{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:01:34Z","timestamp":1771002094400,"version":"3.50.1"},"reference-count":53,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1016\/j.expneurol.2006.02.014","type":"journal-article","created":{"date-parts":[[2006,4,18]],"date-time":"2006-04-18T15:18:47Z","timestamp":1145373527000},"page":"275-282","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["Fluoxetine inhibits cortical spreading depression in weaned and adult rats suckled under favorable and unfavorable lactation conditions"],"prefix":"10.1016","volume":"200","author":[{"given":"\u00c2ngela Am\u00e2ncio","family":"dos Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Calado Ferreira","family":"Pinheiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise Sandrelly Cavalcanti","family":"de Lima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirella Gondim","family":"Ozias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuella Batista","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nat\u00e1lia Xavier","family":"Guimar\u00e3es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rubem Carlos Ara\u00fajo","family":"Guedes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.expneurol.2006.02.014_bib1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/1028415021000033776","article-title":"Nutrition and brain function: a multidisciplinary virtual symposium","volume":"5","author":"Almeida","year":"2002","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib2","article-title":"Inhibitory effect of fluoxetine on the propagation of cortical spreading depression in normal and malnourished young rats","author":"Am\u00e2ncio-dos-Santos","year":"2004"},{"key":"10.1016\/j.expneurol.2006.02.014_bib3","first-page":"889","article-title":"Enhanced rate of cortical spreading depression due to malnutrition: prevention by dietary protein supplementation","volume":"23","author":"Andrade","year":"1990","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib4","series-title":"5-Hydroxytryptamine Mechanisms in Primary Headaches","first-page":"236","article-title":"Effects of dihydroergotamine on spreading depression","author":"Barkley","year":"1992"},{"key":"10.1016\/j.expneurol.2006.02.014_bib5","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/15622970510029731","article-title":"Very early treatment with fluoxetine and reboxetine causing long-lasting change of the serotonin but not the noradrenaline transporter in the frontal cortex of rats","volume":"6","author":"Bock","year":"2005","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.expneurol.2006.02.014_bib6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0361-9230(00)00334-8","article-title":"Permanent and transitory morphometric changes of NADPH-diaphorase-containing neurons in the rat visual cortex after early malnutrition","volume":"53","author":"Borba","year":"2000","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.expneurol.2006.02.014_bib7","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF02761776","article-title":"Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study","volume":"10","author":"Boyer","year":"1998","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib8","first-page":"347","article-title":"Effect of d-fenfluramine on cortical spreading depression in rats","volume":"28","author":"Cabral-Filho","year":"1995","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0304-3940(01)01736-0","article-title":"Cortical spreading depression during streptozotocin-induced hyperglycemia in nutritionally normal and early-malnourished rats","volume":"303","author":"Costa-Cruz","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.expneurol.2006.02.014_bib10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1080\/10284150412331281031","article-title":"Malnutrition and REM-sleep deprivation modulate in rats the impairment of spreading depression by a single sub-convulsing dose of pilocarpine","volume":"7","author":"de-Vasconcelos","year":"2004","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib11","series-title":"Applied Neurochemistry","first-page":"287","article-title":"Vulnerable periods in developing brain","author":"Dobbing","year":"1968"},{"key":"10.1016\/j.expneurol.2006.02.014_bib12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/1028415X.1998.11747230","article-title":"Dietary antioxidant deficiency facilitates cortical spreading depression induced by photoactivated riboflavin","volume":"1","author":"El-Bach\u00e1","year":"1998","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib13","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/0013-4694(87)90213-6","article-title":"Ketamine blockade of cortical spreading depression in rats","volume":"66","author":"Gorelova","year":"1987","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.expneurol.2006.02.014_bib14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0165-0173(01)00081-9","article-title":"Spreading depression: a review of the clinical relevance","volume":"38","author":"Gorji","year":"2001","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.expneurol.2006.02.014_bib15","doi-asserted-by":"crossref","first-page":"2233S","DOI":"10.1093\/jn\/125.suppl_8.2233S","article-title":"A review of studies of the effect of severe malnutrition on mental development","volume":"125","author":"Grantham-McGregor","year":"1995","journal-title":"J. Nutr."},{"key":"10.1016\/j.expneurol.2006.02.014_bib16","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0022-3476(98)70357-9","article-title":"The development of low birth weight term infants and the effects of the environment in Northeast Brazil","volume":"132","author":"Grantham-McGregor","year":"1998","journal-title":"J. Pediatr."