{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T08:12:00Z","timestamp":1788595920518,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","award":["CU_FRB640001_16_33_1"],"award-info":[{"award-number":["CU_FRB640001_16_33_1"]}],"id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["EXPLORE"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.explore.2026.103452","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T16:20:47Z","timestamp":1779466847000},"page":"103452","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advantages of artificial saliva containing Cuminum cyminum and Zingiber officinale on hemodialysis patients with xerostomia: Randomized clinical trials"],"prefix":"10.1016","volume":"22","author":[{"given":"Supamas","family":"Napavichayanun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattachai","family":"Srisawat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weerachai","family":"Chaijamorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7274-2431","authenticated-orcid":false,"given":"Pornanong","family":"Aramwit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.explore.2026.103452_bib0001","doi-asserted-by":"crossref","first-page":"7173","DOI":"10.2147\/IJGM.S375994","article-title":"Factors affecting quality of life in hemodialysis patients","volume":"15","author":"Yonata","year":"2022","journal-title":"Int J Gen Med"},{"issue":"5","key":"10.1016\/j.explore.2026.103452_bib0002","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1093\/ndt\/gfn707","article-title":"The mortality risk of overhydration in haemodialysis patients","volume":"24","author":"Wizemann","year":"2009","journal-title":"Nephrol Dial Transpl"},{"issue":"8","key":"10.1016\/j.explore.2026.103452_bib0003","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1093\/ndt\/gfg225","article-title":"Interactions between dialysis-related volume exposures, nutritional surrogates and mortality among ESRD patients","volume":"18","author":"Szczech","year":"2003","journal-title":"Nephrol Dial Transpl"},{"issue":"4","key":"10.1016\/j.explore.2026.103452_bib0004","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/S0272-6386(03)00908-9","article-title":"Salivary and lacrimal secretion is reduced in patients with ESRD","volume":"42","author":"Postorino","year":"2003","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0005","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/nrneph.2011.218","article-title":"Xerostomia in patients on chronic hemodialysis","volume":"8","author":"Bossola","year":"2012","journal-title":"Nat Rev Nephrol"},{"issue":"2","key":"10.1016\/j.explore.2026.103452_bib0006","doi-asserted-by":"crossref","DOI":"10.1038\/bdj.2007.47","article-title":"Oral and salivary changes in patients with end stage renal disease (ESRD): a two year follow-up study","volume":"202","author":"Bots","year":"2007","journal-title":"Br Dent J"},{"issue":"9","key":"10.1016\/j.explore.2026.103452_bib0007","first-page":"841","article-title":"Hyposalivation in elderly patients","volume":"72","author":"Gupta","year":"2006","journal-title":"J Can Dent Assoc"},{"issue":"4","key":"10.1016\/j.explore.2026.103452_bib0008","article-title":"Dry mouth dilemma: a comprehensive review of xerostomia in complete denture wearers","volume":"16","author":"Mhatre","year":"2024","journal-title":"Cureus"},{"issue":"6","key":"10.1016\/j.explore.2026.103452_bib0009","first-page":"336","article-title":"Evaluation of effects of Zingiber officinale on salivation in rats","volume":"49","author":"Chamani","year":"2011","journal-title":"Acta Med Iran"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0010","first-page":"231","article-title":"Ginger facilitates cholinergic activity possibly due to blockade of muscarinic autoreceptors in rat stomach fundus","volume":"20","author":"Ghayur","year":"2007","journal-title":"Pak J Pharm Sci"},{"issue":"4","key":"10.1016\/j.explore.2026.103452_bib0011","first-page":"192","article-title":"Comparative study of anti ulcer activity of aqueous extracts of leaves of Piper betel Linn and dried fruits of cuminum cyminum Linn and their combination in rats","volume":"1","author":"Afsara","year":"2013","journal-title":"Int J Adv Res"},{"key":"10.1016\/j.explore.2026.103452_bib0012","first-page":"4771","article-title":"Evaluation of cuminum cyminum and coriandrum sativum on Profenofos induced nephrotoxicity in Swiss albino mice","volume":"39","author":"Kumar","year":"2011","journal-title":"Elixir Appl Bot"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0013","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1021\/jf0487351","article-title":"Antibacterial activity of cuminum cyminum L. and carum carvi L. essential oils","volume":"53","author":"Lacobellis","year":"2005","journal-title":"J Agric Food Chem"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0014","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-68013-2","article-title":"New natural agonists of the transient receptor potential ankyrin 1 (TRPA1) channel","volume":"10","author":"Legrand","year":"2020","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.explore.2026.103452_bib0015","article-title":"A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases","volume":"30","author":"Alvarez-Berdugo","year":"2018","journal-title":"J Neurogastroenterol Motil"},{"key":"10.1016\/j.explore.2026.103452_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.eujim.2024.102396","article-title":"Safety and effect of a new artificial saliva containing zingiber officinale and cuminum cyminum on stimulating saliva secretion: in vitro, in vivo and preliminary clinical study","volume":"70","author":"Napavichayanun","year":"2024","journal-title":"Eur J Integr Med"},{"issue":"2","key":"10.1016\/j.explore.2026.103452_bib0017","first-page":"Zc13","article-title":"Effect of probiotic curd on salivary pH and Streptococcus mutans: a double blind parallel randomized controlled trial","volume":"10","author":"Srivastava","year":"2016","journal-title":"J Clin Diagn Res"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0018","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/ndt\/gfh675","article-title":"Chewing gum and a saliva substitute alleviate thirst and xerostomia in patients on haemodialysis","volume":"20","author":"Bots","year":"2005","journal-title":"Nephrol Dial Transpl"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0019","first-page":"38","article-title":"Oral health condition of older adults with different nutritional