{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:11:16Z","timestamp":1791274276167,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Gerontology"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.exger.2012.04.010","type":"journal-article","created":{"date-parts":[[2012,5,11]],"date-time":"2012-05-11T12:05:18Z","timestamp":1336737918000},"page":"552-564","source":"Crossref","is-referenced-by-count":106,"title":["Anhedonic-like traits and lack of affective deficits in 18-month-old C57BL\/6 mice: Implications for modeling elderly depression"],"prefix":"10.1016","volume":"47","author":[{"given":"Ewa","family":"Malatynska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry W.M.","family":"Steinbusch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Redkozubova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexei","family":"Bolkunov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aslan","family":"Kubatiev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naira B.","family":"Yeritsyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Vignisse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergei","family":"Bachurin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatyana","family":"Strekalova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exger.2012.04.010_bb0005","series-title":"American Psychiatric Association, Diagnostic and Statistical Manual for Mental Disorders","author":"American Psychiatric Association","year":"2000"},{"key":"10.1016\/j.exger.2012.04.010_bb0010","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/med.10026","article-title":"Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease","volume":"23","author":"Bachurin","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.exger.2012.04.010_bb0015","author":"Bachurin","year":"2008","journal-title":"A drug demonstrating anxiolytic effect based on hydrogenated pyrido (4,3-B) indoles, its pharmacological compound and application method WO2009005771 (A1)"},{"key":"10.1016\/j.exger.2012.04.010_bb0020","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1749-6632.2001.tb03654.x","article-title":"Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer","volume":"939","author":"Bachurin","year":"2001","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.exger.2012.04.010_bb0025","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1749-6632.2003.tb07541.x","article-title":"Mitochondria as a target for neurotoxins and neuroprotective agents","volume":"993","author":"Bachurin","year":"2003","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.exger.2012.04.010_bb0030","first-page":"A 385","article-title":"Dimebon induces neurite outgrowth from hippocampal, spinal, and cortical neurons","volume":"72","author":"Bernales","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.exger.2012.04.010_bb0035","first-page":"R1494","article-title":"Meal patterns associated with the age-related decline in food intake in the Fischer 344 rat","volume":"275","author":"Blanton","year":"1998","journal-title":"Am. J. Physiol."},{"issue":"S1","key":"10.1016\/j.exger.2012.04.010_bb0040","first-page":"50","article-title":"Aging-related anhedonia in C 57 mice and effects of dimebone","volume":"110","author":"Bolkunov","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/j.exger.2012.04.010_bb0045","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0278-5846(98)00009-8","article-title":"Evaluation of efficacies of different classes of antidepressants in the forced swimming test in mice at different ages","volume":"22","author":"Bourin","year":"1998","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0050","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.brainres.2006.07.047","article-title":"Aged rats: sex differences and responses to chronic stress","volume":"1126","author":"Bowman","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0055","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0031-9384(99)00225-5","article-title":"Cocaine and morphine-induced place conditioning in adolescent and adult rats","volume":"68","author":"Campbell","year":"2000","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0060","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.neubiorev.2005.03.008","article-title":"Assessing substrates underlying the behavioural effects of antidepressants using the modified rat forced swimming test","volume":"29","author":"Cryan","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.exger.2012.04.010_bb0065","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.neubiorev.2005.03.009","article-title":"The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice","volume":"29","author":"Cryan","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.exger.2012.04.010_bb0070","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s002130000588","article-title":"Comparison of antidepressant activity in 4- and 40-week-old male mice in the forced swimming test: involvement of 5-HT1A and 5-HT1B receptors in old mice","volume":"153","author":"David","year":"2001","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.exger.2012.04.010_bb0075","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0140-6736(08)61074-0","article-title":"Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled study","volume":"372","author":"Doody","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.exger.2012.04.010_bb0080","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.expneurol.2010.01.017","article-title":"CB1 receptor deficiency decreases wheel-running activity: consequences on emotional behaviours and hippocampal neurogenesis","volume":"224","author":"Dubreucq","year":"2010","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.exger.2012.04.010_bb0085","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.bbr.2004.04.020","article-title":"Susceptibility to subchronic unpredictable stress is related to individual reactivity to threat stimuli in mice","volume":"155","author":"Ducottet","year":"2004","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0090","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.bbr.2009.07.001","article-title":"Influence of light at night on murine anxiety- and depressive-like responses","volume":"205","author":"Fonken","year":"2009","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0095","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.physbeh.2009.02.022","article-title":"Depression-like behaviour of aged male and female mice is ameliorated with administration of testosterone or its metabolites","volume":"97","author":"Frye","year":"2009","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0100","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/geronj\/49.6.P251","article-title":"Age differences in the symptoms of depression: a latent trait analysis","volume":"49","author":"Gallo","year":"1994","journal-title":"J. Gerontol."},{"key":"10.1016\/j.exger.2012.04.010_bb0105","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1111\/j.1532-5415.1997.tb03089.x","article-title":"Depression without sadness: functional outcomes of nondysphoric depression in later life","volume":"45","author":"Gallo","year":"1997","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.exger.2012.04.010_bb0110","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00210-004-0939-0","article-title":"Antidepressant-like effects of the nociceptin\/orphanin FQ receptor antagonist UFP-101: new evidence from rats and mice","volume":"369","author":"Gavioli","year":"2004","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0115","first-page":"1","article-title":"Age- and gender-specific prevalence and risk factors for depressive symptoms in the elderly: a population-based study","volume":"17","author":"Glaesmer","year":"2011","journal-title":"Int. Psychogeriatr."},{"key":"10.1016\/j.exger.2012.04.010_bb0120","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1038\/sj.npp.1301649","article-title":"Aging exacerbates depressive-like behaviour in mice in response to activation of the peripheral innate immune system","volume":"33","author":"Godbout","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.exger.2012.04.010_bb0125","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3109\/10253890.2011.562939","article-title":"Individual differences in chronically defeated male mice: Behavioural, endocrine, immune, and neurotrophic changes as markers of vulnerability to the effects of stress","volume":"15","author":"G\u00f3mez-L\u00e1zaro","year":"2011","journal-title":"Stress"},{"key":"10.1016\/j.exger.2012.04.010_bb0130","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.bbr.2005.06.040","article-title":"Age-related deficits in the retention of memories for cued fear conditioning are reversed by galantamine treatment","volume":"165","author":"Gould","year":"2005","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0135","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","article-title":"Development of a rating scale for primary depressive illness","volume":"6","author":"Hamilton","year":"1967","journal-title":"Br. J. Soc. Clin. Psychol."},{"key":"10.1016\/j.exger.2012.04.010_bb0140","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.lfs.2010.12.016","article-title":"Automated experimental system capturing three behavioural components during murine forced swim test","volume":"88","author":"Hayashi","year":"2011","journal-title":"Life Sci."},{"key":"10.1016\/j.exger.2012.04.010_bb0145","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/j.pnpbp.2008.07.020","article-title":"Aging increases the susceptibility to develop anhedonia in male rats","volume":"32","author":"Herrera-P\u00e9rez","year":"2008","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0150","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ejphar.2010.01.022","article-title":"Aging impairs the antidepressant-like response to citalopram in male rats","volume":"633","author":"Herrera-P\u00e9rez","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0155","first-page":"99","article-title":"Complex response competition and dopamine blocking: choosing of high cost sucrose solution versus low cost water in rats","volume":"38","author":"Hsiao","year":"1995","journal-title":"Chin. J. Physiol."