{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T04:54:43Z","timestamp":1767675283243,"version":"build-2065373602"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973793","82004269","82104784","82174314"],"award-info":[{"award-number":["81973793","82004269","82104784","82174314"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016350","name":"Sichuan Provincial Administration of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["2017333"],"award-info":[{"award-number":["2017333"]}],"id":[{"id":"10.13039\/501100016350","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Gerontology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.exger.2023.112341","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T23:10:07Z","timestamp":1701990607000},"page":"112341","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Experimental models for elderly patients with membranous nephropathy: Application and advancements"],"prefix":"10.1016","volume":"185","author":[{"given":"Xinyue","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoran","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuehong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qihan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanxue","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhendong","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naiqian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongliang","family":"Rui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoli","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.exger.2023.112341_bb0005","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0272-6386(89)80024-1","article-title":"Immune mechanisms in idiopathic membranous nephropathy: the role of the interstitial infiltrates","volume":"13","author":"Alexopoulos","year":"1989","journal-title":"Am. J. Kidney Dis."},{"issue":"40","key":"10.1016\/j.exger.2023.112341_bb0010","doi-asserted-by":"crossref","first-page":"13146","DOI":"10.1021\/bi00040a028","article-title":"Multifunctional activity of the extracellular domain of the M-type (180 kDa) membrane receptor for secretory phospholipases A2","volume":"34","author":"Ancian","year":"1995","journal-title":"Biochemistry"},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0015","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1084\/jem.175.3.623","article-title":"A nephritogenic rat monoclonal antibody to mouse aminopeptidase A. Induction of massive albuminuria after a single intravenous injection","volume":"175","author":"Assmann","year":"1992","journal-title":"J. Exp. Med."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0020","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/embor.2008.255","article-title":"The M-type receptor PLA2R regulates senescence through the p53 pathway","volume":"10","author":"Augert","year":"2009","journal-title":"EMBO Rep."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0025","first-page":"185","article-title":"Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats","volume":"135","author":"Baker","year":"1989","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0030","first-page":"282","article-title":"Induction of an autologous immune complex glomerulonephritis in the rat by intravenous injection of heterologous anti-rat kidney tubular antibody. II. Early glomerular lesions","volume":"55","author":"Barabas","year":"1974","journal-title":"Br. J. Exp. Pathol."},{"issue":"1\u20136","key":"10.1016\/j.exger.2023.112341_bb0035","first-page":"336","article-title":"Anionic binding sites in the glomerular basement membrane: possible role in the pathogenesis of immune complex glomerulonephritis","volume":"3","author":"Batsford","year":"1980","journal-title":"Ren. Physiol."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0040","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa0810457","article-title":"M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy","volume":"361","author":"Beck","year":"2009","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0045","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.mayocp.2020.11.028","article-title":"A target antigen-based approach to the classification of membranous nephropathy","volume":"96","author":"Bobart","year":"2021","journal-title":"Mayo Clin. Proc."},{"issue":"11","key":"10.1016\/j.exger.2023.112341_bb0050","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.1093\/ndt\/gfh419","article-title":"Mouse model of membranous nephropathy induced by cationic bovine serum albumin: antigen dose-response relations and strain differences","volume":"19","author":"Chen","year":"2004","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.exger.2023.112341_bb0055","article-title":"Case report: THSD7A-positive membranous nephropathy caused by tislelizumab in a lung cancer patient","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.exger.2023.112341_bb0060","doi-asserted-by":"crossref","first-page":"983","DOI":"10.2215\/CJN.11761116","article-title":"Primary membranous nephropathy [published correction appears in Clin J Am Soc Nephrol. 