{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T17:41:06Z","timestamp":1773855666137,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Gerontology"],"published-print":{"date-parts":[[2004,8]]},"DOI":"10.1016\/j.exger.2004.06.003","type":"journal-article","created":{"date-parts":[[2004,7,6]],"date-time":"2004-07-06T14:21:04Z","timestamp":1089123664000},"page":"1253-1258","source":"Crossref","is-referenced-by-count":33,"title":["Age-dependent modifications of expression level of VEGF and its receptors in the inner ear"],"prefix":"10.1016","volume":"39","author":[{"given":"Pasqualina","family":"Picciotti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Torsello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"I. Wolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Paludetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonora","family":"Gaetani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Pola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exger.2004.06.003_BIB1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1080\/000164801300366598","article-title":"Laser Doppler measurement of cochlear blood flow changes during conditioning noise exposure","volume":"121","author":"Attanasio","year":"2001","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.exger.2004.06.003_BIB2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1006\/scdb.2001.0290","article-title":"Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders","volume":"13","author":"Carmeliet","year":"2002","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.exger.2004.06.003_BIB3","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1080\/00016480310001501","article-title":"Expression of vascular endothelial growth factor receptors in experimental otitis media in the rat","volume":"123","author":"Chae","year":"2003","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.exger.2004.06.003_BIB4","doi-asserted-by":"crossref","first-page":"322","DOI":"10.3109\/00206090109073129","article-title":"Age related histopatological changes of the stria vascularis: an experimental model","volume":"40","author":"Di Girolamo","year":"2001","journal-title":"Audiology"},{"key":"10.1016\/j.exger.2004.06.003_BIB5","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.jacc.2003.09.016","article-title":"Aging of progenitor cells: limitation for regenerative capacities?","volume":"42","author":"Dimmeler","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.exger.2004.06.003_BIB6","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1210\/edrv-13-1-18","article-title":"Molecular and biological properties of the vascular endothelial growth factor family of proteins","volume":"13","author":"Ferrara","year":"1992","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.exger.2004.06.003_BIB7","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1161\/01.CIR.0000050652.47145.4C","article-title":"Age-dependent impairment of reendothelialization after arterial injury: role of vascular endothelial growth factor","volume":"107","author":"Gennaro","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.exger.2004.06.003_BIB8","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3109\/00206098009070071","article-title":"Genotypic differences in behavioural, physiological and anatomical expression of age-related hearing loss on the laboratory mouse","volume":"19","author":"Henry","year":"1980","journal-title":"Audiology"},{"key":"10.1016\/j.exger.2004.06.003_BIB9","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0304-3940(00)00774-6","article-title":"Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF-receptors Flt-1 and KDR\/Flk-1 in the vestibule of guinea pigs","volume":"280","author":"Hess","year":"2000","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.exger.2004.06.003_BIB10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0378-5955(87)90137-7","article-title":"Aging and the auditory brainstem response in mice with severe or minimal presbyacusis","volume":"30","author":"Hunter","year":"1987","journal-title":"Hear. Res."},{"key":"10.1016\/j.exger.2004.06.003_BIB11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0378-5955(97)00155-X","article-title":"A major gene affecting age-related hearing loss in C57BL\/6J mice","volume":"114","author":"Johnson","year":"1997","journal-title":"Hear. Res."},{"key":"10.1016\/j.exger.2004.06.003_BIB12","doi-asserted-by":"crossref","first-page":"827","DOI":"10.3109\/00016489109138418","article-title":"Age-related degeneration and loss of auditory sensitivity in two mouse genotypes","volume":"11","author":"Li","year":"1991","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.exger.2004.06.003_BIB13","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0378-5955(97)00099-3","article-title":"Age-related decline of auditory function in the chinchilla (Chinchilla laniger)","volume":"111","author":"McFadden","year":"1997","journal-title":"Hear. Res."},{"key":"10.1016\/j.exger.2004.06.003_BIB14","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0378-5955(01)00262-3","article-title":"Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR\/Flk-1 in the cochlea of guinea pigs","volume":"155","author":"Michel","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.exger.2004.06.003_BIB15","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/ijc.10094","article-title":"Regulation of cell cycle progression and apoptosis by beta-carotene in undifferentiated and differentiated HL-60 leukemia cells: possible involvement of a redox mechanism","volume":"97","author":"Palozza","year":"2002","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.exger.2004.06.003_BIB16","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1001\/archotol.1990.01870080054015","article-title":"Cochlear microcirculation in young and old gerbils","volume":"116","author":"Prazma","year":"1990","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.exger.2004.06.003_BIB17","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1161\/01.CIR.99.1.111","article-title":"Age-dependent impairment of angiogenesis","volume":"5","author":"Rivard","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.exger.2004.06.003_BIB18","doi-asserted-by":"crossref","first-page":"29643","DOI":"10.1074\/jbc.M001029200","article-title":"Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity","volume":"275","author":"Rivard","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exger.2004.06.003_BIB19","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1177\/002215540305100902","article-title":"Impaired angiogenesis in aging is associated with alterations in vessel density, matrix composition, inflammatory response, and growth factor expression","volume":"51","author":"Sadoun","year":"2003","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.exger.2004.06.003_BIB20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0378-5955(97)00080-4","article-title":"Age-related thickening of basement membrane in stria vascularis capillaries","volume":"111","author":"Thomopoulos","year":"1997","journal-title":"Hear. Res."}],"container-title":["Experimental Gerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556504001901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556504001901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,6]],"date-time":"2019-02-06T01:55:38Z","timestamp":1549418138000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0531556504001901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S0531556504001901"],"URL":"https:\/\/doi.org\/10.1016\/j.exger.2004.06.003","relation":{},"ISSN":["0531-5565"],"issn-type":[{"value":"0531-5565","type":"print"}],"subject":[],"published":{"date-parts":[[2004,8]]}}}