{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:41:59Z","timestamp":1761554519074,"version":"build-2065373602"},"reference-count":19,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EXPLORE"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.explore.2021.12.003","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T10:59:33Z","timestamp":1640257173000},"page":"714-718","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Siddha fasting in obese acute decompensated heart failure may improve hospital outcomes through empowerment and natural ketosis"],"prefix":"10.1016","volume":"18","author":[{"given":"Anand","family":"Chockalingam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Senthil","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio Sendra","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saivaroon","family":"Gajagowni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxwell","family":"Isaac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Poorna","family":"Karuparthi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kul","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selva","family":"Shunmugam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arul","family":"Amuthan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arpit","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chetan P.","family":"Hans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiruba","family":"Krishnaswamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smrita","family":"Dorairajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenguo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Flaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.explore.2021.12.003_bib0001","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s11897-013-0155-7","article-title":"The emerging epidemic of heart failure with preserved ejection fraction","volume":"10","author":"Oktay","year":"2013","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.explore.2021.12.003_bib0002","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1053\/j.ackd.2018.08.009","article-title":"Epidemiology of cardiorenal syndrome","volume":"25","author":"Uduman","year":"2018","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.explore.2021.12.003_bib0003","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41572-020-0151-7","article-title":"Acute heart failure","volume":"6","author":"Arrigo","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.explore.2021.12.003_bib0004","doi-asserted-by":"crossref","first-page":"858","DOI":"10.4103\/2230-8210.192921","article-title":"Fasting practices in Tamil Nadu and their importance for patients with diabetes","volume":"20","author":"Kannan","year":"2016","journal-title":"Indian J Endocrinol Metab"},{"key":"10.1016\/j.explore.2021.12.003_bib0005","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1161\/CIRCULATIONAHA.105.563817","article-title":"Cardioprotection by intermittent fasting in rats","volume":"112","author":"Ahmet","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.explore.2021.12.003_bib0006","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.yjmcc.2008.10.027","article-title":"Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF\/VEGF\/PI3K signaling pathway","volume":"46","author":"Katare","year":"2009","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.explore.2021.12.003_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.explore.2021.11.006","article-title":"Siddha Fasting in Morbidly Obese Heart Failure Patients Achieves Significant Weight Loss and Reduces Hospitalization","author":"Chockalingam","year":"2021","journal-title":"EXPLORE: J Sci Healing"},{"key":"10.1016\/j.explore.2021.12.003_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2020.12.065","article-title":"Therapeutic potential of ketone bodies for patients with cardiovascular disease: JACC focus seminar","author":"Yurista","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.explore.2021.12.003_bib0009","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1161\/CIRCULATIONAHA.118.036459","article-title":"Cardiovascular effects of treatment with the ketone body 3-hydroxybutyrate in chronic heart failure patients","volume":"139","author":"Nielsen","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.explore.2021.12.003_bib0010","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/0735-1097(96)00214-8","article-title":"Blood ketone bodies in congestive heart failure","volume":"28","author":"Lommi","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.explore.2021.12.003_bib0011","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1161\/01.HYP.33.2.658","article-title":"Low calorie diet enhances renal, hemodynamic, and humoral effects of exogenous atrial natriuretic peptide in obese hypertensives","volume":"33","author":"Dess\u00ec-Fulgheri","year":"1999","journal-title":"Hypertension"},{"key":"10.1016\/j.explore.2021.12.003_bib0012","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/j.1550-8528.1997.tb00590.x","article-title":"Suppression of sympathetic nervous system during fasting","volume":"5","author":"Young","year":"1997","journal-title":"Obes Res"},{"key":"10.1016\/j.explore.2021.12.003_bib0013","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3389\/fendo.2020.00217","article-title":"Fasting-induced natriuresis and SGLT: a new hypothesis for an old enigma","volume":"11","author":"Heyman","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.explore.2021.12.003_bib0014","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1056\/NEJMra1905136","article-title":"Effects of intermittent fasting on health, aging, and disease","volume":"381","author":"de Cabo","year":"2019","journal-title":"N Engl J Med"},{"key":"10.1016\/j.explore.2021.12.003_bib0015","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1016\/S0735-1097(02)02533-0","article-title":"Absence of postprandial surge in coronary blood flow distal to significant stenosis: a possible mechanism of postprandial angina","volume":"40","author":"Chung","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.explore.2021.12.003_bib0016","series-title":"Recipes For Immortality: Healing, Religion, and Community in South India","first-page":"80","author":"Weiss","year":"2009"},{"key":"10.1016\/j.explore.2021.12.003_bib0017","series-title":"MacMillan Encyclopedia of Buddhism","first-page":"214","article-title":"Martial Arts","author":"Powell","year":"2004"},{"key":"10.1016\/j.explore.2021.12.003_bib0018","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12906-018-2136-6","article-title":"Is fasting safe? A chart review of adverse events during medically supervised, water-only fasting","volume":"18","author":"Finnell","year":"2018","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.explore.2021.12.003_bib0019","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1161\/CIRCULATIONAHA.119.045033","article-title":"Implications of altered ketone metabolism and therapeutic ketosis in heart failure","volume":"141","author":"Selvaraj","year":"2020","journal-title":"Circulation"}],"container-title":["EXPLORE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550830721002500?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550830721002500?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:36:16Z","timestamp":1761554176000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550830721002500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S1550830721002500"],"URL":"https:\/\/doi.org\/10.1016\/j.explore.2021.12.003","relation":{},"ISSN":["1550-8307"],"issn-type":[{"type":"print","value":"1550-8307"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Siddha fasting in obese acute decompensated heart failure may improve hospital outcomes through empowerment and natural ketosis","name":"articletitle","label":"Article Title"},{"value":"EXPLORE","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.explore.2021.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}