{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T17:23:44Z","timestamp":1783185824384,"version":"3.54.6"},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EXPLORE"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.explore.2022.10.001","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T12:58:22Z","timestamp":1665406702000},"page":"439-444","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Modified Sipjeondaebo-tang (JAROTANG) for Henoch-Schonlein purpura nephritis (HSPN): Two case reports"],"prefix":"10.1016","volume":"19","author":[{"given":"Suyeon","family":"Cho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0943-9290","authenticated-orcid":false,"given":"Soobin","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Seon","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunju","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.explore.2022.10.001_bib0001","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.2340\/00015555-2733","article-title":"Henoch-Sch\u00f6nlein purpura: a literature review","volume":"97","author":"Hetland","year":"2017","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.explore.2022.10.001_bib0002","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1590\/S1807-59322008000200018","article-title":"Henoch-Schonlein purpura in adults","volume":"63","author":"Lopez Meiller","year":"2008","journal-title":"Clinics"},{"key":"10.1016\/j.explore.2022.10.001_bib0003","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1093\/ckj\/sfaa251","article-title":"IgA vasculitis (Henoch-Schonlein purpura): refractory and relapsing disease course in the adult population","volume":"14","author":"Van de Perre","year":"2021","journal-title":"Clin Kidney J"},{"key":"10.1016\/j.explore.2022.10.001_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.lpm.2020.104035","article-title":"Adult-onset IgA vasculitis (Henoch-Schonlein): update on therapy","volume":"49","author":"Maritati","year":"2020","journal-title":"Presse Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0005","doi-asserted-by":"crossref","DOI":"10.1155\/2010\/597648","article-title":"Henoch-Schonlein purpura-a case report and review of the literature","volume":"2010","author":"Sohagia","year":"2010","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.explore.2022.10.001_bib0006","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/s12882-018-1009-z","article-title":"Clinical impact of endocapillary proliferation according to the Oxford classification among adults with Henoch-Schonlein purpura nephritis: a multicenter retrospective cohort study","volume":"19","author":"Inagaki","year":"2018","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.explore.2022.10.001_bib0007","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12882-020-1691-5","article-title":"MEST-C pathological score and long-term outcomes of child and adult patients with Henoch-Schonlein purpura nephritis","volume":"21","author":"Yun","year":"2020","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.explore.2022.10.001_bib0008","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.autrev.2015.02.003","article-title":"IgA vasculitis (Henoch-Shonlein purpura) in adults: diagnostic and therapeutic aspects","volume":"14","author":"Audemard-Verger","year":"2015","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.explore.2022.10.001_bib0009","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/fnut.2018.00031","article-title":"Kampo medicines for frailty in locomotor disease","volume":"5","author":"Nakae","year":"2018","journal-title":"Front Nutr"},{"key":"10.1016\/j.explore.2022.10.001_bib0011","unstructured":"Ministry of Food and Drug Safety. Kyungbang Sipjeondaebo-tang Ex. Granule Ministry of Food and Drug Safety. Accessed 11 August 2022. https:\/\/nedrug.mfds.go.kr\/pbp\/CCBBB01\/getItemDetail?itemSeq=200005820; 2020."},{"key":"10.1016\/j.explore.2022.10.001_bib0012","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/1972527","article-title":"Correlation between traditional Chinese medicine symptom patterns and the renal function, immunologic function index, and blood coagulation index in patients with Henoch-Schonlein purpura nephritis","volume":"2018","author":"Dang","year":"2018","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0010","series-title":"Pathology in Korean Medicine","first-page":"315","article-title":"The compilation committee for pathology in Korean Medicine. Pattern identification based on Qi, blood, fluid-humor","author":"Yin","year":"2019"},{"key":"10.1016\/j.explore.2022.10.001_bib0013","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1136\/ard.2009.116657","article-title":"EULAR\/PRINTO\/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis Nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria","volume":"69","author":"Ozen","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.explore.2022.10.001_bib0014","first-page":"S34","article-title":"Revisiting clinical differences between hypersensitivity vasculitis and Henoch-Schonlein purpura in adults from a defined population","volume":"32","author":"Calvo-Rio","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.explore.2022.10.001_bib0015","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.3390\/jcm10112310","article-title":"IgA vasculitis and IgA nephropathy: same disease?","volume":"10","author":"Pillebout","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0016","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/1038206","article-title":"Hong Kong Chinese medicine clinical practice guideline for cancer palliative care: pain, constipation, and insomnia","volume":"2019","author":"Lam","year":"2019","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0017","series-title":"Acupuncture for IVF and Assisted Reproduction: An