},{"key":"10.1016\/j.expneurol.2006.02.014_bib17","first-page":"445","article-title":"On some conditions that influence cortical spreading depression","volume":"56","author":"Guedes","year":"1984","journal-title":"An. Acad. Bras. Cienc."},{"key":"10.1016\/j.expneurol.2006.02.014_bib18","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0920-1211(96)01017-0","article-title":"Blockade of spreading depression in chronic epileptic rats: reversion by diazepam","volume":"27","author":"Guedes","year":"1997","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib19","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/BF00237123","article-title":"Influence of ionic alterations produced by gastric washing on cortical spreading depression","volume":"39","author":"Guedes","year":"1980","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib20","first-page":"1241","article-title":"Effect of ethanol on cortical spreading depression","volume":"26","author":"Guedes","year":"1993","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib21","first-page":"639","article-title":"Propagation of cortical spreading depression in malnourished rats: facilitatory effect of dietary protein deficiency","volume":"20","author":"Guedes","year":"1987","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib22","series-title":"Frontiers in Excitatory Amino Acid Research","first-page":"667","article-title":"Excitatory amino acids and cortical spreading depression","author":"Guedes","year":"1988"},{"key":"10.1016\/j.expneurol.2006.02.014_bib23","series-title":"Spreading Depression","first-page":"17","article-title":"GABAergic mechanisms involved in cortical spreading depression in normal and early malnourished rats","volume":"vol. 23","author":"Guedes","year":"1992"},{"key":"10.1016\/j.expneurol.2006.02.014_bib24","first-page":"1407","article-title":"Effect of aging on cortical spreading depression","volume":"29","author":"Guedes","year":"1996","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib25","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/10284150290018937","article-title":"Citalopram has an antagonistic action on cortical spreading depression in well-nourished and early-malnourished adult rats","volume":"5","author":"Guedes","year":"2002","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib26","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/BF01943871","article-title":"Developmental pattern of serotonin synthesizing enzyme in the brain of postnatally malnourished rats","volume":"29","author":"Hernandez","year":"1973","journal-title":"Experientia"},{"key":"10.1016\/j.expneurol.2006.02.014_bib27","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0163-7258(99)00048-0","article-title":"Pharmacokinetics of selective serotonin reuptake inhibitors","volume":"85","author":"Hiemke","year":"2000","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.expneurol.2006.02.014_bib28","first-page":"311","article-title":"Chronic administration of citalopram inhibited El mouse convulsions and decreased monoamine oxidase-A activity","volume":"48","author":"Kabuto","year":"1994","journal-title":"Acta Med. Okayama"},{"key":"10.1016\/j.expneurol.2006.02.014_bib29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0165-3806(01)00292-9","article-title":"Effects of prenatal protein malnutrition and neonatal stress on CNS responsiveness","volume":"132","author":"Kehoe","year":"2001","journal-title":"Brain Res. Dev. Brain Re.s"},{"key":"10.1016\/j.expneurol.2006.02.014_bib30","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1097\/00001756-199908200-00039","article-title":"Effects of ionotropic glutamate receptor blockade and 5-HT1A receptor activation on spreading depression in rat neocortical slices","volume":"10","author":"Kr\u00fcger","year":"1999","journal-title":"NeuroReport"},{"key":"10.1016\/j.expneurol.2006.02.014_bib31","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1152\/jn.1944.7.6.359","article-title":"Spreading depression of activity in the cerebral cortex","volume":"7","author":"Le\u00e3o","year":"1944","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.expneurol.2006.02.014_bib32","series-title":"Experimental Models of Epilepsy","first-page":"173","article-title":"Spreading depression","author":"Le\u00e3o","year":"1972"},{"key":"10.1016\/j.expneurol.2006.02.014_bib33","series-title":"Migraine: Basic Mechanisms and Treatment","author":"Lehmenk\u00fchler","year":"1993"},{"key":"10.1016\/j.expneurol.2006.02.014_bib34","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0306-4522(98)00106-7","article-title":"Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation","volume":"86","author":"Lu","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.expneurol.2006.02.014_bib35","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1590\/S0100-879X2001000100015","article-title":"Reduction of intraspecific aggression in adult rats by neonatal treatment with a selective serotonin reuptake inhibitor","volume":"34","author":"Manh\u00e3es-de-Castro","year":"2001","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib36","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/0006-8993(88)90690-7","article-title":"Evidence for a role of the N-methyl-d-aspartate (NMDA) receptor in cortical spreading depression in the rat","volume":"457","author":"Marrannes","year":"1988","journal-title":"Brain Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib37","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0149-7634(78)90059-3","article-title":"The effects of protein malnutrition on the developing nervous system in the rat","volume":"2","author":"Morgane","year":"1978","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.expneurol.2006.02.014_bib38","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0149-7634(05)80234-9","article-title":"Prenatal