{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:52:34Z","timestamp":1776707554593,"version":"3.51.2"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"vor","delay-in-days":6367,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","exphem.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Hematology"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.exphem.2004.09.005","type":"journal-article","created":{"date-parts":[[2005,1,19]],"date-time":"2005-01-19T07:31:05Z","timestamp":1106119865000},"page":"108-119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":181,"title":["G-CSF\u2013primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs"],"prefix":"10.1016","volume":"33","author":[{"given":"Evangelia","family":"Yannaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Athanasiou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angeliki","family":"Xagorari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varnavas","family":"Constantinou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Batsis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis","family":"Kaloyannidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Proya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achilles","family":"Anagnostopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Fassas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exphem.2004.09.005_bib1","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1126\/science.279.5356.1528","article-title":"Muscle regeneration by bone marrow-derived myogenic progenitors","volume":"279","author":"Ferrari","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.exphem.2004.09.005_bib2","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/35070587","article-title":"Bone marrow cells regenerate infarcted myocardium","volume":"410","author":"Orlic","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.exphem.2004.09.005_bib3","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1038\/81326","article-title":"Purified hematopoietic stem cells can differentiate into hepatocytes in vivo","volume":"6","author":"Lagasse","year":"2000","journal-title":"Nat Med"},{"key":"10.1016\/j.exphem.2004.09.005_bib4","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1126\/science.290.5497.1775","article-title":"From marrow to brain: expression of neuronal phenotypes in adult mice","volume":"290","author":"Brazelton","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.exphem.2004.09.005_bib5","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0092-8674(01)00328-2","article-title":"Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell","volume":"105","author":"Krause","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.exphem.2004.09.005_bib6","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1182\/blood-2002-04-1076","article-title":"Hematopoietic origin of glomerular mesangial cells","volume":"101","author":"Masuya","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.exphem.2004.09.005_bib7","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1172\/JCI200316502","article-title":"In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion","volume":"111","author":"Ianus","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.exphem.2004.09.005_bib8","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1038\/nature01531","article-title":"Cell fusion is the principal source of bone marrow-derived hepatocytes","volume":"422","author":"Wang","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.exphem.2004.09.005_bib9","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/nature01539","article-title":"Transplanted bone marrow regenerates liver by cell fusion","volume":"422","author":"Vassilopoulos","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.exphem.2004.09.005_bib10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/sj.leu.2403184","article-title":"Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells \u2018hide out\u2019 in the bone marrow","volume":"18","author":"Ratajczak","year":"2004","journal-title":"Leukemia"},{"key":"10.1016\/j.exphem.2004.09.005_bib11","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1126\/science.284.5417.1168","article-title":"Bone marrow as a potential source of hepatic oval cells","volume":"284","author":"Petersen","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.exphem.2004.09.005_bib12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/hep.510310135","article-title":"Derivation of hepatocytes from bone marrow cells of mice after radiation-induced myeloablation","volume":"31","author":"Theise","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.exphem.2004.09.005_bib13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1053\/jhep.2000.9124","article-title":"Liver from bone marrow in humans","volume":"32","author":"Theise","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.exphem.2004.09.005_bib14","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1056\/NEJMoa3461002","article-title":"Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells","volume":"346","author":"Korbling","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.exphem.2004.09.005_bib15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/35018642","article-title":"Hepatocytes from non-hepatic adult stem cells","volume":"406","author":"Alison","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.exphem.2004.09.005_bib16","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.1182\/blood-2002-05-1338","article-title":"Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells","volume":"101","author":"Wang","year":"2003","journal-title":"Blood"},{"issue":"6893","key":"10.1016\/j.exphem.2004.09.005_bib17","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nature00870","article-title":"Pluripotency of mesenchymal stem cells derived from adult marrow","volume":"418","author":"Jiang","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.exphem.2004.09.005_bib18","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1182\/blood-2004-01-0259","article-title":"Formation of human hepatocytes by human hematopoietic stem cells in sheep","volume":"104","author":"Almeida-Porada","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.exphem.2004.09.005_bib19","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1172\/JCI17856","article-title":"Bone marrow stem cells contribute to repair of the ischemically injured renal tubule","volume":"112","author":"Kale","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.exphem.2004.09.005_bib20","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/nbt841","article-title":"Bone marrow-derived stem cells initiate pancreatic regeneration","volume":"21","author":"Hess","year":"2003","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.exphem.2004.09.005_bib21","doi-asserted-by":"crossref","first-page":"10344","DOI":"10.1073\/pnas.181177898","article-title":"Mobilized bone marrow cells repair the infracted heart, improving function and survival","volume":"98","author":"Orlic","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.exphem.2004.09.005_bib22","doi-asserted-by":"crossref","first-page":"7633","DOI":"10.1073\/pnas.83.20.7633","article-title":"Isolation and characterization of the cDNA for murine granulocyte colony-stimulating factor","volume":"83","author":"Tsuchiya","year":"1986","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.exphem.2004.09.005_bib23","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/314625a0","article-title":"Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells","volume":"314","author":"Nicola","year":"1985","journal-title":"Nature"},{"key":"10.1016\/j.exphem.2004.09.005_bib24","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jim.2003.07.007","article-title":"New tools for quantifying and visualizing adoptively transferred cells in recipient