},{"key":"10.1016\/j.exger.2012.04.010_bb0160","article-title":"Age differences in symptom expression in patients with major depression","author":"Hybels","year":"2011","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0165","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.bbr.2009.03.040","article-title":"Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress","volume":"202","author":"Ibarguen-Vargas","year":"2009","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0170","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.euroneuro.2010.06.015","article-title":"Brain responses to chronic social defeat stress: effects on regional oxidative metabolism as a function of a hedonic trait, and gene expression in susceptible and resilient rats","volume":"21","author":"Kanarik","year":"2011","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0175","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1001\/archpsyc.1974.01760160005001","article-title":"Endogenomorphic depression. A conceptual and terminological revision","volume":"31","author":"Klein","year":"1974","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0180","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/geronb\/51B.6.P309","article-title":"Affective states in normal and depressed older people","volume":"51","author":"Lawton","year":"1996","journal-title":"J. Gerontol. B Psychol. Sci. Soc. Sci."},{"key":"10.1016\/j.exger.2012.04.010_bb0185","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/BF02434871","article-title":"Dimebon improves learning in animals with experimental Alzheimer's disease","volume":"129","author":"Lermontova","year":"2000","journal-title":"Bull. Exp. Biol. Med."},{"key":"10.1016\/j.exger.2012.04.010_bb0190","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.physbeh.2006.06.004","article-title":"Involvement of central H1 and H2 receptors in water intake induced by hyperosmolarity, hypovolemia and central cholinergic stimulation","volume":"89","author":"Magrani","year":"2006","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0195","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s00232-001-0169-z","article-title":"Tyramine and monoamine oxidase inhibitors as modulators of the mitochondrial membrane permeability transition","volume":"188","author":"Marcocci","year":"2002","journal-title":"J. Membr. Biol."},{"key":"10.1016\/j.exger.2012.04.010_bb0200","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/hipo.20701","article-title":"Expression of the snoRNA host gene gas5 in the hippocampus is upregulated by age and psychogenic stress and correlates with reduced novelty-induced behaviour in C57BL\/6 mice","volume":"20","author":"Meier","year":"2010","journal-title":"Hippocampus"},{"key":"10.1016\/j.exger.2012.04.010_bb0205","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bbr.2006.07.029","article-title":"Effects of unpredictable chronic mild stress on anxiety and depression-like behaviour in mice","volume":"175","author":"Mineur","year":"2006","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0210","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.physbeh.2010.09.019","article-title":"Emotional behaviour in middle-aged rats: implications for geriatric psychopathologies","volume":"102","author":"Moretti","year":"2011","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0215","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.neulet.2006.03.017","article-title":"Age-related severity of dopaminergic neurodegeneration to MPTP neurotoxicity causes motor dysfunction in C57BL\/6 mice","volume":"401","author":"Ohashi","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.exger.2012.04.010_bb0220","first-page":"1","article-title":"Anxiety and depression in adults in their eighties: do gender differences remain?","volume":"22","author":"Pachana","year":"2011","journal-title":"Int. Psychogeriatr."},{"key":"10.1016\/j.exger.2012.04.010_bb0225","first-page":"8","article-title":"Central administration of insulin-like growth factor-I decreases depressive-like behaviour and brain cytokine expression in mice","volume":"9","author":"Park","year":"2011","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.exger.2012.04.010_bb0230","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1021\/jm8012882","article-title":"Novel isothiourea derivatives as potent neuroprotectors and cognition enhancers: synthesis, biological and physicochemical properties","volume":"52","author":"Perlovich","year":"2009","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.exger.2012.04.010_bb0235","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.cell.2010.06.018","article-title":"Discovery of a proneurogenic, neuroprotective chemical","volume":"142","author":"Pieper","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.exger.2012.04.010_bb0240","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/sj.npp.1301574","article-title":"Stress, depression, and neuroplasticity: a convergence of mechanisms","volume":"33","author":"Pittenger","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.exger.2012.04.010_bb0245","series-title":"Current Protocols in Pharmacology","first-page":"591","article-title":"CNS\u2014psychiatric models of disease: depression","author":"Porsolt","year":"1998"},{"key":"10.1016\/j.exger.2012.04.010_bb0250","first-page":"11","article-title":"Use of the automated tail suspension test for the primary screening of psychotropic agents","volume":"288","author":"Porsolt","year":"1987","journal-title":"Arch. Int. Pharmacodyn. Ther."