{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T08:14:10Z","timestamp":1789719250835,"version":"4.0.1"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"vor","delay-in-days":4906,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","exphem.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Hematology"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.exphem.2008.08.009","type":"journal-article","created":{"date-parts":[[2008,10,26]],"date-time":"2008-10-26T04:16:23Z","timestamp":1224994583000},"page":"87-91","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Dominant contribution of malignant endothelial cells to endotheliopoiesis in chronic myeloid leukemia"],"prefix":"10.1016","volume":"37","author":[{"given":"Jingyi","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenli","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yicheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunping","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shixuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfeng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exphem.2008.08.009_bib1","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1242\/dev.125.4.725","article-title":"A common precursor for hematopoietic and endothelial cells","volume":"125","author":"Choi","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.exphem.2008.08.009_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.immuni.2004.06.006","article-title":"Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties","volume":"21","author":"Wang","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.exphem.2008.08.009_bib3","first-page":"249","article-title":"Structure and function of sinusoidal endothelium of bone marrow","volume":"59B","author":"Tavassoli","year":"1981","journal-title":"Prog Clin Biol Res"},{"key":"10.1016\/j.exphem.2008.08.009_bib4","first-page":"349","article-title":"The bone marrow vascular niche: home of HSC differentiation and mobilization","volume":"20","author":"Kopp","year":"2005","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.exphem.2008.08.009_bib5","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/nri1779","article-title":"Bone-marrow haematopoietic-stem-cell niches","volume":"6","author":"Wilson","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.exphem.2008.08.009_bib6","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1016\/S0140-6736(00)02241-8","article-title":"Evidence from a leukaemia model for maintenance of vascular endothelium by bone-marrow-derived endothelial cells","volume":"355","author":"Gunsilius","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.exphem.2008.08.009_bib7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1056\/NEJMoa033153","article-title":"Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas","volume":"351","author":"Streubel","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.exphem.2008.08.009_bib8","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1182\/blood-2005-04-1768","article-title":"Neoplastic circulating endothelial cells in multiple myeloma with 13q14 deletion","volume":"107","author":"Rigolin","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.exphem.2008.08.009_bib9","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/sj.leu.2405069","article-title":"Immunophenotypic, cytogenetic and functional characterization of circulating endothelial cells in myelodysplastic syndromes","volume":"22","author":"Della Porta","year":"2008","journal-title":"Leukemia"},{"key":"10.1016\/j.exphem.2008.08.009_bib10","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1182\/blood-2004-07-2514","article-title":"Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics","volume":"105","author":"Fang","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.exphem.2008.08.009_bib11","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1242\/dev.120.9.2539","article-title":"Platelet endothelial cell adhesion molecule-1 (PECAM-1\/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development","volume":"120","author":"Baldwin","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.exphem.2008.08.009_bib12","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.4049\/jimmunol.141.6.1925","article-title":"Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line","volume":"141","author":"Gougos","year":"1988","journal-title":"J Immunol"},{"key":"10.1016\/j.exphem.2008.08.009_bib13","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1385\/SCR:1:3:277","article-title":"Hemangioblasts representing a functional endothelio-hematopoietic entity in ontogeny, postnatal life, and CML neovasculogenesis","volume":"1","author":"Prindull","year":"2005","journal-title":"Stem Cell Rev"},{"key":"10.1016\/j.exphem.2008.08.009_bib14","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.cb.06.110190.001245","article-title":"Cell biology of von Willebrand factor","volume":"6","author":"Wagner","year":"1990","journal-title":"Annu Rev Cell Biol"},{"key":"10.1016\/j.exphem.2008.08.009_bib15","series-title":"Diagnostic Cytogenetics","first-page":"151","article-title":"Classical and molecular cytogenetics of tumor cells","author":"Schlegelberger","year":"1999"},{"key":"10.1016\/j.exphem.2008.08.009_bib16","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/cyto.a.20480","article-title":"Circulating bone marrow-derived endothelial progenitor cells: characterization, mobilization, and therapeutic considerations in malignant disease","volume":"73","author":"Dome","year":"2008","journal-title":"Cytometry A"},{"key":"10.1016\/j.exphem.2008.08.009_bib17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2141.2008.07195.x","article-title":"Blood outgrowth endothelial cells from chronic myeloid leukemia patients are BCR\/ABL1 negative","volume":"142","author":"Otten","year":"2008","journal-title":"Br J Haematol"},{"key":"10.1016\/j.exphem.2008.08.009_bib18","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1182\/blood-2003-08-2734","article-title":"Reversal of bone marrow angiogenesis in chronic myeloid leukemia following imatinib mesylate (STI571) therapy","volume":"103","author":"Kvasnicka","year":"2004","journal-title":"Blood"}],"container-title":["Experimental Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301472X08004165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301472X08004165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:27:09Z","timestamp":1759566429000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301472X08004165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0301472X08004165"],"URL":"https:\/\/doi.org\/10.1016\/j.exphem.2008.08.009","relation":{},"ISSN":["0301-472X"],"issn-type":[{"value":"0301-472X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dominant contribution of malignant endothelial cells to endotheliopoiesis in chronic myeloid leukemia","name":"articletitle","label":"Article Title"},{"value":"Experimental Hematology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exphem.2008.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}