{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T22:56:08Z","timestamp":1794264968346,"version":"4.9.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008459","name":"University of Calgary","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008459","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008920","name":"University of Saskatchewan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008920","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.expneurol.2009.09.020","type":"journal-article","created":{"date-parts":[[2009,10,2]],"date-time":"2009-10-02T04:23:39Z","timestamp":1254457419000},"page":"192-202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":313,"title":["Brief post-surgical electrical stimulation accelerates axon regeneration and muscle reinnervation without affecting the functional measures in carpal tunnel syndrome patients"],"prefix":"10.1016","volume":"223","author":[{"given":"Tessa","family":"Gordon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasim","family":"Amirjani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Ming","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.expneurol.2009.09.020_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.expneurol.2007.08.005","article-title":"One hour electrical stimulation accelerates functional recovery after femoral nerve repair","volume":"208","author":"Ahlborn","year":"2007","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib2","doi-asserted-by":"crossref","first-page":"4381","DOI":"10.1046\/j.1460-9568.2000.01341.x","article-title":"Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons","volume":"12","author":"Al Majed","year":"2000","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib3","doi-asserted-by":"crossref","first-page":"2602","DOI":"10.1523\/JNEUROSCI.20-07-02602.2000","article-title":"Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration","volume":"20","author":"Al Majed","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib4","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1023\/B:CEMN.0000022770.66463.f7","article-title":"Electrical stimulation accelerates and enhances expression of regeneration-associated genes in regenerating rat femoral motoneurons","volume":"24","author":"Al Majed","year":"2004","journal-title":"Cell Mol. Neurobiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib5","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0363-5023(87)80189-2","article-title":"The repeatability of testing with Semmes-Weinstein monofilaments","volume":"12","author":"Bell-Krotoski","year":"1987","journal-title":"J. Hand Surg. [Am]"},{"key":"10.1016\/j.expneurol.2009.09.020_bib6","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1046\/j.1460-9568.2002.01891.x","article-title":"A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor","volume":"15","author":"Boyd","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib7","doi-asserted-by":"crossref","first-page":"6631","DOI":"10.1523\/JNEUROSCI.22-15-06631.2002","article-title":"Electrical stimulation promotes motoneuron regeneration without increasing its speed or conditioning the neuron","volume":"22","author":"Brushart","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib8","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.expneurol.2005.02.007","article-title":"Electrical stimulation restores the specificity of sensory axon regeneration","volume":"194","author":"Brushart","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib9","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/mus.880160404","article-title":"The estimated numbers and relative sizes of thenar motor units as selected by multiple point stimulation in young and older adults","volume":"16","author":"Doherty","year":"1993","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.expneurol.2009.09.020_bib10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1152\/jappl.1997.82.1.93","article-title":"Age related changes in human thenar motor unit twitch contractile properties","volume":"82","author":"Doherty","year":"1997","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib11","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/00004691-199511000-00004","article-title":"Methods for estimating the numbers of motor units in human muscles","volume":"12","author":"Doherty","year":"1995","journal-title":"J. Clin. Neurophysiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib12","series-title":"Electrodiagnostic medicine","author":"Dumitru","year":"1995"},{"key":"10.1016\/j.expneurol.2009.09.020_bib13","first-page":"158","article-title":"Electrical stimulation promotes peripheral axon regeneration by enhanced neuronal neurotrophin signaling","volume":"67","author":"English","year":"2007","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib14","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1002\/mus.880181211","article-title":"Thenar motor unit number estimates using the multiple point stimulation technique: reproducibility studies in ALS patients and normal