{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:22:20Z","timestamp":1790630540151,"version":"4.1.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Gerontology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.exger.2019.02.017","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T02:27:00Z","timestamp":1551320820000},"page":"40-49","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Orthostatic hypotension and cognition in older adults: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"120","author":[{"given":"Rebecca","family":"Iseli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vi Truc Vo","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sifat","family":"Sharmin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esmee M.","family":"Reijnierse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen Kwang","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea B.","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exger.2019.02.017_bb0005","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1097\/01.hjh.0000467376.80946.1a","article-title":"Evidence for a prognostic role of orthostatic hypertension on survival in a very old institutionalized population","volume":"33","author":"Agnoletti","year":"2015","journal-title":"J. Hypertens."},{"key":"10.1016\/j.exger.2019.02.017_bb0010","doi-asserted-by":"crossref","unstructured":"Agnoletti, D., et al., 1c.02: evidence for a prognostic role of orthostatic hypertension on survival in a very old institutionalized population. J. Hypertens., 2015b. 33 Suppl 1: p. e9.","DOI":"10.1097\/01.hjh.0000467376.80946.1a"},{"issue":"8","key":"10.1016\/j.exger.2019.02.017_bb0015","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/gps.1562","article-title":"Orthostatic hypotension in Parkinson's disease: association with cognitive decline?","volume":"21","author":"Allcock","year":"2006","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0020","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/psyg.12294","article-title":"Cognitive impairment in Parkinson's disease, Alzheimer's dementia, and vascular dementia: the role of the clock-drawing test","volume":"18","author":"Allone","year":"2018","journal-title":"Psychogeriatrics"},{"issue":"6","key":"10.1016\/j.exger.2019.02.017_bb0025","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.amjmed.2008.10.040","article-title":"Hypotension unawareness in profound orthostatic hypotension","volume":"122","author":"Arbogast","year":"2009","journal-title":"Am. J. Med."},{"key":"10.1016\/j.exger.2019.02.017_bb0030","unstructured":"Asensio Lafuente, E., et al., Prevalence of orthostatic hypotension in a series of elderly institutionalized patients. Europace. Conference: EHRA Europace, 2011. 13(no pagination)."},{"key":"10.1016\/j.exger.2019.02.017_bb0035","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2147\/CIA.S129868","article-title":"Which is preferable for orthostatic hypotension diagnosis in older adults: active standing test or head-up tilt table test?","volume":"12","author":"Aydin","year":"2017","journal-title":"Clin. Interv. Aging"},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0040","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1017\/S1041610212001780","article-title":"COST: Cognitive State Test, a brief screening battery for Alzheimer disease in illiterate and literate patients","volume":"25","author":"Babacan-Yildiz","year":"2013","journal-title":"Int. Psychogeriatr."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0045","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s10286-014-0244-z","article-title":"Lack of orthostatic symptoms in dementia patients with orthostatic hypotension","volume":"25","author":"Bengtsson-Lindberg","year":"2015","journal-title":"Clin. Auton. Res."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0050","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.09.002","article-title":"Ultrasound tissue pulsatility imaging suggests impairment in global brain pulsatility and small vessels in elderly patients with orthostatic hypotension","volume":"26","author":"Biogeau","year":"2017","journal-title":"J. Stroke Cerebrovasc. Dis."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0055","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jrsm.12","article-title":"A basic introduction to fixed-effect and random-effects models for meta-analysis","volume":"1","author":"Borenstein","year":"2010","journal-title":"Res. Synth. Methods"},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0060","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ancard.2014.05.013","article-title":"Orthostatic hypotension is associated with more severe hypertension in elderly autonomous diabetic patients from the French Gerodiab study at inclusion","volume":"63","author":"Bouhanick","year":"2014","journal-title":"Ann. Cardiol. Angeiol."