},{"key":"10.1016\/j.exger.2012.04.010_bb0255","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.bbr.2004.04.008","article-title":"Strain differences in sucrose preference and in the consequences of unpredictable chronic mild stress","volume":"155","author":"Pothion","year":"2004","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0260","article-title":"Neurite outgrowth and mitochondrial function in dimebon treated rat cortical cultures","volume":"6","author":"Protter","year":"2009","journal-title":"Neurodegener Dis"},{"key":"10.1016\/j.exger.2012.04.010_bb0265","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.bbr.2008.11.024","article-title":"The food-conditioned place preference task in adolescent, adult and aged rats of both sexes","volume":"198","author":"Rubinow","year":"2009","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.exger.2012.04.010_bb0270","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.nlm.2006.09.006","article-title":"\u201cDespair\u201d induced by extinction trials in the water maze: relationship with measures of anxiety in aged and adult rats","volume":"87","author":"Schulz","year":"2007","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.exger.2012.04.010_bb0275","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0031-9384(98)00314-X","article-title":"Age-related changes in grooming behaviour and motor activity in female rats","author":"Scimonelli","year":"1999","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0280","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.physbeh.2010.10.001","article-title":"Aging-related changes in the effects of social isolation on social behaviour in rats","volume":"102","author":"Shoji","year":"2011","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0285","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.tips.2009.09.002","article-title":"Glutamate-based antidepressants: 20years on","volume":"30","author":"Skolnick","year":"2009","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.exger.2012.04.010_bb0290","first-page":"842","article-title":"The effect of deprenil on the dopaminergic system of the brain in mice of different genotypes during aging","volume":"44","author":"Skrinskaia","year":"1994","journal-title":"Zh. Vyssh. Nerv. Deiat. Im. I P Pavlova"},{"key":"10.1016\/j.exger.2012.04.010_bb0295","doi-asserted-by":"crossref","DOI":"10.1038\/nature10287","article-title":"Adult hippocampal neurogenesis buffers stress responses and depressive behaviour","author":"Snyder","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.exger.2012.04.010_bb0300","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0278-5846(03)00042-3","article-title":"Prenatal cocaine and\/or nicotine exposure produces depression and anxiety in aging rats","volume":"27","author":"Sobrian","year":"2003","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0305","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/0031-9384(92)90387-H","article-title":"Cognitive and noncognitive processes involved in selective object exploration: comparison between young adult and old rats","volume":"52","author":"Soffi\u00e9","year":"1992","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0310","first-page":"1","article-title":"Increased prevalence of depression in cohorts of the elderly: an 11-year follow-up in the general population\u2014the HUNT study","volume":"18","author":"Solhaug","year":"2011","journal-title":"Int. Psychogeriatr."},{"key":"10.1016\/j.exger.2012.04.010_bb0315","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/dev.20457","article-title":"Sensitivity to ethanol and other hedonic stimuli in an animal model of adolescence: implications for prevention science?","volume":"53","author":"Spear","year":"2010","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.exger.2012.04.010_bb0320","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/BF00428203","article-title":"The tail suspension test: a new method for screening antidepressants in mice","volume":"85","author":"Steru","year":"1985","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.exger.2012.04.010_bb0325","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0278-5846(87)90002-9","article-title":"The automated Tail Suspension Test: a computerized device which differentiates psychotropic drugs","volume":"11","author":"Steru","year":"1987","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0330","first-page":"111","article-title":"Optimization of the chronic stress depression model in C57 BL\/6 mice: evidences for improved validity","volume":"Volume I","author":"Strekalova","year":"2008"},{"key":"10.1016\/j.exger.2012.04.010_bb0335","series-title":"Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioural Tests","first-page":"153","article-title":"Factors of reproducibility of stress-induced anhedonia in chronic stress