malnutrition and development of the brain","volume":"17","author":"Morgane","year":"1993","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.expneurol.2006.02.014_bib39","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.1748-1716.1992.tb09451.x","article-title":"NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain","volume":"146","author":"Nellgard","year":"1992","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.expneurol.2006.02.014_bib40","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1751-1097.1989.tb04153.x","article-title":"Elicitation of spreading depression by rose Bengal photodynamic action","volume":"50","author":"Netto","year":"1989","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.expneurol.2006.02.014_bib41","first-page":"703","article-title":"The worldwide magnitude of protein-energy malnutrition: an overview from the WHO global database on child growth","volume":"71","author":"Onis","year":"1993","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.expneurol.2006.02.014_bib42","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/1028415X.1998.11747211","article-title":"NADPH-diaphorase containing neurons and biocytin-labelled axon terminals in the visual cortex of adult rats malnourished during development","volume":"1","author":"Pican\u00e7o-Diniz","year":"1998","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib43","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0006-8993(00)02400-8","article-title":"Sumatriptan modifies cortical free radical release during cortical spreading depression. A novel antimigraine action for sumatriptan?","volume":"870","author":"Read","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib44","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1590\/S0100-879X1997000500015","article-title":"Spreading depression is facilitated in adult rats previously submitted to short episodes of malnutrition during the lactation period","volume":"30","author":"Rocha-de-Melo","year":"1997","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib45","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/10284150400001961","article-title":"NADPH-diaphorase histochemical labeling patterns in the hippocampal neuropil and visual cortical neurons in weaned rats reared during lactation on different litter sizes","volume":"7","author":"Rocha-de-Melo","year":"2004","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib46","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0006-8993(74)91012-9","article-title":"Effects of neonatal food deprivation on cortical spines and dendritic development of the rat","volume":"73","author":"Salas","year":"1974","journal-title":"Brain Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib47","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/S0028-3908(97)00134-2","article-title":"Serotonin inhibits epileptiform discharge by activation of 5-HT1A receptors in CA1 pyramidal neurons","volume":"36","author":"Salgado-Commissariat","year":"1997","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.expneurol.2006.02.014_bib48","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/1028415X.2000.11747301","article-title":"Long-lasting effects of early environmental stimulation on cortical spreading depression in normal and early malnourished adult rats","volume":"3","author":"Santos-Monteiro","year":"2000","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.expneurol.2006.02.014_bib49","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.neulet.2005.08.040","article-title":"Shrimp carotenoids protect the developing rat cerebral cortex against the effects of ethanol on cortical spreading depression","volume":"391","author":"Souza-Bezerra","year":"2005","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.expneurol.2006.02.014_bib50","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/0014-4886(75)90214-9","article-title":"Ontogeny of the levels of biogenic amines in various parts of the brain and in peripheral tissues in normal and protein malnourished rats","volume":"49","author":"Stern","year":"1975","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2006.02.014_bib51","first-page":"533","article-title":"A regional basic diet from Northeast Brazil as a dietary model of experimental malnutrition","volume":"40","author":"Teod\u00f3sio","year":"1990","journal-title":"Arch. Latinoam. Nutr."},{"key":"10.1016\/j.expneurol.2006.02.014_bib52","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0166-4328(96)00071-X","article-title":"Serotonin as a development signal","volume":"73","author":"Whitaker-Azmitia","year":"1996","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.expneurol.2006.02.014_bib53","first-page":"1277","article-title":"Differential effect of changes of blood glucose levels on the velocity of propagation of cortical spreading depression in normal and malnourished rats","volume":"24","author":"Ximenes-da-Silva","year":"1991","journal-title":"Braz. J. Med. Biol. Res."}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488606000690?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488606000690?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:46Z","timestamp":1755648046000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488606000690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S0014488606000690"],"URL":"https:\/\/doi.org\/10.1016\/j.expneurol.2006.02.014","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fluoxetine inhibits cortical spreading depression in weaned and adult rats suckled under favorable and unfavorable lactation conditions","name":"articletitle","label":"Article Title"},{"value":"Experimental Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.expneurol.2006.02.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}