2017 Sep 7;12 (9):1528]","volume":"12","author":"Couser","year":"2017","journal-title":"Clin. J. Am. Soc. Nephrol."},{"issue":"4","key":"10.1016\/j.exger.2023.112341_bb0065","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1172\/JCI112408","article-title":"Complement-induced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy","volume":"77","author":"Cybulsky","year":"1986","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.exger.2023.112341_bb0070","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1046\/j.1523-1755.1998.00013.x","article-title":"Complement activates phospholipases and protein kinases in glomerular epithelial cells","volume":"54","author":"Cybulsky","year":"1998","journal-title":"Kidney Int."},{"issue":"26","key":"10.1016\/j.exger.2023.112341_bb0075","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1056\/NEJMoa012895","article-title":"Antenatal membranous glomerulonephritis due to anti-neutral endopeptidase antibodies","volume":"346","author":"Debiec","year":"2002","journal-title":"N. Engl. J. Med."},{"issue":"22","key":"10.1016\/j.exger.2023.112341_bb0080","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1056\/NEJMoa1013792","article-title":"Early-childhood membranous nephropathy due to cationic bovine serum albumin [published correction appears in N Engl J Med. 2011 Aug 4;365(5):477] [published correction appears in N Engl J Med. 2014 Feb 27;370(9):886]","volume":"364","author":"Debiec","year":"2011","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.exger.2023.112341_bb0085","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1681\/ASN.2021101384","article-title":"Complement C3a and C3a receptor activation mediates podocyte injuries in the mechanism of primary membranous nephropathy","volume":"33","author":"Gao","year":"2022","journal-title":"J. Am. Soc. Nephrol."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0090","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1053\/j.ajkd.2010.01.008","article-title":"The pathogenesis of idiopathic membranous nephropathy: a 50-year odyssey","volume":"56","author":"Glassock","year":"2010","journal-title":"Am. J. Kidney Dis."},{"issue":"9","key":"10.1016\/j.exger.2023.112341_bb0095","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1038\/sj.ki.5000313","article-title":"Autocrine class 3 semaphorin system regulates slit diaphragm proteins and podocyte survival","volume":"69","author":"Guan","year":"2006","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.exger.2023.112341_bb0100","doi-asserted-by":"crossref","DOI":"10.1172\/JCI140453","article-title":"Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1-associated membranous nephropathy","volume":"131","author":"Haddad","year":"2021","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.exger.2023.112341_bb0105","doi-asserted-by":"crossref","first-page":"660","DOI":"10.3181\/00379727-100-24736","article-title":"Production of nephrotic syndrome in rats by Freund\u2019s adjuvants and rat kidney suspensions","volume":"100","author":"Heymann","year":"1959","journal-title":"Proc. Soc. Exp. Biol. Med."},{"issue":"8","key":"10.1016\/j.exger.2023.112341_bb0110","doi-asserted-by":"crossref","first-page":"3646","DOI":"10.4049\/jimmunol.1401267","article-title":"Glomerulopathy induced by immunization with a peptide derived from the goodpasture antigen \u03b13IV-NC1","volume":"194","author":"Hopfer","year":"2015","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0115","doi-asserted-by":"crossref","first-page":"8190","DOI":"10.1038\/s41598-020-64863-y","article-title":"Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1","volume":"10","author":"Jaber","year":"2020","journal-title":"Sci. Rep."},{"issue":"18","key":"10.1016\/j.exger.2023.112341_bb0120","doi-asserted-by":"crossref","first-page":"5557","DOI":"10.1073\/pnas.79.18.5557","article-title":"The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border","volume":"79","author":"Kerjaschki","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.exger.2023.112341_bb0125","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1084\/jem.157.2.667","article-title":"Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats","volume":"157","author":"Kerjaschki","year":"1983","journal-title":"J. Exp. Med."},{"issue":"4S","key":"10.1016\/j.exger.2023.112341_bb0130","first-page":"S1","article-title":"KDIGO 2021 clinical practice guideline for the management of glomerular diseases","volume":"100","author":"Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group","year":"2021","journal-title":"Kidney Int."