},{"key":"10.1016\/j.exger.2019.02.017_bb0065","doi-asserted-by":"crossref","DOI":"10.1519\/JPT.0000000000000186","article-title":"Diminished dynamic physical performance is associated with orthostatic hypotension in geriatric outpatients","author":"de Bruine","year":"2018","journal-title":"J. Geriatr. Phys. Ther."},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0070","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1159\/000081436","article-title":"Mortality and blood pressure in elderly people with and without cognitive impairment","volume":"51","author":"Cacciatore","year":"2005","journal-title":"Gerontology"},{"key":"10.1016\/j.exger.2019.02.017_bb0075","series-title":"Neurology","article-title":"Effects of orthostatic hypotension on cognition in Parkinson disease","author":"Centi","year":"2016"},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0080","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1212\/WNL.0000000000003452","article-title":"Effects of orthostatic hypotension on cognition in Parkinson disease","volume":"88","author":"Centi","year":"2017","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eurger.2011.10.001","article-title":"Is there a risk of orthostatic hypotension associated with antihypertensive therapy in geriatric inpatients?","volume":"3","author":"Coutaz","year":"2012","journal-title":"Eur. Geriatr. Med."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0090","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1161\/HYPERTENSIONAHA.116.07334","article-title":"Orthostatic changes in blood pressure and cognitive status in the elderly: the Progetto Veneto Anziani study","volume":"68","author":"Curreri","year":"2016","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0095","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/practneurol-2016-001520","article-title":"The mini-mental state examination: pitfalls and limitations","volume":"17","author":"Devenney","year":"2017","journal-title":"Pract. Neurol."},{"issue":"11","key":"10.1016\/j.exger.2019.02.017_bb0100","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1212\/WNL.55.11.1621","article-title":"The FAB: a frontal assessment battery at bedside","volume":"55","author":"Dubois","year":"2000","journal-title":"Neurology"},{"issue":"7109","key":"10.1016\/j.exger.2019.02.017_bb0105","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"Bmj"},{"key":"10.1016\/j.exger.2019.02.017_bb0110","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.2147\/CIA.S72316","article-title":"Orthostatic intolerance predicts mild cognitive impairment: incidence of mild cognitive impairment and dementia from the Swedish general population cohort Good Aging in Skane","volume":"9","author":"Elmstahl","year":"2014","journal-title":"Clin. Interv. Aging"},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0115","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s10286-016-0340-3","article-title":"Impaired orthostatic blood pressure recovery and cognitive performance at two-year follow up in older adults: the Irish longitudinal study on ageing.[erratum appears in Clin auton res. 2016 Jun;26(3):243; PMID: 27193801]","volume":"26","author":"Feeney","year":"2016","journal-title":"Clin. Auton. Res."},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0120","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d: a practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0125","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","article-title":"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome","volume":"21","author":"Freeman","year":"2011","journal-title":"Clin. Auton. Res."},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0130","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/jgs.12592","article-title":"Cognitive performance in orthostatic hypotension: findings from a nationally representative sample","volume":"62","author":"Frewen","year":"2014","journal-title":"J. Am. Geriatr. Soc."},{"issue":"10","key":"10.1016\/j.exger.2019.02.017_bb0135","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.amjmed.2007.02.023","article-title":"Orthostatic hypotension in the elderly: diagnosis and treatment","volume":"120","author":"Gupta","year":"2007","journal-title":"Am. J. Med."},{"issue":"4","key":"10.1016\/j.exger.2019.02.017_bb0140","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1093\/ageing\/afx024","article-title":"Is orthostatic hypotension related to falling? A meta-analysis of individual patient data of prospective observational studies","volume":"46","author":"Hartog","year":"2017","journal-title":"Age Ageing"},{"issue":"9","key":"10.1016\/j.exger.2019.02.017_bb0145","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1111\/jgs.13596","article-title":"Orthostatic blood pressure behavior in people with mild cognitive impairment predicts conversion to dementia","volume":"63","author":"Hayakawa","year":"2015","journal-title":"J. Am. Geriatr. Soc."