subjects","volume":"18","author":"Felice","year":"1995","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.expneurol.2009.09.020_bib15","doi-asserted-by":"crossref","first-page":"3876","DOI":"10.1523\/JNEUROSCI.15-05-03876.1995","article-title":"Contributing factors to poor functional recovery after delayed nerve repair: prolonged axotomy","volume":"15","author":"Fu","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib16","doi-asserted-by":"crossref","first-page":"3886","DOI":"10.1523\/JNEUROSCI.15-05-03886.1995","article-title":"Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation","volume":"15","author":"Fu","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF02740621","article-title":"The cellular and molecular basis of peripheral nerve regeneration","volume":"14","author":"Fu","year":"1997","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib18","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.expneurol.2007.01.040","article-title":"Electrical stimulation promotes sensory neuron regeneration and growth-associated gene expression","volume":"205","author":"Geremia","year":"2007","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib19","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1523\/JNEUROSCI.11-07-02157.1991","article-title":"Axotomy-induced changes in rabbit hindlimb nerves and the effects of chronic electrical stimulation","volume":"11","author":"Gordon","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib20","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1085-9489.2003.03029.x","article-title":"Experimental strategies to promote functional recovery after peripheral nerve injuries","volume":"8","author":"Gordon","year":"2003","journal-title":"J. Peripher. Nerv. Syst."},{"key":"10.1016\/j.expneurol.2009.09.020_bib21","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1227\/01.NEU.0000335650.09473.D3","article-title":"Accelerating axon growth to overcome limitations in functional recovery after peripheral nerve injury","volume":"65","author":"Gordon","year":"2009","journal-title":"Neurosurgery"},{"key":"10.1016\/j.expneurol.2009.09.020_bib46","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.expneurol.2007.06.020","article-title":"The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury","volume":"209","author":"Hannila","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib22","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/micr.1920100216","article-title":"Interpretation of cutaneous pressure threshold (Semmes\u2013Weinstein monofilament measurement) following median nerve repair and sensory reeducation in the adult","volume":"10","author":"Imai","year":"1989","journal-title":"Microsurgery"},{"key":"10.1016\/j.expneurol.2009.09.020_bib23","series-title":"Kline and Hudson's Nerve Injuries : Operative Results for Major Nerve Injuries, Entrapments and Tumors","author":"Kline","year":"2008"},{"key":"10.1016\/j.expneurol.2009.09.020_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3346\/jkms.2003.18.1.103","article-title":"Clinical usefulness of the two-site Semmes-Weinstein monofilament test for detecting diabetic peripheral neuropathy","volume":"18","author":"Lee","year":"2003","journal-title":"J. Korean Med. Sci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib25","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.2106\/00004623-199311000-00002","article-title":"A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome","volume":"75","author":"Levine","year":"1993","journal-title":"J. Bone Joint Surg. [Am.]"},{"key":"10.1016\/j.expneurol.2009.09.020_bib26","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0266-7681(94)90068-X","article-title":"Tubular repair of the median nerve in the human forearm\u2014preliminary findings","volume":"19","author":"Lundborg","year":"1994","journal-title":"J. Hand Surg. [Br]"},{"key":"10.1016\/j.expneurol.2009.09.020_bib27","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/00004691-199511000-00003","article-title":"Motor-unit estimation: the beginning","volume":"12","author":"McComas","year":"1995","journal-title":"J. Clin. Neurophysiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib28","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1136\/jnnp.34.4.453","article-title":"Functional compensation in partially denervated muscles","volume":"34","author":"McComas","year":"1971","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.expneurol.2009.09.020_bib29","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1016\/j.clinph.2004.03.022","article-title":"A correlative electrophysiologic study of nerve fiber involvement in carpal tunnel syndrome using current perception thresholds","volume":"115","author":"Nishimura","year":"2004","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib30","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0006-8993(83)90360-8","article-title":"Electrical stimulation of regenerating nerve and its effect on motor recovery","volume":"272","author":"Nix","year":"1983","journal-title":"Brain Res."},{"key":"10.1016\/j.expneurol.2009.09.020_bib31","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/00000637-198711000-00008","article-title":"A model of chronic nerve compression in the rat","volume":"19","author":"O'Brien","year":"1987","journal-title":"Ann. Plast. Surg."