{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:59:39Z","timestamp":1791946779741,"version":"4.3.4"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"People's Republic of China","award":["201406270102"],"award-info":[{"award-number":["201406270102"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Gerontology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.exger.2017.05.002","type":"journal-article","created":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T19:46:55Z","timestamp":1493927215000},"page":"71-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Acceleration-based training: A new mode of training in senescent rats improving performance and left ventricular and muscle functions"],"prefix":"10.1016","volume":"95","author":[{"given":"Thierry","family":"Launay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iman","family":"Momken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Carreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Mougenot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Long","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanne","family":"De Koning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Niel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Riou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Billat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Besse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exger.2017.05.002_bb0005","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1074\/mcp.O113.034918","article-title":"Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (reverse phase protein array) society","volume":"13","author":"Akbani","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.exger.2017.05.002_bb0010","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1186\/s13063-016-1522-y","article-title":"Effects of a high-intensity interval training program versus a moderate-intensity continuous training program on maximal oxygen uptake and blood pressure in healthy adults: study protocol for a randomized controlled trial","volume":"17","author":"Arboleda Serna","year":"2016","journal-title":"Trials"},{"key":"10.1016\/j.exger.2017.05.002_bb0015","doi-asserted-by":"crossref","first-page":"R381","DOI":"10.1152\/ajpregu.00933.2007","article-title":"AT1 receptor participates in the cardiac hypertrophy induced by resistance training in rats","volume":"295","author":"Barauna","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.exger.2017.05.002_bb0020","doi-asserted-by":"crossref","first-page":"R744","DOI":"10.1152\/ajpregu.90959.2008","article-title":"Exercise training from late middle age until senescence does not attenuate the declines in skeletal muscle aerobic function","volume":"297","author":"Betik","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.exger.2017.05.002_bb0025","article-title":"Case studies in physiology: maximal oxygen consumption and performance in a centenarian cyclist","author":"Billat","year":"2016","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.exger.2017.05.002_bb0030","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/ALN.0000000000000526","article-title":"Overexpression of cyclic adenosine monophosphate effluent protein MRP4 induces an altered response to beta-adrenergic stimulation in the senescent rat heart","volume":"122","author":"Carillion","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.exger.2017.05.002_bb0035","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/ALN.0000000000000011","article-title":"Diaphragmatic function is preserved during severe hemorrhagic shock in the rat","volume":"120","author":"Carreira","year":"2014","journal-title":"Anesthesiology"},{"key":"10.1016\/j.exger.2017.05.002_bb0040","doi-asserted-by":"crossref","first-page":"737","DOI":"10.2165\/00007256-200737090-00001","article-title":"The molecular bases of training adaptation","volume":"37","author":"Coffey","year":"2007","journal-title":"Sports Med."},{"key":"10.1016\/j.exger.2017.05.002_bb0045","doi-asserted-by":"crossref","first-page":"5446","DOI":"10.1002\/pmic.200900209","article-title":"A highly sensitive near-infrared fluorescent detection method to analyze signalling pathways by reverse-phase protein array","volume":"9","author":"Dupuy","year":"2009","journal-title":"Proteomics"},{"key":"10.1016\/j.exger.2017.05.002_bb0050","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s40520-014-0281-4","article-title":"Sarcopenia: a predictor of mortality and the need for early diagnosis and intervention","volume":"27","author":"Filippin","year":"2015","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.exger.2017.05.002_bb0055","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1249\/JES.0000000000000041","article-title":"TGF-beta superfamily signaling in muscle and tendon adaptation to resistance exercise","volume":"43","author":"Gumucio","year":"2015","journal-title":"Exerc. Sport Sci. Rev."},{"key":"10.1016\/j.exger.2017.05.002_bb0060","doi-asserted-by":"crossref","first-page":"877","DOI":"10.2165\/00007256-200333120-00002","article-title":"Rate and mechanism of maximal oxygen consumption decline with aging: implications for exercise training","volume":"33","author":"Hawkins","year":"2003","journal-title":"Sports Med."},{"key":"10.1016\/j.exger.2017.05.002_bb9000","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.0197-3118.2005.04324.x","article-title":"Controlled endurance exercise training and VO2max changes in older adults: a meta-analysis","volume":"8","author":"Huang","year":"2005","journal-title":"Prev. Cardiol."},{"key":"10.1016\/j.exger.2017.05.002_bb0065","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.exger.2016.06.009","article-title":"Novel all-extremity high-intensity interval training improves aerobic fitness, cardiac function and insulin resistance in healthy older adults","volume":"82","author":"Hwang","year":"2016","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.exger.2017.05.002_bb0070","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.exger.2015.11.001","article-title":"Intermittent bout exercise training down-regulates age-associated inflammation in skeletal muscles","volume":"72","author":"Kim","year":"2015","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.exger.2017.05.002_bb0075","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1001\/archinte.161.6.825","article-title":"Cardiovascular fitness as a predictor of mortality in men","volume":"161","author":"Laukkanen","year":"2001","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.exger.2017.05.002_bb0080","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1096\/fasebj.12.11.981","article-title":"Mechanics, energetics, and crossbridge kinetics of rabbit diaphragm during congestive heart failure","volume":"12","author":"Lecarpentier","year":"1998","journal-title":"FASEB J."},{"key":"10.1016\/j.exger.2017.05.002_bb0085","article-title":"A new model of short acceleration-based training improves exercise performance in old mice","author":"Niel","year":"2016","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"10.1016\/j.exger.2017.05.002_bb0090","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/bjc.2015.60","article-title":"ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels","volume":"112","author":"Rondeau","year":"2015","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.exger.2017.05.002_bb0095","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00424-014-1527-x","article-title":"Current understanding of sarcopenia: possible candidates modulating muscle mass","volume":"467","author":"Sakuma","year":"2015","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.exger.2017.05.002_bb0100","doi-asserted-by":"crossref","first-page":"e38686","DOI":"10.1371\/journal.pone.0038686","article-title":"NormaCurve: a SuperCurve-based method that simultaneously quantifies and normalizes reverse phase protein array data","volume":"7","author":"Troncale","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.exger.2017.05.002_bb0105","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/JES.0b013e3181aa65fc","article-title":"High-intensity interval training to maximize cardiac benefits of exercise training?","volume":"37","author":"Wisloff","year":"2009","journal-title":"Exerc. Sport Sci. Rev."},{"key":"10.1016\/j.exger.2017.05.002_bb0110","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s10522-016-9637-9","article-title":"Growing older with health and vitality: a nexus of physical activity, exercise and nutrition","volume":"17","author":"Witard","year":"2016","journal-title":"Biogerontology"}],"container-title":["Experimental Gerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556517300177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556517300177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T11:44:07Z","timestamp":1539258247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0531556517300177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":23,"alternative-id":["S0531556517300177"],"URL":"https:\/\/doi.org\/10.1016\/j.exger.2017.05.002","relation":{},"ISSN":["0531-5565"],"issn-type":[{"value":"0531-5565","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acceleration-based training: A new mode of training in senescent rats improving performance and left ventricular and muscle functions","name":"articletitle","label":"Article Title"},{"value":"Experimental Gerontology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exger.2017.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}