depression models in mice","author":"Strekalova","year":"2009"},{"key":"10.1016\/j.exger.2012.04.010_bb0340","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.pnpbp.2009.12.014","article-title":"Measuring behaviour with chronic stress depression model in mice","volume":"34","author":"Strekalova","year":"2010","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0345","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1038\/sj.npp.1300532","article-title":"Stressed-induced anhedonia in mice is associated with deficits in forced swimming and exploration","volume":"11","author":"Strekalova","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.exger.2012.04.010_bb0350","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00008877-200505000-00006","article-title":"Stressed-induced hyperlocomotion as a confounding factor in anxiety and depression models in mice","volume":"16","author":"Strekalova","year":"2005","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0355","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00008877-200605000-00008","article-title":"Selective effects of citalopram in the mouse model of stress-induced anhedonia with control effects for chronic stress","volume":"17","author":"Strekalova","year":"2006","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0360","first-page":"728","article-title":"Depressive-like state and sleep in laboratory mice","volume":"58","author":"Strekalova","year":"2008","journal-title":"Zh. Vyssh. Nerv. Deiat. Im. I P Pavlova"},{"key":"10.1016\/j.exger.2012.04.010_bb0365","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1744-9081-7-9","article-title":"Update in the methodology of the chronic stress paradigm: internal control matters","volume":"7","author":"Strekalova","year":"2011","journal-title":"Behav. Brain Funct."},{"key":"10.1016\/j.exger.2012.04.010_bb0370","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.biopsych.2008.02.022","article-title":"Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal","volume":"64","author":"Surget","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0375","author":"Tokarski"},{"issue":"S1","key":"10.1016\/j.exger.2012.04.010_bb0380","first-page":"S61","article-title":"Effects of imipramine on depressive-like behaviour and brain peroxidation in CD1 with a mouse model of stress-induced anhedonia","volume":"20","author":"van Miegem","year":"2009","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0385","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0031-9384(02)00818-1","article-title":"Nicotine-induced conditioned place preference in adolescent and adult rats","volume":"77","author":"Vastola","year":"2002","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.exger.2012.04.010_bb0390","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s002130050475","article-title":"Individual differences in response to imipramine in the mouse tail suspension test","volume":"134","author":"Vaugeois","year":"1997","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.exger.2012.04.010_bb0395","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.pnpbp.2010.12.007","article-title":"Dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice","volume":"35","author":"Vignisse","year":"2011","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.exger.2012.04.010_bb0400","unstructured":"Vignisse, J., Steinbusch, H.W.M., Grigoriev, V., Bettendorf, L., Bolkunov, A., Bachurin, S., Strekalova, T., submitted for publication. Simultaneous and solitary pharmacological manipulation of NMDA- and AMPA-receptors in mice: effects on learning dependent on either glutamate receptor, Neuropharm."},{"key":"10.1016\/j.exger.2012.04.010_bb0405","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000087097","article-title":"Chronic mild stress (CMS) revisited: consistency and behavioural\u2013neurobiological concordance in the effects of CMS","volume":"52","author":"Willner","year":"2005","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.exger.2012.04.010_bb0410","first-page":"1","article-title":"Genetic association between helpless trait and depression-related phenotypes: evidence from crossbreeding studies with H\/Rouen and NH\/Rouen mice","volume":"3","author":"Yacoubi","year":"2011","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.exger.2012.04.010_bb0415","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4140\/TCP.n.2010.93","article-title":"Understanding suicide in the elderly","volume":"25","author":"Zanni","year":"2010","journal-title":"Consult. Pharm."}],"container-title":["Experimental Gerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556512001015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556512001015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T13:19:27Z","timestamp":1713964767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0531556512001015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":83,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0531556512001015"],"URL":"https:\/\/doi.org\/10.1016\/j.exger.2012.04.010","relation":{},"ISSN":["0531-5565"],"issn-type":[{"value":"0531-5565","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}