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0135","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1093\/gerona\/gln055","article-title":"Induction of cellular senescence by secretory phospholipase A2 in human dermal fibroblasts through an ROS-mediated p53 pathway","volume":"64","author":"Kim","year":"2009","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"issue":"51","key":"10.1016\/j.exger.2023.112341_bb0140","doi-asserted-by":"crossref","first-page":"36598","DOI":"10.1074\/jbc.M113.488122","article-title":"Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease","volume":"288","author":"Kistler","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.exger.2023.112341_bb0145","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.822508","article-title":"Strategies towards antigen-specific treatments for membranous nephropathy","volume":"13","author":"K\u00f6llner","year":"2022","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0150","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1523-1755.2005.00415.x","article-title":"Th2 cytokines increase and stimulate B cells to produce IgG4 in idiopathic membranous nephropathy","volume":"68","author":"Kuroki","year":"2005","journal-title":"Kidney Int."},{"issue":"2","key":"10.1016\/j.exger.2023.112341_bb0155","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1681\/ASN.2017060664","article-title":"LDL receptor-related protein 2 (Megalin) as a target antigen in human kidney anti-brush border antibody Disease","volume":"29","author":"Larsen","year":"2018","journal-title":"J. Am. Soc. Nephrol."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0160","doi-asserted-by":"crossref","first-page":"2212081","DOI":"10.1080\/0886022X.2023.2212081","article-title":"Clinicopathological features and outcome in elderly patients with idiopathic membranous nephropathy","volume":"45","author":"Liang","year":"2023","journal-title":"Ren. Fail."},{"issue":"11","key":"10.1016\/j.exger.2023.112341_bb0165","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1042\/CS20160069","article-title":"IL-10-producing regulatory B-cells suppressed effector T-cells but enhanced regulatory T-cells in chronic HBV infection","volume":"130","author":"Liu","year":"2016","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.exger.2023.112341_bb0170","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.3389\/fimmu.2019.01809","article-title":"Immunological pathogenesis of membranous nephropathy: focus on PLA2R1 and its role","volume":"10","author":"Liu","year":"2019","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.exger.2023.112341_bb0175","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.kint.2019.07.014","article-title":"The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery","volume":"96","author":"van de Logt","year":"2019","journal-title":"Kidney Int."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0180","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s40620-014-0090-z","article-title":"Nationwide biopsy survey of renal diseases in the Czech Republic during the years 1994-2011","volume":"28","author":"Maixnerova","year":"2015","journal-title":"J. Nephrol."},{"key":"10.1016\/j.exger.2023.112341_bb0185","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.952235","article-title":"The alternative pathway is necessary and sufficient for complement activation by anti-THSD7A autoantibodies, which are predominantly IgG4 in membranous nephropathy","volume":"13","author":"Manral","year":"2022","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.exger.2023.112341_bb0190","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.4049\/jimmunol.1003451","article-title":"Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis","volume":"187","author":"Meyer-Schwesinger","year":"2011","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.exger.2023.112341_bb0195","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.kint.2019.10.022","article-title":"A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients","volume":"97","author":"Meyer-Schwesinger","year":"2020","journal-title":"Kidney Int."},{"issue":"2","key":"10.1016\/j.exger.2023.112341_bb0200","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1365-2249.1994.tb06532.x","article-title":"Proteinuria induced by anti-dipeptidyl peptidase IV (gp108); role of circulating and glomerular antigen","volume":"95","author":"Natori","year":"1994","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.exger.2023.112341_bb0205","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jaut.2015.02.004","article-title":"B-Cells induce regulatory T cells through TGF-\u03b2\/IDO production in A CTLA-4 dependent manner","volume":"59","author":"Nou\u00ebl","year":"2015","journal-title":"J. Autoimmun."},{"issue":"2","key":"10.1016\/j.exger.2023.112341_bb0210","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1681\/ASN.2015121308","article-title":"Renal aging: causes and consequences","volume":"28","author":"O\u2019Sullivan","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"issue":"4","key":"10.1016\/j.exger.2023.112341_bb0215","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/ki.1997.148","article-title":"Role of T cells in the mediation of Heymann nephritis. ii. Identification of Th1 and cytotoxic cells in glomeruli","volume":"51","author":"Penny","year":"1997","journal-title":"Kidney Int."