},{"issue":"4","key":"10.1016\/j.exger.2019.02.017_bb0150","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1136\/jnnp.73.4.385","article-title":"Testing cognitive function in elderly populations: the PROSPER study","volume":"73","author":"Houx","year":"2002","journal-title":"PROspective Study of Pravastatin in the Elderly at Risk. J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.exger.2019.02.017_bb0155","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3389\/fneur.2017.00121","article-title":"Orthostatic hypotension predicts cognitive impairment in the elderly: findings from a cohort study","volume":"8","author":"Huang","year":"2017","journal-title":"Front. Neurol."},{"key":"10.1016\/j.exger.2019.02.017_bb0160","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1192\/bjp.140.6.566","article-title":"A new clinical scale for the staging of dementia","volume":"140","author":"Hughes","year":"1982","journal-title":"Br. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0165","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10286-007-0410-7","article-title":"Autonomic and cognitive dysfunction in Parkinson's disease","volume":"17","author":"Idiaquez","year":"2007","journal-title":"Clin. Auton. Res."},{"issue":"5","key":"10.1016\/j.exger.2019.02.017_bb0170","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/BF00294806","article-title":"Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain","volume":"90","author":"Jendroska","year":"1995","journal-title":"Acta Neuropathol."},{"issue":"Suppl. 1","key":"10.1016\/j.exger.2019.02.017_bb0175","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/j.nephro.2017.01.003","article-title":"Orthostatic hypotension: a review","volume":"13","author":"Joseph","year":"2017","journal-title":"Nephrol. Ther."},{"key":"10.1016\/j.exger.2019.02.017_bb0180","doi-asserted-by":"crossref","unstructured":"Joseph, A., et al., Orthostatic hypotension: A review. N\u00e9phrologie & Th\u00e9rapeutique, 2017b. 13, Supplement 1: p. S55-S67.","DOI":"10.1016\/j.nephro.2017.01.003"},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0185","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0735-1097(02)01923-X","article-title":"U-curve relationship between orthostatic blood pressure change and silent cerebrovascular disease in elderly hypertensives: orthostatic hypertension as a new cardiovascular risk factor","volume":"40","author":"Kario","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"issue":"13","key":"10.1016\/j.exger.2019.02.017_bb0190","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1212\/WNL.0b013e31826c1acd","article-title":"Association of cognitive dysfunction with neurocirculatory abnormalities in early Parkinson disease","volume":"79","author":"Kim","year":"2012","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0195","first-page":"282","article-title":"Prevalence of orthostatic hypotension in a series of elderly Mexican institutionalized patients","volume":"18","author":"L","year":"2011","journal-title":"Cardiol. J."},{"issue":"10","key":"10.1016\/j.exger.2019.02.017_bb0200","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jclinepi.2009.06.006","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"62","author":"Liberati","year":"2009","journal-title":"J. Clin. Epidemiol."},{"issue":"9","key":"10.1016\/j.exger.2019.02.017_bb0205","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.jamda.2018.04.018","article-title":"Orthostatic hypotension in the elderly: a marker of clinical frailty?","volume":"19","author":"Liguori","year":"2018","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"10.1016\/j.exger.2019.02.017_bb0210","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1471-2288-14-45","article-title":"Newcastle-Ottawa scale: comparing reviewers' to authors' assessments","volume":"14","author":"Lo","year":"2014","journal-title":"BMC Med. Res. Methodol."},{"issue":"Suppl. 1","key":"10.1016\/j.exger.2019.02.017_bb0215","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s10286-007-1001-3","article-title":"Prevalence of orthostatic hypotension","volume":"18","author":"Low","year":"2008","journal-title":"Clin. Auton. Res."},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0220","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1001\/archinte.159.3.273","article-title":"Prognosis of diastolic and systolic orthostatic hypotension in older persons","volume":"159","author":"Luukinen","year":"1999","journal-title":"Arch. Intern. Med."