Integrated Approach to Treatment and Management","author":"Szmelskyj","year":"2014"},{"key":"10.1016\/j.explore.2022.10.001_bib0018","doi-asserted-by":"crossref","first-page":"299","DOI":"10.15188\/kjopp.2018.10.32.5.299","article-title":"Review on concept and clinical application of yin-deficiency\u2027blood-deficiency in donguibogam","volume":"32","author":"Lee","year":"2018","journal-title":"J Physiol Pathol Korean Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0019","doi-asserted-by":"crossref","first-page":"7191","DOI":"10.2147\/JIR.S341581","article-title":"The anti-inflammatory actions and mechanisms of acupuncture from acupoint to target organs via neuro-immune regulation","volume":"14","author":"Li","year":"2021","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.explore.2022.10.001_bib0020","doi-asserted-by":"crossref","DOI":"10.1093\/ecam\/nep236","article-title":"Acupuncture may stimulate anticancer immunity via activation of natural killer cells","volume":"2011","author":"Johnston","year":"2011","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0021","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s13000-019-0818-0","article-title":"Updated Oxford classification and the international study of kidney disease in children classification: application in predicting outcome of Henoch-Schonlein purpura nephritis","volume":"14","author":"Huang","year":"2019","journal-title":"Diagn Pathol"},{"key":"10.1016\/j.explore.2022.10.001_bib0022","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3346\/jkms.2014.29.2.198","article-title":"Differences in clinical manifestations and outcomes between adult and child patients with Henoch-Schonlein purpura","volume":"29","author":"Kang","year":"2014","journal-title":"J Korean Med Sci"},{"key":"10.1016\/j.explore.2022.10.001_bib0023","first-page":"62","article-title":"A case of atopic dermatitis successfully treated with Juzentaihoto (Kampo)","volume":"16","author":"Chino","year":"2010","journal-title":"Altern Ther Health Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0024","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2741\/4619","article-title":"The role of T cells in the development of Henoch-Schonlein purpura","volume":"23","author":"Li","year":"2018","journal-title":"Front Biosci"},{"key":"10.1016\/j.explore.2022.10.001_bib0025","doi-asserted-by":"crossref","first-page":"3785","DOI":"10.1007\/s00296-011-2266-3","article-title":"Investigation of the change in CD4(+) T cell subset in children with Henoch-Schonlein purpura","volume":"32","author":"Li","year":"2012","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.explore.2022.10.001_bib0026","first-page":"516","article-title":"Function of CD4(+) CD25(+) regulatory T cells in Henoch-Schonlein purpura nephritis in children","volume":"52","author":"Shao","year":"2014","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"10.1016\/j.explore.2022.10.001_bib0027","article-title":"The alterations in and the role of the Th17\/Treg balance in metabolic diseases","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.explore.2022.10.001_bib0028","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.intimp.2013.03.027","article-title":"The imbalance of Th17\/Treg in Chinese children with Henoch-Schonlein purpura","volume":"16","author":"Chen","year":"2013","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.explore.2022.10.001_bib0029","first-page":"411","article-title":"Role of regulatory T cells in pathogenesis of Henoch-Schonlein purpura in children","volume":"44","author":"Yang","year":"2006","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"10.1016\/j.explore.2022.10.001_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000518448","article-title":"Juzentaihoto exerts anti-allergic effects by inhibiting effector T-cell activation and inducing and\/or activating regulatory T cells in a murine model of contact hypersensitivity","volume":"183","author":"Tsuge","year":"2022","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.explore.2022.10.001_bib0031","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0254-6272(14)60048-0","article-title":"Effects of Chinese herbs in children with Henoch-Schonlein purpura nephritis: a randomized controlled trial","volume":"34","author":"Ding","year":"2014","journal-title":"J Tradit Chin Med"},{"key":"10.1016\/j.explore.2022.10.001_bib0032","first-page":"3323","article-title":"Clinical effect of combined western medicine and traditional Chinese medicine on children with Henoch-Schonlein purpura nephritis","volume":"13","author":"Liu","year":"2021","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.explore.2022.10.001_bib0033","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.3892\/etm.2013.1020","article-title":"A case of anaphylactoid purpura nephritis accompanied by pulmonary hemorrhage and review of the literature","volume":"5","author":"Ren","year":"2013","journal-title":"Exp Ther Med"}],"container-title":["EXPLORE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550830722001665?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550830722001665?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:37:37Z","timestamp":1761554257000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550830722001665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S1550830722001665"],"URL":"https:\/\/doi.org\/10.1016\/j.explore.2022.10.001","relation":{},"ISSN":["1550-8307"],"issn-type":[{"value":"1550-8307","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modified Sipjeondaebo-tang (JAROTANG) for Henoch-Schonlein purpura nephritis (HSPN): Two case reports","name":"articletitle","label":"Article Title"},{"value":"EXPLORE","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.explore.2022.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}