},{"issue":"6","key":"10.1016\/j.exger.2023.112341_bb0220","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1172\/JCI200315645","article-title":"DNA damage is a novel response to sublytic complement C5b-9-induced injury in podocytes","volume":"111","author":"Pippin","year":"2003","journal-title":"J. Clin. Invest."},{"issue":"9","key":"10.1016\/j.exger.2023.112341_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0025065","article-title":"Receptor-mediated endocytosis of \u03b1-galactosidase A in human podocytes in Fabry disease","volume":"6","author":"Prabakaran","year":"2011","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0230","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1681\/ASN.0000000000000068","article-title":"Pathogenicity of human anti-PLA2R1 antibodies in minipigs: a pilot study","volume":"34","author":"Reinhard","year":"2023","journal-title":"J. Am. Soc. Nephrol."},{"issue":"9981","key":"10.1016\/j.exger.2023.112341_bb0235","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/S0140-6736(15)60731-0","article-title":"Pathophysiological advances in membranous nephropathy: time for a shift in patient\u2019s care","volume":"385","author":"Ronco","year":"2015","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0240","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1097\/MNH.0000000000000697","article-title":"Membranous nephropathy: current understanding of various causes in light of new target antigens","volume":"30","author":"Ronco","year":"2021","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0245","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/s41572-021-00303-z","article-title":"Membranous nephropathy","volume":"7","author":"Ronco","year":"2021","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0250","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.kint.2017.01.012","article-title":"B- and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab","volume":"92","author":"Rosenzwajg","year":"2017","journal-title":"Kidney Int."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0255","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.kint.2017.02.036","article-title":"Molecular mechanisms of renal aging","volume":"92","author":"Schmitt","year":"2017","journal-title":"Kidney Int."},{"issue":"16","key":"10.1016\/j.exger.2023.112341_bb0260","doi-asserted-by":"crossref","first-page":"7926","DOI":"10.1073\/pnas.1820892116","article-title":"Small-molecule factor B inhibitor for the treatment of complement-mediated diseases","volume":"116","author":"Schubart","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0265","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/s41467-023-36068-0","article-title":"The classical pathway triggers pathogenic complement activation in membranous nephropathy","volume":"14","author":"Seifert","year":"2023","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0270","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.kint.2023.01.003","article-title":"Mapping antigens of membranous nephropathy: almost there","volume":"103","author":"Sethi","year":"2023","journal-title":"Kidney Int."},{"issue":"6","key":"10.1016\/j.exger.2023.112341_bb0275","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1681\/ASN.2018080852","article-title":"Exostosin 1\/Exostosin 2-associated membranous nephropathy","volume":"30","author":"Sethi","year":"2019","journal-title":"J. Am. Soc. Nephrol."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0280","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.kint.2019.09.014","article-title":"Neural epidermal growth factor-like 1 protein (NELL-1) associated membranous nephropathy","volume":"97","author":"Sethi","year":"2020","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.exger.2023.112341_bb0285","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.kint.2020.05.030","article-title":"Semaphorin 3B-associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients","volume":"98","author":"Sethi","year":"2020","journal-title":"Kidney Int."},{"issue":"12","key":"10.1016\/j.exger.2023.112341_bb0290","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1681\/ASN.2007030342","article-title":"Intramolecular epitope spreading in Heymann nephritis","volume":"18","author":"Shah","year":"2007","journal-title":"J. Am. Soc. Nephrol."},{"issue":"8","key":"10.1016\/j.exger.2023.112341_bb0295","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/eci.12292","article-title":"Serum with phospholipase A2 receptor autoantibodies interferes with podocyte adhesion to collagen","volume":"44","author":"\u0160koberne","year":"2014","journal-title":"Eur. J. Clin. Investig."},{"key":"10.1016\/j.exger.2023.112341_bb0300","doi-asserted-by":"crossref","first-page":"1009864","DOI":"10.3389\/fimmu.2022.1009864","article-title":"The role of the complement system in primary membranous nephropathy: a narrative review in the era of new therapeutic targets","volume":"13","author":"So","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.exger.2023.112341_bb0305","article-title":"POS-032 human PLA2R-antibodies induce membranous nephropathy in minipigs and activate complement","volume":"7(6, Supplement):S451-S452","author":"Stahl","year":"2022","journal-title":"Kidney Int. Rep."