},{"issue":"11","key":"10.1016\/j.exger.2019.02.017_bb0225","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1161\/01.STR.28.11.2169","article-title":"Postural dysregulation in systolic blood pressure is associated with worsened scoring on neurobehavioral function tests and leukoaraiosis in the older elderly living in a community","volume":"28","author":"Matsubayashi","year":"1997","journal-title":"Stroke"},{"issue":"1\u20132","key":"10.1016\/j.exger.2019.02.017_bb0230","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jns.2010.08.056","article-title":"Relationship between orthostatic hypotension and cognitive impairment in the elderly","volume":"299","author":"Mehrabian","year":"2010","journal-title":"J. Neurol. Sci."},{"issue":"4","key":"10.1016\/j.exger.2019.02.017_bb0235","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jpsychires.2008.04.014","article-title":"A meta-analysis of the accuracy of the mini-mental state examination in the detection of dementia and mild cognitive impairment","volume":"43","author":"Mitchell","year":"2009","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.exger.2019.02.017_bb0240","series-title":"JAMDA","article-title":"Orthostatic hypotension and falls in older adults: A systematic review and meta-analysis","author":"Mol","year":"2018"},{"key":"10.1016\/j.exger.2019.02.017_bb0245","doi-asserted-by":"crossref","unstructured":"Mol, A., et al., Rapid systolic blood pressure changes after standing up associate with impaired physical performance in geriatric outpatients. J. Am. Heart Assoc., 2018b. 7(21): p. e010060.","DOI":"10.1161\/JAHA.118.010060"},{"key":"10.1016\/j.exger.2019.02.017_bb0250","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.arr.2018.10.007","article-title":"Orthostatic hypotension and physical functioning in older adults: a systematic review and meta-analysis","volume":"48","author":"Mol","year":"2018","journal-title":"Ageing Res. Rev."},{"issue":"12","key":"10.1016\/j.exger.2019.02.017_bb0255","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/nrcardio.2010.161","article-title":"The relationship between blood pressure and cognitive function","volume":"7","author":"Novak","year":"2010","journal-title":"Nat. Rev. Cardiol."},{"issue":"4","key":"10.1016\/j.exger.2019.02.017_bb0260","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1002\/gps.4485","article-title":"Sub-clinical orthostatic hypotension is associated with greater subjective memory impairment in older adults","volume":"32","author":"O'Hare","year":"2017","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"4","key":"10.1016\/j.exger.2019.02.017_bb0265","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.3233\/JAD-161228","article-title":"Cognitive status, gray matter atrophy, and lower orthostatic blood pressure in older adults","volume":"57","author":"O'Hare","year":"2017","journal-title":"J. Alzheimers Dis."},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0270","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/jgs.12721","article-title":"Comprehensive geriatric assessment reveals sleep disturbances in community-dwelling elderly adults associated with even slight cognitive decline","volume":"62","author":"Otsuka","year":"2014","journal-title":"J. Am. Geriatr. Soc."},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0275","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF02291403","article-title":"Orthostatic hypotension in organic dementia: relationship between blood pressure, cortical blood flow and symptoms","volume":"6","author":"Passant","year":"1996","journal-title":"Clin. Auton. Res."},{"issue":"5","key":"10.1016\/j.exger.2019.02.017_bb0280","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00702-006-0615-2","article-title":"Orthostatic hypotension and attention in Parkinson's disease with and without dementia","volume":"114","author":"Peralta","year":"2007","journal-title":"J. Neural Transm. (Vienna)"},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0285","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00415-012-6627-y","article-title":"Cognitive and MRI correlates of orthostatic hypotension in Parkinson's disease","volume":"260","author":"Pilleri","year":"2013","journal-title":"J. Neurol."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0290","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s10072-011-0746-6","article-title":"Standing worsens cognitive functions in patients with neurogenic orthostatic hypotension","volume":"33","author":"Poda","year":"2012","journal-title":"Neurol. Sci."},{"issue":"29","key":"10.1016\/j.exger.2019.02.017_bb0295","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000004264","article-title":"The association between orthostatic hypotension and cognitive state among adults 65\u202fyears and older who underwent a comprehensive geriatric assessment","volume":"95","author":"Punchick","year":"2016","journal-title":"Medicine"},{"issue":"25","key":"10.1016\/j.exger.2019.02.017_bb0300","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/eurheartj\/ehv093","article-title":"Cardiovascular morbidity and mortality related to orthostatic hypotension: a meta-analysis of prospective observational studies","volume":"36","author":"Ricci","year":"2015","journal-title":"Eur. Heart J."