mice","volume":"282","author":"Moeller","year":"2003","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.exphem.2004.09.005_bib25","first-page":"677","article-title":"Ultrastructural alterations within hepatic parenchymal cells after carbon tetrachloride poisoning","volume":"Vol. 1","author":"Stenger","year":"1966"},{"key":"10.1016\/j.exphem.2004.09.005_bib26","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1172\/JCI1018","article-title":"Mechanisms of spontaneous resolution of rat liver fibrosis","volume":"102","author":"Iredale","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.exphem.2004.09.005_bib27","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/gut.46.4.443","article-title":"Is liver fibrosis reversible?","volume":"46","author":"Benyon","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.exphem.2004.09.005_bib28","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1093\/hmg\/2.12.2007","article-title":"The human SRY transcript","volume":"2","author":"Clepet","year":"1993","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.exphem.2004.09.005_bib29","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/(SICI)1521-1878(199803)20:3<264::AID-BIES10>3.0.CO;2-1","article-title":"Interactions between SRY and SOX genes in mammalian sex determination","volume":"20","author":"Graves","year":"1998","journal-title":"Bioassays"},{"key":"10.1016\/j.exphem.2004.09.005_bib30","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/mrd.1080390211","article-title":"The biochemical role of SRY in sex determination","volume":"39","author":"Harley","year":"1994","journal-title":"Mol Reprod Dev"},{"key":"10.1016\/j.exphem.2004.09.005_bib31","first-page":"133","article-title":"Induction of early immediate genes by tumor necrosis alpha contributes to liver repair following chemical-induced hepatotoxicity","volume":"25","author":"Bruccoleri","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.exphem.2004.09.005_bib32","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1053\/jhep.2001.24666","article-title":"Earlier expression of the transcription factor HFH-11B diminishes induction of p21CIP1\/WAF1 levels and accelerates mouse hepatocyte entry into S-phase following carbon tetrachloride liver injury","volume":"33","author":"Wang","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.exphem.2004.09.005_bib33","doi-asserted-by":"crossref","first-page":"11850","DOI":"10.1073\/pnas.1834198100","article-title":"Little evidence of bone marrow-derived hepatocytes in the replacement of injured liver","volume":"100","author":"Kanazawa","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.exphem.2004.09.005_bib34","first-page":"201","article-title":"Regeneration of heart muscle tissue: quantification of chimeric cardiomyocytes and endothelial cells following transplantation","volume":"19","author":"Thiele","year":"2004","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.exphem.2004.09.005_bib35","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/S0002-9440(10)63203-8","article-title":"Epithelial tissue chimerism after human hematopoietic cell transplantation is a real phenomenon","volume":"164","author":"Spyridonidis","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.exphem.2004.09.005_bib36","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0169-328X(95)00136-G","article-title":"Transcription of the Y chromosomal gene, Sry, in adult mouse brain","volume":"33","author":"Lahr","year":"1995","journal-title":"Mol Brain Res"},{"key":"10.1016\/j.exphem.2004.09.005_bib37","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/ncb1132","article-title":"Hematopoietic stem cells convert into liver cells within days without fusion","volume":"6","author":"Jang","year":"2004","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.exphem.2004.09.005_bib38","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1046\/j.1365-2141.2003.04745.x","article-title":"Elevation of serum hepatocyte growth factor during granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization","volume":"124","author":"Fujii","year":"2004","journal-title":"Br J Haematol"},{"key":"10.1016\/j.exphem.2004.09.005_bib39","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1172\/JCI21301","article-title":"Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners","volume":"113","author":"Camargo","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.exphem.2004.09.005_bib40","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/nm1062","article-title":"Myelomonocytic cells are sufficient for therapeutic cell fusion in liver","volume":"10","author":"Willenbring","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.exphem.2004.09.005_bib41","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.bcmd.2003.09.025","article-title":"Tissue-specific muscle, neural and liver stem\/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury","volume":"32","author":"Kucia","year":"2004","journal-title":"Blood Cells Mol Dis"},{"key":"10.1016\/j.exphem.2004.09.005_bib42","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0301-472X(02)00821-4","article-title":"Failure of adult marrow-derived stem cells to generate marrow stroma after successful hematopoietic stem cell transplantation","volume":"30","author":"Awaya","year":"2002","journal-title":"Exp Hematol"},{"key":"10.1016\/j.exphem.2004.09.005_bib43","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/S0301-472X(99)00101-0","article-title":"Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases","volume":"27","author":"Koc","year":"1999","journal-title":"Exp Hematol"},{"key":"10.1016\/j.exphem.2004.09.005_bib44","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1089\/scd.1.1997.6.447","article-title":"Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections","volume":"6","author":"Lazarus","year":"1997","journal-title":"J Hematother"},{"key":"10.1016\/j.exphem.2004.09.005_bib45","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1038\/sj.bmt.1701218","article-title":"Monocytes are the likely candidate \u2018stromal\u2019 cell in the G-CSF-mobilized peripheral blood","volume":"21","author":"Purton","year":"1998","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.exphem.2004.09.005_bib46","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1056\/NEJM199805143382004","article-title":"Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation","volume":"338","author":"Fox","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.exphem.2004.09.005_bib47","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1055\/s-2007-1007096","article-title":"Hepatocyte transplantation for the treatment of human disease","volume":"19","author":"Strom","year":"1999","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.exphem.2004.09.005_bib48","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1053\/gast.2000.20222","article-title":"Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis","volume":"119","author":"De Vree","year":"2000","journal-title":"Gastroenterology"}],"container-title":["Experimental Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301472X04003194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301472X04003194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:19:39Z","timestamp":1759565979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301472X04003194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0301472X04003194"],"URL":"https:\/\/doi.org\/10.1016\/j.exphem.2004.09.005","relation":{},"ISSN":["0301-472X"],"issn-type":[{"value":"0301-472X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"G-CSF\u2013primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs","name":"articletitle","label":"Article Title"},{"value":"Experimental Hematology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exphem.2004.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 International Society for Experimental Hematology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}