status in Chamni District, Buriram Province","volume":"24","author":"Sittichoktrakul","year":"2021","journal-title":"Khon Kaen Dent J"},{"key":"10.1016\/j.explore.2026.103452_bib0020","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.archoralbio.2016.05.001","article-title":"The effect of clinical setting on the unstimulated salivary flow rate","volume":"69","author":"Varoni","year":"2016","journal-title":"Arch Oral Biol"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0021","first-page":"93","article-title":"Symptom experiences, symptom management and quality of life in head and neck cancer patients with radiation induced xerostomia","volume":"15","author":"Niramon","year":"2009","journal-title":"J Thai Soc Ther Radiol Oncol"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0022","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0360-3016(01)01512-7","article-title":"Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer","volume":"50","author":"Eisbruch","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"10","key":"10.1016\/j.explore.2026.103452_bib0023","first-page":"6061","article-title":"Concordance of the WHO, RTOG, and CTCAE v4.0 grading scales for the evaluation of oral mucositis associated with chemoradiation therapy for the treatment of oral and oropharyngeal cancers","volume":"29","author":"Villa","year":"2021","journal-title":"Support Care Cancer"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0024","first-page":"12","article-title":"The Xerostomia Inventory: a multi-item approach to measuring dry mouth","volume":"16","author":"Thomson","year":"1999","journal-title":"Community Dent Health"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0025","first-page":"10","article-title":"Translation, validation and reliability of a Thai version of the xerostomia inventory","volume":"15","author":"Kasa","year":"2022","journal-title":"SWU Dent J"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0026","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12903-020-1006-z","article-title":"Oral impact on daily performance (OIDP) scale for use in Sri Lankan adolescents: a cross sectional modification and validation study","volume":"20","author":"Amilani","year":"2020","journal-title":"BMC Oral Health"},{"issue":"1","key":"10.1016\/j.explore.2026.103452_bib0027","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1186\/s12903-022-02576-6","article-title":"Comparison of the 1 and 2% pilocarpine mouthwash in a xerostomic population: a randomized clinical trial","volume":"22","author":"Motamed","year":"2022","journal-title":"BMC Oral Health"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0028","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.suponc.2011.02.005","article-title":"A phase III randomized, double-blind, placebo-controlled study of pilocarpine for vaginal dryness: north Central Cancer Treatment group study N04CA","volume":"9","author":"Loprinzi","year":"2011","journal-title":"J Support Oncol"},{"issue":"4","key":"10.1016\/j.explore.2026.103452_bib0029","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1002\/med.21476","article-title":"Comprehensive review of cardiovascular toxicity of drugs and related agents","volume":"38","author":"Mlad\u011bnka","year":"2018","journal-title":"Med Res Rev"},{"key":"10.1016\/j.explore.2026.103452_bib0030","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ctcp.2015.12.001","article-title":"Evaluation of the efficacy of a polyherbal mouthwash containing Zingiber officinale, Rosmarinus officinalis and Calendula officinalis extracts in patients with gingivitis: a randomized double-blind placebo-controlled trial","volume":"22","author":"Mahyari","year":"2016","journal-title":"Complement Ther Clin Pr"},{"issue":"15","key":"10.1016\/j.explore.2026.103452_bib0031","first-page":"37","article-title":"The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: a double-blind controlled study","volume":"8","author":"Shooriabi","year":"2016","journal-title":"Pharm Lett"},{"key":"10.1016\/j.explore.2026.103452_bib0032","first-page":"308","article-title":"The effect of ginger herbal spray on reducing xerostomia in patients with type II diabetes","volume":"7","author":"Mardani","year":"2017","journal-title":"Avicenna J Phytomed"},{"issue":"10","key":"10.1016\/j.explore.2026.103452_bib0033","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/j.1365-2842.2006.01718.x","article-title":"Safety and effectiveness of topical dry mouth products containing olive oil, betaine, and xylitol in reducing xerostomia for polypharmacy-induced dry mouth","volume":"34","author":"Ship","year":"2007","journal-title":"J Oral Rehabil"},{"issue":"3","key":"10.1016\/j.explore.2026.103452_bib0034","first-page":"311","article-title":"The clinical effectiveness of Ginger (Zingiber officinale) in adults with osteoarthritis","volume":"6","author":"Leach","year":"2008","journal-title":"Int J Evid Based Heal"},{"issue":"4","key":"10.1016\/j.explore.2026.103452_bib0035","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ctcp.2014.10.001","article-title":"Effect of cumin powder on body composition and lipid profile in overweight and obese women","volume":"20","author":"Zare","year":"2014","journal-title":"Complement Ther Clin Pr"},{"issue":"10","key":"10.1016\/j.explore.2026.103452_bib0036","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0141119","article-title":"The effect of ginger (Zingiber officinale) on platelet aggregation: a systematic literature review","volume":"10","author":"Marx","year":"2015","journal-title":"PLoS One"}],"container-title":["EXPLORE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550830726001400?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550830726001400?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T07:36:44Z","timestamp":1788593804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550830726001400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1550830726001400"],"URL":"https:\/\/doi.org\/10.1016\/j.explore.2026.103452","relation":{},"ISSN":["1550-8307"],"issn-type":[{"value":"1550-8307","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advantages of artificial saliva containing Cuminum cyminum and Zingiber officinale on hemodialysis patients with xerostomia: Randomized clinical trials","name":"articletitle","label":"Article Title"},{"value":"EXPLORE","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.explore.2026.103452","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103452"}}