},{"issue":"6 Pt 1","key":"10.1016\/j.exger.2019.02.017_bb0305","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1161\/01.HYP.19.6.508","article-title":"Orthostatic hypotension in older adults. The cardiovascular health study. CHS collaborative research group","volume":"19","author":"Rutan","year":"1992","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0310","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1177\/1533317512466692","article-title":"Hypotensive syndromes are not associated with cognitive impairment in geriatric patients","volume":"28","author":"Schoon","year":"2013","journal-title":"Am. J. Alzheimers Dis. Other Demen."},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(99)02113-7","article-title":"Hypoperfusion induces overexpression of beta-amyloid precursor protein mRNA in a focal ischemic rodent model","volume":"853","author":"Shi","year":"2000","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0320","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF03399657","article-title":"Orthostatic hypotension in Alzheimer's disease: result or cause of brain dysfunction?","volume":"11","author":"Siennicki-Lantz","year":"1999","journal-title":"Aging Clin. Exp. Res."},{"issue":"2","key":"10.1016\/j.exger.2019.02.017_bb0325","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1159\/000363514","article-title":"Persistence and prognostic implications of orthostatic hypotension in older individuals with mild-to-moderate dementia","volume":"4","author":"Soennesyn","year":"2014","journal-title":"Dement. Geriatr. Cogn. Disord. Extra"},{"issue":"4","key":"10.1016\/j.exger.2019.02.017_bb0330","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000247586","article-title":"High prevalence of orthostatic hypotension in mild dementia","volume":"28","author":"Sonnesyn","year":"2009","journal-title":"Dement. Geriatr. Cogn. Disord."},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0335","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.archger.2014.03.008","article-title":"Does vitamin D deficiency increase orthostatic hypotension risk in the elderly patients?","volume":"59","author":"Soysal","year":"2014","journal-title":"Arch. Gerontol. Geriatr."},{"issue":"1","key":"10.1016\/j.exger.2019.02.017_bb0340","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s10286-015-0324-8","article-title":"Clinical characteristics of supine hypertension in de novo Parkinson disease","volume":"26","author":"Umehara","year":"2016","journal-title":"Clin. Auton. Res."},{"issue":"5","key":"10.1016\/j.exger.2019.02.017_bb0345","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1532-5415.1999.tb02576.x","article-title":"Orthostatic hypotension and cognitive decline in older people","volume":"47","author":"Viramo","year":"1999","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.exger.2019.02.017_bb0350","doi-asserted-by":"crossref","unstructured":"Wolters, F.J., et al., Orthostatic hypotension and the long-term risk of dementia: a population-based study. PLoS Med., 2016a. 13 (10) (no pagination)(e1002143).","DOI":"10.1371\/journal.pmed.1002143"},{"issue":"7 Supplement","key":"10.1016\/j.exger.2019.02.017_bb0355","doi-asserted-by":"crossref","first-page":"P248","DOI":"10.1016\/j.jalz.2016.06.444","article-title":"Orthostatic hypotension and the longterm risk of dementia: a populationbased study","volume":"12","author":"Wolters","year":"2016","journal-title":"Alzheimers Dement."},{"issue":"3","key":"10.1016\/j.exger.2019.02.017_bb0360","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000160955","article-title":"Orthostatic hypotension, hypotension and cognitive status: early comorbid markers of primary dementia?","volume":"26","author":"Yap","year":"2008","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.exger.2019.02.017_bb0365","first-page":"S59","article-title":"Is orthostatic hypotension and hypotension a marker of pre-dementia?","volume":"1","author":"Yap","year":"2014","journal-title":"Ann. Acad. Med. Singap."}],"container-title":["Experimental Gerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556518307678?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556518307678?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T06:51:57Z","timestamp":1574146317000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0531556518307678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":73,"alternative-id":["S0531556518307678"],"URL":"https:\/\/doi.org\/10.1016\/j.exger.2019.02.017","relation":{},"ISSN":["0531-5565"],"issn-type":[{"value":"0531-5565","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Orthostatic hypotension and cognition in older adults: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Experimental Gerontology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exger.2019.02.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}