},{"key":"10.1016\/j.expneurol.2009.09.020_bib32","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1600-0404.1997.tb00271.x","article-title":"Neurophysiological classification and sensitivity in 500 carpal tunnel syndrome hands","volume":"96","author":"Padua","year":"1997","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.expneurol.2009.09.020_bib33","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0304-3940(85)90203-4","article-title":"Acceleration of peripheral nerve regeneration after crush injury in rat","volume":"59","author":"Pockett","year":"1985","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.expneurol.2009.09.020_bib34","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1016\/j.clinph.2008.07.219","article-title":"Test retest reliability of a modified multiple point stimulation technique for motor unit number estimation","volume":"119","author":"Porter","year":"2008","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib35","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1017\/S0317167100008568","article-title":"Motor unit number estimation in neuromuscular disease","volume":"35","author":"Rashidipour","year":"2008","journal-title":"Can J. Neurol. Sci."},{"key":"10.1016\/j.expneurol.2009.09.020_bib36","series-title":"Carpal Tunnel Syndrome and Other Disorders of the Median Nerve","first-page":"263","article-title":"Surgical treatment of carpal tunnel syndrome","author":"Rosenbaum","year":"1993"},{"key":"10.1016\/j.expneurol.2009.09.020_bib37","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.expneurol.2009.04.031","article-title":"Electrical stimulation and testosterone differentially enhance expression of regeneration-associated genes","volume":"223","author":"Sharma","year":"2010","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib38","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/1098-1136(200012)32:3<234::AID-GLIA40>3.0.CO;2-3","article-title":"Effects of short- and long-term Schwann cell denervation on peripheral nerve regeneration, myelination, and size","volume":"32","author":"Sulaiman","year":"2000","journal-title":"GLIA"},{"key":"10.1016\/j.expneurol.2009.09.020_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1001\/archneurpsyc.1947.02300300011001","article-title":"Rate of regeneration in human peripheral nerves","volume":"58","author":"Sunderland","year":"1947","journal-title":"Arch. Neurol. Psychiatry"},{"key":"10.1016\/j.expneurol.2009.09.020_bib40","series-title":"Nerve and Nerve Injuries","author":"Sunderland","year":"1978"},{"key":"10.1016\/j.expneurol.2009.09.020_bib41","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.expneurol.2007.11.007","article-title":"Electrical stimulation of intact peripheral sensory axons in rats promotes outgrowth of their central projections","volume":"210","author":"Udina","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib42","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1006\/exnr.1993.1147","article-title":"Adult spinal motoneurons remain viable despite prolonged absence of functional synaptic contact with muscle","volume":"123","author":"Vanden Noven","year":"1993","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib43","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1212\/01.wnl.0000327643.05073.eb","article-title":"Motor axon loss is associated with hand dysfunction in Charcot\u2013Marie\u2013Tooth disease 1a","volume":"71","author":"Videler","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.expneurol.2009.09.020_bib44","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/cne.20436","article-title":"Pathway sampling by regenerating peripheral axons","volume":"485","author":"Witzel","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.expneurol.2009.09.020_bib45","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/(SICI)1098-1136(199706)20:2<87::AID-GLIA1>3.0.CO;2-1","article-title":"The expression of the low affinity nerve growth factor receptor in long-term denervated Schwann cells","volume":"20","author":"You","year":"1997","journal-title":"GLIA"}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488609004075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488609004075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:44:27Z","timestamp":1762148667000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488609004075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0014488609004075"],"URL":"https:\/\/doi.org\/10.1016\/j.expneurol.2009.09.020","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.12152956.13358054","asserted-by":"object"}]},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brief post-surgical electrical stimulation accelerates axon regeneration and muscle reinnervation without affecting the functional measures in carpal tunnel syndrome patients","name":"articletitle","label":"Article Title"},{"value":"Experimental Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.expneurol.2009.09.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}