer.2026.110943_bib19","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1091\/mbc.e10-09-0792","article-title":"IFT20 is required for opsin trafficking and photoreceptor outer segment development","volume":"22","author":"Keady","year":"2011","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.exer.2026.110943_bib20","doi-asserted-by":"crossref","first-page":"3954","DOI":"10.1167\/iovs.07-0257","article-title":"AAV-mediated expression targeting of rod and cone photoreceptors with a human rhodopsin kinase promoter","volume":"48","author":"Khani","year":"2007","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2026.110943_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1167\/iovs.66.11.33","article-title":"Peripherin-2 and ROM1 incorporate directly into the rims of enclosing photoreceptor discs without accumulating in the nascent disc lamellae","volume":"66","author":"Klementieva","year":"2025","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.exer.2026.110943_bib22","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.cell.2007.05.049","article-title":"Taking vesicular transport to the cilium","volume":"129","author":"Leroux","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.exer.2026.110943_bib23","doi-asserted-by":"crossref","first-page":"14176","DOI":"10.1073\/pnas.93.24.14176","article-title":"Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments","volume":"93","author":"Li","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib24","doi-asserted-by":"crossref","first-page":"13621","DOI":"10.1523\/JNEUROSCI.1520-13.2013","article-title":"Signals governing the trafficking and mistrafficking of a ciliary GPCR, rhodopsin","volume":"33","author":"Lodowski","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.exer.2026.110943_bib25","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.1091\/mbc.e03-02-0077","article-title":"The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa","volume":"14","author":"Loewen","year":"2003","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.exer.2026.110943_bib26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/ng.519","article-title":"AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis","volume":"42","author":"Louie","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.exer.2026.110943_bib27","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jphotochem.2014.02.001","article-title":"Steady-state and time-resolved spectroscopic studies of green-to-red photoconversion of fluorescent protein Dendra2","volume":"280","author":"Makarova","year":"2014","journal-title":"J. Photochem. Photobiol. Chem."},{"key":"10.1016\/j.exer.2026.110943_bib28","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0092-8674(00)00023-4","article-title":"Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors","volume":"102","author":"Marszalek","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.exer.2026.110943_bib29","doi-asserted-by":"crossref","first-page":"28242","DOI":"10.1074\/jbc.M101476200","article-title":"A functional rhodopsin-green fluorescent protein fusion protein localizes correctly in transgenic Xenopus laevis retinal rods and is expressed in a time-dependent pattern","volume":"276","author":"Moritz","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exer.2026.110943_bib30","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1146\/annurev.cellbio.042308.113337","article-title":"Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?","volume":"26","author":"Nachury","year":"2010","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.exer.2026.110943_bib31","doi-asserted-by":"crossref","first-page":"4923","DOI":"10.1021\/bi00136a001","article-title":"Rhodopsin: structure, function, and genetics","volume":"31","author":"Nathans","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.exer.2026.110943_bib32","doi-asserted-by":"crossref","first-page":"8164","DOI":"10.1523\/JNEUROSCI.1282-14.2014","article-title":"Submembrane assembly and renewal of rod photoreceptor cGMP-gated channel: insight into the actin-dependent process of outer segment morphogenesis","volume":"34","author":"Nemet","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.exer.2026.110943_bib33","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1039\/c5pp00174a","article-title":"Applications of phototransformable fluorescent proteins for tracking the dynamics of cellular components","volume":"14","author":"Nemet","year":"2015","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.exer.2026.110943_bib34","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1016\/j.bbrc.2017.09.170","article-title":"Fluorescent protein Dendra2 as a ratiometric genetically encoded pH-sensor","volume":"493","author":"Pakhomov","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exer.2026.110943_bib35","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1083\/jcb.200107108","article-title":"The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance","volume":"157","author":"Pazour","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2026.110943_bib36","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.preteyeres.2013.03.002","article-title":"Protein sorting, targeting and trafficking in photoreceptor cells","volume":"36","author":"Pearring","year":"2013","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2026.110943_bib37","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/2046-2530-1-22","article-title":"Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins","volume":"1","author":"Rachel","year":"2012","journal-title":"Cilia"},{"key":"10.1016\/j.exer.2026.110943_bib38","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1093\/hmg\/ddv123","article-title":"CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies","volume":"24","author":"Rachel","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.exer.2026.110943_bib39","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1021\/acs.biochem.5b00003","article-title":"Impact of reduced rhodopsin expression on the structure of rod outer segment disc membranes","volume":"54","author":"Rakshit","year":"2015","journal-title":"Biochemistry"},{"key":"10.1016\/j.exer.2026.110943_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1010154","article-title":"Deletion of CEP164 in mouse photoreceptors post-ciliogenesis interrupts ciliary intraflagellar transport (IFT)","volume":"18","author":"Reed","year":"2022","journal-title":"PLoS Genet."