},{"issue":"3","key":"10.1016\/j.exger.2023.112341_bb0310","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/MNH.0000000000000782","article-title":"Ageing, cellular senescence and chronic kidney disease: experimental evidence","volume":"31","author":"Tan","year":"2022","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"24","key":"10.1016\/j.exger.2023.112341_bb0315","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1056\/NEJMoa1409354","article-title":"Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy","volume":"371","author":"Tomas","year":"2014","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.exger.2023.112341_bb0320","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1172\/JCI85265","article-title":"Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy","volume":"126","author":"Tomas","year":"2016","journal-title":"J. Clin. Invest."},{"issue":"11","key":"10.1016\/j.exger.2023.112341_bb0325","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1681\/ASN.2017010030","article-title":"A heterologous model of thrombospondin type 1 domain-containing 7A-associated membranous nephropathy","volume":"28","author":"Tomas","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.exger.2023.112341_bb0330","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.kint.2022.09.008","article-title":"Podocyte expression of human phospholipase A2 receptor 1 causes immune-mediated membranous nephropathy in mice","volume":"103","author":"Tomas","year":"2023","journal-title":"Kidney Int."},{"issue":"23","key":"10.1016\/j.exger.2023.112341_bb0335","article-title":"A novel chimeric active immunization mouse model of PLA2R1-associated membranous nephropathy [published online ahead of print, 2023 Aug 18]","volume":"S0085-2538","author":"Tomas","year":"2023","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.exger.2023.112341_bb0340","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1046\/j.1523-1755.1999.00407.x","article-title":"Complement-mediated injury reversibly disrupts glomerular epithelial cell actin microfilaments and focal adhesions","volume":"55","author":"Topham","year":"1999","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.exger.2023.112341_bb0345","first-page":"502","article-title":"Experimental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. V. Fixed glomerular antigens in the pathogenesis of heterologous immune complex glomerulonephritis","volume":"38","author":"Van Damme","year":"1978","journal-title":"Lab. Investig."},{"issue":"20","key":"10.1016\/j.exger.2023.112341_bb0350","doi-asserted-by":"crossref","first-page":"6334","DOI":"10.1158\/0008-5472.CAN-13-0318","article-title":"PLA2R1 mediates tumor suppression by activating JAK2","volume":"73","author":"Vindrieux","year":"2013","journal-title":"Cancer Res."},{"issue":"7","key":"10.1016\/j.exger.2023.112341_bb0355","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1038\/sj.ki.5002426","article-title":"Kinetics of adaptive immunity to cationic bovine serum albumin-induced membranous nephropathy","volume":"72","author":"Wu","year":"2007","journal-title":"Kidney Int."},{"issue":"1","key":"10.1016\/j.exger.2023.112341_bb0360","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s10875-011-9614-7","article-title":"Pathogenic role of effector cells and immunoglobulins in cationic bovine serum albumin-induced membranous nephropathy","volume":"32","author":"Wu","year":"2012","journal-title":"J. Clin. Immunol."},{"issue":"12","key":"10.1016\/j.exger.2023.112341_bb0365","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1681\/ASN.2016010093","article-title":"Long-term exposure to air pollution and increased risk of membranous nephropathy in China","volume":"27","author":"Xu","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"issue":"Pt A","key":"10.1016\/j.exger.2023.112341_bb0370","article-title":"Cytokines network in primary membranous nephropathy","volume":"113","author":"Zhao","year":"2022","journal-title":"Int. Immunopharmacol."}],"container-title":["Experimental Gerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556523002620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0531556523002620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T03:51:47Z","timestamp":1759981907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0531556523002620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":74,"alternative-id":["S0531556523002620"],"URL":"https:\/\/doi.org\/10.1016\/j.exger.2023.112341","relation":{},"ISSN":["0531-5565"],"issn-type":[{"type":"print","value":"0531-5565"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Experimental models for elderly patients with membranous nephropathy: Application and advancements","name":"articletitle","label":"Article Title"},{"value":"Experimental Gerontology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exger.2023.112341","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"112341"}}