},{"key":"10.1016\/j.exer.2026.110943_bib41","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0507-19.2020","article-title":"RPE cells engulf microvesicles secreted by degenerating rod photoreceptors","volume":"7","author":"Ropelewski","year":"2020","journal-title":"eNeuro"},{"key":"10.1016\/j.exer.2026.110943_bib42","doi-asserted-by":"crossref","first-page":"R75","DOI":"10.1093\/hmg\/ddx163","article-title":"Photoreceptor outer segment as a sink for membrane proteins: hypothesis and implications in retinal ciliopathies","volume":"26","author":"Seo","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.exer.2026.110943_bib43","doi-asserted-by":"crossref","first-page":"5818","DOI":"10.1523\/JNEUROSCI.14-10-05818.1994","article-title":"A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment","volume":"14","author":"Sung","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.exer.2026.110943_bib44","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0092-8674(00)80800-4","article-title":"Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1","volume":"97","author":"Tai","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.exer.2026.110943_bib45","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1091\/mbc.e03-09-0650","article-title":"The C terminus of peripherin\/rds participates in rod outer segment targeting and alignment of disk incisures","volume":"15","author":"Tam","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.exer.2026.110943_bib46","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1523\/JNEUROSCI.3437-13.2014","article-title":"An unconventional secretory pathway mediates the cilia targeting of peripherin\/rds","volume":"34","author":"Tian","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.exer.2026.110943_bib47","doi-asserted-by":"crossref","first-page":"10871","DOI":"10.1073\/pnas.0802278105","article-title":"Monitoring cellular movement in vivo with photoconvertible fluorescence protein \"Kaede\" transgenic mice","volume":"105","author":"Tomura","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib48","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1172\/JCI40926","article-title":"Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice","volume":"120","author":"Tomura","year":"2010","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.exer.2026.110943_bib49","doi-asserted-by":"crossref","first-page":"10587","DOI":"10.1523\/JNEUROSCI.0015-12.2012","article-title":"Live-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2","volume":"32","author":"Trivedi","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.exer.2026.110943_bib50","doi-asserted-by":"crossref","first-page":"14870","DOI":"10.1073\/pnas.1516309112","article-title":"Three-dimensional organization of nascent rod outer segment disk membranes","volume":"112","author":"Volland","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2013.08.004","article-title":"Molecular complexes that direct rhodopsin transport to primary cilia","volume":"38","author":"Wang","year":"2014","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.exer.2026.110943_bib52","doi-asserted-by":"crossref","first-page":"8452","DOI":"10.1073\/pnas.1406593111","article-title":"Characterization and development of photoactivatable fluorescent proteins for single-molecule-based superresolution imaging","volume":"111","author":"Wang","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.exer.2026.110943_bib53","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1083\/jcb.33.1.61","article-title":"The renewal of photoreceptor cell outer segments","volume":"33","author":"Young","year":"1967","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2026.110943_bib54","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1083\/jcb.49.2.303","article-title":"The renewal of rod and cone outer segments in the rhesus monkey","volume":"49","author":"Young","year":"1971","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2026.110943_bib55","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1083\/jcb.42.2.392","article-title":"Participation of the retinal pigment epithelium in the rod outer segment renewal process","volume":"42","author":"Young","year":"1969","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2026.110943_bib56","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1083\/jcb.39.1.169","article-title":"The renewal of protein in retinal rods and cones","volume":"39","author":"Young","year":"1968","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.exer.2026.110943_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0082629","article-title":"An inducible expression system to measure rhodopsin transport in transgenic Xenopus rod outer segments","volume":"8","author":"Zhuo","year":"2013","journal-title":"PLoS One"}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483526000990?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483526000990?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T05:33:23Z","timestamp":1793597603000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483526000990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":57,"alternative-id":["S0014483526000990"],"URL":"https:\/\/doi.org\/10.1016\/j.exer.2026.110943","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of rod photoreceptor outer segment renewal in wild type and Tmem138-deficient mice using AAV-delivered Dendra2-tagged rhodopsin","name":"articletitle","label":"Article Title"},{"value":"Experimental Eye Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exer.2026.110943","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110943"}}